Difference between revisions of "Carnitine palmitoyltransferase II"
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|description='''Carnitine palmitoyltransferase | |description='''Carnitine palmitoyltransferase II''' (CPT-II, also known as carnitine acyltransferase II) is part of the carnitine shuttle which is responsible for the mitochondrial transport of long-chain fatty acids. CPT-II is located on the inner side of the mtIM and converts the [[acylcarnitine]]s (produced in the reaction catalyzed by [[carnitine palmitoyltransferase I]]) to carnitine and acyl-CoAs, which undergo ß-oxidation in the mitochondrial matrix. Free carnitines are transported out of the mitochondrial matrix in exchange for acyl-carnitines via an integral mtIM protein [[carnitine-acylcarnitine translocase]] (CACT). Short- and medium-chain fatty acids do not require the carnitine shuttle for mitochondrial transport. | ||
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{{MitoPedia topics | {{MitoPedia topics | ||
|mitopedia topic=Enzyme | |mitopedia topic=Enzyme | ||
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Latest revision as of 16:45, 13 April 2023
- high-resolution terminology - matching measurements at high-resolution
Carnitine palmitoyltransferase II
Description
Carnitine palmitoyltransferase II (CPT-II, also known as carnitine acyltransferase II) is part of the carnitine shuttle which is responsible for the mitochondrial transport of long-chain fatty acids. CPT-II is located on the inner side of the mtIM and converts the acylcarnitines (produced in the reaction catalyzed by carnitine palmitoyltransferase I) to carnitine and acyl-CoAs, which undergo ß-oxidation in the mitochondrial matrix. Free carnitines are transported out of the mitochondrial matrix in exchange for acyl-carnitines via an integral mtIM protein carnitine-acylcarnitine translocase (CACT). Short- and medium-chain fatty acids do not require the carnitine shuttle for mitochondrial transport.
Abbreviation: CPT-II
MitoPedia topics:
Enzyme
Labels:
MitoPedia:FAT4BRAIN
