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• O2k-Publications: Sepsis
  ...Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Diseases::Sepsis]] == O2k-Publications: Sepsis - Abstracts ==
  1 KB (193 words) - 15:48, 16 April 2018

Page text matches

• Correa 2015 Critical Care Horizon
  |title=Corrêa TD, Jakob SM, Takala J (2015) Mitochondrial function in sepsis. Critical Care Horizon 1:31-41 . ...criticalcarehorizons.com/wp-content/uploads/2040/06/mitochondrial-function-sepsis-FINAL.pdf Open Access PDF]
  1 KB (202 words) - 16:06, 7 November 2016
• Jeger 2013 Eur J Clin Invest
  ...eger V, Djafarzadeh S, Jakob SM, Takala J (2013) Mitochondrial function in sepsis. Eur J Clin Invest 43:532-42. ...cused review evaluates the evidence for impaired mitochondrial function in sepsis.
  2 KB (305 words) - 15:46, 27 April 2015
• Eyenga 2022 Cells
  ...SS (2022) Regulation of oxidative phosphorylation of liver mitochondria in sepsis. Cells 11:1598. https://doi.org/10.3390/cells11101598 ...enues to improve the functions of cytochrome c oxidase and ATP synthase in sepsis.
  2 KB (236 words) - 23:20, 23 April 2023
• Kohoutova 2018 Physiol Res
  ..., Kuncová J (2018) Variability of mitochondrial respiration in relation to sepsis-induced multiple organ dysfunction. Physiol Res 67:577-92. ...d minimized by the use of appropriate experimental models resembling human sepsis, wider use of larger animal species in preclinical studies, more detailed m
  2 KB (290 words) - 16:03, 25 March 2019
• Frost S
  |topics=Hyperoxic sepsis, COLD sepsis
  634 bytes (76 words) - 15:26, 13 February 2018
• Jang 2018 Shock
  ...tions in mitochondrial function in blood cells obtained from patients with sepsis presenting to an emergency department. Shock 51:580-84. ...completely understood pathophysiology of the dysregulated host response in sepsis.
  2 KB (343 words) - 14:37, 5 July 2023
• Doerrier 2015 Thesis
  |title=Doerrier C (2015) Estudio bioenergetica mitochondrial en la sepsis experimental y efecto protector de la Melatonina. Doctoral Thesis p154. |abstract=Sepsis, a systemic inflammatory response of the organism against an infection,
  2 KB (326 words) - 15:11, 23 January 2019
• Horak 2020 Front Immunol
  ...engl M, Matejovic M (2020) Evaluation of mesenchymal stem cell therapy for sepsis: a randomized controlled porcine study. Front Immunol 11:126. ...n adequately studied in large-animal models with better relevance to human sepsis.
  3 KB (363 words) - 19:32, 14 February 2022
• Sims 2014 FASEB J
  ...P (2014) Mitochondrial superoxide generation in the rat pup kidney during sepsis. FASEB J 28:1063.7. ...the mitochondrial complexes at these early time points studied. Therefore, sepsis does not appear to cause severe mitochondrial dysfunction in rat pups despi
  2 KB (271 words) - 15:00, 28 March 2018
• O2k-Publications: Sepsis
  ...Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Diseases::Sepsis]] == O2k-Publications: Sepsis - Abstracts ==
  1 KB (193 words) - 15:48, 16 April 2018
• Ortiz 2014 J Pineal Res
  ...eficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of iNOS and preservation of nNOS. J Pineal Res 56:71-81. ...t during sepsis and further support the beneficial actions of melatonin in sepsis.
  2 KB (358 words) - 08:05, 21 February 2020
• Leduc-Gaudet 2021 bioRxiv
  ...D, Huck L, Sandri M, Gouspillou G, Hussain SNA (2021) Role of autophagy in sepsis-induced skeletal muscle dysfunction, whole-body metabolism, and survival. b ...mpacts survival. Induction of autophagy in skeletal muscles in response to sepsis thus represents a protective mechanism.
  3 KB (373 words) - 14:13, 27 October 2021
• Al-Obeidallah 2021 J Pers Med
  ...temperature allow early discrimination between porcine peritonitis-induced sepsis and peritonitis-induced septic shock. J Pers Med 11:164. ..., hemodynamical parameters and body temperature discriminate early between sepsis and septic shock in a clinically relevant porcine model. Early pronounced a
  2 KB (305 words) - 17:29, 8 March 2021
• Weiss 2022 Shock
  ...rial measurements in peripheral blood mononuclear cells from children with sepsis. Shock 57:630-8. https://doi.org/10.1097/SHK.0000000000001903 ...on PBMC mitochondrial respiration and content in children with and without sepsis.
  3 KB (403 words) - 22:49, 12 September 2023
• Doerrier 2014 Life Sci
  ...ata showed that melatonin maintains liver mitochondrial homeostasis during sepsis, but neither the mechanisms underlying mitochondrial dysfunction nor the ta ...C57BL/6 mice at early and late phases of sepsis, i.e., at 8 and 24 h after sepsis induction.
  3 KB (352 words) - 00:49, 10 February 2020
• Sjoevall 2013 Crit Care
  ...all F, Morota S, Persson J, Hansson Magnus J, Elmer E (2013) Patients with sepsis exhibit increased mitochondrial respiratory capacity in peripheral blood im ...ated mitochondrial respiration in peripheral blood immune cells (PBICs) in sepsis patients during the first week after admission to the intensive care unit (
  2 KB (331 words) - 23:09, 29 February 2020
• Jang 2019 Crit Care Med
  ...aion and mitochondrial function in blood cells obtained from patients with sepsis. Crit Care Med. ...and peripheral blood mononuclear cells (PBMCs) obtained from patients with sepsis and healthy controls.
  3 KB (459 words) - 14:37, 5 July 2023
• Patil 2014 Am J Physiol Renal Physiol
  ...ochondrial respiratory complexes and manganese superoxide dismutase during sepsis: mitochondria targeted antioxidant mitigates injury. Am J Physiol Renal Phy ...ased 96-hour survival rate from 40% in untreated septic mice to 80%. Thus, sepsis causes sustained inactivation of three mitochondrial targets that can lead
  2 KB (320 words) - 09:42, 8 November 2016
• Larche 2006 J Am Coll Cardiol
  ...ere R (2006) Inhibition of mitochondrial permeability transition prevents sepsis-induced myocardial dysfunction and mortality. J Am Coll Cardiol 48:377-85. ...dysfunction is causative of sepsis sequelae, a mouse model of peritonitis sepsis induced by cecal ligation and perforation. Inhibition of mitochondrial perm
  3 KB (360 words) - 11:50, 22 December 2020
• Doerrier 2016 Mitochondrion
  ...ized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochon ...o identify properly respiratory deficits and specific melatonin effects in sepsis.
  2 KB (272 words) - 04:35, 19 July 2022
• Manfredini 2019 Clin Sci (Lond)
  ...dysfunction is associated with long-term cognitive impairment in an animal sepsis model. Clin Sci (Lond) 133:1993-2004. ...al function and long-term cognitive impairment in an experimental model of sepsis.
  3 KB (360 words) - 16:59, 13 May 2020
• Zhang 2018 Mil Med Res
  ...(2018) Potential therapy strategy: targeting mitochondrial dysfunction in sepsis. Mil Med Res 5:41. https://doi.org/10.1186/s40779-018-0187-0 ...etermine the major mitochondrial disorders from morphology to functions in sepsis. In the following, several clinical or pre-clinical assays for monitoring m
  2 KB (289 words) - 11:08, 22 March 2023
• Kohoutova 2019 Crit Care Med
  ...attenuates multiple organ dysfunction in resuscitated porcine progressive sepsis. Crit Care Med 47:e461-69. ...rve stimulation in a clinically-relevant large animal model of progressive sepsis.
  3 KB (355 words) - 19:42, 17 February 2022
• Volt 2014 Abstract The 2014 Ageing Summit
  ...in on the age-dependent dysregulation of the Nf-Kb/Nlrp3 activation during sepsis. ...s support NLRP3 inflammasome as a novel molecular signaling pathway during sepsis and indentify it as a main target for the anti-inflammatory action of melat
  2 KB (288 words) - 17:34, 7 November 2016
• Cheng 2016 Nat Immunol
  ...defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis. Nat Immunol 17:406-13. ...suggested that metabolic processes might represent a therapeutic target in sepsis.
  2 KB (303 words) - 04:13, 12 February 2020
• Weiss 2021 Crit Care Explor
  ..., Collman RG (2021) Decreased intestinal microbiome diversity in pediatric sepsis: a conceptual framework for intestinal dysbiosis to influence immunometabol ...ain fatty acids. We explored whether intestinal dysbiosis in children with sepsis leads to changes in microbial-derived short-chain fatty acids in plasma and
  3 KB (418 words) - 09:31, 9 July 2021
• Loftus 2017 BMJ Open
  ...tocols and standard operating procedures for a prospective cohort study of sepsis in critically ill surgical patients. BMJ Open 7:e015136. ...istent inflammation, immunosuppression and catabolism syndrome (PICS). The Sepsis and Critical Illness Research Center (SCIRC) was created to provide a platf
  3 KB (386 words) - 17:40, 27 November 2017
• Jang 2016 J Intensive Care Med
  ...2016) Measurement of mitochondrial respiration and motility in acute care: sepsis, trauma, and poisoning. J Intensive Care Med 32:86-94. ...l utility. Treatment of commonly encountered disease of acute care such as sepsis, trauma, and poisoning often relies on clinical diagnosis and therapy guide
  2 KB (252 words) - 23:26, 29 February 2020
• Lancel 2009 J Pharmacol Exp Ther
  ...B, Motterlini R, Neviere R (2009) Carbon monoxide rescues mice from lethal sepsis by supporting mitochondrial energetic metabolism and activating mitochondri ...) in biological systems have emerged as a potential adjunctive therapy for sepsis via their antioxidant, anti-inflammatory, and antiapoptotic effects. The ro
  3 KB (359 words) - 11:49, 22 December 2020
• Hara 2013 Eur J Anaesthesiol
  ...Uchino H (2013) Early brain mitochondrial dysfunction in a mouse model of sepsis: 7AP4‐9. Eur J Anaesthesiol 30,112-112. ...the temporal dynamics of brain mitochondrial function in a mouse model of sepsis.
  3 KB (428 words) - 13:45, 7 March 2020
• Weiss 2022 J Cell Mol Med
  ...gh which butyrate may help to mitigate the immuno-inflammatory response in sepsis. |keywords=Human immunology, Immunometabolism, Metabolism, Mitochondria, Sepsis
  2 KB (275 words) - 14:13, 28 November 2022
• Luther 2023 Am J Physiol Renal Physiol
  ...A, Frithiof R (2023) Renal mitochondrial dysfunction in ovine experimental sepsis associated acute kidney injury. https://doi.org/10.1152/ajprenal.00294.2022 ...of experiment and assessed ''in vitro'' with high resolution respirometry. Sepsis markedly reduced creatinine clearance and the relation between sodium trans
  3 KB (383 words) - 16:36, 2 May 2023
• Rutai 2019 Crit Care
  ...019) Potential role of endothelin receptors in the therapy of experimental sepsis. Crit Care. ...microcirculatory and mitochondrial respiration parameters in experimental sepsis.
  3 KB (365 words) - 14:50, 3 April 2019
• Karlsson 2016 Shock
  ...and tissue-specific mitochondrial respiratory response in a mouse model of sepsis-induced multiple organ failure. Shock 45:404-10. ...ggests a diverse and tissue-specific mitochondrial respiratory response to sepsis. The brain displayed an early impaired mitochondrial respiratory efficiency
  2 KB (351 words) - 13:40, 7 March 2020
• Preau 2014 Thesis University Lille
  ...yocardial dysfunction. Septic cardiomyopathy appears in the early phase of sepsis and is associated with fatal outcome. Complete recovery of myocardial funct sepsis that is suggested to postpone myocardium recovery. The first aim of the stu
  2 KB (291 words) - 09:51, 8 November 2016
• Wu 2023 Int Immunopharmacol
  |title=Wu F, Zhang YT, Teng F, Li HH, Guo SB (2023) S100a8/a9 contributes to sepsis-induced cardiomyopathy by activating ERK1/2-Drp1-mediated mitochondrial fis ...a9 may be a promising therapeutic strategy to prevent SIC in patients with sepsis.
  3 KB (372 words) - 17:08, 19 January 2023
• Sjoevall 2014 PLoS One
  ...Magnus J, Elmer E (2014) Cytokine and nitric oxide levels in patients with sepsis - temporal evolvement and relation to platelet mitochondrial respiratory fu ...d anti-inflammatory cytokines as well as NO plasma levels in patients with sepsis.
  3 KB (400 words) - 12:22, 16 September 2021
• MacMillan-Crow 2018 Intern Med Rev (Wash D C)
  ...ndrial injury but greater mortality using a comorbid model of experimental sepsis. Intern Med Rev (Wash D C) 4. ...in females. Our results suggest that the CLP nephrectomy comorbid model of sepsis may be an appropriate model to study gender differences a select group of p
  2 KB (354 words) - 11:35, 8 August 2019
• Halbach 2019 Am J Physiol Regul Integr Comp Physiol
  ...19) Early hyperbaric oxygen therapy improves survival in a model of severe sepsis. Am J Physiol Regul Integr Comp Physiol 317:R160-R168. ...after exposure to HBOT. Early HBOT could be of benefit in the treatment of sepsis and the protective mechanism may be related to a reduction in the systemic
  2 KB (378 words) - 12:25, 9 July 2019
• Sjoevall 2010 Crit Care
  ...espiration is negatively associated with clinical outcome in patients with sepsis. Crit Care 14:R214. ...al changes in platelet mitochondrial respiratory function in patients with sepsis during the first week after disease onset.
  3 KB (486 words) - 13:22, 27 December 2021
• Koenemann 2014 Dissertation
  ...en sollte [8]. Die Hyperglykämie kommt bei dem schweren Stress, der in der Sepsis auftritt, durch das Zusammenwirken von vermehrter Ausschüttung von katabol |diseases=Sepsis
  1 KB (150 words) - 14:56, 13 November 2017
• Markova 2017 MiP2017
  |title=[[Image:MarkovaM.jpg|left|90px|Michaela Markova]] Porcine sepsis and associated myocardial depression. ...n were addressed in a clinically relevant, large animal (porcine) model of sepsis and septic shock.
  4 KB (489 words) - 09:32, 13 October 2017
• Yan 2019 Int Immunopharmacol
  ...g J, Wang Y, Chen H, Xie K, Yu Y (2019) Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner. Int Immunopharmacol 71:6 ...gas inhalation for 3 h may serve as an effective therapeutic strategy for sepsis-induced liver injury through the regulation of FUNDC1-dependent mitophagy.
  3 KB (394 words) - 15:09, 21 March 2019
• Hara N
  |topics=Sepsis, mitochondrial dysfunction
  360 bytes (38 words) - 15:27, 13 February 2018
• Hwang 2021 Crit Care
  ...ases involving mitochondrial dysfunction, but it has never been tested for sepsis. ...the isolated mitochondria. We conducted both ''in vivo'' and ''in vitro'' sepsis studies. We investigated the effects of intravenous mitochondrial transplan
  3 KB (389 words) - 19:18, 12 January 2021
• Paumelle 2019 J Hepatol
  ..., Staels B (2019) Hepatic PPARα is critical in the metabolic adaptation to sepsis. J Hepatol 70:963-73. ...sm and inflammation. However, the role of hepatic PPARα in the response to sepsis is unknown.
  3 KB (520 words) - 11:47, 22 December 2020
• Correa 2012 Crit Care Med
  ...valuate how the delay in starting resuscitation influences the severity of sepsis and the treatment needed to achieve hemodynamic stability. ...tation on disease severity, need for resuscitation, and the development of sepsis-associated organ and mitochondrial dysfunction.
  3 KB (393 words) - 17:26, 9 November 2017
• Sjövall 2013 Thesis Lund University - Sweden
  |title=Sjövall F (2013) Mitochondrial function in sepsis - temporal evolvement of respiratory capacity in human blood cells. Thesis |diseases=Sepsis
  4 KB (603 words) - 16:07, 13 November 2017
• McCann 2020 Metabolites
  ...stimating platelet mitochondrial oxygen consumption rates in patients with sepsis. Metabolites 10:E139. ...directly estimate platelet mitochondrial oxygen consumption rate (mOCR) in sepsis patients.
  2 KB (293 words) - 12:36, 16 September 2021
• Herminghaus 2016 Abstract MitoFit Science Camp 2016
  ...patic but not colonic mitochondrial function similar to moderate abdominal sepsis. ...d colonic mitochondrial function after sterile laparotomy and by abdominal sepsis in the time course of 96 hours.
  3 KB (475 words) - 17:24, 7 November 2016
• Correa 2017 Crit Care
  ...d lactate levels, inflammation, and mitochondrial function in experimental sepsis. Crit Care 21:105. ..., inflammatory response, and mitochondrial respiration during experimental sepsis.
  3 KB (454 words) - 09:58, 12 June 2018
• Rutai 2019 Shock
  ...tential pargets for microcirculatory-mitochondrial therapy in experimental sepsis. Shock 54:87-95. ...microcirculatory and mitochondrial resuscitation strategy in experimental sepsis.
  3 KB (431 words) - 17:52, 30 June 2020
• Poles 2021 Front Immunol
  ...zaki J (2021) Kynurenic acid and its synthetic derivatives protect against sepsis-associated neutrophil activation and brain mitochondrial dysfunction in rat ...drial disturbances in a clinically relevant rodent model of intraabdominal sepsis.
  3 KB (486 words) - 09:54, 13 May 2023
• Tallosy 2021 Sci Rep
  ...omposition of the initial insult can predict the prognosis of experimental sepsis. Sci Rep 11:22772. ...loads with mono- or polymicrobial dominance lead to a different degree of sepsis severity and divergent outcomes. Initial and intraperitoneal microbiologica
  2 KB (301 words) - 14:49, 1 December 2021
• Volt 2016 J Pineal Res
  ...uña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res ...ths, chronoinflammaging constitutes the biochemical substrate of aging and sepsis, and identifies the NLRP3 inflammasome as a new molecular target for melato
  3 KB (361 words) - 08:04, 21 February 2020
• Garcia 2015 FASEB J
  ...rald a promising therapeutic application for melatonin in the treatment of sepsis. |diseases=Sepsis
  2 KB (321 words) - 00:50, 10 February 2020
• Rademann 2017 Oxid Med Cell Longev
  ...EMPO failed to exert a long-term beneficial effect in murine polymicrobial sepsis. Oxid Med Cell Longev 6412682. ...ssened inflammation and improved organ homeostasis in polymicrobial murine sepsis.
  3 KB (372 words) - 13:16, 26 June 2019
• Djafarzadeh 2011 Mitochondrion
  ...studies have shown the presence of liver mitochondrial dysfunction during sepsis. TLR3 recognizes viral double-stranded RNA and host endogenous cellular mRN hyperinflammatory response observed during sepsis and in sepsis RNA escaping from damaged tissues/cells may serve as an endogenous ligand f
  2 KB (248 words) - 04:26, 29 February 2020
• Doerrier 2014 Abstract SECF
  ...efore, we studied here whether Pfi are suitable to evaluate the effects of sepsis and melatonin treatment on mitochondrial function in Pfi. Mitochondrial function was analyzed during experimental sepsis induced by cecal ligation and punture (CLP) in hearts of 3 mo. C57BL/6 mice
  4 KB (598 words) - 17:47, 9 November 2017
• Doerrier 2012 Abstract Bioblast
  ...th melatonin prevents myocardial mitochondrial dysfunction in experimental sepsis in mice. Mitochondr Physiol Network 17.12. ...rreversibly impair all complex of the respiratory chain (RC). Thus, during sepsis, the activity of the respiratory complexes decreased significantly, favorin
  4 KB (548 words) - 11:15, 8 June 2020
• Garcia 2014 Abstract SECF
  |title=Melatonin disrupts the NF-κB/NLRP3 connection in sepsis through RORα receptor. ...n implicated in several acute and chronic inflammatory diseases, including sepsis and septic shock. Research efforts suggest that overstimulation of
  4 KB (552 words) - 16:58, 29 November 2016
• Puskarich Michael A
  |topics=Platelet, sepsis, post cardiac arrest
  474 bytes (61 words) - 18:55, 16 March 2020
• Correa 2014 Crit Care Med
  ...S: To compare effects of norepinephrine and angiotensin II in experimental sepsis on hemodynamics, organ function, and mitochondrial respiration. ...l muscle adenosine triphosphate. Modifying the renin-angiotensin system in sepsis should be further evaluated.
  3 KB (375 words) - 16:06, 7 November 2016
• Rontoyanni 2017 Shock
  ...etal muscle mitochondrial function is determined by burn severity, sex and sepsis, and is associated with glucose metabolism and functional capacity in burne ...and respiratory control (P < 0.05; n = 42, obs = 73), independent of age, sepsis, full-thickness burn size and time of clamp testing. Coupled respiration wa
  3 KB (468 words) - 15:15, 11 October 2018
• Puskarich 2016 J Crit Care
  ...o determine if changes in platelet mitochondrial function in patients with sepsis are present early after presentation and the association of these changes w ...observational cohort study of a convenience sample of patients with severe sepsis. Mitochondrial function of intact, nonpermeabilized platelets suspended in
  3 KB (353 words) - 12:17, 16 September 2021
• Protti 2006 Crit Care
  ...w: potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure. Crit Care 10:228. doi: 10.1186/cc5014 |abstract=The pathogenesis of sepsis-induced multiple organ failure may crucially depend on the development of m
  2 KB (200 words) - 01:08, 10 November 2023
• Wang 2017 Biochem Soc Trans
  ...et mitochondrial dysfunction in human diseases, such as diabetes mellitus, sepsis and neurodegenerative disorders. Alongside this, we have also articulated o |diseases=Diabetes, Neurodegenerative, Sepsis
  2 KB (211 words) - 12:36, 16 September 2021
• CA Sherbrooke Blondin DP
  ...word=Cold-induced thermogenesis, heat exposure, exercise, type 2 diabetes, sepsis, cardiomyopathy
  501 bytes (65 words) - 15:19, 31 October 2023
• Japiassu 2011 Crit Care Med
  ...nce points to the role of mitochondrial dysfunction in the pathogenesis of sepsis. Previous data indicate that mitochondrial function is affected in monocyte ...ic shock and a control group composed of 18 postoperative patients without sepsis or shock.
  4 KB (485 words) - 10:27, 15 April 2020
• Bloise 2020 Thyroid
  ...PL, Rocco PRM, Fliers E, Boelen A, da-Silva WS, Ortiga-Carvalho TM (2020) Sepsis impairs thyroid hormone signaling and mitochondrial function in the mouse d |abstract=Sepsis can cause the nonthyroidal illness syndrome (NTIS), resulting in perturbed
  3 KB (479 words) - 21:33, 20 August 2020
• Karlsson M
  :::: Research interests: Malaria, sepsis, multiple organ failure
  714 bytes (91 words) - 16:45, 11 February 2019
• Djafarzadeh 2012 PLoS One
  ...ygen consumption with energy production has been described. In addition to sepsis, pharmacological agents used to treat septic patients may contribute to mit |keywords=Sepsis, Liver dysfunction, Remifentanil, Tumor necrosis factor-α (TNF-α), Caspas
  3 KB (376 words) - 17:47, 9 November 2017
• Maher 2014 J Biol Chem
  ...xide generation. Collectively, our study demonstrates that the LPS-induced sepsis in StB KO mice is dependent on caspase-11 and mitochondrial reactive oxygen |keywords=Caspase, Inflammasome, Mitochondria, Reactive Oxygen Species (ROS), Sepsis
  2 KB (292 words) - 15:32, 27 July 2016
• Merz 2018 Intensive Care Med Exp
  ...ine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis. Intensive Care M |abstract=Sepsis is associated with disturbed glucose metabolism and reduced mitochondrial a
  3 KB (443 words) - 15:37, 30 October 2018
• Herminghaus 2014 Abstract MiP2014
  |title=Severity of polymicrobial sepsis modulates mitochondrial function in rat liver. ...t study was to analyze hepatic mitochondrial function during polymicrobial sepsis with abdominal focus, depending on severity of the septic process.
  4 KB (574 words) - 17:24, 7 November 2016
• Wefers 2019 J Emergency Critical Care Med
  ...complex pathophysiology of a critically ill patient, especially in severe sepsis and septic shock, requires a multilevel approach. In understanding the inte |diseases=Sepsis
  3 KB (457 words) - 11:30, 16 March 2024
• Hecker 2014 JPEN
  |abstract='''Background:''' Sepsis is a severe inflammatory disorder with a high mortality in intensive care u ...lls were pretreated with tumor necrosis factor-α to mimic inflammation and sepsis. Results: We demonstrated that addition of SCFAs and MCFAs increases mitoch
  2 KB (330 words) - 14:33, 13 November 2017
• Thomas 2011 Mitochondrion
  ...dependently improved survival in the lipopolysaccharide model of endotoxin sepsis. |keywords=Recombinant TFAM, Mitochondrial biogenesis, ATP synthesis, MPTP, Sepsis
  2 KB (214 words) - 15:36, 9 November 2016
• Quoilin 2014 Dissertation
  ...n C (2014) Les effets délétères métaboliques et oxydants induits lors d'un sepsis sur la fonction rénale. Dissertation 1-195. |abstract=Acute kidney injury (AKI) is a frequent complication of sepsis that can increase mortality as high as 70%. The pathophysiology of this kid
  4 KB (581 words) - 12:21, 14 December 2015
• Li 2022 Mol Med
  ...avy burden for national health system around the world. It is notable that sepsis is the predominant cause of AKI for patients in the intensive care unit and We employed mice sepsis-induced AKI model and explored the potential renoprotective effect of sperm
  3 KB (361 words) - 13:33, 26 September 2022
• Makrecka-Kuka 2017 MiP2017
  ...ial function are associated with the development of multi-organ failure in sepsis. The aim of the present study was to evaluate the dynamics of heart, brain In conclusion, the obtained results demonstrate that sepsis-induced mitochondrial damage is tissue specific and time-dependent. The kid
  3 KB (453 words) - 12:17, 3 October 2017
• Correa 2013 Crit Care
  ...deh S, Silva E, Jakob SM (2013) Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function. Crit Care 1 ...w.ncbi.nlm.nih.gov/pubmed/?term=Increasing+mean+arterial+blood+pressure+in+sepsis%3A+effects+on+fluid+balance%2C+vasopressor+load+and+renal+function PMID: 23
  3 KB (427 words) - 16:06, 7 November 2016
• Patil 2015 Abstract MiPschool Greenville 2015
  ...ract=Burn patients are at increased risk of developing wound infection and sepsis leading to multi-organ failure and death [1]. Previous studies show that T ...herapeutic benefit in prevention and/or treatment of burn wound associated sepsis.
  4 KB (555 words) - 10:24, 21 July 2015
• Jang 2017 Mitochondrion
  ...rt of healthy subjects as well as a cohort of hospitalized subjects having sepsis, an acute care illness. As there is increasing use of human blood cells as |keywords=Mitochondria, Motility, Sepsis, Microscopy
  2 KB (279 words) - 23:24, 29 February 2020
• Drechsler 2015 Intensive Care Medicine Experimental
  ...rgan injury and dysfunction in mice surviving and dying in acute abdominal sepsis. Intensive Care Medicine Experimental 3:12. |abstract=The mechanisms of sepsis mortality remain undefined. While there is
  3 KB (478 words) - 17:50, 9 November 2017
• Hassoun 2008 Crit Care Med
  ...culum Ca²⁺ handling derangements that are typically observed in sepsis. As lipopolysaccharide-induced sarcoplasmic reticulum dysfunction was mainl '''INTERVENTIONS''': Sepsis was induced by injection of endotoxin lipopolysaccharide (10 mg/kg/intraven
  3 KB (426 words) - 11:50, 22 December 2020
• Hecker 2018 Biochim Biophys Acta
  |abstract=Inflammatory disorders such as sepsis are a major cause of morbidity and mortality. Mitochondrial dysfunction is |diseases=Sepsis
  2 KB (265 words) - 14:37, 5 July 2023
• Merz 2017 Intensive Care Med Exp
  ...r group) underwent cecal ligation and puncture (CLP)-induced polymicrobial sepsis or sham procedure (n = 6 per group) and, 15 h afterwards, were anesthet In sepsis combined with hyperglycemia the least CSE and PGC1α expression could be de
  3 KB (366 words) - 15:18, 13 November 2017
• Jeger 2015 BioMed Res Internat
  |abstract=Results on mitochondrial dysfunction in sepsis are controversial. We aimed to assess effects of LPS at wide dose and time |diseases=Sepsis
  2 KB (291 words) - 14:46, 13 November 2017
• Acuna-Castroviejo Dario
  ::::: '''Keywords:''' melatonin, mitochondria, aging, sepsis, cancer, neurodegeneration/neuroprotection
  1 KB (123 words) - 10:53, 19 November 2021
• Juhasz 2017 MiPschool Obergurgl
  ...t|90px]] Blockade of N-methyl-D-aspartate receptors improves polymicrobial sepsis-evoked mitochondrial dysfunction in rats. ...affects mitochondrial respiration in a rodent model of peritonitis-induced sepsis (PS).
  4 KB (555 words) - 13:33, 28 March 2018
• Regueira 2008 Crit Care Med
  ...unction of using norepinephrine to increase blood pressure in experimental sepsis. |keywords=Sepsis
  4 KB (450 words) - 17:15, 27 March 2018
• Trumbeckaite 2001 Eur J Biochem
  sepsis on the function of heart and skeletal |keywords=Sepsis, Endotoxin, Mitochondria, Heart, Skeletal muscle, LPS
  3 KB (366 words) - 10:54, 23 January 2019
• Mayevsky 2007 Mitochondrion
  ...drial dysfunction is part of many pathological states in patients, such as sepsis or stroke. Presently, the monitoring of mitochondrial function in patients
  1 KB (168 words) - 10:58, 4 February 2022
• Jiroutkova 2014 Intensive Care Medicine Experimental
  ...) is known to contribute to the development of multiorganmfailure in acute sepsis. The defect is mainly at the level of respiratory complex I [1,2]. |diseases=Sepsis
  3 KB (402 words) - 12:09, 9 December 2021
• Wang 2018 Cell Physiol Biochem
  |abstract=The pathogenesis of sepsis-associated encephalopathy (SAE) is multifactorial, involving neurotransmitt |keywords=Apoptosis, CLP, Omi/HtrA2, Sepsis-associated encephalopathy, UCF-101
  4 KB (578 words) - 00:35, 1 March 2020
• Laupland 2009 Crit Care Med
  |diseases=Sepsis
  1 KB (183 words) - 12:00, 16 June 2015
• PBMC
  ...active protein, interleukin-6 and white blood cell count for prediction of sepsis and nonsystemic bacterial infections. Int J Lab Hematol 32:410-8]
  1 KB (152 words) - 15:16, 21 February 2024
• Kozlov 2010 Inflammation
  |diseases=Sepsis * [[O2k-Publications: Sepsis]]
  3 KB (420 words) - 04:01, 23 November 2021
• CH Bern Djafarzadeh S
  INTRODUCTION. Mitochondrial dysfunction has been implicated in sepsis-induced organ failure. ...sumption were maintained without signs of deteriorated efficiency. In this sepsis model, organ failure and death were not associated with impaired skeletal m
  3 KB (404 words) - 10:00, 20 February 2020
• Mars T
  ...rgy metabolism and skeletal muscle in special condition-ischemia, hypoxia, sepsis) we found several topics in the COST Action particularly interesting. Indee
  1 KB (178 words) - 17:39, 30 October 2019
• Jeger 2013 Abstracts of ESICM LIVES 2013
  |abstract=Hepatic mitochondrial function may be impaired in sepsis, and it has |keywords=Sepsis, Mitochondria, Cytokines, Mitochondrial Respiration, Caspase- 3, Actin, We
  3 KB (431 words) - 16:29, 27 March 2018
• Makrecka-Kuka 2018 MiP2018
  ...Makrecka-Kuka]] Fatty acid oxidation in brain: from aging to ischemia and sepsis. |diseases=Aging;senescence, Neurodegenerative, Sepsis
  3 KB (473 words) - 12:11, 3 November 2018
• Hecker 2015 Methods Mol Biol
  |diseases=Sepsis
  1 KB (197 words) - 14:34, 13 November 2017
• Garcia-Souza 2014 Int J Biochem Cell Biol
  |diseases=Alzheimer's, Diabetes, Parkinson's, Sepsis
  1 KB (202 words) - 17:10, 27 March 2018
• Bullon 2015 Pharmacol Res
  ...ative stress in several pathological events such as periodontal disease or sepsis. In our experiments, LPS-treated fibroblasts provoked increased oxidative s
  2 KB (208 words) - 15:27, 9 November 2016
• Vanasco 2008 Free Radic Res
  ...se was observed in in situ skeletal muscle chemiluminescence. Experimental sepsis increased oxygen consumption in tissue cubes (1 mm(3)) by 30 % for heart an
  1 KB (213 words) - 11:38, 18 April 2021
• Dungel 2008 Arch Biochem Biophys
  ...the efficiency of GTN was lower compared to NO concentrations observed in sepsis models. However, GTN inhibition was absolutely insensitive to illumination
  2 KB (244 words) - 15:44, 20 March 2015
• Reiter 2003 Acta Biochim Pol
  ...nzymes, Free radicals, Melatonin, Neurodegeneration, Respiratory distress, Sepsis
  2 KB (252 words) - 00:54, 10 February 2020
• Nauta 2016 Thesis
  related to pathological conditions, including sepsis (21), acute lung injury (47), and cancer
  2 KB (305 words) - 10:53, 29 November 2017
• Mayer 2019 Lipids
  |abstract=Severe inflammatory disorders such as sepsis are a major cause of morbidity and mortality worldwide. Mitochondrial dysfu
  2 KB (252 words) - 10:18, 25 July 2019
• Gutierrez-Sacristan 2018 Bioinformatics
  ...scular, COPD, Diabetes, Myopathy, Neurodegenerative, Obesity, Parkinson's, Sepsis, Other
  2 KB (298 words) - 00:35, 16 February 2020
• Kopitar-Jerala 2015 Front Cell Neurosci
  ...ignificantly more sensitive to the lethal lipopolysaccharide (LPS)-induced sepsis, due to increased caspase-11 expression and secreted higher amounts of pro-
  2 KB (286 words) - 13:40, 27 July 2016
• Acuna-Castroviejo 2012 Abstract Bioblast
  ...dysfunction, different experimental models of aging and disease, including sepsis, Parkinson’s disease, and Alzheimer’s disease, was evaluated. In all of ...ses=Aging;senescence, Alzheimer's, Cancer, Neurodegenerative, Parkinson's, Sepsis
  5 KB (658 words) - 15:44, 7 November 2016
• Tian 2021 Front Physiol
  ...ty of acute and chronic inflammatory diseases, such as acute pancreatitis, sepsis, respiratory disease, ischemia reperfusion injury diseases, autoimmunity di
  2 KB (324 words) - 14:59, 24 December 2021
• Doerrier Carolina
  ...-FluoRespirometry, oxidative stress, permeabilized muscle fibers, NAD(P)H, sepsis, aging, melatonin ...Melatonin]], [[Reactive oxygen species]], [[Reactive nitrogen species]], [[Sepsis]]
  6 KB (675 words) - 14:21, 20 October 2022
• Kozlov 2010 Abstract IOC60
  |diseases=Sepsis, Other
  2 KB (349 words) - 14:03, 16 June 2015
• MitoEAGLE data: blood and cultured cells
  ...d cells was linked with numerous diseases and metabolic conditions such as sepsis, neurodegenerative diseases, depression, hypertension, amyotrophic lateral
  3 KB (390 words) - 16:47, 12 January 2018
• Hansen 2015 Shock
  ...in tissues and blood. Elevated circulating LPS is a feature of obesity and sepsis, both of which are associated with mitochondrial abnormalities that are key
  3 KB (365 words) - 14:31, 13 November 2017
• Leduc-Gaudet 2023 Nat Commun
  ...enuates muscle atrophy caused by fasting, denervation, cancer cachexia and sepsis. While MYTHO overexpression is sufficient to trigger muscle atrophy, MYTHO
  3 KB (370 words) - 13:35, 14 March 2023
• Cheng 2014 Science
  ...c defect in HIF-1α were unable to mount trained immunity against bacterial sepsis. Our results indicate that induction of aerobic glycolysis through an Akt-m
  2 KB (345 words) - 23:12, 29 February 2020
• Ferguson 2016 J Bioenerg Biomembr
  |abstract=Cardiac arrest (CA) results in a sepsis-like syndrome with activation of the innate immune system and increased mit
  3 KB (391 words) - 12:17, 16 September 2021
• Clere-Jehl 2018 Shock
  |diseases=Sepsis
  3 KB (405 words) - 14:36, 5 July 2023
• Chakraborty 2013 Abstracts of ESICM LIVES 2013
  organ failure but whether it is causal is not known because temporal MR in sepsis or MODS
  3 KB (469 words) - 11:54, 20 October 2017
• Widmann 2014 Thesis
  |diseases=Sepsis
  3 KB (435 words) - 16:32, 13 November 2017
• Calzia 2013 Abstract MiP2013
  |diseases=Sepsis ...r 5 h of mechanical ventilation. Treatments were control (closed bars) vs. sepsis (CLP-induced, light bars), intravenous Na2S (diagrams B and D) vs. placebo
  6 KB (896 words) - 17:09, 9 November 2017
• Oroboros 2007
  ...rument exhibition at 7th World Congress on TRAUMA, SHOCK, INFLAMMATION AND SEPSIS - TSIS2007, Munich, Germany, 13-17 March 2007: http://www.tsis2007.org/indu | Munich, DE: 7th World Congress on TRAUMA, SHOCK, INFLAMMATION AND SEPSIS - TSIS2007 - Interdisciplinary Summit on Inflammation. [http://www.TSIS2007
  9 KB (1,112 words) - 14:44, 25 January 2020
• Kozlov 2013 Abstract MiP2013
  |diseases=Sepsis
  3 KB (471 words) - 11:17, 28 April 2017
• Nedel 2021 Intensive Care Med Exp
  |diseases=Sepsis
  3 KB (452 words) - 14:29, 2 August 2021
• Tapia 2015 Crit Care
  |diseases=Sepsis
  3 KB (465 words) - 10:26, 8 November 2016
• Kopitar-Jerala 2018 MiP2018
  ...ignificantly more sensitive to the lethal lipopolysaccharide (LPS)-induced sepsis due to increased caspase-11 expression [3]. Upon LPS stimulation, stefin B
  3 KB (480 words) - 09:35, 20 August 2018
• O2k-Publications: Topics
  | style="text-align:left"|[[O2k-Publications: Sepsis|Sepsis]] ...Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Diseases::Sepsis]] |format=count}}
  62 KB (7,038 words) - 14:31, 22 August 2023
• MiPMap
  ...• Infectious •• Myopathy •• Neurodegenerative •• Obesity •• Parkinson's •• Sepsis •• Other
  7 KB (696 words) - 11:14, 20 October 2017
• WISe3 2018 Szeged HU
  :::::* Mitochondrial function in sepsis, haemorrhagic shock and ischemia-reperfusion injury
  7 KB (937 words) - 11:27, 8 August 2019
• MiPschool 2012 Cambridge UK Programme
  |Cancer, Sepsis & Immunity session |Mervyn Singer - Mitochondria and sepsis
  14 KB (1,865 words) - 16:38, 30 June 2017
• MiPNet12.16 1st MitoPathways Workshop
  ...uitability of using BSA when detecting mitochondrial dysfunction following sepsis/ischemia/Huntingtons disease/neurotoxicology;
  7 KB (1,008 words) - 10:21, 23 January 2019
• MiPNet19.06 IOC91 Philadelphia US
  ..., US_PA Philadelphia_Becker LB: The Children's Hospital of Philadelphia. - Sepsis, pediatrics, peripheral blood mononuclear cells.
  10 KB (1,436 words) - 02:21, 9 October 2019
• MiPschool 2007 Schroecken AT Programme
  |'''Enrico Calzia'''(Ulm, DE) Small and large animal models of sepsis and I/R-injury - how to combine basic science and clinical reality.
  12 KB (1,502 words) - 15:07, 22 March 2017
• MitoFit SC 2016 Programme information
  ...d cells was linked with numerous diseases and metabolic conditions such as sepsis, neurodegenerative diseases, depression, hypertension, amyotrophic lateral ...patic but not colonic mitochondrial function similar to moderate abdominal sepsis.
  34 KB (4,472 words) - 11:55, 12 March 2024
• Melatonin
  During inflammatory diseases (such as sepsis or fibromyalgia), an induction occurs in mitochondria of i-mtNOS (inducible
  15 KB (2,166 words) - 14:12, 24 September 2023
• Brown 2020 MitoFit Preprint Arch
  ...reating the host response to emerging virus diseases: lessons learned from sepsis, pneumonia, influenza and Ebola Vol 4, No 21 (November 2016) http://atm.ame
  27 KB (3,615 words) - 08:19, 8 January 2023
• MitoFit Science Camp 2016 Kuehtai AT
  ...patic but not colonic mitochondrial function similar to moderate abdominal sepsis.]]
  27 KB (3,721 words) - 13:27, 3 April 2022
• Short-Term Scientific Missions MitoEAGLE
  ...es of GPx, GRd and MnSOD, ...); mouse models of diseases including aging, sepsis, Parkinson's disease, mitochondrial diseases. Primary cell models of mitoch
  41 KB (5,420 words) - 15:06, 23 November 2020
• Gnaiger 2024 J Biol Chem
  ...SS (2022) Regulation of oxidative phosphorylation of liver mitochondria in sepsis. '''Cells''' 11:1598. - [[Eyenga 2022 Cells |»Bioblast link«]]
  135 KB (18,142 words) - 13:29, 1 May 2024
• Oroboros Ecosystem Agenda 2021 Archive
  ...ation improves survival and bacterial clearance in a cecal slurry model of sepsis''' <br>
  85 KB (11,819 words) - 14:18, 10 January 2022