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| {{Mainpage mitopedia}}
| | #REDIRECT [[MitoEAGLE]] |
| [[Image:MitoGlobal.jpg|left|160px|link=http://www.bioblast.at/index.php/Mitochondrial_Global_Network|MitoGlobal]]
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| <br />
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| <big><big>'''EAGLE data base on mitochondrial physiology'''</big></big>
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| <big><big>'''E'''</big>volution - <big>'''A'''</big>ge - <big>'''G'''</big>ender - <big>'''L'''</big>ifestyle - <big>'''E'''</big>nvironment</big>
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| __TOC__
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| == Summary ==
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| Every study of mitochondrial (mt) function and disease in human tissues is faced with EAGLE as the essential background conditions characterizing the individual patient, subject or study group. A general data base on mitochondrial function is required to set results into the multidimensional context of EAGLE. The EAGLE database on mitochondrial physiology and pathology may be compared to established genomic and proteomic data bases on human evolution and mitochondrial medicine on one hand, and physiological data bases of sport science on the other hand. An EAGLE data base does not exist, is necessary to interrelate results of different studies, to interpret pathological states, and must be operated on a global scale. The following steps should be taken towards establishing the EAGLE database.
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| == First steps ==
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| # Initiate a consortium of research groups involved in studies of mitochondrial function in human tissues, with a focus on (i) muscle biopsies, (ii) blood cells, and (iii) fat tissue. These groups include specialists on sports science, nutrition and life style, ageing and human diseases.
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| # Organize a series of start-up meetings of members of the consortium with a minimum of added costs, by integrating EAGLE sessions in regular meetings of established [[MitoGlobal_Organizations |mitochondrial societies]]. Satellite workshops might extend the activities of the consortium, which may lead to continuing inter-laboratory studies, development of standards for quality control and teaching initiatives to disseminate and certify such standards for quality control.
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| # Contact organizations operating comparable genomic and physiological databases, to share their expertise.
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| # Contact funding bodies towards funding the initiation and operation of the mtEAGLE database.
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| == EAGLE consortium ==
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| * EAGLE was discussed at various meetings in 2014, including the [[ISMM2014 |World Congress on High Altitude Medicine and Physiology in Bolzano, Italy]], the [[MiPNet19.06 IOC91 |O2k-Workshop in Philadelphia]], the [[UMDF2014 |UMDF meeting in Pitzburgh, US]]; [[EUROMIT2014 |EUROMIT in Tampere, Finland]], [[EBEC2014 |EBEC in Lisbon, Portugal]], [[MiP2014 |MiP in Obergurgl, Austria]], and [[ASMRM 2014 |ASMRM in Taipei, Taiwan]]. Your input, evaluation and suggestions are most welcome. The following list, summarizing contacted colleagues and involved research groups, may expand rapidly. The [[Mitochondrial_Global_Network |MitoGlobal framework]] offers an Open Access/Open Innovation approach. - 2014-11-18 [[Gnaiger Erich]]
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| * Contact: [[Gnaiger E |Erich Gnaiger]]
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| {{#ask:[[MitoPedia topic::EAGLE]] [[In country::+]]
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| | mainlabel=-
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| |?In country=Country
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| |?In city=City
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| |?=Institution
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| |?Has contact=Contact
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| |sort=In country
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| |order=ascending
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| |limit=5000
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| |format=broadtable
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| |offset=0
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| }}
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| == Links ==
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| * National Exercise Clinical Trials Network (contact [[Lai Nicola]])
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| :: http://www.uab.edu/medicine/exercise/nextnet
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| :: To share exercise data among the different national labs we are using redcap: http://www.project-redcap.org/
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| * NINDS Mitochondrial Diseases Common Data Element Project - Public Review Period: November 20, 2014 - January 16, 2015
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| :: http://www.commondataelements.ninds.nih.gov/MITO.aspx#tab=Data_Standards
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| * The concept of a previous COST application (MitoScore) might be partially integrated into the EAGLE concept
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| :: http://www.bioblast.at/index.php/MitoScore
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| [[Category:Mitochondrial Global Network]] | |
