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A list of all pages that have property "Description" with value "'''Ca<sup>2+</sup>''' is a major signaling molecule in both prokaryotes". Since there have been only a few results, also nearby values are displayed.

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  • Biopsy preservation solution  + ('''Biopsy preservation solution''', for preservation of tissue samples, preparation of muscle fibres, and permeabilization with [[saponin]].)
  • Blebbistatin  + ('''Blebbistatin''' is a widely used muscle'''Blebbistatin''' is a widely used muscle and non-muscle myosin II-specific inhibitor that block contractile activity. Blebbistatin shows selectivity and high affinity for multiple class II myosins. Blebbistatin is commonly employed in respirometric experiments with permeabilized muscle fibers (pfi). Permeabilized muscle fibers are sensitive to low oxygen supply due to diffusion restrictions that limit mitochondrial respiration at the core of the fiber bundle. Therefore, hyperoxic conditions are required to counteract this limitation. Further studies have shown that the addition of blebbistatin in the respiration medium prevents fiber contraction, reduces the oxygen sensitivity and allows the study of ADP kinetics in pfi at normoxic oxygen levels. However, other studies described that the presence of blebbistatin does not prevent the oxygen dependence in pfi. Moreover, several limitations of blebbistatin i.e. low solubility in water, cytotoxicity and phototoxicity have been described.ity and phototoxicity have been described.)
  • Blood cell preparation  + ('''Blood cell preparation''' (bcp) is one of the key steps in diagnostic protocols.)
  • Blood plasma  + ('''Blood plasma''' is the non-cellular com'''Blood plasma''' is the non-cellular component of the blood. Plasma lacks cellular components of the blood, [[red blood cell]]s, [[white blood cell]]s, and [[platelet]]s. However, there are many proteins in plasma, i.e. fibrinogen, albumin and globulin. Both blood plasma and [[platelet-rich plasma]] maintain clotting activity after whole blood separation.ing activity after whole blood separation.)
  • Blood serum  + ('''Blood serum''' is a purified plasma in '''Blood serum''' is a purified plasma in which the coagulant components were removed from the [[blood plasma]]. It contains other substances, i.e. antibodies, antigens and hormones. Serum can be obtained by collecting the liquid phase after blood or plasma coagulation.d phase after blood or plasma coagulation.)
  • Bongkrekik acid  + ('''Bongkrekik acid''' is a selective and potent inhibitor of the [[adenine nucleotide translocator]] (ANT). Bka binds to the matrix (negative) site of ANT, opposite of [[carboxyatractyloside]].)
  • CE  + ('''CE''' marking is a mandatory conformity marking for certain products sold within the European Economic Area (EEA).)
  • CHNO-fuel substrate  + ('''CHNO-fuel substrates''' are reduced car'''CHNO-fuel substrates''' are reduced carbon-hydrogen-nitrogen-oxygen substrates which are oxidized in the [[exergonic]] process of [[cell respiration]]. Mitochondrial pathways are stimulated by CHNO-fuel substrates feeding electrons into the [[ETS]] at different levels of integration and in the presence or absence of inhibitors acting on specific enzymes which are gate-keepers and control various pathway segments.pers and control various pathway segments.)
  • COPE core practices for research  + ('''COPE core practices for research''' are applicable to all involved in publishing scholarly literature.)
  • Calcium  + ('''Ca<sup>2+</sup>''' is a maj'''Ca<sup>2+</sup>''' is a major signaling molecule in both prokaryotes and eukaryotes. Its cytoplasmic concentration is tightly regulated by transporters in the plasma membrane and in the membranes of various organelles. For this purpose, it is either extruded from the cell through exchangers and pumps or stored in organelles such as the endoplasmic reticulum and the mitochondria. Changes in the concentration of the cation regulate numerous enzymes including many involved in ATP utilizing and in ATP generating pathways and thus ultimately control metabolic activity of mitochondria and of the entire cell. Measuring changes in Ca<sup>2+</sup> levels is thus of considerable interest in the context of [[high-resolution respirometry]].[[high-resolution respirometry]].)
 ('''Ca<sup>2+</sup>''' is a major signaling molecule in both prokaryotes)
  • Calcium Green  + ('''Calcium Green'''<sup>TM</sup&g'''Calcium Green'''<sup>TM</sup> (CaG) denotes a family of [[extrinsic fluorophores]] applied for measurement of Ca<sup>2+</sup> concentration with [[mitochondrial preparations]]. This dye fluoresces when bound to Ca<sup>2+</sup>. When measuring mitochondrial calcium uptake it is possible to observe the increase of the CaG signal upon calcium titration, followed by the decrease of CaG signal due to the uptake.n calcium titration, followed by the decrease of CaG signal due to the uptake.)
  • Calorespirometry  + ('''Calorespirometry''' is the method of me'''Calorespirometry''' is the method of measuring simultaneously metabolic heat flux ([[calorimetry]]) and oxygen flux ([[respirometry]]). The [[calorespirometric ratio]] (CR ratio; heat/oxygen flux ratio) is thus experimentally determined and can be compared with the theoretical [[oxycaloric equivalent]], as a test of the aerobic energy balance., as a test of the aerobic energy balance.)
  • Carbohydrate  + ('''Carbohydrates''', also known as '''sacc'''Carbohydrates''', also known as '''saccharides''', are molecules composed of carbon, hydrogen and oxygen. These molecules can be divided by size and complexity into monosaccharides, disaccharides, oligosaccharides, and polysaccharides. [[Glucose]] is a monosaccharide considered the primary source of energy in cells and a metabolic intermediate. This carbohydrate undergoes glycolysis, with the generation of [[pyruvate]], that can enter the [[TCA cycle]]. </br></br>Carbohydrates such as glucose and fructose may also be involved in the [[Crabtree effect]].[[Crabtree effect]].)
  • Carbonyl cyanide m-chlorophenyl hydrazone  + ('''Carbonyl cyanide m-chlorophenyl hydrazo'''Carbonyl cyanide m-chlorophenyl hydrazone''', CCCP (U; C<sub>9</sub>H<sub>5</sub>ClN<sub>4</sub>; ''F''<sub>W</sub> = 204.62) is a protonophore (H<sup>+</sup> ionophore) and is used as a potent chemical [[uncoupler]] of [[oxidative phosphorylation]]. Like all uncouplers, CCCP concentrations must be titrated carefully to evaluated the optimum concentration for maximum stimulation of mitochondrial respiration, particularly to avoid inhibition of respiration at higher CCCP concentrations.ochondrial respiration, particularly to avoid inhibition of respiration at higher CCCP concentrations.)
  • Carboxy SNARF 1  + ('''Carboxy SNARF® 1''' is a cell-impermean'''Carboxy SNARF® 1''' is a cell-impermeant pH indicator dye. The pKa of ~7.5 makes it useful for measuring pH in the range of pH 7 to pH 8. The emission shifts from yellow-orange at low pH to deep red fluorescence at high pH. Ratiometric fluorometry, therefore, is applied at two emission wavelengths,such as 580 nm and 640 nm.</br></br>Relative molecular mass: ''M''<sub>r</sub> = 453.45molecular mass: ''M''<sub>r</sub> = 453.45)
  • Carboxyatractyloside  + ('''Carboxyatractyloside''' CAT is a highly'''Carboxyatractyloside''' CAT is a highly selective and potent inhibitor of the [[adenine nucleotide translocator]] (ANT). CAT stabilizes the nucleoside binding site of ANT on the cytoplasmic (positive) side of the inner membrane and blocks the exchange of matrix ATP and cytoplasmic ADP. It causes stabilization of the ''c'' conformation of ANT leading to permeability transition pore (PTP) opening, loss of mitochondrial membrane potential, and apoptosis.ondrial membrane potential, and apoptosis.)
  • Cardiolipin  + ('''Cardiolipin''', CL, is a double phospho'''Cardiolipin''', CL, is a double phospholipid (having 4 fatty acyl chains) in the mitochondrial inner membrane (mtIM) which plays an important role in mitochondrial bioenergetics. CL is involved in the mitochondria-dependent pathway of apoptosis, participates in the function and stabilization of mitochondrial respiratory complexes and supercomplexes and also contributes to mitochondrial integrity.</br> Contributed by [[Sparagna G]] 2016-04-18[[Sparagna G]] 2016-04-18)
  • Carnitine O-octanoyltransferase  + ('''Carnitine O-octanoyltransferase''' is a mitochondrial enzyme that transfers [[carnitine]] to octanoyl-CoA to form [[Coenzyme A]] and [[octanoylcarnitine]]: Octanoyl-CoA + L-carnitine ↔ CoA + L-octanoylcarnitine.)
  • Carnitine acetyltransferase  + ('''Carnitine acetyltransferase''' (CrAT) i'''Carnitine acetyltransferase''' (CrAT) is located in the mitochondrial matrix and catalyses the formation of acetyl-carnitine from acetyl-CoA and L-carnitine and thus regulates the acetyl-CoA/free CoA ratio which is essential for [[pyruvate dehydrogenase]] complex (PDC) activity.[[pyruvate dehydrogenase]] complex (PDC) activity.)
  • Carnitine acyltransferase  + ('''Carnitine acyltransferases''' mediate t'''Carnitine acyltransferases''' mediate the transport of long-chain fatty acids across the inner mt-membrane by binding them to carnitine. First, long-chain fatty acids are activated by an energy-requiring step in which the fatty acid ester of CoA is formed enzymatically at the expense of ATP. The fatty acids then pass through the inner mt-membrane and enter the mitochondria as carnitine esters ([[acylcarnitine]]s). The fatty acyl group is then transferred from carnitine to intramitochondrial CoA and the resulting fatty acyl CoA is used as a substrate in the fatty acid oxidation (FAO) cycle in the mt-matrix.id oxidation (FAO) cycle in the mt-matrix.)
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