Difference between revisions of "Carnitine palmitoyltransferase II"
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|abbr=CPT-2 | |abbr=CPT-2 | ||
|description='''Carnitine palmitoyltransferase 2''' (CPT-2, also known as carnitine acyltransferase II) is part of the carnitine shuttle which is responsible for the mitochondrial transport of long-chain fatty acids | |description='''Carnitine palmitoyltransferase 2''' (CPT-2, also known as carnitine acyltransferase II) is part of the carnitine shuttle which is responsible for the mitochondrial transport of long-chain fatty acids. CPT-2 is located on the inner side of the mtIM and converts the acyl-carnitines (produced in the reaction catalyzed by [[carnitine palmitoyltransferase I]]) to carnitine and acyl-CoAs, which undergo ''ß''-oxidation in the mitochondrial matrix. Free carnitines are transported out of the mitochondrial matrix in exchange for acyl-carnitines via an integral mtIM protein [[carnitine-acylcarnitine translocase]] (CACT). Short- and medium-chain fatty acids do not require the carnitine shuttle for mitochondrial transport. | ||
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Revision as of 10:23, 19 November 2020
- high-resolution terminology - matching measurements at high-resolution
Carnitine palmitoyltransferase II
Description
Carnitine palmitoyltransferase 2 (CPT-2, also known as carnitine acyltransferase II) is part of the carnitine shuttle which is responsible for the mitochondrial transport of long-chain fatty acids. CPT-2 is located on the inner side of the mtIM and converts the acyl-carnitines (produced in the reaction catalyzed by carnitine palmitoyltransferase I) to carnitine and acyl-CoAs, which undergo ß-oxidation in the mitochondrial matrix. Free carnitines are transported out of the mitochondrial matrix in exchange for acyl-carnitines via an integral mtIM protein carnitine-acylcarnitine translocase (CACT). Short- and medium-chain fatty acids do not require the carnitine shuttle for mitochondrial transport.
Abbreviation: CPT-2
MitoPedia topics: Enzyme
