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|info=[[Gnaiger 2009 Int J Biochem Cell Biol|Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. Int J Biochem Cell Biol 41:1837-45.]] | |info=[[Gnaiger 2009 Int J Biochem Cell Biol|Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. Int J Biochem Cell Biol 41:1837-45.]] | ||
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{{MitoPedia | {{MitoPedia concepts | ||
|mitopedia | |mitopedia concept=MiP concept | ||
}} | }} | ||
__TOC__ | __TOC__ | ||
== MiPMap labels == | == MiPMap labels == | ||
'''MiPMap labels''' provide the backbone of the MiPMap project. The MiPMap labels can be considered as keywords which can be attached to various sources of information (publications). With proper labelling, multidimensional maps of information can be constructed, filtering the sources through various grids. | :::: '''MiPMap labels''' provide the backbone of the MiPMap project. The MiPMap labels can be considered as keywords which can be attached to various sources of information (publications). With proper labelling, multidimensional maps of information can be constructed, filtering the sources through various grids. | ||
The MiPMap labels (filters) are grouped into various topics (properties). | :::: The MiPMap labels (filters) are grouped into various topics (properties). | ||
=== MiP areas === | === MiP areas === | ||
: [[Property:MiP area]] | ::: [[Property:MiP area]] | ||
: β’β’ Respiration β’β’ Instruments;methods β’β’ mt-Biogenesis;mt-density β’β’ mt-Structure;fission;fusion β’β’ mt-Membrane β’β’ mtDNA;mt-genetics β’β’ nDNA;cell genetics β’β’ Genetic knockout;overexpression β’β’ Comparative MiP;environmental MiP β’β’ Gender β’β’ Developmental biology β’β’ Exercise physiology;nutrition;life style β’β’ mt-Medicine β’β’ Patients β’β’ Pharmacology;toxicology β’β’ mt-Awareness | :::: β’β’ Respiration β’β’ Instruments;methods β’β’ mt-Biogenesis;mt-density β’β’ mt-Structure;fission;fusion β’β’ mt-Membrane β’β’ mtDNA;mt-genetics β’β’ nDNA;cell genetics β’β’ Genetic knockout;overexpression β’β’ Comparative MiP;environmental MiP β’β’ Gender β’β’ Developmental biology β’β’ Exercise physiology;nutrition;life style β’β’ mt-Medicine β’β’ Patients β’β’ Pharmacology;toxicology β’β’ mt-Awareness | ||
::::* Patients: when there is real information about patients, not just whenever a pathology is dealt with | |||
: | |||
: | |||
=== | === Organism === | ||
: [[Property: | ::: [[Property:Mammal and model]] | ||
: β’β’ Birds β’β’ Reptiles β’β’ Amphibians β’β’ Fishes β’β’ Chelicerates β’β’ Crustaceans β’β’ Hexapods β’β’ Myriapods β’β’ Annelids β’β’ Molluscs β’β’ Nematodes β’β’ Other invertebrates | ::::: β’β’ Human β’β’ Pig β’β’ Mouse β’β’ Rat β’β’ Guinea pig β’β’ Bovines β’β’ Horse β’β’ Dog β’β’ Rabbit β’β’ Cat β’β’ Other mammals β’β’ Chicken β’β’ Zebrafish β’β’ Drosophila β’β’ Artemia β’β’ Caenorhabditis elegans β’β’ Saccharomyces cerevisiae β’β’ Birds β’β’ Reptiles β’β’ Amphibians β’β’ Fishes β’β’ Chelicerates β’β’ Crustaceans β’β’ Hexapods β’β’ Myriapods β’β’ Annelids β’β’ Molluscs β’β’ Nematodes β’β’ Other invertebrates β’β’ Fungi β’β’ Plants β’β’ Protists β’β’ β’β’ Eubacteria β’β’ Archea | ||
=== Tissues;cellsΒ === | === Tissues;cellsΒ === | ||
: [[Property:Tissue and cell]] | ::: [[Property:Tissue and cell]] | ||
: β’β’ Heart β’β’ Skeletal muscle β’β’ Nervous system β’β’ Liver β’β’ Kidney β’β’ Lung;gill β’β’ Islet Cell; Pancreas; Thymus β’β’ Endothelial; Epithelial; Mesothelial Cell β’β’ Blood cells β’β’ Fat β’β’ | :::: β’β’ Heart β’β’ Skeletal muscle β’β’ Nervous system β’β’ Liver β’β’ Kidney β’β’ Lung;gill β’β’ Islet Cell; Pancreas; Thymus β’β’ Endothelial; Epithelial; Mesothelial Cell β’β’ Blood cells β’β’ Fat β’β’ Genital β’β’Β Other cell lines β’β’ CHO β’β’ HEK β’β’ HeLa β’β’ Neuroblastoma β’β’ Fibroblast β’β’ HUVEC β’β’ Macrophage-derived stem cells β’β’ Lymphocyte β’β’ Platelet β’β’ Stem cells | ||
Β | |||
=== Preparations === | === Preparations === | ||
: [[Property:Preparation]] | ::: [[Property:Preparation]] | ||
: β’β’ Intact Organism β’β’ Intact Organ β’β’ Intact cells β’β’ Permeabilized cells β’β’ Permeabilized tissue β’β’ Homogenate β’β’ Isolated Mitochondria β’β’ SMP β’β’ Chloroplasts β’β’ Enzyme β’β’ Oxidase; Biochemical Oxidation | :::: β’β’ Intact Organism β’β’ Intact Organ β’β’ Intact cells β’β’ Permeabilized cells β’β’ Permeabilized tissue β’β’ Homogenate β’β’ Isolated Mitochondria β’β’ SMP β’β’ Chloroplasts β’β’ Enzyme β’β’ Oxidase; Biochemical Oxidation | ||
=== Enzymes === | === Enzymes === | ||
: [[Property:Enzyme]] | ::: [[Property:Enzyme]] | ||
: β’β’ Adenine Nucleotide Translocase β’β’ Complex I β’β’ Complex II; Succinate Dehydrogenase β’β’ Complex III β’β’ Complex IV; Cytochrome c Oxidase β’β’ Complex V; ATP Synthase β’β’ Inner mtMembrane Transporter β’β’ Marker Enzyme β’β’ Supercomplex β’β’ TCA Cycle and Matrix Dehydrogenases β’β’ Uncoupling protein | :::: β’β’ Adenine Nucleotide Translocase β’β’ Complex I β’β’ Complex II; Succinate Dehydrogenase β’β’ Complex III β’β’ Complex IV; Cytochrome c Oxidase β’β’ Complex V; ATP Synthase β’β’ Inner mtMembrane Transporter β’β’ Marker Enzyme β’β’ Supercomplex β’β’ TCA Cycle and Matrix Dehydrogenases β’β’ Uncoupling protein | ||
=== Stress conditions === | === Stress conditions === | ||
: [[Property:Stress]] | ::: [[Property:Stress]] | ||
: β’β’ Cell death β’β’ Cryopreservation β’β’ Ischemia-reperfusion β’β’ Permeability transition β’β’ Oxidative stress;RONS | :::: β’β’ Cell death β’β’ Cryopreservation β’β’ Ischemia-reperfusion β’β’ Permeability transition β’β’ Oxidative stress;RONS β’β’ Hypothermia; hyperthermia β’β’ Mitochondrial desease | ||
=== Pathological states === | === Pathological states === | ||
: [[Property:Diseases]] | ::: [[Property:Diseases]] | ||
: β’β’ Aging; senescence β’β’ Alzheimer's β’β’ Autism β’β’ Cancer β’β’ Cardiovascular β’β’ COPD β’β’ Diabetes β’β’ Inherited β’β’ Infectious β’β’ | :::: β’β’ Aging; senescence β’β’ Alzheimer's β’β’ Autism β’β’ Cancer β’β’ Cardiovascular β’β’ COPD β’β’ Diabetes β’β’ Inherited β’β’ Infectious β’β’ Myopathy β’β’ Neurodegenerative β’β’ Obesity β’β’ Parkinson's β’β’ Sepsis β’β’ OtherΒ Β Β | ||
=== Regulation;kinetics === | === Regulation;kinetics === | ||
: [[Property:Respiration and regulation]] | ::: [[Property:Respiration and regulation]] | ||
: β’β’ Aerobic glycolysis β’β’ ADP | :::: β’β’ Aerobic glycolysis β’β’ ADP β’β’ ATP β’β’ ATP production β’β’ Calcium β’β’ Coupling efficiency;uncoupling β’β’ Cyt c β’β’ Flux control β’β’ Inhibitor β’β’ Ion;substrate transport β’β’ mt-Membrane potential β’β’ Oxygen kinetics β’β’ PCr;Cr β’β’ pH β’β’ Phosphate β’β’ Redox state β’β’ Substrate β’β’ Temperature β’β’ Threshold;excess capacity β’β’ Uncoupler β’β’ Fatty acid β’β’ Amino acid | ||
* Oxygen: Oxygen kinetics, oxygen dependence of respiration and mitochondrial processes | ::::* Oxygen: Oxygen kinetics, oxygen dependence of respiration and mitochondrial processes | ||
Β Β | Β Β | ||
=== Coupling states === | === Coupling control states === | ||
: [[Property:Coupling states]] | ::: [[Property:Coupling states]] | ||
: β’β’ LEAK β’β’ ROUTINE β’β’ OXPHOS β’β’ | :::: β’β’ LEAK β’β’ ROUTINE β’β’ OXPHOS β’β’ ET-pathway | ||
=== | === Pathway control states === | ||
: [[Property: | ::: [[Property:Pathways]] | ||
: β’β’ | :::: β’β’ F β’β’ N β’β’ S β’β’ Gp β’β’ DQ β’β’ CIV β’β’ NS β’β’ Other combinations β’β’ ROXΒ Β Β | ||
=== High-resolution respirometry - HRR === Β | === High-resolution respirometry - HRR === Β | ||
: [[Property:Instrument and method]] | ::: [[Property:Instrument and method]] | ||
: β’β’ High-resolution respirometry: Oxygraph-2k β’β’ TIP2k β’β’ O2k-Fluorometer β’β’ pH β’β’ NO β’β’ TPP β’β’ Ca β’β’ O2k-Spectrophotometer β’β’ O2k-Manual β’β’ Protocol β’β’ Theory | :::: β’β’ High-resolution respirometry: Oxygraph-2k β’β’ TIP2k β’β’ O2k-Fluorometer β’β’ pH β’β’ NO β’β’ TPP β’β’ Ca β’β’ O2k-Spectrophotometer β’β’ O2k-Manual β’β’ O2k-Protocol β’β’ Theory | ||
=== Additional labels === Β | === Additional labels === Β | ||
: β’β’ Β | ::: β’β’ Β | ||
::::* Made history: [[Mitochondria and bioblasts: Made history]]. | |||
:::* Labels: indicates that publication has been entered but not yet labelled or that labelling might need revision. | |||
::::* noPDF: no PDF was available for the implementation of this publication; labelling is merely based on the abstract. | |||
::::* [Epub ahead of print] helps in finding and complementing references with no available issue and page numbers at the time of implementation. | |||
::::* MitoFitPublication: To label publications affiliated with the MitoFit project. | |||
::::* Date in the format yyyy-mm, e.g. 2015-12: indicates the year and month the publication was implemented and helps in creating the table of recently added Publications. | |||
[[File:Bioblast-publications.jpg|left|80px]] | |||
== Publications in the MiPMap == | |||
=== Mitochondrial properties in organisms (species), cell types and tissues === | |||
::::* [[Special:BrowseData/Publications|Browse publications using MiPMap filters]] | |||
::::* [[O2k-Publications: Topics]] | |||
=== Journals === | |||
== | ::::* [[Journals in Bioblast]] | ||
* [[ | |||
== Initiation == | == Initiation == | ||
* Presented at [[Bioblast 2012]]. | ::::* Presented at [[Bioblast 2012]]. | ||
* Focus for [ | ::::* Focus for [[MiP2013|MiP''conference'' on Comparative Mitochondrial Physiology]] | ||
* [[MiP2013 Abstracts]] | ::::* [[MiP2013 Abstracts]] | ||
* Link to [[ | ::::* Link to [[MitoGlobal]] | ||
[[Category:MitoPedia]] | [[Category:MitoPedia]] | ||
[[Category:MitoFit]] | |||
[[Category:Mitochondrial Global Network]] | [[Category:Mitochondrial Global Network]] | ||
[[Category:EAGLE]] | [[Category:EAGLE]] | ||
{{Gentle Science}} | {{Gentle Science}} |
Latest revision as of 11:14, 20 October 2017
Description
The project Mitochondrial Physiology Map (MiPMap) is initiated to provide an overview of mitochondrial properties in cell types, tissues and species. As part of Bioblast, MiPMap may be considered as an information synthase for Comparative Mitochondrial Physiology. Establishing a comprehensive database will require global input and cooperation.
A comparative database of mitochondrial physiology may provide the key for understanding the functional implications of mitochondrial diversity from mouse to man, and evaluation of altered mitochondrial respiratory control patterns in health and disease (Gnaiger 2009).
Abbreviation: MiPMap
MitoPedia concepts:
MiP concept
MiPMap labels
- MiPMap labels provide the backbone of the MiPMap project. The MiPMap labels can be considered as keywords which can be attached to various sources of information (publications). With proper labelling, multidimensional maps of information can be constructed, filtering the sources through various grids.
- The MiPMap labels (filters) are grouped into various topics (properties).
MiP areas
- Property:MiP area
- β’β’ Respiration β’β’ Instruments;methods β’β’ mt-Biogenesis;mt-density β’β’ mt-Structure;fission;fusion β’β’ mt-Membrane β’β’ mtDNA;mt-genetics β’β’ nDNA;cell genetics β’β’ Genetic knockout;overexpression β’β’ Comparative MiP;environmental MiP β’β’ Gender β’β’ Developmental biology β’β’ Exercise physiology;nutrition;life style β’β’ mt-Medicine β’β’ Patients β’β’ Pharmacology;toxicology β’β’ mt-Awareness
- Property:MiP area
- Patients: when there is real information about patients, not just whenever a pathology is dealt with
Organism
- Property:Mammal and model
- β’β’ Human β’β’ Pig β’β’ Mouse β’β’ Rat β’β’ Guinea pig β’β’ Bovines β’β’ Horse β’β’ Dog β’β’ Rabbit β’β’ Cat β’β’ Other mammals β’β’ Chicken β’β’ Zebrafish β’β’ Drosophila β’β’ Artemia β’β’ Caenorhabditis elegans β’β’ Saccharomyces cerevisiae β’β’ Birds β’β’ Reptiles β’β’ Amphibians β’β’ Fishes β’β’ Chelicerates β’β’ Crustaceans β’β’ Hexapods β’β’ Myriapods β’β’ Annelids β’β’ Molluscs β’β’ Nematodes β’β’ Other invertebrates β’β’ Fungi β’β’ Plants β’β’ Protists β’β’ β’β’ Eubacteria β’β’ Archea
- Property:Mammal and model
Tissues;cells
- Property:Tissue and cell
- β’β’ Heart β’β’ Skeletal muscle β’β’ Nervous system β’β’ Liver β’β’ Kidney β’β’ Lung;gill β’β’ Islet Cell; Pancreas; Thymus β’β’ Endothelial; Epithelial; Mesothelial Cell β’β’ Blood cells β’β’ Fat β’β’ Genital β’β’ Other cell lines β’β’ CHO β’β’ HEK β’β’ HeLa β’β’ Neuroblastoma β’β’ Fibroblast β’β’ HUVEC β’β’ Macrophage-derived stem cells β’β’ Lymphocyte β’β’ Platelet β’β’ Stem cells
- Property:Tissue and cell
Preparations
- Property:Preparation
- β’β’ Intact Organism β’β’ Intact Organ β’β’ Intact cells β’β’ Permeabilized cells β’β’ Permeabilized tissue β’β’ Homogenate β’β’ Isolated Mitochondria β’β’ SMP β’β’ Chloroplasts β’β’ Enzyme β’β’ Oxidase; Biochemical Oxidation
- Property:Preparation
Enzymes
- Property:Enzyme
- β’β’ Adenine Nucleotide Translocase β’β’ Complex I β’β’ Complex II; Succinate Dehydrogenase β’β’ Complex III β’β’ Complex IV; Cytochrome c Oxidase β’β’ Complex V; ATP Synthase β’β’ Inner mtMembrane Transporter β’β’ Marker Enzyme β’β’ Supercomplex β’β’ TCA Cycle and Matrix Dehydrogenases β’β’ Uncoupling protein
- Property:Enzyme
Stress conditions
- Property:Stress
- β’β’ Cell death β’β’ Cryopreservation β’β’ Ischemia-reperfusion β’β’ Permeability transition β’β’ Oxidative stress;RONS β’β’ Hypothermia; hyperthermia β’β’ Mitochondrial desease
- Property:Stress
Pathological states
- Property:Diseases
- β’β’ Aging; senescence β’β’ Alzheimer's β’β’ Autism β’β’ Cancer β’β’ Cardiovascular β’β’ COPD β’β’ Diabetes β’β’ Inherited β’β’ Infectious β’β’ Myopathy β’β’ Neurodegenerative β’β’ Obesity β’β’ Parkinson's β’β’ Sepsis β’β’ Other
- Property:Diseases
Regulation;kinetics
- Property:Respiration and regulation
- β’β’ Aerobic glycolysis β’β’ ADP β’β’ ATP β’β’ ATP production β’β’ Calcium β’β’ Coupling efficiency;uncoupling β’β’ Cyt c β’β’ Flux control β’β’ Inhibitor β’β’ Ion;substrate transport β’β’ mt-Membrane potential β’β’ Oxygen kinetics β’β’ PCr;Cr β’β’ pH β’β’ Phosphate β’β’ Redox state β’β’ Substrate β’β’ Temperature β’β’ Threshold;excess capacity β’β’ Uncoupler β’β’ Fatty acid β’β’ Amino acid
- Property:Respiration and regulation
- Oxygen: Oxygen kinetics, oxygen dependence of respiration and mitochondrial processes
Coupling control states
- Property:Coupling states
- β’β’ LEAK β’β’ ROUTINE β’β’ OXPHOS β’β’ ET-pathway
- Property:Coupling states
Pathway control states
- Property:Pathways
- β’β’ F β’β’ N β’β’ S β’β’ Gp β’β’ DQ β’β’ CIV β’β’ NS β’β’ Other combinations β’β’ ROX
- Property:Pathways
High-resolution respirometry - HRR
- Property:Instrument and method
- β’β’ High-resolution respirometry: Oxygraph-2k β’β’ TIP2k β’β’ O2k-Fluorometer β’β’ pH β’β’ NO β’β’ TPP β’β’ Ca β’β’ O2k-Spectrophotometer β’β’ O2k-Manual β’β’ O2k-Protocol β’β’ Theory
- Property:Instrument and method
Additional labels
- β’β’
- Made history: Mitochondria and bioblasts: Made history.
- Labels: indicates that publication has been entered but not yet labelled or that labelling might need revision.
- noPDF: no PDF was available for the implementation of this publication; labelling is merely based on the abstract.
- [Epub ahead of print] helps in finding and complementing references with no available issue and page numbers at the time of implementation.
- MitoFitPublication: To label publications affiliated with the MitoFit project.
- Date in the format yyyy-mm, e.g. 2015-12: indicates the year and month the publication was implemented and helps in creating the table of recently added Publications.
- β’β’
Publications in the MiPMap
Mitochondrial properties in organisms (species), cell types and tissues
Journals
Initiation
- Presented at Bioblast 2012.
- Focus for MiPconference on Comparative Mitochondrial Physiology
- MiP2013 Abstracts
- Link to MitoGlobal