Template:Keywords: Coupling control: Difference between revisions
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::: <span style="font-size:105%; color:##424242"> '''Bioblast links: Coupling control''' - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>></span> | ::: <span style="font-size:105%; color:##424242"> '''Bioblast links: Coupling control''' - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>></span> | ||
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== Mitochondrial and cellular respiratory rates in coupling control states == | == Mitochondrial and cellular respiratory rates in coupling control states == | ||
:::: [[File:P.jpg |link=OXPHOS-capacity]] [[OXPHOS-capacity]] ''P'' = ''Pยด''-''Rox'' | :::: [[File:P.jpg |link=OXPHOS-capacity]] [[OXPHOS-capacity]] ''P'' = ''Pยด''-''Rox'' |
Revision as of 04:44, 9 November 2020
4-compartmental OXPHOS model. (1) ET capacity E of the noncoupled electron transfer system ETS. OXPHOS capacity P is partitioned into (2) the dissipative LEAK component L, and (3) ADP-stimulated P-L net OXPHOS capacity. (4) If P-L is kinetically limited by a low capacity of the phosphorylation system to utilize the protonmotive force pmF, then the apparent E-P excess capacity is available to drive coupled processes other than phosphorylation Pยป (ADP to ATP) without competing with Pยป.
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Mitochondrial and cellular respiratory rates in coupling control states
- OXPHOS-capacity P = Pยด-Rox
- ROUTINE-respiration R = Rยด-Rox
- ET-capacity E = Eยด-Rox
- LEAK-respiration L = Lยด-Rox
- ยป LEAK-state with ATP
- ยป LEAK-state with oligomycin
- ยป LEAK-state without adenylates
- L/P coupling control ratio, L/P
- ยป RCR = P/L
- L/R coupling control ratio, L/R
- LEAK-control ratio, L/E
- ยป UCR = E/L
- OXPHOS-control ratio, P/E
- ROUTINE-control ratio, R/E
- L/P coupling control ratio, L/P
- Net OXPHOS-control ratio, (P-L)/E
- Net ROUTINE-control ratio, (R-L)/E
Net, excess, and reserve capacities of respiration
- Net OXPHOS-capacity P-L, P-L
- Net ROUTINE-activity R-L, R-L
- Net ET-capacity E-L, E-L
- ET-excess capacity E-P, E-P
- OXPHOS-coupling efficiency P-L, jP-L = (P-L)/P = 1-L/P
- ROUTINE-coupling efficiency R-L, jR-L = (R-L)/R = 1-L/R
- ET-coupling efficiency E-L, jE-L = (E-L)/E = 1-L/E
- ET-excess control efficiency E-P, jE-P = (E-P)/E = 1-P/E
- ET-reserve control efficiency E-R, jE-R = (E-R)/E = 1-R/E
General
- ยป Basal respiration
- ยป Baseline state
- ยป Dyscoupled respiration
- ยป Dyscoupling
- ยป Electron leak
- ยป ET-coupling efficiency
- ยป Flux control efficiency jZ-Y
- ยป Flux control ratio
- ยป Oxidative phosphorylation
- ยป Oxygen flow
- ยป Oxygen flux
- ยป Permeabilized cells
- ยป Phosphorylation system
- ยป Proton leak
- ยป Proton slip
- ยป Respiratory acceptor control ratio RCR
- ยป Respiratory state
- ยป Static head
- ยป Uncoupling