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  • NS e-input
    ...of substrates for the [[N-pathway control state]] and [[S-pathway control state]] through Complexes [[CI]] and [[CII]] simultaneously into the [[Q-junction
    1 KB (149 words) - 18:49, 1 January 2021
  • O2k-Publications: S
    [[File:SUIT-catg FNSGp.jpg|right|200px|link=Electron-transfer-pathway state|Electron-transfer-pathway states]] ::::» MitoPedia: '''[[S-pathway control state]]'''
    1 KB (190 words) - 10:02, 3 June 2020
  • Pathway control ratio
    ...OS]], [[Electron transfer pathway]]), numerous [[Electron-transfer-pathway state]]s are possible. ...h variable [[N]]-linked injuries are studied. In contrast, the [[reference state]], ''Z'', is strictly defined for [[flux control efficiency]].
    1 KB (206 words) - 12:20, 25 November 2020
  • NS-S pathway control efficiency
    ..., S(Rot) or S. Then the NS-S pathway control efficiency in the ET-coupling state is ...pe N substrate combination. Experimentally rotenone Rot is added to the NS-state. The reversed protocol, adding N-substrates to a S-pathway control backgrou
    2 KB (288 words) - 18:30, 1 January 2021
  • SUIT-003 Ce1;ce2SD;ce3U;ce4Rot;ce5Ama
    ! Respiratory state ...f respiration. Mitochondria of dead cells (dce) without substrate are in a state of ROX.
    1 KB (216 words) - 09:44, 3 June 2020
  • Hyphenation
    ...nt), but if the compound adjective follows the term (measurement at steady state), hyphenation does not add any information and should be avoided. Find more ...ate]] (''NOT'' 'Coupling control state' - it is not 'coupling of a control state')
    4 KB (469 words) - 02:31, 23 January 2023
  • NADH electron transfer-pathway state
    ...alonic acid]]). In the N-pathway control state [[Electron-transfer-pathway state|ET pathway level 4]] is active. |info=[[Electron-transfer-pathway state]], [[Gnaiger 2020 BEC MitoPathways]]
    3 KB (409 words) - 08:06, 25 November 2023
  • Pathway and coupling control states
    ...nd ''E'' as subscripts attached to the abbreviation of the pathway control state. ::::* [[N-pathway control state]] N<sub>''L''</sub>, N<sub>''P''</sub>, N<sub>''E''</sub>
    2 KB (340 words) - 16:40, 6 July 2023
  • Complex II-linked substrate state
    |description=''See'' '''[[S-pathway control state]] (previous: CII-linked) |mitopedia concept=Respiratory state, SUIT state, Find
    227 bytes (26 words) - 07:06, 29 May 2018
  • NS-pathway control state
    ...rations by addition of [[NADH]]-generating substrates ([[N-pathway control state]] in combination with [[succinate]] ([[Succinate pathway]]; S). Whereas NS |info=[[Electron-transfer-pathway state]], [[Gnaiger 2020 BEC MitoPathways]], [[Gnaiger_2009_Int J Biochem Cell Bio
    4 KB (604 words) - 08:32, 25 November 2023
  • FNS
    ...ed pathway control) in combination with [[succinate]] ([[S-pathway control state]]; S- or CII-linked) and one or several fatty acids, which are supplied to |info=[[Electron-transfer-pathway state]], [[Gnaiger 2020 BEC MitoPathways]]
    3 KB (403 words) - 19:58, 1 January 2021
  • SUIT-003 Ce1;ce1SD;ce2Omy;ce3U-
    ! Respiratory state | Dead cells (dce) without substrate are in a state of ROX.
    2 KB (325 words) - 12:35, 25 November 2020
  • SUIT-003 Ce1;ce2SD;ce3Omy;ce4U-
    ! Respiratory state | Dead cells (dce) without substrate are in a state of ROX.
    2 KB (325 words) - 12:33, 25 November 2020
  • Cardoso 2022 Q10 Hamburg
    |title=Cardoso LHD, Donnelly C, Komlodi T, Gnaiger E (2022) Coenzyme Q redox state and respiration in permeabilized HEK 293T cells: coupling and pathway contr ...rial inner membrane. ET capacity is measured in the noncoupled respiratory state after application of uncouplers, whereas LEAK respiration is assessed in th
    4 KB (580 words) - 18:34, 5 May 2022
  • Q-junction
    ...upstream, provides the rationale for defining [[Electron-transfer-pathway state]]s and [[categories of SUIT protocols]].
    2 KB (291 words) - 19:31, 25 August 2023
  • SUIT-020 O2 mt D032
    ...f the ATP synthase. Since higher concentrations of Omy can decrease the ET state induced upon addition of uncoupler, the required concentration of Omy has t ...tate| S]] and [[NADH Electron transfer-pathway state| N-]] pathway control state.
    4 KB (636 words) - 15:11, 17 September 2020
  • N/S pathway control ratio
    ...s. The S-pathway control state may be selected preferentially as reference state, if mitochondria are studied with respect to N-pathway injuries. ...in the OXPHOS-state, but N<sub>''E''</sub>/S<sub>''E''</sub> ~ 2 in the ET-state (high [[E-P excess capacity |''E-P'' excess capacity]] specifically for the
    2 KB (300 words) - 19:14, 30 December 2020
  • Categories of SUIT protocols
    ...of substrates and inhibitors which define the [[Electron-transfer-pathway state]]s. The [[N-pathway control |N-type substrates]] are listed in parentheses, ...Y(X)'''- In the SUIT general protocols Y makes reference to the ET-pathway state and X to the combination os substrates added for the corresponding pathway.
    5 KB (673 words) - 16:25, 3 June 2020
  • Sharma 2015 Proc Natl Acad Sci U S A
    ...ns, we propose that this short-circuit is effectively prevented by a redox-state-dependent organization of water molecules within the protein structure that
    2 KB (284 words) - 20:06, 27 January 2024
  • Komlodi 2017 MiPschool Obergurgl
    ...b> production in the LEAK state and O<sub>2</sub> consumption in the OXHOS state establishes the concept that electron pressure generated by the linear S- a |topics=Flux control, Inhibitor, Q-junction effect, Redox state, Substrate
    5 KB (694 words) - 18:54, 10 January 2022
  • Kaila 2014 Proc Natl Acad Sci U S A
    ...we constructed a symmetry-related structure of a possible alternate-access state. In molecular dynamics simulations, we find the resulting structural change
    2 KB (327 words) - 19:56, 27 January 2024
  • S/NS pathway control ratio
    ...ing N-type substrates to a [[S-pathway control state]] as the [[background state]] does not provide a valid estimation of S-linked respiration with succinat
    1 KB (163 words) - 18:28, 1 January 2021
  • Vartak 2013 Protein Cell
    ...iffused in the inner mitochondrial membrane has been replaced by the solid state supercomplex model wherein the respiratory complexes associate with each ot
    2 KB (218 words) - 16:01, 5 November 2023
  • SUIT protocol names
    ...y listing in parentheses the substrates applied in the [[N-pathway control state]]s, again independent of the sequence of titrations, e.g. NS(GM), NS(PM), F ...mma). The [[Marks in DatLab |Marks]] define the section of a [[respiratory state]] in the SUIT protocol. The [[Mark names in DatLab |Mark name]] contains th
    2 KB (267 words) - 09:59, 3 June 2020
  • SUIT-031
    ...are designed to measure simultaneously O<sub>2</sub> flux and the Q-redox state in isolated mitochondria and permeabilized cells. ...t D072]] simultaneous determination of O<sub>2</sub> flux and the Q-redox state in isolated mitochondria and cells permeabilized previously to addition to
    4 KB (623 words) - 17:57, 13 December 2023
  • SUIT-039 O2 mt D092
    ...er electron transfer pathways are also analyzed in OXPHOS (FN, FNS) and ET-state (FNS, S). :::+ The protocol provides information on F-pathway in OXPHOS state with palmitoylcarnitine, a long-chain acylcarnitine commonly found ''in viv
    3 KB (387 words) - 11:21, 14 April 2023
  • SUIT-039 O2 pfi D093
    ...er electron transfer pathways are also analyzed in OXPHOS (FN, FNS) and ET-state (FNS, S). :::+ The protocol provides information on F-pathway in OXPHOS state with palmitoylcarnitine, a long-chain acylcarnitine commonly found ''in viv
    3 KB (387 words) - 12:30, 14 April 2023
  • PGMS-pathway control state
    '''MitoPathway control state:''' [[NS|NS-pathway control state]] ::::» [[NS-pathway control state]]
    2 KB (284 words) - 18:29, 17 March 2022
  • Schinagl 2016 PLoS One
    ...r W (2016) Adapting high-resolution respirometry to glucose-limited steady state mycelium of the filamentous fungus ''Penicillium ochrochloron'': method dev ...lium and a direct transfer of a broth sample into the respirometer. Steady state respiration was 29% below its maximum respiratory capacity. Additionally to
    3 KB (386 words) - 15:46, 14 October 2023
  • Cardoso 2022a EBEC
    ...of the Q-junction, respectively, impacts the relation between the Q redox state and O<sub>2</sub> flux in opposite directions. Therefore, our aim was to ch ...he NextGen-O2k with Q-Module to measure O<sub>2</sub> flux and the Q redox state simultaneously, using CoQ<sub>2</sub> as a probe [3]. Cryopreserved HEK 293
    4 KB (519 words) - 14:25, 23 August 2022
  • SUIT-021 O2 mt D035
    ...tate| S]] and [[NADH Electron transfer-pathway state| N-]] pathway control state. ...s to be determined. Higher concentrations of oligomycin may inhibit the ET state.
    3 KB (420 words) - 09:20, 18 September 2020
  • Komlodi 2018 AussieMit
    ...O<sub>2</sub> flux, H<sub>2</sub>O<sub>2</sub> flux, and coenzyme Q redox state. AussieMit 2018 Melbourne AU. ...an altered Q redox state. We analyzed the relationship between the Q redox state, H<sub>2</sub>O<sub>2</sub> and O<sub>2</sub> fluxes with fuel substrates p
    3 KB (517 words) - 18:56, 10 January 2022
  • Verkhovsky 1996 Nature
    ...coli leads to a corresponding decrease in the enzyme's operational steady-state affinity for O2. This demonstrates directly that fast electron transfer bet
    2 KB (247 words) - 21:39, 24 September 2021
  • Komlodi 2021 MitoFit Q
    ...Rich PR, Gnaiger E (2021) Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria. https://doi.org/10.26124/mitofit: ...omlodi_2021_MitoFit_Q.pdf Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria]
    5 KB (767 words) - 08:41, 8 January 2023
  • Cardoso 2022 ESCI Bari
    ...getic fingerprinting with coupling and pathway control of coenzyme Q redox state and respiration in permeabilized HEK 293T cells. 56<sup>th</sup> Annual Sci We characterised the Q redox state in pathway and coupling control using the Oroboros NextGen-O2k with the ele
    4 KB (520 words) - 14:41, 30 May 2022
  • SUIT-028
    ! Respiratory state ...ate with type N substrates, N<sub>''L''</sub>: Non-phosphorylating resting state with NADH-linked (type N) substrates pyruvate&glutamate&malate (PGM; withou
    4 KB (574 words) - 16:13, 14 April 2020
  • SUIT-021
    ...support NADH-linked respiration. Oligomycin (Omy) is used to induce a LEAK state of respiration via the inhibition of the ATP synthase. Since higher concent ...sed [[Mitochondrial membrane potential|mt-membrane potential]] in the LEAK state.
    5 KB (697 words) - 15:58, 8 June 2020
  • Succinate pathway
    ...that supports succinate-linked respiration (succinate-induced respiratory state; previously used nomenclature: CII-linked respiration; SRot; see [[Gnaiger The S-pathway control state is usually induced in mt-preparations by addition of succinate&rotenone. In
    8 KB (1,053 words) - 08:04, 30 March 2023
  • Electron-transfer-pathway state
    |abbr=''ET-pathway state'' ...state]]s. [[Coupling-control state]]s require [[Electron-transfer-pathway state|ET-pathway competent states]], including oxygen supply. [[Categories of SUI
    15 KB (1,913 words) - 19:27, 25 August 2023
  • SUIT-020
    ...f the ATP synthase. Since higher concentrations of Omy can decrease the ET state induced upon addition of uncoupler, the required concentration of Omy has t ...sed [[Mitochondrial membrane potential|mt-membrane potential]] in the LEAK state.
    5 KB (756 words) - 15:03, 17 September 2020
  • SUIT-021 Fluo mt D036
    ...f the ATP synthase. Since higher concentrations of Omy can decrease the ET state induced upon addition of uncoupler, the required concentration of Omy has t ...sed [[Mitochondrial membrane potential|mt-membrane potential]] in the LEAK state.
    6 KB (834 words) - 14:07, 6 September 2021
  • State 3
    ...ate]] of respiration, whereas the cytochromes are in a more oxidized redox state. |mitopedia concept=Respiratory state, Find
    3 KB (449 words) - 18:46, 1 January 2021
  • Chicco 2022 Abstract Bioblast
    ...(NS > S). However, in some types of mitochondria, rotenone added in the NS-state elicits a paradoxical increase in ''J''<sub>O<sub>2</sub></sub>, revealing ::::# Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA - [email protected]
    4 KB (625 words) - 08:33, 28 July 2022
  • SUIT-004
    ...y_state|N]], [[NS-pathway control state| NS]], [[Succinate pathway control state| S]]). SUIT-004 can be extended with the CIV assay module. ...n| ''P'']]-[[ET capacity| ''E'']]) with N substrates ([[PM-pathway control state|PM]]).
    2 KB (293 words) - 23:36, 12 April 2021
  • SUIT-009 AmR mt D021
    ...in the LEAK state. Pyruvate (P) supports [[NADH Electron transfer-pathway state|NADH-pathway (N)]], and usually in the presence of ADP it does not increase ...s protocol is designed to evaluate RET in the S-linked pathway in the LEAK state, which is decreased by ADP due to reduction of the mt-membrane potential.
    5 KB (681 words) - 00:11, 13 April 2021
  • Komlodi 2022 Q10 Hamburg
    ...s: Continuous monitoring of pull and push control of respiration and redox state of the Q-mimetic CoQ<sub>2</sub>. Q10 Hamburg. ...mplemented into the Oroboros NextGen-O2k to monitor continuously the redox state of CoQ2 added as a Q-mimetic simultaneously with O2 consumption (Komlódi e
    4 KB (559 words) - 18:39, 5 May 2022
  • SUIT-012 O2 mt D027
    ...without the involvement of the [[complex II]] ([[Succinate pathway control state| S-pathway]]). It can be useful to understand the contribution and the acti ...pathway state| N-pathway]] is lower and of the [[Succinate pathway control state| S-pathway]] is higher with GM compared to PM (GMP is inhibited by the CII
    3 KB (397 words) - 00:12, 13 April 2021
  • Bioblast alert 2016
    Let's face it: even the state-of-the-art terminology and the many inconsistent variations are not commonl An even worse mistake: we say ‘[[Complex I&II-linked substrate state |CI<small>&</small>II]]’ (or a previous mistake: ‘CI+II’: ''are the t
    4 KB (529 words) - 09:59, 3 June 2020
  • Mathiyazakan 2023 Antimicrob Agents Chemother
    ...nterpart of the soluble mitochondrial cytochrome c, in a so-called "closed state," in which electrons are translocated from the bcc to the aa3 domain. The s
    2 KB (335 words) - 18:10, 17 September 2023
  • N/NS pathway control ratio
    ...TS competent N-linked substrate combinations) and the [[NS-pathway control state]] (N in combination with succinate). NS indicates respiration with a cockta = List of publications: N and NS pathway control state =
    1 KB (163 words) - 18:27, 1 January 2021
  • SUIT-012
    ...-[[ET capacity| ''E'']]) with NADH-linked substrates ([[PM-pathway control state|PM]] and PGM)''' ...may be relevant in the presence of [[glutamate-anaplerotic pathway control state]]. SUIT-012 can be extended with the CIV assay module.
    4 KB (505 words) - 23:57, 12 April 2021
  • Chance 1961 J Biol Chem-I
    ...n level of pyridine nucleotide than was observed aerobically in state 4. These observations suggest that the presence of adenosine 5’
    3 KB (323 words) - 12:06, 8 November 2016
  • Komlodi 2021 BEC Q
    ...Rich PR, Gnaiger E (2021) Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria. Bioenerg Commun 2021.3. https://d ...same manner as Q at Complexes CI, CII and CIII. The CoQ<sub>2</sub> redox state is monitored amperometrically with the working electrode, which is poised a
    6 KB (810 words) - 16:37, 21 January 2024
  • Komlodi 2018 EBEC2018
    ...f mitochondrial respiration, H<sub>2</sub>O<sub>2</sub> flux and the redox state of the Q-pool. ...Q-pool [1]. We aimed at investigating the relationship between the Q redox state, H<sub>2</sub>O<sub>2</sub> and O<sub>2</sub> fluxes with various fuel subs
    4 KB (592 words) - 19:02, 10 January 2022
  • SUIT-024 O2 ce-pce D056
    ...combinations for N-pathway control state; S or RotS for S-pathway control state.
    2 KB (276 words) - 12:36, 25 November 2020
  • Van den Bergen 1994 Eur J Biochem
    ...ty of the cyanide-resistant pathway. The relation between rate and Q redox state for the external NADH dehydrogenase in potato callus mitochondria was found ...spiration rate is proportional to the redox state of the Q-pool. - ''redox state expressed as QH<sub>2</sub> fraction''
    7 KB (1,023 words) - 09:03, 16 July 2021
  • GMS-pathway control state
    ::::» [[OctPGMSGp pathway control state]] ::::» [[NS-pathway control state]]
    3 KB (378 words) - 18:30, 17 March 2022
  • Cardoso 2022 Abstract Bioblast
    ...nitoring of respiration together with NAD(P)H autofluorescence and Q-redox state [1] provides unique analytical and diagnostic power in the study of mitocho ...Rich PR, Gnaiger E (2021) Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria. https://doi.org/10.26124/bec:2021
    3 KB (463 words) - 08:34, 28 July 2022
  • Liang 2019 Front Microbiol
    ...ectron transfer. Further, the short-lived anionic flavin semiquinone (ASQ) state of b-FAD is essential for electron bifurcation. Nfn homologs are widely dis
    3 KB (404 words) - 00:04, 5 November 2023
  • Additive effect of convergent electron flow
    ...espiratory capacities, N + S, is identical to the capacity measured in the state with combined substrates, NS (CI<small>&</small>II). This condition of comp
    3 KB (428 words) - 15:34, 31 January 2024
  • SUIT-027
    |abbr= [[Malate-anaplerotic pathway control state|Malate anaplerosis]] |info='''A:''' '''[[Malate-anaplerotic pathway control state|Malate anaplerotic pathway]]'''
    3 KB (429 words) - 12:04, 3 June 2020
  • Gnaiger 1998 J Exp Biol
    ...is necessary to prevent a large decrease in oxygen affinity in the active state. Upregulation of oxygen affinity provides a functional explanation of the e ...t from definitions by Chance, Williams 1955) has the meaning of a [[LEAK]] state of respiration, without added adenylates (no ADP and no ATP) in the presenc
    4 KB (588 words) - 16:42, 24 April 2023
  • Briston 2017 Sci Rep
    ...herapies. Here, we have investigated the impact of mitochondrial metabolic state on the probability and consequences of mPTP opening. Isolated mitochondria
    2 KB (324 words) - 12:54, 10 March 2020
  • Szibor 2019 Biochim Biophys Acta Bioenerg
    ...reduces the Q pool almost entirely (>90 %) irrespective of the respiratory state. AOX enhances the forward electron transfer (FET) from CII thereby decreasi |topics=Redox state, Q-junction effect
    3 KB (458 words) - 12:35, 3 April 2021
  • SUIT-009 AmR ce-pce D019
    ...s dramatically. Pyruvate (P) supports the [[NADH Electron transfer-pathway state|NADH-pathway]] and thus the convergent NS-pathway with little further effec ...s protocol is designed to evaluate RET in the S-linked pathway in the LEAK state, which is decreased by ADP due to reduction of the protonmotive force, ''pm
    5 KB (832 words) - 00:10, 13 April 2021
  • SUIT-006
    ...tate appropriately. Since higher concentrations of Omy can decrease the ET state induced upon addition of uncoupler, the required concentration of Omy has t ...tential measurements, choose [[SUIT-006 Fluo mt D034]]. For O2 and Q redox state measurements, choose [[SUIT-006 Q mt D071]] or [[SUIT-006 Q ce-pce D073]].
    8 KB (1,169 words) - 13:08, 13 December 2023
  • Gnaiger 2009 Int J Biochem Cell Biol
    ...te in the matrix as substrates for NS-pathway control. This physiological state is reconsituted in mitochondrial preparations by external NS-substrate supp :::::* MitoPedia:» [[Electron-transfer-pathway state#Terminology: from CI- and CII-linked to N and S]]
    7 KB (975 words) - 13:46, 1 May 2024
  • Q-pools
    ...lision model) and Q tightly bound to supercomplexes according to the solid-state model. The two models describe the extremes in a continuum of homogenous or ...<sub>hom</sub> || homogenous pool of ETS-reactive Q according to the fluid-state model (random-collision model) || || 1, 4, 5
    5 KB (698 words) - 21:19, 3 April 2021
  • SUIT-024
    ...hich leads to an overestimation of LEAK respiration, when comparing [[LEAK state without adenylates|''L''(n)]] and [[LEAK respiration|''L''(Omy)]]. Tissue h ...ther N-pathway substrate combinations; S or RotS for the S-pathway control state.
    3 KB (400 words) - 12:36, 25 November 2020
  • Fato 2009 Biochim Biophys Acta
    ...iacetate. ROS production by Complex I is strictly related to its inhibited state. Our results indicate that different Complex I inhibitors can be grouped in
    2 KB (325 words) - 13:22, 30 November 2018
  • Donnelly 2024 Redox Biol
    ...n isolated mitochondria, myotubes and exercising humans. Performing steady-state respirometry with isolated mitochondria we found that oxygen limitation of |topics=Calcium, mt-Membrane potential, Oxygen kinetics, Redox state
    3 KB (366 words) - 13:55, 1 May 2024
  • Muller 2008 Biochem J
    ...ations of succinate and is thought not to occur when NAD is in the reduced state. However, very few studies have examined the rates of superoxide production
    3 KB (401 words) - 17:48, 16 January 2021
  • Cogliati 2021 Biochem Soc Trans
    ...explore how they modulate the ETC organization according to the metabolic state. Since the field is rapidly growing, we also comment on the experimental te
    2 KB (269 words) - 16:55, 8 October 2023
  • SUIT-003 O2 ce D061
    ...the SUIT-003 O2 ce D061 protocol allows evaluating the [[coupling control state |coupling control]] of living cells. Respiratory capacities are tested in a
    4 KB (515 words) - 12:36, 25 November 2020
  • SUIT-009
    ...n in the LEAK state. Pyruvate (P) promotes[[NADH Electron transfer-pathway state|NADH-pathway (N)]], and usually in the presence of ADP, H<sub>2</sub>O<sub ...ub>2</sub>O<sub>2</sub> flux on the mt-membrane potantial on the N-control state in isolated mitochondria, tissue homogenate and permeabilized cells (alread
    6 KB (864 words) - 23:56, 12 April 2021
  • Donnelly 2024 EU-METAHEART MC2 Meeting
    ...ects on oxidative phosphorylation, mitochondrial membrane potential, redox state of coenzyme Q, and calcium uptake. EU-METAHEART MC2 Meeting 2024 Antalya TR ...<sub>2</sub> levels in studies of isolated mitochondria. Performing steady-state respirometry with isolated mouse cardiac mitochondria [2] we found that oxy
    2 KB (328 words) - 15:53, 13 March 2024
  • SUIT-020 Fluo mt D033
    ...sed [[Mitochondrial membrane potential|mt-membrane potential]] in the LEAK state. ...tate| S]] and [[NADH Electron transfer-pathway state| N-]] pathway control state.
    5 KB (655 words) - 08:41, 30 September 2020
  • Oliveira Pinto 2013 Abstract IOC75
    |topics=Aerobic glycolysis, Redox state
    3 KB (359 words) - 15:14, 20 October 2017
  • SUIT-025
    ...ion_pathway_control_state|F]], F(N), [[FN]] and [[FNS]] pathways in OXPHOS state can be evaluated by using this SUIT protocol. :::+ The protocol provides information on F-pathway in OXPHOS state. The low concentration of malate used in this protocol, typically 0.1 mM, d
    3 KB (407 words) - 13:24, 5 June 2019
  • Sharpley 2006 J Biol Chem
    ...n2+ inhibition of complex I is high (10-50 microm, depending on the enzyme state); therefore, complex I is unlikely to be a major site for zinc inhibition o
    2 KB (327 words) - 04:53, 15 October 2023
  • Pichaud 2012 Comp Biochem Physiol A Mol Integr Physiol
    ...em, and suggested that the AOX activity is triggered not only by the redox state of the cell but also by the type of substrates provided to mitochondria.
    2 KB (280 words) - 11:04, 23 June 2022
  • Vesga 2021 Med Chem Res
    ...en consumption in the LEAK state (10 µM, 24 h), as well as the increase in state 4 in the mitochondrial bioenergetics. In all cases, molecular hybrids incre
    2 KB (273 words) - 09:31, 9 November 2023
  • Doerrier 2017 MiPschool C2
    ...ol and the subsequent linear sequence of pathway control in the ET-pathway state. RP2) RP2 has a focus on OXPHOS capacity of fatty acid oxidation (F-pathway
    5 KB (706 words) - 12:00, 27 May 2019
  • Sharma 2013 Proc Natl Acad Sci U S A
    ...V, Karlin KD, Wikström M (2013) Computational study of the activated O(H) state in the catalytic mechanism of cytochrome ''c'' oxidase. Proc Natl Acad Sci ...theory calculations, to be substantially higher in the O(H) state than in state O. Our calculations also suggest that the neutral radical form of the cross
    2 KB (331 words) - 19:46, 27 January 2024
  • Templage:Keywords-MitoPedia BEC 2020.2
    ...b>2</sub></sub> || 1 || P»/O<sub>2</sub> ratio measured in any respiratory state; Section 1.6; Eq. 3.4 | coupling control state || [[Coupling control state]] || CCS || - || Section 2.4.1
    15 KB (2,142 words) - 23:29, 6 February 2021
  • SUIT-019
    ...rylation|OXPHOS state]], and [[FN]]—[[FNS]]—[[S]] in the [[ET capacity| ET state]]. ...he protocol provides information on [[Fatty acid oxidation pathway control state| F-pathway]] (in presence of palmitoylcarnitine, and palmitoylcarnitine&oct
    3 KB (412 words) - 12:33, 25 November 2020
  • Sjoevall 2010 Crit Care
    ...n septic plasma exhibited increased basal non-phosphorylating respiration (state 4) compared to controls and to platelets suspended in PBS glucose. In paral
    3 KB (486 words) - 13:22, 27 December 2021
  • ET capacity
    ...e addition of defined fuel substrates to establish an ET-pathway competent state. » [[#Why ET capacity, why not State 3u.3F | '''MiPNet article''']]
    11 KB (1,488 words) - 20:30, 19 March 2022
  • Gnaiger 2018 MiPschool Tromso A1
    ...s]]. Complementary to [[pathway control state]]s (PCS), [[coupling control state]]s (CCS: ET, OXPHOS, LEAK) are defined in mt-preparations, and the correspo ...basis, the classical [[respiratory acceptor control ratio]] (RCR = State 3/State 4 respiration) has to be replaced by the biochemical coupling efficiency, d
    10 KB (1,441 words) - 23:46, 25 January 2021
  • Jensen 2007 Biochimica et Biophys Acta (BBA) - Bioenergetics
    ...y transfer, Light harvesting, Photosynthesis, Red chlorophylls Regulation, State transitions
    2 KB (311 words) - 17:53, 4 March 2020
  • Hoppel 2021 Front Physiol
    .... There were inverse correlations between race time and N-linked substrate state PRE-POST, and changes in CK and LDH levels were significantly related to PL
    4 KB (517 words) - 15:51, 7 June 2022
  • Duicu 2012 Rev Med Chir Soc Med Nat Iasi
    ...ansport system (ET-pathway); CII_P, 302.26 +/- 50.16 (CII dependent OXPHOS state obtained after the addition of a CI inhibitor rotenone, with the subsequent
    2 KB (325 words) - 11:42, 23 January 2019
  • Jumbo-Lucioni 2012 BMC Genomics
    ...3 SNPs can explain 31, 13, and 18% of the phenotypic variation in state 3, state 4, and P:O ratio, respectively. Most of the genes tagged by the SNPs are in
    3 KB (412 words) - 12:21, 9 August 2019
  • Malate
    ...te| FAO-pathway]]. In the presence of [[Malate-anaplerotic pathway control state|anaplerotic pathways]] (''e.g.'', [[Malic enzyme|mitochondrial malic enzyme
    4 KB (585 words) - 19:57, 5 February 2022
  • SUIT-037 O2 mt D090
    :::+ The protocol provides information on F-pathway in OXPHOS state. The low concentration of malate used in this protocol, typically 0.1 mM, d :::+ F-pathway (3Pal-2M.1) can be compared to FN-pathway (5P) in OXPHOS state.
    3 KB (485 words) - 11:21, 14 April 2023
  • SUIT-011
    ...y capacity ([[Oxidative phosphorylation|OXPHOS]] with [[NS-pathway control state|NS substrates]]) and coupling/pathway control''' ...ET state ([[NS-pathway control state|NS]] and [[Succinate pathway control state|S]]). SUIT-011 can be extended with the CIV assay module.
    6 KB (951 words) - 15:35, 8 June 2020
  • Doerrier 2017 Abstract MitoEAGLE Barcelona
    ...ol and the subsequent linear sequence of pathway control in the ET-pathway state. RP2) RP2 has a focus on OXPHOS capacity of fatty acid oxidation (F-pathway
    6 KB (754 words) - 12:00, 27 May 2019
  • Wessels 2019 Obesity (Silver Spring)
    |abstract=The study aimed to investigate how obesity and glycemic state affect mitochondrial respiration and ATP-generating pathways in mature huma ...In both depots, the respiratory capacity was not affected by the glycemic state. A positive correlation between BMI and adipocyte lactate release was measu
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  • Ojuka 2015 Abstract MiPschool Cape Town 2015
    carnitine or malate increase State 2 respiration (oxygen consumption
    3 KB (438 words) - 16:16, 26 March 2018
  • SUIT-025 O2 mt D057
    :::+ The protocol provides information on F-pathway in OXPHOS state. The low concentration of malate used in this protocol, typically 0.1 mM, d :::+ F-pathway (3Oct-2M.1) can be compared to FN-pathway (5P) in OXPHOS state.
    2 KB (345 words) - 10:29, 18 September 2020
  • Jarmuszkiewicz 2023 Front Biosci (Landmark Ed)
    ...uction. We have proposed that the level of reduction (the endogenous redox state) of mtQ may be a useful indirect marker to assess total mtROS formation. A ...ctrode [28,129] will contribute to the widespread measurement of the redox state of mtQ in isolated respiring mitochondria."
    3 KB (422 words) - 11:58, 27 March 2023
  • Pichaud 2013 Abstract MiP2013
    |topics=ADP, Flux control, Inhibitor, Oxygen kinetics, Redox state, Substrate, Temperature, Uncoupler
    2 KB (323 words) - 15:39, 13 November 2017
  • Flux control efficiency
    ...h (stimulated or un-inhibited) flux; ''Y<sub>X</sub>'' is the [[background state]] at low flux, upon which ''X'' acts. ...x from ''Y<sub>X</sub>'' to ''Z<sub>X</sub>'' normalized for the reference state ''Z<sub>X</sub>''.
    8 KB (1,272 words) - 18:27, 1 January 2021
  • SUIT-006 O2 mt D022
    ...''see'' [[MitoPedia: Sample preparations]]) at [[Succinate pathway control state]].
    3 KB (368 words) - 23:53, 12 April 2021
  • Lemieux 2011 Abstract Bordeaux
    ...lation. Under these conditions, the increase of respiration in the OXPHOS state at constant ET capacity indicates a mitochondrial dysfunction after cold pr ...ux control ratios by internal normalization for oxygen flux in a reference state [2].
    6 KB (874 words) - 18:21, 10 January 2022
  • Du 2016 Aquat Toxicol
    ...mplies a heritable change in OxPhos function. The observation that LEAK, E-State, Complex I and Complex II were different in laboratory bred versus field-ca
    3 KB (402 words) - 17:52, 9 November 2017
  • Selivanov 2011 PLoS Comput Biol
    ...lex III, remains valid for the whole RC. The conditions for switching to a state with a high content of free radicals in Complex III were predicted based on |topics=mt-Membrane potential, Redox state
    3 KB (364 words) - 17:59, 29 February 2020
  • SUIT-036 O2 mt D089
    :::+ The protocol provides information on F-pathway in OXPHOS state. The low concentration of malate used in this protocol, typically 0.1 mM, d :::+ F-pathway (3Pal-2M.1) can be compared to FN-pathway (5P) in OXPHOS state.
    3 KB (450 words) - 11:20, 14 April 2023
  • SUIT protocol library
    ...Define pathway states |Define substrates and inhibitors]] for each pathway state. ...pathway control state]], [[S-pathway control state]], [[NS-pathway control state]]). Titrations may performed in a single step, or in multiple steps for seq
    5 KB (721 words) - 15:01, 8 June 2020
  • Gnaiger Abstract MiP2010 2-01
    ...ondrial respiratory capacity of fibroblasts in vivo. The coupled reference state and reinterpretation of the uncoupling control ratio. Mitochondr Physiol Ne
    8 KB (1,121 words) - 19:16, 10 January 2022
  • Gnaiger 2017 Abstract MitoEAGLE Barcelona
    ...ADH&succinate (NS) pathway, and azide titrations in the NS-pathway control state or single step of CIV. As&TM, Ascorbate&TMPD. From Ref [8].
    7 KB (927 words) - 18:53, 10 January 2022
  • SUIT-031 O2 mt D075
    |info='''A''' to analyse O<sub>2</sub> flux in the NS- pathway control state on isolated mitochondria- '''[[SUIT-031]]''' ...n the N-pathway and contribution of G-, S-, Oct- and Gp-pathways in the ET state for isolated mitochondria, tissue homogenate and cells permeabilized before
    3 KB (355 words) - 11:56, 2 December 2021
  • Muller 2013 Exp Neurol
    ...maximum level of ∆Ψm induced by succinate in synaptosomes in a depolarized state. Similarly, insulin decreased ROS production in neuronal cultures. In mitoc
    3 KB (378 words) - 17:05, 27 March 2018
  • SUIT-029 O2 mt D066
    :::::::+ Evaluation of ET-state with NADH-linked substrates allows to calculate ET-coupling efficiency (1-' ...ditive effect of convergent flux through NADH-linked respiration in the ET-state is evaluated (5G).
    4 KB (508 words) - 11:50, 15 March 2024
  • Goetz 2000 J Neural Transm (Vienna)
    ...R, Dirr A, Janetzky B, Kuhn W, Riederer P, Gerlach M (2000) Altered redox state of platelet coenzyme Q<sub>10</sub> in Parkinson's disease. J Neural Transm ...transport which might be reflected by the platelet CoQQ<sub>10</sub> redox state.
    2 KB (364 words) - 12:39, 3 April 2021
  • SUIT-031 O2 ce-pce D079
    |info='''A''' to analyse O<sub>2</sub> flux in the NS- pathway control state in permeabilized cells- '''[[SUIT-031]]''' ...n the N-pathway and contribution of G-, S-, Oct- and Gp-pathways in the ET state for isolated mitochondria, tissue homogenate and cells permeabilized before
    3 KB (361 words) - 12:15, 2 December 2021
  • Wollenman 2017 PLOS ONE
    ...f 16%, 26%, and 35% for the leak state, ADP-simulated state, and uncoupled state, respectively, relative to rates using B1. The common feature distinguishin ...way control state |Pyruvate&malate, PM]]: [[NADH electron transfer-pathway state |N-pathway]]
    10 KB (1,407 words) - 19:20, 9 February 2022
  • SUIT-011 O2 pfi D024
    ...b>''P''</sub>. SUIT-004 should be chosen for the additive effect in the ET-state. ...state in[[NS-pathway control state| NS-]] and [[Succinate pathway control state| S-pathways]] can be assessed.
    5 KB (784 words) - 11:18, 17 September 2020
  • Lenaz 2007 Am J Physiol Cell Physiol
    ...ansfer in the mitochondrial respiratory chain: random collisions vs. solid state electron channeling. Am J Physiol Cell Physiol 292:C1221-39. doi: 10.1152/a
    2 KB (246 words) - 12:50, 25 March 2021
  • Oliveira 2011 Insect Biochem Mol Biol
    ...er expression levels of several glycolytic enzyme genes. Furthermore, when State 3 respiration was reduced in S females by silencing expression of the adeni
    2 KB (231 words) - 10:03, 9 November 2016
  • Gnaiger 2011 Abstract-MonteVerita
    ...ation increases linearly with respiratory capacity controlled by metabolic state, from 0.2 to 1.6 µM determined by [[high-resolution respirometry]]. O<sub>
    3 KB (393 words) - 18:20, 10 January 2022
  • SUIT-015
    ...ration#The_LEAK_state |LEAK state]] and [[Oxidative phosphorylation|OXPHOS state]]''' ...osphorylation|OXPHOS state]] and of [[FNS]] and [[S]] in [[ET capacity| ET state]] can be evaluated. SUIT-015 can be extended with the CIV assay module.
    3 KB (393 words) - 15:21, 8 June 2020
  • SUIT-014
    ...and ET state ([[NS-pathway control state|NS]], [[Succinate pathway control state|S]]) is also evaluated, covering the contribution of two pathways which are ...b>''P''</sub>. SUIT-004 should be chosen for the additive effect in the ET-state.
    4 KB (634 words) - 15:21, 8 June 2020
  • Makrecka-Kuka 2015 Biomolecules
    ...hest in the succinate-linked LEAK state, reduced with [[NS-pathway control state |NS-linked convergent electron flow]] and in mitochondria respiring at OXPH
    4 KB (484 words) - 19:56, 7 January 2024
  • SUIT-008
    |info='''A: Additivity between the N- and [[Succinate pathway control state| S-pathway]] in the Q-junction''' ...NADH_Electron_transfer-pathway_state| N-]] and [[Succinate pathway control state| S-pathway]] in the [[Q-junction]], providing a physiologically relevant es
    4 KB (668 words) - 09:41, 30 November 2023
  • Gnaiger 1998 Biochim Biophys Acta
    ...ncy, ''J''max/''p''<sub>50</sub>, increased from the resting to the active state, despite the decrease of oxygen affinity, 1/''p''<sub>50</sub>. Consequentl ::::* [[State 2]] in this publication has the meaning of a [[LEAK]] state of respiration, without added adenylates (no ADP and no ATP) in the presenc
    4 KB (505 words) - 16:27, 24 April 2023
  • Toleikis 2020 Cells
    ...osine diphosphate (ADP)/adenosine triphosphate (ATP) carrier (M-state to C-state, condensed to orthodox mitochondria) may affect the oxidative phosphorylati
    2 KB (266 words) - 17:03, 5 October 2023
  • SUIT-016
    ...ration#The_LEAK_state |LEAK state]] and [[Oxidative phosphorylation|OXPHOS state]]''' ...] in [[LEAK respiration#The_LEAK_state |LEAK state]] and [[ET capacity| ET state]] is evaluated.
    4 KB (543 words) - 15:19, 8 June 2020
  • Pallag 2022 Int J Mol Sci
    ...of oxygen consumption, membrane potential, NADH, and the ubiquinone redox state were correlated to ProDH activity and F<sub>1</sub>F<sub>O</sub>-ATPase dir |topics=mt-Membrane potential, Redox state
    3 KB (409 words) - 15:12, 9 December 2022
  • Residual oxygen consumption
    ...hondrial respiration is frequently corrected for ''Rox'' as the [[baseline state]]. Then, total [[ROUTINE]], [[LEAK respiration]], [[OXPHOS]] or [[Electron ...BEC MitoPathways]]), the [[REN]] state was not distinguished from the ROX state. However, in novel applications (Q-Module and NADH-Module), a distinction o
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  • LEAK state with ATP
    ...0 Proc Natl Acad Sci U S A |Gnaiger et al 2000]]). Respiration in the LEAK state with ATP, ''L''(T), is distinguished from ''L''(n) and ''L''(Omy). == The LEAK state of respiration: towards a concept-linked terminology of respiratory states
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  • Komlodi 2017 Abstract MITOEAGLE Barcelona
    ...ADP added to S(-Rot) inhibited oxygen consumption with respect to the LEAK state at low succinate concentration in guinea pig brain and heart, but even at h ...ndogenously produced oxaloacetate (Oa), which is particulaly pronounced in state S(-Rot) [4]. However, exogenously added Oa inhibited SDH measured in brain
    6 KB (912 words) - 18:51, 10 January 2022
  • Srivastava 2016 Clin Transl Med
    ...ys, and through their activation, NAD(+) directly links the cellular redox state with signaling and transcriptional events. NAD(+) levels decline with mitoc
    3 KB (344 words) - 17:37, 5 October 2023
  • McCommis Kyle S
    |state=Missouri (MO)
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  • Elasticity
    ...ken at the metabolite concentrations found in the pathway in the metabolic state of interest. It can be obtained directly as the slope of the logarithm of t
    1 KB (151 words) - 11:53, 25 November 2020
  • Pesta 2012 Methods Mol Biol
    ...[[dyscoupling]] is evaluated as a mitochondrial defect. The [[noncoupled]] state of maximum respiration is experimentally induced by titration of establishe
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  • SUIT-005
    |info='''A:''' when [[Malate-anaplerotic pathway control state |malate-anaplerotic activity]] is zero ...onvergence [[FNS |FNS]] pathways in the [[Oxidative phosphorylation|OXPHOS state]]. [[FNS |FNS]] comprises the most important pathways in many cell types an
    3 KB (424 words) - 14:30, 10 March 2023
  • SUIT-002 O2 pfi D006
    :::+ The protocol provides information on F-pathway in OXPHOS state. The low concentration of malate used in this protocol, typically 0.1 mM, d :::+ F-pathway (3Oct-2M.1) can be compared to FN-pathway (5P) in OXPHOS state.
    3 KB (439 words) - 18:44, 5 March 2024
  • Bialas 2018 Int J Chron Obstruct Pulmon Dis
    ...sub>=0.04. The study group also demonstrated lowered respiration in the ET-state (normalized for protein content): 12.31 (4.84) vs 16.48 (1.72) (pmol O<sub>
    3 KB (430 words) - 00:24, 16 February 2020
  • SUIT-004 O2 pfi D010
    ...ity| ''E'']]) with NADPH-linked substrate substrates ([[PM-pathway control state|PM]]). ...y_state|N]], [[NS-pathway control state| NS]], [[Succinate pathway control state| S]]).
    3 KB (354 words) - 23:49, 12 April 2021
  • SUIT-018 AmR mt D040
    ...lso advisable to either detect H<sub>2</sub>O<sub>2</sub> flux at the same state for high (tissue hyperoxia; [O<sub>2</sub>]> ~100-110 µM) and low (tissue ...end of the protocol to study the effect of oxygen concentration in the ROX state (in the presence of Ama) both on the O<sub>2</sub> and H<sub>2</sub>O<sub>2
    4 KB (625 words) - 12:09, 7 March 2024
  • Vinogradov Andrei D
    Moscow State University :::: Andrei started his scientific career at Moscow State University in the former USSR in 1964. He obtained his postdoctoral trainin
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  • Hall 2013 Biochim Biophys Acta
    ...2]] and [[State 4o]] oxygen flux as well as lowered ADP phosphorylation ([[State 3]]) and mitochondrial ATP synthesis. Polycation-mediated reduction of elec
    3 KB (327 words) - 11:13, 22 November 2023
  • Zuccolotto-dos-Reis 2021 MitoFit ACoAR
    ...oes fresh homogenate (used as a reference for cryopreservation) compare to state-of-the-art mitochondrial preparations of (human) skeletal muscle tissue? Ev
    4 KB (558 words) - 08:43, 8 January 2023
  • Kontro 2016 Thesis
    Statistical analysis showed a significant difference in the LEAK respiration state (P<0.05) and LEAK control ratio (P<0.01) between young and old LCR rats (L: ...R show a decline in their OXPHOS and ET capacity with age, but not in LEAK state respiration.
    3 KB (424 words) - 14:57, 13 November 2017
  • Garcia Geovana S
    São Paulo State University -Jaboticabal campus (FCAV-UNESP); São Paulo State University - São José do Rio Preto campus (IBILCE-UNESP), BR
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  • LEAK respiration
    ...easurement and expression of respiration vary ([[oxygen flux]] in the LEAK state, ''J''<sub>O<sub>2</sub>''L''</sub>, or [[oxygen flow]], ''I''<sub>O<sub>2< ...stem and in mt-preparations supported by an ET-pathway competent substrate state, exemplifed as the NS-pathway (CI<small>&</small>II-linked substrate supply
    12 KB (1,658 words) - 01:03, 31 December 2020
  • SUIT-002
    ...ays) and in [[ET capacity| ET state]] ([[FNSGp]] and [[SGp-pathway control state|SGp]]) can be evaluated by using this SUIT protocol. SUIT-002 can be extend :::+ The protocol provides information on F-pathway in OXPHOS state. The low concentration of malate used in this protocol, typically 0.1 mM, d
    6 KB (809 words) - 18:41, 5 March 2024
  • US MO St Louis McCommis KS
    |state=Missouri (MO)
    378 bytes (54 words) - 09:25, 4 September 2023
  • Dantas Wagner S
    |state=Louisiana (LA)
    354 bytes (43 words) - 08:37, 15 April 2024
  • Chen 2022 Am J Physiol Cell Physiol
    ...contribute to •O2− generation in the respiratory conditions of state 2 and state 4. Black circles show aconitase of the Krebs Cycle that generates NADH and |topics=Redox state
    5 KB (754 words) - 03:39, 11 November 2023
  • Goetzman Eric S
    |state=Pennsylvania (PA)
    332 bytes (38 words) - 17:51, 29 February 2020
  • SUIT-031 Q mt D072
    ...analyse O2 flux and the Q-redox state in the N-,NS- and S- pathway control state on isolated mitochondria- '''[[SUIT-031]]''' ...to be determined if used. Higher concentrations of Omy may inhibit the ET state.
    4 KB (530 words) - 16:17, 13 December 2023
  • Gopalakrishnan 2020 Sci Rep
    ...Ranji M, Eells JT (2020) Photobiomodulation preserves mitochondrial redox state and is retinoprotective in a rodent model of retinitis pigmentosa. Sci Rep ...sham-treated group. PBM protected against the disruption of the oxidation state of the mitochondrial respiratory chain observed in sham-treated animals. Sc
    3 KB (395 words) - 04:44, 4 November 2023
  • Kunz 1994 Anal Biochem
    ...nase reached after addition of 1 mM ADP correlates with the rate of active state respiration with NAD-dependent substrates. Therefore, this fluorimetric met
    2 KB (339 words) - 10:43, 23 January 2019
  • Aid-Vanakova 2019 MiP2019
    ...bstrate, no significant difference was detected. At the same time the leak state without adenylates is higher in Wfs1KO in most muscles with both complex I
    5 KB (679 words) - 09:31, 2 September 2019
  • Du 2015 Aquat Toxicol
    ...exposure and undosed fish show decreased LEAK and increased State 3 and E state.
    2 KB (339 words) - 17:51, 9 November 2017
  • Fatty acid oxidation
    :» [[F-pathway control state]]
    4 KB (596 words) - 09:27, 8 May 2023
  • Reiss 2022 Exp Gerontol
    ...ets and evaluates neuroprotective agents that could improve the functional state of mitochondria in the setting of AD.
    2 KB (290 words) - 15:57, 19 December 2023
  • Enriquez 2014 Mol Syndromol
    | solid model || ↔ || solid state model | random collision model || ↔ || liquid state model
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  • SUIT-019 O2 pfi D045
    ...n the absence of other, potentially interfering pathways, both in the LEAK state and in OXPHOS. ...ays) and in [[ET capacity| ET state]] ([[FNSGp]] and [[SGp-pathway control state|SGp]]) can be evaluated by using this SUIT protocol.
    3 KB (424 words) - 14:38, 17 September 2020
  • Stadlmann 2006 Cell Biochem Biophys
    ...s ([[Permeabilized tissue or cells |pce]]). dce without substrate are in a state of ROX<sub>dce</sub>. ...ected by extracellular succinate and ADP (SD); dce (with intact mt) are in state S<sub>''P'',dce</sub>. ''Limitation'': In the absence of rotenone, S-OXPHOS
    12 KB (1,918 words) - 13:59, 27 December 2021
  • Yuan 2022 Oxid Med Cell Longev
    ...servation. Overnutrition causes nonspecific, persistently low inflammatory state known as metabolic inflammation. This condition contributes to the pathophy
    1 KB (194 words) - 11:04, 22 March 2023
  • SUIT-031 Q ce-pce D074
    ...'A''' to analyse O2 flux and the Q-redox state in the NS- pathway control state on permeabilized cells- '''[[SUIT-031]]''' ...to be determined if used. Higher concentrations of Omy may inhibit the ET state.
    4 KB (519 words) - 17:52, 13 December 2023
  • Edman Sebastian
    |state=
    377 bytes (43 words) - 12:20, 20 June 2023
  • Yoval-Sanchez 2022 Redox Biol
    ...ng its flavin mononucleotide (FMN) cofactor when maintained in the reduced state in conditions of RET both ''in vitro'' and ''in vivo''. Here we investigate
    3 KB (440 words) - 12:07, 5 December 2022
  • SUIT-002 O2 mt D005
    :::+ The protocol provides information on F-pathway in OXPHOS state. The low concentration of malate used in this protocol, typically 0.1 mM, d :::+ F-pathway (3Oct-2M.1) can be compared to FN-pathway (5P) in OXPHOS state.
    4 KB (508 words) - 18:44, 5 March 2024
  • Quintard 2018 Springer, Cham
    |abstract=Our survival state depends on serial metabolic reactions needing energy. Our environmental fee
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  • Michalak 2017 Oxid Med Cell Longev
    ...ols. Decreased ROUTINE respiration (P = 0.007) and oxygen flux in the LEAK state (P = 0.0203) were observed in patients with PD with substantia nigra hypere
    2 KB (313 words) - 23:24, 29 February 2020
  • SUIT-017
    ...osphorylation|OXPHOS state]] and of [[FNS]] and [[S]] in [[ET capacity| ET state]] is evaluated.
    2 KB (325 words) - 23:49, 12 April 2021
  • US PA Pittsburgh Goetzman ES
    |state=Pennsylvania (PA)
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  • SUIT-009 O2 mt D015
    ::: + Cytochrome ''c'' test can be performed in the S-OXPHOS state.
    2 KB (312 words) - 23:50, 12 April 2021
  • SUIT-006 O2 ce-pce D029
    ...alyse the coupling control on permeabilized cells in N(PM) pathway control state- '''[[SUIT-006]]'''
    2 KB (290 words) - 23:58, 12 April 2021
  • Lark DS
    |state=North Carolina (NC)
    207 bytes (25 words) - 15:56, 19 August 2014
  • Hand 2012 Abstract Bioblast
    ...tory Complex I (pyruvate&malate) are used as the fuel source in the OXPHOS state (Fig. 1). Reduced respiration through Complex I is supported by Western blo (1) Department of Biological Sciences, Louisiana State University, Baton Rouge, USA; Email: [email protected]
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  • Hara 2013 Eur J Anaesthesiol
    ...sis group (''P'' = 0.077) and a minor non-significant increase in the LEAK state (''P'' = 0.262) resulting in a statistically significant decreased respirat
    3 KB (428 words) - 13:45, 7 March 2020
  • SUIT-008 O2 ce-pce D025
    ...with NP + SP. SUIT-004 should be chosen for the additive effect in the ET-state. ...'L''- ''P''- ''E'') with NADH linked-substrates (PM) and the control in ET state (N, NS, S)
    3 KB (516 words) - 23:58, 12 April 2021
  • Doerrier 2018 Methods Mol Biol
    ...logical dyscoupling is evaluated as a mitochondrial defect. The noncoupled state of maximum respiration is experimentally induced by titration of establishe
    6 KB (850 words) - 12:27, 5 March 2024
  • Silva 2019 MiPschool Coimbra
    ...of etomoxir on isolated liver mitochondria was also observed in the OXPHOS state, without minor inhibitory effect on FAO. These results suggest that FAO can ...in the presence of 200 µM etomoxir. (A) FCR in OXPHOS-state. (B) FCR in ET-state. The results are expressed as median and interquartile range of 4 independe
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  • SUIT-002 O2 ce-pce D007
    :::+ The protocol provides information on F-pathway in OXPHOS state. The low concentration of malate used in this protocol, typically 0.1 mM, d :::+ F-pathway (3Oct-2M.1) can be compared to FN-pathway (5P) in OXPHOS state.
    4 KB (557 words) - 12:52, 12 April 2023
  • SUIT-026
    ...dded to the chamber). The protocol is focused on [[LEAK respiration|LEAK]] state for the [[S-pathway]] to provide the conditions of high membrane potential ...an Event&Mark for the uncoupler titration (4U) after ADP (3D) to obtain ET-state.
    5 KB (809 words) - 12:39, 24 January 2024
  • SUIT-008 O2 mt D026
    ...'P''-''E'') with NADH linked-substrates (PM) and the pathway control in ET state (N, NS, S pathways).
    3 KB (433 words) - 10:56, 17 September 2020
  • Palasiewicz Karol
    |state=Illinois (IL)
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  • Dang 2014 Plant Cell
    ...in the pgrl1 mutant, resulting in normal biomass productivity under steady state conditions. The lower biomass productivity observed in the pgrl1 mutant in
    2 KB (290 words) - 15:13, 8 August 2023
  • SUIT-002 O2 ce-pce D007a
    :::+ The protocol provides information on F-pathway in OXPHOS state. The low concentration of malate used in this protocol, typically 0.1 mM, d :::+ F-pathway (3Oct-2M.1) can be compared to FN-pathway (5P) in OXPHOS state.
    4 KB (572 words) - 08:25, 12 October 2020
  • Gnaiger 2015 Abstract MiPschool Cape Town 2015 II
    ...o zero in a fully coupled system. Maximal efficiency in the ADP-stimulated state of oxidative phosphorylation (OXPHOS) is, however, not adaptive [1] and is ...g lower the efficiency and contribute to the control of flux in the OXPHOS state. ADP and inorganic phosphate do not equilibrate across the plasma membrane,
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  • US PA Pittsburgh Votyakova TV
    |state=Pennsylvania (PA)
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  • Sidossis LS
    |state=Texas (TX)
    202 bytes (26 words) - 16:52, 18 August 2014
  • SUIT-008 O2 pfi D014
    ...with NP + SP. SUIT-004 should be chosen for the additive effect in the ET-state. ...'L''- ''P''- ''E'') with NADH linked-substrates (PM) and the control in ET state (N, NS, S)
    4 KB (539 words) - 23:48, 12 April 2021
  • Stepanova 2018 J Cereb Blood Flow Metab
    ...lysed and complexome profiling was performed. The effect of conformational state (active/deactive (A/D) transition) of mitochondrial complex I on H<sub>2</s
    3 KB (373 words) - 21:42, 13 April 2022
  • Doerrier 2012 Abstract Bioblast
    |topics=Redox state
    4 KB (548 words) - 11:15, 8 June 2020
  • Bioblast alert 2014
    ...: Respiratory states |MitoPedia]]: [[LEAK respiration |'''Respiratory LEAK state: concept-linked terminology''']] ...Respiratory states |MitoPedia]]: [[ET capacity |'''Why ET-pathway, why not State 3u?''']]
    5 KB (611 words) - 15:14, 8 June 2020
  • Doerrier 2015 Abstract MiP2015
    ...icated in the pathogenesis of many diseases. In particular, the NADH redox state is related to ROS production. Succinate is a substrate of succinate dehydro
    7 KB (948 words) - 18:37, 10 January 2022
  • Doerrier 2015 Abstract MiPschool Greenville 2015
    ...rometer using Amplex Ultrared [2]. In addition, respiration and NADH redox state were measured with a prototype NextGen-O2k, which combines high-resolution ...DP added to S inhibited oxygen consumption by 30% with respect to the LEAK state (SL), which is the so-called “succinate paradox” [3]. This paradox was
    5 KB (714 words) - 18:35, 10 January 2022
  • Miller 2017 PLOS ONE
    ...2017) Mitochondrial respiration in highly aerobic canines in the non-raced state and after a 1600-km sled dog race. PLOS ONE 12:e0174874.
    3 KB (438 words) - 12:52, 27 December 2021
  • The protonmotive force and respiratory control
    ...bbreviations (mtDNA, mt to abbreviate mitochondr*); OXPHOS capacity versus State 3 (discuss saturating ADP/Pi .. concentrations). ::::* '''[[State 2]]'''
    12 KB (1,564 words) - 23:40, 25 January 2021
  • Dhillon RS
    |state=Wisconsin (WI)
    452 bytes (56 words) - 14:04, 13 May 2019
  • Volt 2014 Abstract SECF
    |abstract=Inflammaging involves a persistent pro-inflammatory state coursing with cardiac and energy metabolism alterations. This chronic, subc ...leads us to explore this pathway and its relation with the hyperoxidative state of aging.
    3 KB (374 words) - 08:53, 30 May 2016
  • Iglesias-Gonzalez 2013 J Neurosci Methods
    ...ivity cannot be quantified in the active state ([[State 3]]; [[OXPHOS]] or State ''P''), but uncoupler titrations are required to determine the [[ET-capacit
    3 KB (349 words) - 14:26, 3 June 2020
  • SUIT-006 Q mt D071
    ...b> consumption and the redox state of the Q-pool in S(Rot)-pathway control state in isolated mitochondria- '''[[SUIT-006]]''' ...to be determined if used. Higher concentrations of Omy may inhibit the ET state.
    3 KB (404 words) - 14:23, 18 December 2023
  • Kristal Bruce S
    |state=Massachusetts (MA)
    485 bytes (65 words) - 16:28, 16 March 2020
  • Facucho-Oliveira 2009 Stem Cell Rev Rep
    ...is hypothesized that reprogramming of somatic cells towards a pluripotent state, by somatic cell nuclear transfer (SCNT), transcription-induced pluripotenc
    2 KB (276 words) - 14:07, 19 December 2023
  • SUIT-001
    ...[[FNS]], [[Succinate pathway control state| S]] and [[SGp-pathway control state| SGp]] pathways) can be evaluated by using this SUIT protocol. SUIT-001 can :::+ Pathway control in ET state (N, NS, FNS, S and SGp pathways).
    5 KB (713 words) - 16:38, 5 March 2024
  • Silva 2019 ESCI2019
    ...he anaplerotic pathways [5]), etomoxir did not influence FAO in the OXPHOS state on Huh7 cells, while on mitochondria respiring on palmitoyl-CoA (40 µM) +
    5 KB (697 words) - 19:11, 10 January 2022
  • Dumollard 2007 Development
    ...ate impairs development, demonstrating the fundamental importance of redox state on early development.
    2 KB (298 words) - 07:09, 11 October 2023
  • Risiglione 2020 Int J Mol Sci
    ...try, we deeply investigated oxygen consumption related to each respiratory state in differentiated neuroblastoma cells exposed to the neurotoxin. Our result
    3 KB (367 words) - 17:36, 5 October 2023
  • Agil 2015 J Pineal Res
    ...001) and complex IV of electron transfer chain (''P'' < 0.05) and enhances state 3 respiration (''P'' < 0.001), respiratory control index (RCR) (''P'' < 0.0
    3 KB (337 words) - 08:04, 21 February 2020
  • Lemieux 2019a MiP2019
    ...ration (before the addition of ADP), OXPHOS capacity (in the ADP-activated state, coupled oxidative phosphorylation) and ET capacity (electron transfer capa
    6 KB (903 words) - 13:12, 26 September 2019
  • Collier S
    |state=Missouri (MO)
    261 bytes (33 words) - 09:34, 19 December 2014
  • Volt 2014 Abstract The 2014 Ageing Summit
    ...-related changes of the immune system involve a persistent proinflammatory state. This subclinical and chronic inflammation contributes further to enhance t
    2 KB (288 words) - 17:34, 7 November 2016
  • Ismaeel Ahmed
    |state=Kentucky (KY)
    278 bytes (36 words) - 13:38, 11 January 2023
  • US LA Baton Rouge Hand SC
    Louisiana State University |state=Louisiana (LA)
    1 KB (145 words) - 11:06, 21 July 2022
  • Spielmann 2022 Mamm Genome
    ...y through the electron transfer system (ETS) simultaneously with the redox state of ETS-reactive coenzyme Q (Q), or production of reactive oxygen species (R |topics=ADP, mt-Membrane potential, Redox state, Substrate, Q-junction effect
    4 KB (506 words) - 19:30, 5 March 2023
  • Tomar 2022 Biochim Biophys Acta Bioenerg
    ...OM mitochondria OxPhos efficiencies were higher than cortex mitochondria. State 3 respiration was low in heart mitochondria with succinate but increased si
    3 KB (386 words) - 11:58, 27 March 2023
  • Margulies SS
    |state=Pennsylvania (PA)
    266 bytes (31 words) - 09:17, 16 February 2018
  • Kozlov 2009 Biochim Biophys Acta
    ...or (AIF) to the nucleus, suggesting that the cells entered a pre-apoptotic state, but apoptosis was not executed. Monooxygenase activity of p450, representi
    2 KB (331 words) - 15:15, 20 March 2015
  • Garcia 2019 MiPschool Coimbra
    ...and 25°C. Surprisingly, no differences in coupled respiration and state 3/state 4 ratio were detected when substrates to the two main dehydrogenases in fli ...nects cytosolic processes with ETS, we can predict that the cellular redox state of the larvae is altered in the presence of AOX, affecting other metabolic
    4 KB (606 words) - 15:44, 26 June 2019
  • Aon 2010 Biochim Biophys Acta
    ...le keeping ROS overflow to a minimum by operating in an intermediate redox state. We show that at the extremes of reduction or oxidation of the redox couple
    2 KB (323 words) - 21:46, 24 September 2021
  • Droese 2009 Biochim Biophys Acta
    ...ffects of diazoxide reported in the literature. Depending on the metabolic state and the membrane potential of mitochondria, diazoxide-mediated inhibition o
    3 KB (376 words) - 16:49, 19 February 2018
  • Finck Brian N
    |state=Missouri (MO)
    267 bytes (36 words) - 09:16, 4 September 2023
  • Penjweini 2020 Redox Biol
    ...escence lifetime imaging (FLIM)-based measurement of nicotinamide coenzyme state. This offers a contemporaneous reading of metabolic activity through real-t
    2 KB (269 words) - 15:19, 5 November 2023
  • Ravasz 2024 Sci Rep
    |topics=mt-Membrane potential, Redox state
    2 KB (328 words) - 11:09, 27 January 2024
  • SUIT-038 O2 mt D091
    :::+ Pathway control in OXPHOS (N, NS, NSGp pathways) and in ET state (NSGp and SGp) can be observed. :::- LEAK state is not investigated.
    2 KB (332 words) - 11:21, 14 April 2023
  • Balmaceda 2024 Biochim Biophys Acta Mol Basis Dis
    ...ion rates, electron transfer system (ETS)-related coenzyme Q (mtCoQ) redox state and production of reactive oxygen species (ROS) in mouse brain and liver mi |topics=Redox state, Q-junction effect
    2 KB (345 words) - 09:44, 28 February 2024
  • Bernstein D
    |state=Connecticut (CT)
    296 bytes (34 words) - 14:03, 13 May 2019
  • Dufour S
    |state=Connecticut (CT)
    322 bytes (37 words) - 15:30, 21 August 2014
  • Laner 2015 Abstract MiPschool Greenville 2015
    ...ked substrates. Both protocols were designed to provide a common reference state of CI&II-linked ET capacity, in comparison to separate Complex I- and Compl ..., 5Comparative Exercise Physiol Lab, Center Veterinary Health Sc, Oklahoma State Univ, Stillwater, OK, US; 5-D Swarovski Research Lab, Dep Visceral Transpla
    5 KB (640 words) - 18:36, 10 January 2022
  • Blecha 2017 Free Radic Biol Med
    ...smal level remains unclear. As most somatic cells are in non-proliferative state, the features associated with the ETC in quiescence could account for some
    3 KB (402 words) - 12:26, 27 November 2017
  • Kingren Meagan
    |state=Arkansas (AR)
    300 bytes (35 words) - 12:24, 15 April 2024
  • Specht KS
    |state=Virginia (VA)
    274 bytes (36 words) - 18:02, 28 August 2018
  • DeBoer E
    |state=Pennsylvania (PA)
    286 bytes (34 words) - 11:15, 19 August 2019
  • US CO Fort Collins Hamilton K
    |institution=Colorado State University |state=Colorado (CO)
    676 bytes (89 words) - 19:05, 20 November 2018
  • SUIT-006 Q ce-pce D073
    ...b> consumption and the redox state of the Q-pool in S(Rot)-pathway control state in permeabilized cells- '''[[SUIT-006]]''' ...to be determined if used. Higher concentrations of Omy may inhibit the ET state.
    3 KB (443 words) - 14:38, 18 December 2023
  • SUIT-009 O2 ce-pce D016
    :::+ Cytochrome ''c'' test can be performed in the S-OXPHOS state.
    2 KB (312 words) - 00:09, 13 April 2021
  • Schappe T
    |state=Missouri (MO)
    318 bytes (40 words) - 09:47, 19 December 2014
  • Rich 1984 Biochim Biophys Acta
    ...med 'liquid state' and 'solid state' (Figs. 1A and B) [19,20]. In a liquid-state system, one or all components are freely diffusing and hence randomly arran ...exchange between free and bound forms of ubiquinone occurs. In such 'solid-state' reactions, reaction rate becomes limited by an internal rate constant of o
    12 KB (1,791 words) - 15:27, 16 July 2023
  • US MA Boston Kristal BS
    |state=Massachusetts (MA)
    614 bytes (76 words) - 09:38, 6 September 2021
  • Dutton 1989 Arch Biochem Biophys
    ...on formation. Superoxide dismutase, but not catalase, increased the steady-state level of reduced resorufin and considerably delayed its reoxidation. This i
    3 KB (422 words) - 21:45, 24 September 2021
  • Czerniczyniec 2015 J Bioenerg Biomembr
    ...t on respiratory chain. An increase of 2.2 fold in state 4 and 2.3 fold in state 3 in KCN-insensitive respiration was observed in striatal mitochondria from
    3 KB (338 words) - 12:00, 11 July 2017
  • Clanton 2013 Compr Physiol
    ...hways. Particular attention is paid to how O<sub>2</sub> affects the redox state of the cell, as well as the NO, H<sub>2</sub>S, and CO concentrations. We a
    2 KB (342 words) - 06:57, 28 June 2022
  • Sharpe 2021 Front Oncol
    ...can be toxic to cancer cells. Because weak magnetic fields influence spin state pairing in redox-active radical electron pairs, we hypothesize that they di
    2 KB (351 words) - 05:49, 6 February 2024
  • Chao 2019 Am J Physiol Cell Physiol
    ...phosphorylation. Coupled Complex-1 respiration decreased, while uncoupled State-4O, and complex-II increased significantly due to burn injury, particularly
    3 KB (356 words) - 11:41, 3 March 2020
  • Gruenig 2017 Toxicol In Vitro
    ...mulated state 2 complex II-linked respiration and both compounds inhibited state 3 respiration of complex IV. Mitochondrial uncoupling was confirmed for bot
    3 KB (332 words) - 11:25, 27 June 2019
  • Ostrovsky J
    |state=Pennsylvania (PA)
    337 bytes (38 words) - 09:31, 23 May 2017
  • Second
    ...value of the caesium frequency ∆''ν''<sub>Cs</sub>, the unperturbed ground-state hyperfine transition frequency of the caesium 133 atom, to be 9 192 631 770
    1,018 bytes (147 words) - 15:23, 3 April 2022
  • SUIT-003
    ...commended in the SUIT-003 have been designed to study the coupling control state of living cells. In order to study the [[LEAK respiration]], the phosphoryl
    6 KB (974 words) - 13:11, 17 November 2023
  • Votyakova Tatyana V
    |state=Pennsylvania (PA)
    502 bytes (61 words) - 17:58, 29 February 2020
  • Bouillaud 2013 Abstract MiP2013
    ...oncentration requires to be lower than 10 µM the establishment of a steady state for sulfide oxidation requires a continuous infusion of sulfide [4]. Becaus
    6 KB (870 words) - 11:04, 28 April 2017
  • Hu 2017 Proc Natl Acad Sci U S A
    ...'-tetramethyl-p-phenylenediamine (TMPD)+ascorbate. Interestingly, at basal state, cHet mice exhibited a higher H<sub>2</sub>O<sub>2</sub> level in the cytos
    3 KB (391 words) - 00:34, 1 March 2020
  • Hempenstall 2012 Mech Ageing Dev
    == Comment: Resting state == ...'starvation state' is strictly distinguished from metabolism in a 'resting state'. Mitochondria in the absence of added carbon-substrates are starved, gradu
    4 KB (512 words) - 10:30, 20 October 2017
  • Doerrier 2016 Abstract MitoFit Science Camp 2016
    ...l from the subsequent linear sequence of pathway control in the ET-pathway state (Figure 1). The [[SUIT_FNSGp(PGM)02 |SUIT RP2]] has a focus on OXPHOS capac
    3 KB (481 words) - 18:40, 10 January 2022
  • Palacka 2021 Int J Mol Sci
    ...onal uncoupler titration is necessary to reach the maximum O2 flow at this state.
    3 KB (457 words) - 22:56, 23 September 2023
  • Bugarski 2018 Am J Physiol Renal Physiol
    ...arkedly higher in S2 than in S1 but was insensitive to changes in RC redox state. Mitochondrial FP signal increased in response to palmitate but decreased i
    2 KB (363 words) - 10:18, 15 October 2023
  • Laner 2015 Abstract MiP2015
    ...ked substrates. Both protocols were designed to provide a common reference state of CI<small>&</small>II-linked ET capacity, in comparison to separate Compl ...Comparative Exercise Physiology Lab, Center Veterinary Health Sc, Oklahoma State Univ, Stillwater, OK, USA; 5-D Swarovski Research Lab, Dept Visceral Transp
    5 KB (671 words) - 18:35, 10 January 2022
  • Laner 2016 Abstract MitoFit Science Camp 2016
    ...ked substrates. Both protocols were designed to provide a common reference state of CI<small>&</small>II-linked ET-capacity, in comparison to separate Compl ...Comparative Exercise Physiology Lab, Center Veterinary Health Sc, Oklahoma State Univ, Stillwater, OK, USA; 5-D Swarovski Research Lab, Dept Visceral Transp
    5 KB (657 words) - 18:46, 10 January 2022
  • Krumschnabel 2014 Methods Enzymol
    ...mandatory for any fluorophore applied for probing mtMP, in any respiratory state, type of tissue and pathophysiological condition.
    5 KB (600 words) - 21:53, 23 April 2024
  • BR Campinas Carneiro EM
    |institution=State University of Campinas
    299 bytes (42 words) - 11:59, 4 July 2016
  • Toleikis 2005 Biosci Rep
    ...se of succinate oxidation compared to pyruvate+malate, (iv) the highest in State 4 with succinate as a substrate. Similar results were obtained with the iso
    2 KB (233 words) - 16:18, 13 November 2017
  • Funai Katsuhiko
    |state=Utah (UT)
    321 bytes (42 words) - 02:20, 1 March 2020
  • Houten 2016 Annu Rev Physiol
    ...atic and (cardio)muscular function. In this review, we present the current state of knowledge on the biochemistry and physiological functions of FAO and dis
    1 KB (212 words) - 07:17, 22 March 2023
  • Chabi 2019 MitoFit Preprint Arch EA
    ...'''3G:''' 10 mM glutamate as an additional NADH-linked substrate (N-OXPHOS state). '''4S:''' 10 mM succinate (NS-OXPHOS capacity). :'''5U:''' uncoupler titr
    8 KB (1,064 words) - 08:25, 8 January 2023
  • Godtliebsen 2023 Autophagy
    ...xpression of a pH-sensitive fluorescent mitochondrial reporter and applied state-of-the-art imaging techniques and image analysis. Our data showed a signifi
    3 KB (387 words) - 16:35, 11 July 2023
  • Chabi 2019 MiP2019
    ...rane. 3G: 10 mM glutamate as an additional NADH-linked substrate (N-OXPHOS state). 4S: 10 mM succinate (NS-OXPHOS capacity). 5U: uncoupler titrations to eva
    7 KB (971 words) - 12:55, 21 February 2023
  • Rosca MiP2010
    ...of [[CI substrate]]s (electron transport through CI/CIII/CIV) shows that [[State 3]] respiratory rates of cAMP (membrane permeable, dibutyryl cAMP)-incubate ...eshly-isolated cardiac IFM with 100 µm Sp-cAMP induces a 30% increase in [[State 3]] respiratory rates with CI substrates which was not changed by the uncou
    6 KB (831 words) - 09:56, 14 June 2023
  • Komlodi 2018 J Bioenerg Biomembr
    |additional=Succinate pathway control state, SUIT-009 AmR mt D021, Nigericin, BEC 2020.2, MitoFit 2021 Tissue normoxia,
    3 KB (439 words) - 04:34, 19 July 2022
  • Pallag 2022 Abstract Bioblast
    ...of oxygen consumption, membrane potential, NADH, and the ubiquinone redox state were correlated to ProDH activity and F<sub>1</sub>F<sub>O</sub>-ATPase dir
    4 KB (597 words) - 08:49, 28 July 2022
  • Liu 2009 J Biomed Sci
    ...ions where ROS are produced by mitochondria: oxidative glutamate toxicity, state IV respiration induced by oligomycin, and tumor necrosis factor-induced cel
    2 KB (260 words) - 23:33, 23 April 2023
  • US OK Stillwater Davis MS
    Oklahoma State University |state=Oklahoma (OK)
    1 KB (178 words) - 14:31, 13 July 2021
  • Baris 2015 Am J Physiol Regul Integr Comp Physiol
    ...eratures. Closer examination of the data also suggests that differences in State 3 respiration and Complex I activity between populations were greatest betw |keywords=Fundulus, State 3, Enzyme complexes, Mitochondria
    2 KB (340 words) - 16:52, 9 November 2017
  • SUIT-026 AmR mt D077
    ...dded to the chamber). The protocol is focused on [[LEAK respiration|LEAK]] state for the [[S-pathway]] to provide the conditions of high membrane potential ...the measurements the O<sub>2</sub> concentration will be changed and each state will be measure at an O<sub>2</sub> concentration >100 µM and <50 µM.
    4 KB (575 words) - 12:06, 31 August 2023
  • Basal respiration
    ...d at rest 12 to 14 hours after eating in a physically and mentally relaxed state at thermally neutral room temperature. Maintenance energy requirements incl |mitopedia concept=MiP concept, Respiratory state, Recommended
    7 KB (962 words) - 03:33, 18 December 2021
  • Abumrad Nada A
    |state=Missouri (MO)
    353 bytes (47 words) - 20:43, 7 March 2020
  • Chavanelle 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
    ...bility for this animal model to use palmitoylcarnitine or a very high LEAK state (or both!) #LEAK state was recorded
    1 KB (222 words) - 15:57, 7 November 2016
  • Kamath 2012 Abstract IOC72
    ...hondrial pathophysiology, maximal mitochondrial respiration in the coupled state is measured for quantitative determination of [[OXPHOS]]. In the current in
    4 KB (539 words) - 11:15, 8 June 2020
  • CA Guelph Ballantyne JS
    |state=Ontario (ON)
    393 bytes (57 words) - 10:13, 2 April 2019
  • Williams Ashley S
    |state=Tennessee (TN)
    393 bytes (44 words) - 10:44, 9 July 2020
  • US UT Salt Lake City Funai K
    |state=Utah (UT)
    316 bytes (43 words) - 11:07, 27 February 2024
  • Zeak Jennifer
    |state=Pennsylvania (PA)
    619 bytes (78 words) - 18:00, 29 February 2020
  • Steady state
    ...ntration (oxystat mode; Gnaiger et al 2000, Harrison et al 2015) or steady-state pH (pH-stat more), yielding an expanded flexibility in experimental design == Hyphenation: Steady state or steady-state? ==
    8 KB (1,115 words) - 03:00, 23 January 2023
  • Carneiro EM
    State University of Campinas
    379 bytes (50 words) - 13:09, 19 August 2014
  • Doeller 2005 Anal Biochem
    ...>S. Taken together, these findings suggest the existence of dynamic steady-state cellular H<sub>2</sub>S levels. The PHSS should facilitate the investigatio |topics=Redox state
    2 KB (350 words) - 11:59, 28 March 2018
  • Ballantyne JS
    |state=Ontario (ON)
    362 bytes (45 words) - 16:41, 12 February 2018
  • Warnau 2018 Proc Natl Acad Sci U S A
    ...membrane. Our simulations show that Q moves along the Q tunnel in a redox-state-dependent manner, with distinct binding sites formed by conserved residue c
    2 KB (325 words) - 19:40, 27 January 2024
  • Galli 2013 J Exp Biol
    ...act on subsequent ADP-stimulated O2 consumption (State III respiration) or State IV respiration. Results from this study demonstrate that turtle mitochondri
    3 KB (344 words) - 10:24, 9 November 2016
  • US IL Urbana Kwast K
    |state=Illinois (IL)
    375 bytes (54 words) - 09:13, 11 May 2018
  • Larsen 2009 Diabetologia
    ...ed with the other groups. In patients with type 2 diabetes, ADP-stimulated state 3 respiration per mg muscle with parallel electron input from complex I+II |topics=ADP, Redox state, Substrate
    3 KB (384 words) - 05:23, 8 February 2020
  • CA Hamilton Scott GR
    |state=Ontario (ON)
    407 bytes (61 words) - 17:07, 19 April 2023
  • Kakimoto 2021 Redox Biol
    ...e, showing it is independent of mitochondrial morphological changes. Redox state was altered by palmitate, as indicated by NAD(P)H quantification. Furthermo
    2 KB (301 words) - 10:21, 5 August 2021
  • Hickey 2009 Am J Physiol Cell Physiol
    ...sponses to increasing preloads. High-resolution respirometry showed higher state 3 (with excess ADP) respiration in SHR left ventricle fibers with complex I
    3 KB (397 words) - 10:43, 23 January 2019
  • Badger TM
    |state=Arkansas (AR)
    446 bytes (54 words) - 13:27, 16 March 2016
  • Stampley 2023 Physiol Rep
    ...-1</sup> ]) for all respiratory states (all p < 0.01), except for the LEAK state, after accounting for the mobilization of PBMCs. Future subtype-specific st
    2 KB (337 words) - 15:40, 20 June 2023
  • Robb 2018 J Biol Chem
    ...ction by RET is highly responsive to small changes in Δp and the CoQ redox state, indicating that complex I RET represents a major mode of mitochondrial red
    3 KB (479 words) - 12:16, 22 March 2023
  • Noncoupled respiration
    ...ical) [[uncoupled respiration]], to give a label to an effort to reach the state of maximum uncoupler-activated respiration without inhibiting respiration. ...is due to the increase of mt-membrane potential in the LEAK versus OXPHOS state, causing a corresponding increase of the proton leak driven by the higher p
    12 KB (1,557 words) - 20:27, 19 March 2022
  • Kunst 2023 Biomedicines
    ...oxygen species (ROS) and (ii) define the transition from a balanced REDOX state to oxidative stress. Further, we (iii) describe the role of ROS in regulati
    2 KB (291 words) - 23:31, 18 December 2023
  • Simon M
    |state=Pennsylvania (PA)
    401 bytes (48 words) - 16:46, 18 August 2014
  • Hollis 2003 Biochim Biophys Acta
    ...concentrations ([O(2)]), endogenous nitric oxide (NO) modulates the redox state of the mitochondrial electron transport chain (ETC), and whether such an ac |topics=Cyt c, Flux control, Inhibitor, Oxygen kinetics, Redox state
    2 KB (314 words) - 14:45, 1 December 2015
  • Hancock S
    |state=Pennsylvania (PA)
    348 bytes (40 words) - 17:51, 12 February 2018
  • Aon 2015 J Gen Physiol
    ...g minimal levels of H<sub>2</sub>O<sub>2</sub> emission, especially during state 3 respiration, when the energetic output is maximal. This suggests that the
    3 KB (418 words) - 15:28, 7 November 2016
  • Cytochrome c control efficiency
    ...is the [[reference state]] with stimulated flux; CHNO is the [[background state]] with CHNO substrates, upon which c is added: :::: It is important '''not''' to add cytochrome ''c'' in a [[LEAK state]]: There is always an unexplained activation of respiration, unrelated to t
    11 KB (1,496 words) - 11:35, 21 January 2022
  • Bouillaud 2012 Abstract Bioblast
    ...onent to sulfide oxidation probably because of the change in its reduction state.
    6 KB (835 words) - 10:26, 9 November 2016
  • Abella Gioscia Pilar
    |state=
    409 bytes (49 words) - 12:24, 29 June 2023
  • Selivanov 2012 PLoS Comput Biol
    |topics=mt-Membrane potential, Redox state, Substrate
    3 KB (350 words) - 18:00, 29 February 2020
  • Van Hoose P
    |state=Kentucky (KY)
    385 bytes (48 words) - 17:13, 13 February 2018
  • Byro Melissa
    |state=Pennsylvania (PA)
    389 bytes (45 words) - 14:05, 13 May 2019
  • SUIT-001 O2 pfi D002
    :::+ Pathway control in ET state (N, NS, FNS, S and SGp pathways). :::+ Oct is added in ET state to avoid uncoupler effect with fatty acids.
    3 KB (427 words) - 18:32, 5 March 2024
  • Holloway 2018 Cell Rep
    ...the fraction of electron leak to H<sub>2</sub>O<sub>2</sub>, or the redox state of the muscle. These data establish that a reduction in mitochondrial ADP s
    2 KB (301 words) - 13:29, 7 March 2020
  • Gnaiger 2018 MiPschool Tromso A2
    ...ent is constant along the diffusion path (in a homogenous medium at steady state; Fick's law of diffusion). Therefore, the concentration gradient of a conti ...h ''RT'' [J·mol<sup>-1</sup>]. The diffusion pressure difference at steady-state is the product of a concentration (activity; [x·m<sup>-3</sup>] or [mol·m
    8 KB (1,154 words) - 14:59, 13 February 2020
  • Sure Venkata
    |state=Louisiana (LA)
    448 bytes (52 words) - 15:57, 27 June 2023
  • Ea T
    |state=Pennsylvania (PA)
    408 bytes (47 words) - 11:09, 14 February 2018
  • MacDonald 2018 IOC130
    ...bient H<sub>2</sub>O<sub>2</sub> concentration, mitochondrial bioenergetic state and activity of the scavenging enzyme systems. Indeed, manipulation of mito
    3 KB (419 words) - 14:04, 23 May 2018
  • Petrenko 2010 Cryobiology
    ...ter DNP wash-out during WR, an improvement in the mitochondrial functional state (higher respiratory control indices and ATP levels, and a decrease in V(4) ...upling, Mitochondrial respiration, Bile formation, Pro-oxidant/antioxidant state
    2 KB (293 words) - 12:13, 8 November 2016
  • Fahimi 2022 Trends in Chemistry
    ...suggest that mitochondria are 10oC hotter than their surroundings. Steady-state theoretical estimates place this difference at a maximum of 10-5 oC. This m
    1 KB (213 words) - 22:34, 8 November 2023
  • Shankar K
    |state=Arkansas (AR)
    452 bytes (53 words) - 09:50, 20 February 2023
  • Jayakumari 2020 J Diabetes
    ...bolism and regulation. Decreased glutamate but unchanged pyruvate-mediated state 3 respiration were also observed in diabetic subjects.
    3 KB (381 words) - 16:54, 1 July 2020
  • Giulivi 2008 Biochem J
    ...ondria. Addition of tartronic acid resulted in 92 % and 90 % inhibition of State 3 oxygen uptake respectively. This result indicated that exogenously added
    4 KB (555 words) - 18:53, 15 March 2021
  • Borsheim Elisabet
    |state=Arkansas (AR)
    519 bytes (63 words) - 09:53, 15 February 2021
  • Hayward 2018 Thesis
    ...ring hibernation (in torpor or interbout euthermia; IBE). Anoxia decreased state 3 respiration in all groups, but mitochondria isolated from torpid squirrel
    2 KB (242 words) - 16:13, 4 February 2019
  • Gnaiger 2008 POS
    ...t time to evaluate the stability of respiratory activity in each metabolic state and to permit complex titration regimes in living cells or in permeabilized ...ncoupled flux (capacity of the Electron transfer-pathway, [[ET-capacity]]; state ''E'') is reached at 5.5 μM FCCP. The ''L/E'' ratio is 0.10. Respiration i
    5 KB (638 words) - 00:30, 5 March 2022
  • US VA Richmond Virginia Commonwealth Univ
    |state=Virginia (VA)
    521 bytes (75 words) - 08:37, 4 July 2018
  • Zoppi C
    State University of Campinas
    411 bytes (51 words) - 18:24, 12 February 2018
  • US UT Salt Lake City Richardson RS
    |state=Utah (UT)
    392 bytes (53 words) - 16:32, 3 November 2022
  • Gutierrez 2020 Sci Signal
    ...calnexin stimulated the ATPase activity of SERCA by maintaining its redox state. This function enabled calnexin to control how much ER Ca<sup>2+</sup> was
    2 KB (287 words) - 18:41, 7 July 2020
  • Cordero-Reyes 2014 J Mol Cell Cardiol
    ...ochondria had greater respiratory control ratios and lower ADP-independent state 4 rates than NFLV mitochondria for GM, PM and PC substrates demonstrating t ...ase-polymerized chain reaction, state 3 respiration to the uncoupled rate, state 4 respiration to uncoupled rate, subsarcolemmal mitochondria, succinate
    4 KB (532 words) - 17:25, 9 November 2017
  • Wade MR
    |state=Indiana (IN)
    446 bytes (53 words) - 11:09, 14 February 2018
  • US MO St Louis Finck BN
    |state=Missouri (MO)
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  • Kassahun 2018 DNA Repair (Amst)
    ...opy number, reduced mitochondrial membrane potential, and increased steady-state levels of reactive oxygen species. Consistently, ''nth-1'' mutants express
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  • Caito 2015 Antioxid Redox Signal
    |topics=Calcium, Redox state
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  • Othonicar 2023 MiPschool Obergurgl
    ...chnology, School of Agricultural and Veterinary Sciences, UNESP- São Paulo State University, Jaboticabal, SP, Brazil
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  • Fiorini 2016 Comp Biochem Physiol B Biochem Mol Biol
    ...rella V (2016) Lipid unsaturation ''per se'' does not explain the physical state of mitochondrial membranes in ''Mytilus galloprovincialis''. Comp Biochem P ...hondria could produce an environment which somehow approaches the physical state of mammalian mitochondrial membranes. Thus, as an adaptive strategy, the in
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  • Pallag 2022 MitoFit Proline
    ...easuring oxygen consumption, membrane potential, NADH and ubiquinone redox state using the NextGen-O2k (Oroboros Instruments) and correlated to ProDH activi
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  • SUIT-026 AmR mt D064
    ...dded to the chamber). The protocol is focused on [[LEAK respiration|LEAK]] state for the [[S-pathway]] to provide the conditions of high membrane potential ...an Event&Mark for the uncoupler titration (4U) after ADP (3D) to obtain ET-state.
    4 KB (609 words) - 00:00, 13 April 2021
  • Fisher-Wellman 2012 Trends Endocrinol Metab
    |topics=Redox state
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  • Protti 2006 Crit Care
    ...systemic inflammatory response. The regulated induction of a hypometabolic state resembling hibernation may protect the cells from dying once energy failure
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  • US PA Philadelphia Margulies S
    |state=Pennsylvania (PA)
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  • Carriere 2019 Academic Press
    ...bution, and turnover as well as their impact on the overall cellular redox state are determinant for the cellular processes underlying adipose tissues metab
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  • Boushel 2012 Am J Physiol Regul Integr Comp Physiol
    ...Indo (15%) compared to CON. The results indicate that indomethacin reduces State 3 mitochondrial respiration primarily at Complex I of the respiratory chain
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  • Yamauchi 2022 Sci Rep
    |topics=ADP, Redox state, Substrate
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  • Gutman 1972 FEBS Lett
    ...an interact, in a spill-over mechanism, with other pools. The final steady state reduction of each pool, determined by the influx and efflux of electrons, w
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  • Griguer CE
    |state=Alabama (AL)
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  • Towheed Atif
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  • Ortiz-Gonzales X
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  • Montaigne 2010 Toxicol Appl Pharmacol
    ...ely prevented mitochondrial membrane potential dissipation, cardiac energy state and dysfunction. These results suggest that in intact hearts an impairment
    3 KB (339 words) - 11:49, 22 December 2020
  • Benard 2011 Springer
    ...s of regulation of mitochondrial fusion and fission by the cellular energy state. Hence, in complement to pioneering concepts of metabolic control which onl
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  • Flux analysis - DatLab
    == Step analysis and state analysis == ...threshold level, below which such data sets would be excluded from steady-state analysis.
    4 KB (640 words) - 11:46, 25 March 2022
  • Matallo MiP2010
    ...stically significantly higher concentration when compared to the uncoupled state (P<0.05), in cells at routine respiration. In contrast, at 25 °C the Na2S
    7 KB (955 words) - 15:31, 24 January 2018
  • Davis Michael S
    Oklahoma State University, US |state=Oklahoma (OK)
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  • Angelin Alessia
    |state=Pennsylvania (PA)
    494 bytes (57 words) - 17:51, 12 February 2018
  • Sumbalova 2016a Abstract MitoFit Science Camp 2016
    ...10 mM succinate + 0.5 µM rotenone (CII protocol) in OXPHOS and ET-pathway state in rat brain mitochondria. ...balova Figure2.jpg|left|600px]] ''Figure 2. A:'' The respiration in OXPHOS state determined in rat brain mitochondria with CI-linked substrates, CI&II-linke
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  • Torres 2018 Cell Metab
    ...eas E2 therapy restored-mitochondrial respiratory function, cellular redox state (GSH/GSSG), and insulin sensitivity in skeletal muscle. E2 was detected by
    2 KB (335 words) - 10:01, 26 April 2023
  • Hals 2015 PLoS One
    ...pling, comprising about 50% of oxygen consumption in the basal respiratory state. Hypoxia followed by re-oxygenation increased maximal overall respiration.
    3 KB (396 words) - 14:30, 13 November 2017
  • Doerrier 2018 MiP2018a
    ...or NADH&Succinate pathway in OXPHOS state; 5U, uncoupler, for obtaining ET-state with NADH&Succinate linked-substrates; 6Rot, rotenone for inhibiting Comple
    5 KB (679 words) - 19:07, 10 January 2022
  • Anderson EJ
    |state=Iowa (IA)
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  • Tarpey 2019 J Biol Chem
    ...membrane potential, but no changes in the NAD(P)H/NAD(P)<sup>+</sup> redox state. Protein content and dehydrogenase activity results corroborated these find
    3 KB (393 words) - 11:24, 3 March 2020
  • Kamunde 2018 Free Radic Biol Med
    ...bient H<sub>2</sub>O<sub>2</sub> concentration, mitochondrial bioenergetic state and activity of the scavenging enzyme systems. Indeed, manipulation of mito
    3 KB (465 words) - 13:30, 7 March 2020
  • Doerrier 2018 MiP2018c
    ...ned NS-OXPHOS capacity was evaluated after adding 10 mM succinate (4S). ET-state was assessed after uncoupler titrations for NS-ET (5U) and S-ET capacity af
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  • Trumbeckaite 2001 Eur J Biochem
    significant decrease of state 3-respiration for the substrates decreased temporal stability of the rate of state
    3 KB (366 words) - 10:54, 23 January 2019
  • Du 2016 J Exp Biol
    ...ension at which hypoxia inhibits respiration by 50%) was lower in the LEAK state than during maximal respiration, and killifish mitochondria endured anoxia-
    2 KB (331 words) - 13:41, 7 March 2020
  • SUIT-001 O2 mt D001
    :::+ Pathway control in ET state (N, NS, FNS, S and SGp pathways). :::+ Oct is added in ET state to avoid uncoupler effect with fatty acids.
    4 KB (507 words) - 18:31, 5 March 2024
  • Pacheco 2008 Master Thesis
    ...ondrial respiration comparable to fresh muscle. However, the magnitudes of state 3 (ADP-driven) respiration rates for complex I substrates with malate and g ...e were lower than that of fresh muscle tissue. The significant increase in state 3 respiration upon addition of cytochrome c indicates that cryopreservation
    2 KB (285 words) - 09:40, 8 November 2016
  • Crandall A
    |state=Utah (UT)
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  • Oliva 2011 PloS One
    ...sistant cells and xenolines, and basal respiration (state 2), proton leak (state 4), and mitochondrial ROS production were significantly lower in TMZ-resist
    3 KB (399 words) - 15:59, 17 February 2015
  • Irving 2022 Abstract Bioblast
    ...ure respiration rates in duplicate during LEAK (State 4), OXPHOS capacity (State 3), and electron transfer capacity (ET) states in permeabilized hypothalami ::::# Louisiana State University
    6 KB (904 words) - 08:41, 28 July 2022
  • Bai 2016 PLOS ONE
    ...ia is generally measured during state 4 respiration (no ATP production) or state 3 (maximal ATP production at high ADP availability). However, mitochondria
    2 KB (299 words) - 16:52, 9 November 2017
  • Uecal 2016 J Neurotrauma
    ...of NO in the contralateral cortex. NO-mediated impairment of mitochondrial state 3 respiration dependent on complex I substrates was transient and confined
    2 KB (335 words) - 13:13, 10 January 2017
  • Bustamante 2008 Neurochem Res
    ...months rats as compared with 1-month-old rats. No changes were observed in state 4 respiration rates. These results could indicate 1 that nNOS and eNOS mRNA
    3 KB (427 words) - 14:40, 20 March 2015
  • De Villiers 2018 Adv Exp Med Biol
    ...processes. Despite many studies in this field, it is still not possible to state with certainty whether ROS measured during adipocyte differentiation are a
    2 KB (316 words) - 04:36, 10 November 2023
  • Seminotti Bianca
    |state=Pennsylvania (PA)
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  • Schaefer 2017 Neurophotonics
    ...aled mitochondrial matrix pH as a decisive factor in imaging NAD(P)H redox state. By combining both parameters, we illustrate a quantitative, high-resolutio |keywords=NAD(P)H-FLIM, Energy metabolism, Matrix pH, Mitochondria, Redox state, Respirometry
    2 KB (264 words) - 10:43, 30 January 2018
  • Falk Marni J
    |state=Pennsylvania (PA)
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  • Makrecka-Kuka 2017 MiP2017
    ...ghtly impaired mitochondrial functionality (significant decrease in OXPHOS state respiration by 10%) just 24h after induction of endotoxemia.
    3 KB (453 words) - 12:17, 3 October 2017
  • Laner 2016 Abstract Mito Xmas Meeting Innsbruck
    ...ked substrates. Both protocols were designed to provide a common reference state of NS-linked ET capacity, in comparison to separate N- and S-linked pathway ::::# Dept Health Exercise Sc, Colorado State Univ, Fort Collins, CO, USA
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  • US TX San Antonio Musi N
    |state=Texas (TX)
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  • Iyer 2022 Abstract Bioblast
    ...ygen consumption ''Rox'' after inhibition by rotenone and antimycin A (ROX state), and LEAK respiration ''L''. The glycoBHI was based on four key aspects of
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  • O2k-Publications: Topics
    | style="text-align:left"|[[O2k-Publications: Redox state |Redox state]] ...egory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::Redox state]] |format=count}}
    62 KB (7,038 words) - 14:31, 22 August 2023
  • SUIT-001 O2 ce-pce D003
    :::+ Pathway control in ET state (N, NS, FNS, S and SGp pathways). :::+ Oct is added in ET state to avoid uncoupler effect with fatty acids.
    4 KB (557 words) - 09:53, 7 July 2022
  • US IN Indianapolis Brozinick JT
    |state=Indiana (IN)
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  • Picard Martin
    |state=Pennsylvania (PA)
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  • Han 2017 MiP2017
    ...), the succinate-pathway and the Complex IV single step. In addition, LEAK state was measured in the absence of ADP and the integrity of the outer mitochond
    4 KB (512 words) - 23:55, 17 March 2019
  • Jaramillo-Jimenez 2023 Mitochondrion
    ...nitive performance was measured annually over 5-years with the Mini-mental State Examination. Longitudinal mixed-effects Tobit models evaluated each baselin
    2 KB (334 words) - 16:40, 13 October 2023
  • Courtes 2020 Brain Res Bull
    ...atment also increased respiratory control ratio (RCR), an indicator of the state of mitochondrial coupling, which is related to the mitochondrial functional
    3 KB (442 words) - 18:21, 6 November 2020
  • US PA Philadelphia Ganetzky R
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    |state=Pennsylvania (PA)
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  • Doerrier 2019 MitoFit Preprint Arch EA
    ...''<sub>O2,PM</sub>)/''I''<sub>O2,''c''PM</sub>, exceeded 0.1 in the OXPHOS-state (Fig. 1; steps 2D and 2c). For abbreviations see Figure 1 and Gnaiger et al ...'''3G''': 10 mM glutamate as an additional NADH-linked substrate (N-OXPHOS state). '''4S''': 10 mM succinate (NS-OXPHOS capacity). '''5U''': uncoupler titra
    9 KB (1,242 words) - 08:27, 8 January 2023
  • Jezek 2020 Antioxid Redox Signal
    |abstract=Significance: Cancer cells are stabilized in an undifferentiated state similar to stem cells. This leads to profound modifications of their metabo
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  • Tunholi 2016 J Invertebr Pathol
    ...comparison with the respective control group (5.14±0.25). In the uncoupled state, the infected snails consumed about 62% less oxygen than the infected snail
    2 KB (322 words) - 16:19, 13 November 2017
  • Wen 2020 Biomedicines
    ...ardiac mitochondrial dysfunction was supported by the finding of decreased state 3 respiration, decreased mitochondrial electron transport chain activity in
    2 KB (315 words) - 18:23, 9 December 2020
  • Rai 2022 G3 (Bethesda)
    ...mics analysis reveals that a Gpdh1 mutant stock maintained in a homozygous state exhibits larval metabolic defects that significantly differ from those obse
    3 KB (446 words) - 18:01, 3 September 2023
  • Kasparova 2006 Neurochem Int
    antioxidants CoQ(10)+vitamin E. We used dynamic and steady-state methods of ''in vivo'' phosphorus magnetic resonance spectroscopy ((31)P MR
    3 KB (424 words) - 15:42, 27 March 2018
  • Liang 2021 Biomed Pharmacother
    ...ompromised following CA and I/R injury, and the major affected respiratory state is complex I-linked respiration. Furthermore, the heart and the brain respo
    3 KB (410 words) - 13:26, 10 November 2021
  • Sobotka 2015 Physiol Res
    ...te respiration in an uncoupled state was less pronounced than in a coupled state in all the experimental models tested. When the concentration dependence of
    2 KB (208 words) - 16:09, 13 November 2017
  • Chicco 2016c Abstract MitoFit Science Camp 2016
    1-Depts. Biomedical Sci, 2-Cell Mol Biol, 3-Biochem Mol Biol, Colorado State Univ, Fort Collins, USA, CO. - [email protected]
    4 KB (606 words) - 15:34, 20 October 2017
  • SUIT-014 O2 pfi D042
    ...b>''P''</sub>. SUIT-004 should be chosen for the additive effect in the ET-state.
    3 KB (487 words) - 11:39, 29 February 2024
  • Chicco 2013 Abstract MiP2013
    ...Physiology Laboratory, Department of Health and Exercise Science, Colorado State University, Fort Collins, CO, USA; 2 - Cell and Molecular Biology Program, Colorado State University, Fort Collins, CO, USA;
    5 KB (691 words) - 11:16, 8 June 2020
  • Oroboros Ecosystem Agenda 2024 Archive
    ...ects on oxidative phosphorylation, mitochondrial membrane potential, redox state of coenzyme Q, and calcium uptake]]'' |''' New year, new state? What is REN state? '''<br>
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  • Guadalupe-Grau 2014 J Sports Sci
    ...hropoietin treatment increased mitochondrial O2 flux during ADP stimulated state 3 respiration in the presence of complex I and II substrates (malate, gluta
    3 KB (347 words) - 15:45, 5 March 2019
  • Pesta 2010 MiP Abstract
    ...rylation system]] (stimulation by FCCP titration to induce the non-coupled state of [[electron transport system]] (ET-pathway) capacity. [[Residual oxygen c
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  • Guadalupe-Grau 2015 J Sports Sci
    ...treatment increased mitochondrial O<sub>2</sub> flux during ADP stimulated state 3 respiration in the presence of complex I and II substrates (malate, gluta
    3 KB (344 words) - 15:46, 5 March 2019
  • US TN Nashville Wasserman DH
    |state=Tennessee (TN)
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  • Lim 2010 Proteomics
    |topics=Redox state
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  • Archer 1993 Circ Res
    ...S) by the ETC. We hypothesized that this shift toward a more reduced redox state elicits vasoconstriction by inhibition of K<sup>+</sup> channels. Pulmonary
    2 KB (362 words) - 13:46, 25 April 2022
  • Bettinazzi 2019 Cryobiology
    ...red to fresh tissues, independently of substrates combination, respiratory state and normalizing factor. However, the negative impact is not reflected at th
    2 KB (252 words) - 12:17, 9 July 2019
  • Ling 2019 Am J Clin Nutr
    |abstract=Constitutional thinness (CT) is a state of low but stable body weight (BMI ≤18 kg/m<sup>2</sup>). CT subjects hav
    4 KB (535 words) - 15:32, 15 October 2019
  • Kahraman 2007 Neurochem Res
    ...man S, Fiskum G (2007) Anoxia-induced changes in pyridine nucleotide redox state in cortical neurons and astrocytes. Neurochem Res 32:799-806. ...argon (2) Exogenous glucose is necessary to maintain NAD(P)H in a reduced state during metabolic anoxia in neurons but not astrocytes (3) Neurons undergo a
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  • Groeger 2010 Crit Care
    ...ion (1 to 2 Mio cells/ml respiration medium) was achieved in the uncoupled state by adding pyruvate, malate, glutamate and succinate as respiratory substrat
    3 KB (463 words) - 14:26, 13 November 2017
  • Porter Craig
    |state=Arkansas (AR)
    575 bytes (71 words) - 11:02, 21 July 2022
  • Hickey 2014 Abstract MiP2014
    ...also produced more net ROS, relative to oxygen flux (ROS/O) in the OXPHOS state. While Δ''Ψ'' did not differ between groups, the time to develop Δ''Ψ'' ...-1</sup>∙mg<sup>-1</sup>) in normoxia and anoxia. (c) The active or steady-state ~P/O ratio was then determined from the rate of ATP synthesised relative to
    4 KB (547 words) - 17:26, 7 November 2016
  • Vuda 2012 Innate Immun
    ...4 respiration were measured for respiratory chain complexes I and II, and state 3 for complex IV using high-resolution respirometry, and respiratory contro
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  • Aparicio-Trejo 2018 Free Radic Biol Med
    ...C preadministration was able to prevent mitochondrial bioenergetics, redox state and dynamics alterations as well as renal damage. The protective effects of
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  • Boushel 2007 Diabetologia
    .../sub> flux expressed per mg of muscle (fresh weight) during ADP-stimulated state 3 respiration was lower ( ''p''<0.05) in patients with type 2 diabetes in t
    5 KB (652 words) - 13:56, 27 December 2021
  • Calzia 2015 Abstract MiP2015
    ...uncoupler FCCP in order to achive the maximum respiration in the uncoupled state and the coupling (LEAK/ET-pathway)-ratio. After blocking mitochondrial resp
    3 KB (436 words) - 14:52, 23 January 2019
  • Pirkmajer 2019 MiP2019
    ::::#National Research Tomsk State Univ, Tomsk, Russia: - [email protected]
    1 KB (198 words) - 12:23, 18 September 2019
  • Garlid AO 2012 Abstract Bioblast
    Department of Biology, Portland State University, Portland, Oregon, USA; Email: [email protected]
    4 KB (617 words) - 20:10, 4 January 2018
  • Vorotnikov 2022 Biomedicines
    ...should be available to cultured endothelial cells to adjust the metabolic state and withstand the immediate apoptosis. We discuss the role of carnitine, cr
    2 KB (275 words) - 19:02, 17 September 2023
  • Mallick 2015 Cell Calcium
    ...r VK, Dash D (2015) Prion protein fragment (106-126) induces prothrombotic state by raising platelet intracellular calcium and microparticle release. Cell C ...ence are pro-coagulant in nature, exposure to prion favored a thrombogenic state in the organism.
    2 KB (275 words) - 16:19, 9 November 2016
  • Bryant 2018 Thesis
    ...ase liver mitochondrial capacity and coupling as indicated by increases in state III, respiratory control and ADP/O ratios (Chapter 3). Interestingly, I als
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  • Gellerich 2008 J Biol Chem
    ...rial Ca<sup>2+</sup>. In contrast, htt51Q mitochondria showed a deficient state 3 respiration, a lower sensitivity to Ca<sup>2+</sup> activation, and a hig
    3 KB (427 words) - 14:58, 8 June 2015
  • Karadayian 2015 Neuroscience
    ...nd treated mice. The present work demonstrates that the physiopathological state of AH involves mitochondrial dysfunction in mouse cerebellum showing the lo
    2 KB (345 words) - 12:00, 11 July 2017
  • Lamberti 2011 Plant Signal Behav
    |title=Lamberti G, Drurey C, Soll J, Schwenkert S (2011) The phosphorylation state of chloroplast transit peptides regulates preprotein import. Plant Signal B
    1 KB (145 words) - 10:15, 9 November 2016
  • Aye 2022 Am J Obstet Gynecol
    ...that placental metabolic reprogramming reflects the dynamic physiological state allowing the tissue to adapt to developmental changes and respond to preecl
    2 KB (278 words) - 22:57, 8 November 2023
  • SUIT-026 O2 mt D063
    ...an Event&Mark for the uncoupler titration (4U) after ADP (3D) to obtain ET-state.
    2 KB (254 words) - 00:01, 13 April 2021
  • Christiansen 2015 Am J Physiol Heart Circ Physiol
    ...physiology of HCM and support the hypothesis that restoration of the redox-state in the mitochondria is beneficial in the treatment of HCM.
    3 KB (373 words) - 17:34, 25 February 2020
  • Simonin 2012 Biochem J
    ...SNAP or DETA-NONOate caused a 70 % reduction in oxygen consumption rate in state 3 (stimulated with 1 mM of ADP). This inhibition was followed by a signific
    2 KB (337 words) - 10:17, 9 November 2016
  • Kuboyama 1962 Biochem Biophys Res Commun-X
    ...ibed. The variation in composition is apparently due to the polymerization state of the cytochrome oxidase employed in the reaction mixture. Among these for
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  • Wallace DC
    |state=Pennsylvania (PA)
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  • IOC recommended reading
    ::::» Steady-state injection respirometry
    12 KB (1,521 words) - 14:23, 15 May 2023
  • Egan 2023 Physiol Rev
    ...adation. A critical appraisal of methodological approaches and the current state of knowledge informs a series of recommendations offered as future directio
    2 KB (283 words) - 15:19, 5 October 2023
  • Shu 2023 Front Immunol
    ...ctions when the ROS concentration is too high to reach an oxidative stress state. We also summarize the main features and energy metabolism of CD4+ T-cell a
    2 KB (259 words) - 14:08, 4 August 2023
  • Hong 2022 Cell Stem Cell
    ...ion (OXPHOS) metabolism and mitophagy and increased oxidative stress. This state results in muscle regenerative failure, which is caused by the reduced prol
    2 KB (331 words) - 18:26, 7 September 2022
  • Schwartz 2022 JACC Basic Transl Sci
    ...in poorly understood. Many studies have described HF as an energy-deprived state characterized by a decline in adenosine triphosphate production, largely dr
    2 KB (287 words) - 17:13, 22 October 2023
  • Chance 1962 J Biol Chem
    ...nts of adenosine diphosphatc will lead to reestablishment of the inhibited state of succinate oxidation after a short burst of respiration. 2. The inhibited state is not relieved by either phosphate or phosphate acceptors.
    2 KB (260 words) - 17:18, 9 November 2017
  • Severin 2013 Abstract MiP2013
    1 - Faculty of Bioengineering and Bioinformatics, Moscow State University, Russia; 2 - Belozersky Institute of Physico-Chemical Biology, Moscow State University, Russia;
    3 KB (365 words) - 11:23, 28 April 2017
  • Sobotka 2017 Abstract MITOEAGLE Barcelona
    ...rol factor for octanoyl-carnitin in electron transport system (ET-pathway) state was significantly increased from 1- to 6-week periods. Maximal OXPHOS and E
    3 KB (469 words) - 11:03, 18 March 2020
  • Gizatullina 2011 Mitochondrion
    ...erload induced by addition of 20μM Ca(2+) caused a significant decrease of state 3(glu/mal) (-45 to -55%) which was almost completely prevented in the prese
    3 KB (348 words) - 17:05, 7 November 2016
  • SUIT-001 O2 ce-pce D004
    :::+ Pathway control in ET state (N, NS, FNS, S and SGp pathways). :::- Oct is not added in ET state.
    4 KB (541 words) - 10:02, 22 January 2024
  • CH Bern Djafarzadeh S
    ...pmol/s/mg, p=0.043, Wilcoxon Test]. The respiratory control ratio (state 3/state 4) remained unchanged [baseline: 9.7 (8.4-12.6); end: 9.3 (7.8-18.3)].
    3 KB (404 words) - 10:00, 20 February 2020
  • US AR Little Rock Borsheim E
    |state=Arkansas (AR)
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  • Som 2023 Am J Physiol Cell Physiol
    |topics=mt-Membrane potential, Redox state
    3 KB (409 words) - 22:25, 28 October 2023
  • Skemiene 2015 FEBS J
    ...ly in the absence of CoQ<sup>1</sup>. Dp3G and Cy3G but not Pg3G increased state 3 respiration and ATP synthesis with NADH-dependent substrates in mitochond
    2 KB (279 words) - 04:47, 12 February 2020
  • Tripodi 2018 Biochim Biophys Acta Mol Cell Res
    ...n the form of ATP, they are also involved in maintenance of cellular redox state, conversion and biosynthesis of metabolites and signal transduction. Most m
    3 KB (334 words) - 16:43, 3 May 2024
  • Ravasz 2019 Abstract IOC141
    ...neously oxygen partial pressure and NADH autofluorescence or quinone redox state we show that in isolated mitochondria Complex I utilizes endogenous quinone
    3 KB (450 words) - 12:45, 3 April 2021
  • Bioblast quiz
    ...K respiration is crucial for understanding the non-phosphorylating resting state where energy is used to counteract proton leaks, preserving ionic gradients ...mitochondrial membrane potential, providing insights into the bioenergetic state of the mitochondria.
    36 KB (5,157 words) - 12:10, 12 April 2024
  • Luther 2023 Am J Physiol Renal Physiol
    ...on comprised of a reduction of the RCR and an increased CII/CI-relation in State 3 was demonstrated in an ovine model of SA-AKI. However, the disturbed rela
    3 KB (383 words) - 16:36, 2 May 2023
  • Brozinick Joseph T
    |state=Indiana (IN)
    570 bytes (75 words) - 12:51, 16 March 2020
  • Naimi 2011 Clin Physiol Funct Imaging
    ...y were that (i) routine [[State 2]] respiration was higher in COPD; (ii) [[State 3]] respiration in the presence of ADP was similar in both groups with subs
    2 KB (300 words) - 05:23, 8 February 2020
  • Hauptmann 2009 Neurobiol Aging
    ...tio and reduction of COX IV activity. We observed significant decreases in state 3 respiration and FCCP-uncoupled respiration in non-tg mice after treatment
    2 KB (308 words) - 17:04, 19 February 2018
  • Hirzel 2013 J Recept Signal Transduct Res
    ...curcumin oxidizing radicals only. All three substances slightly decreased state III respiration immediately after addition. After 24 h of treatment, Mito
    2 KB (267 words) - 04:31, 12 February 2020
  • Sumbalova 2015 Abstract MiP2015
    ...cence may comprise a mixture of signals from a fluorescent dye in its free state and bound to membranes or proteins, and corrections may be difficult for ob ...IIP state when the mt-membrane potential is low already in the uninhibited state. The increase of TPP<sup>+</sup> concentration from 1.5 to 3 µM did not ch
    6 KB (883 words) - 18:36, 10 January 2022
  • US IA Iowa City Anderson EJ
    |state=Iowa (IA)
    1 KB (236 words) - 16:21, 3 November 2022
  • Complex II ambiguities
    ...Ranji M, Eells JT (2020) Photobiomodulation preserves mitochondrial redox state and is retinoprotective in a rodent model of retinitis pigmentosa. '''Sci R
    16 KB (2,064 words) - 08:21, 22 March 2024
  • SUIT-026 AmR ce-pce D087
    ...ion of [[digitonin]]. The protocol is focused on [[LEAK respiration|LEAK]] state for the [[S-pathway]] to provide the conditions of high membrane potential ...an Event&Mark for the uncoupler titration (4U) after ADP (3D) to obtain ET-state.
    4 KB (562 words) - 13:52, 31 August 2023
  • Mitchell 2011 Biochim Biophys Acta
    ...sume that the transition of the system from State 3, or its equivalent, to State 4, or its equivalent, occurs because the '''membrane potential''' builds up ...is not, however, likely to contribute significantly to the osmotic steady state of the mitochondria, because the rate of equilibration of water by diffusio
    6 KB (899 words) - 11:57, 9 May 2024
  • Hamilton 2016 Am J Physiol Heart Circ Physiol
    ...uced respiratory control ratios in subsarcolemmal mitochondria and reduced state 3 levels in interfibrillar mitochondria for complex I but not for complex I
    3 KB (410 words) - 17:18, 7 November 2016
  • Krako 2014 Abstract BBA - Bioenergetics
    ...ate accumulation points to the involvement of NO also in this pathological state, in agreement with the high activity of iNOS found in neurons affected by A
    3 KB (407 words) - 13:57, 27 March 2018
  • Koopman 2016 Nat Protoc
    ...an indicator of mitochondrial health. Seahorse XF96 respirometers are the state-of-the-art platform to assess respiration in cells, and we adapted the tech
    2 KB (286 words) - 00:58, 10 November 2023
  • Chung 2005 Am J Physiol Cell Physiol
    ...et of contraction and an ADP-dependent phase after Mb has reached a steady state. In contrast to the accepted view, the initial intracellular ''V''<sub>O<su
    2 KB (325 words) - 23:06, 15 July 2022
  • Christian 2019 Respir Physiol Neurobiol
    ...mitochondrial state 4). In following, the respiratory control ratio (RCR - state 3/state4) was calculated as an index of mitochondrial oxidative-phosphoryla
    3 KB (358 words) - 13:59, 12 June 2019
  • Maarman 2015 Abstract MiPschool Cape Town 2015
    hearts had a 21% lower RV state 2 (''p''< 0.02), 20% lower RV state 3 (''p''< 0.02), a 23% lower RV state 4 (''p''< 0.02) and unchanged RV RCI
    3 KB (496 words) - 13:15, 23 January 2019
  • Layec 2016 Am J Physiol Endocrinol Metab
    ...index of mitochondrial capacity, exhibited the strongest correlation with State 3 respiration (r = 0.80, P < 0.05). Therefore, this study reveals that each |keywords=PCr recovery, State 3 respiration, Mitochondrial capacity assessment, Respirometry
    3 KB (358 words) - 09:13, 8 November 2016
  • Moreno-Sanchez 2022 MitoFit
    ...espiratory fluxes were analyzed in cancer and non-cancer cells. The steady-state fluxes in energy metabolism were used to estimate the aerobic glycolytic an
    3 KB (461 words) - 07:50, 8 January 2023
  • US AL Birmingham Moellering DR
    |state=Alabama (AL)
    907 bytes (122 words) - 08:57, 11 May 2018
  • Hsu 2014 J Neurosci
    ...habenula in the regulation of voluntary activity, motor function, hedonic state, and primary reinforcement. J Neurosci 34:11366-84. ...the dMHb is involved in exercise motivation and the regulation of hedonic state, and is part of an intrinsic reinforcement circuit.
    2 KB (290 words) - 12:48, 9 March 2015
  • Bioblast-references
    ...tes and respiratory control in mouse and beef heart mitochondria at steady-state levels of hypoxia. J Appl Physiol 119:1210-8. - [[Harrison 2015 J Appl Phys
    15 KB (2,011 words) - 20:19, 1 January 2021
  • Le 2013 Thesis Colorado State University - Fort Collins
    ...deling on mitochondrial respiratory function in the heart. Thesis Colorado State University - Fort Collins:89 pp. |journal=Thesis Colorado State University - Fort Collins
    4 KB (492 words) - 09:13, 8 November 2016
  • MiPNet21.06 SUIT RP
    ...the use of digitonin we can address different [[Electron-transfer-pathway state]]s.
    7 KB (976 words) - 10:52, 2 September 2022
  • Ben-Shachar 2009 J Neural Transm (Vienna)
    ...y, are discussed. Among them are schizophrenia specific as well as disease-state-specific alterations in complex I activity in the peripheral tissue, which
    2 KB (317 words) - 12:47, 19 December 2023
  • King 2016 Redox Biol
    ...n of the mitochondrial permeability transition (MPT) pore, and the hypoxic state of the liver. ...SAM supplementation prevented alcohol-mediated decreases in mitochondrial state 3 respiration and cytochrome c oxidase activity. Mitochondria isolated from
    3 KB (380 words) - 12:09, 8 November 2016
  • Astrakhanova 2018 Sovrem Tekhnologii Med
    ...a МV (2018) BDNF-mediated regulation of the brain mitochondria functional state in hypoxia. Sovrem Tekhnologii Med 10:88-94.
    2 KB (270 words) - 14:49, 5 December 2019
  • Thaher 2017 Neurochem Int
    ...t mutation of this cysteine which forms disulphide bridges in an oxidative state, apparently renders MFN2 more susceptible to alterations of the redox envir
    2 KB (351 words) - 15:08, 11 October 2018
  • Stride 2013 Eur J Heart Fail
    ...sociated with a shift in substrate utilization and a compromised energetic state. Whether these changes are connected with mitochondrial dysfunction is not ...A oxidation. This offers a candidate mechanism for a compromised energetic state and decreased reliance on fatty acid utilization in HF.
    3 KB (371 words) - 15:45, 5 March 2019
  • Kudin 1999 Brain Res Brain Res Protoc
    ...olution respirometry adapted for slice measurements and measured the redox state of mitochondrial NAD(P)H in single hippocampal slices by laser-excited fluo
    1 KB (167 words) - 15:14, 13 February 2015
  • Trumbeckaite 2013 Mitochondrion
    ...D/reperfusion reduced the glutamate/malate dependent (and protein-related) state 3 respiration to 30% of its value under control conditions. All of the abov
    2 KB (256 words) - 16:19, 13 November 2017
  • Su 2021 Chin J Physiol
    ...reased the respiration rates of mitochondrial respiratory complex I and IV state 3, thereby improved myocardial mitochondrial respiratory function and energ
    3 KB (427 words) - 09:15, 16 August 2021
  • Blacker 2016 Free Radic Biol Med
    |title=Blacker TS, Duchen MR (2016) Investigating mitochondrial redox state using NADH and NADPH autofluorescence. Free Radic Biol Med 100:53-65. ...modern implementation of these techniques for studying mitochondrial redox state in complex tissue preparations. As the fluorescence spectra of NADH and NAD
    2 KB (292 words) - 17:11, 1 February 2022
  • White 2018 J Anim Sci
    ...affected by temperament, intrinsic (relative to CS activity) mitochondrial state 3 oxidative phosphorylation capacity with complex I substrates (P<sub>CI</s
    3 KB (464 words) - 06:59, 7 May 2020
  • Correa 2017 Crit Care
    ...≥10% group (p = 0.047). Complexes I and II maximal (state 3) and resting (state 4) isolated brain mitochondrial respiration at study end was higher in the
    3 KB (454 words) - 09:58, 12 June 2018
  • Kudin 2004 J Biol Chem
    |topics=Redox state
    3 KB (399 words) - 21:39, 13 April 2022
  • Kalinina 2016 J Biophotonics
    ...time of NAD(P)H which was a clear indication of acute changes in the redox state of the cells. For the first time simultaneous FLIM/PLIM has been shown to b ...s=FLIM, NAD(P)H, PLIM, Antimycin A, Cell metabolism, Oxygen tension, Redox state, Respiratory chain
    2 KB (328 words) - 11:57, 9 November 2016
  • SUIT-026 O2 ce-pce D088
    ...an Event&Mark for the uncoupler titration (4U) after ADP (3D) to obtain ET-state.
    2 KB (296 words) - 12:04, 5 September 2022
  • Piell K
    |state=Kentucky (KY)
    725 bytes (92 words) - 17:20, 31 October 2013
  • Ye 2013 Anal Biochem
    ...f these combined substrates, as well as through Complex IV. In protocol 2, state 3 rates are measured using palmitoylcarnitine to monitor fatty acid oxidati |keywords=Diagnosis; Systemic mitochondrial disease; Duroquinol oxidation; State 3 oxidation; Palmitoylcarnitine oxidation
    2 KB (278 words) - 15:50, 4 June 2022
  • Matallo 2014 Nitric Oxide
    ...ed after 3.5 [0.3;3.5] and 11.7 [6.2;21.2]min in the uncoupled and coupled state, respectively. This time was statistically significantly shorter when compa
    3 KB (388 words) - 15:16, 13 November 2017
  • Siebels 2013 Biochim Biophys Acta
    ...ced by the Q-site inhibitor atpenin A5 was largely unaffected by the redox state of the Q pool and the activity of other respiratory chain complexes. Hence,
    2 KB (278 words) - 10:39, 27 March 2018
  • MacDonald 2011 Am J Physiol Cell Physiol
    ...docardial and subepicardial layers was depressed and showed elevated leak (state 2) respiration. These data provide evidence that mitochondrial dysfunction
    3 KB (384 words) - 11:11, 23 January 2019
  • Park 2010 Sensors and Actuators B
    ...154.05±1.87 nA at the full-oxygen state and 2.77±1.0 nA at the zero-oxygen state. The fabricated sensor was used to measure the uncoupled OCR of the L6 cell ...154.05±1.87 nA at the full-oxygen state and 2.77±1.0 nA at the zero-oxygen state. The fabricated sensor was used to measure the uncoupled OCR of the L6 cell
    3 KB (376 words) - 17:25, 25 February 2020
  • Eaton 2002 Prog Lipid Res
    ...lonyl-CoA in vivo. beta-Oxidation flux can also be controlled by the redox state of NAD/NADH and ETF/ETFH(2). Control by [acetyl-CoA]/[CoASH] may also be si
    1 KB (190 words) - 12:06, 6 July 2021
  • Kraunsoee 2010 J Physiol
    ...ller. Robust, stable oxygen fluxes were found in both tissues, and coupled State 3 (GMOctS(D)) and non-coupled respiration were significantly (''P'' < 0.05)
    3 KB (382 words) - 15:43, 5 March 2019

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