Difference between revisions of "Carnitine palmitoyltransferase II"

Latest revision as of 16:45, 13 April 2023

high-resolution terminology - matching measurements at high-resolution

Carnitine palmitoyltransferase II

Description

Carnitine palmitoyltransferase II (CPT-II, also known as carnitine acyltransferase II) is part of the carnitine shuttle which is responsible for the mitochondrial transport of long-chain fatty acids. CPT-II is located on the inner side of the mtIM and converts the acylcarnitines (produced in the reaction catalyzed by carnitine palmitoyltransferase I) to carnitine and acyl-CoAs, which undergo ß-oxidation in the mitochondrial matrix. Free carnitines are transported out of the mitochondrial matrix in exchange for acyl-carnitines via an integral mtIM protein carnitine-acylcarnitine translocase (CACT). Short- and medium-chain fatty acids do not require the carnitine shuttle for mitochondrial transport.

Abbreviation: CPT-II

MitoPedia topics: Enzyme

Labels:

MitoPedia:FAT4BRAIN

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 {{MitoPedia
-|abbr=CPT-2
+|abbr=CPT-II
-|description='''Carnitine palmitoyltransferase 2''' (CPT-2, also known as carnitine acyltransferase II) is part of the carnitine shuttle which is responsible for the mitochondrial transport of long-chain fatty acids for mitochondrial [[fatty acid oxidation]]. CPT-2 is located on the inner side of the mtIM and converts the acyl-carnitines to carnitine and acyl-CoAs, which undergo ß-oxidation in the mitochondrial matrix. Free carnitines are transported out of the mitochondrial matrix in exchange for acyl-carnitines via an integral mtIM protein [[carnitine-acylcarnitine translocase]] (CACT). Short- and medium-chain fatty acids do not require the carnitine shuttle for mitochondrial transport.
+|description='''Carnitine palmitoyltransferase II''' (CPT-II, also known as carnitine acyltransferase II) is part of the carnitine shuttle which is responsible for the mitochondrial transport of long-chain fatty acids. CPT-II is located on the inner side of the mtIM and converts the [[acylcarnitine]]s (produced in the reaction catalyzed by [[carnitine palmitoyltransferase I]]) to carnitine and acyl-CoAs, which undergo ß-oxidation in the mitochondrial matrix. Free carnitines are transported out of the mitochondrial matrix in exchange for acyl-carnitines via an integral mtIM protein [[carnitine-acylcarnitine translocase]] (CACT). Short- and medium-chain fatty acids do not require the carnitine shuttle for mitochondrial transport.
-|type=
-}}
-{{MitoPedia methods|type=
 }}
 {{MitoPedia topics
 |mitopedia topic=Enzyme
-|type=
+}}
+{{Labeling
+|additional=MitoPedia:FAT4BRAIN
 }}