Template:Current week ecosystem agenda

Oroboros declares solidarity against the Russian aggression-war in Ukraine and against all aggression-wars worldwide. - »More details

-» A future for Ukraine is the future of its science

2023 Week 51

Dec- 18 Mo

»SBC 2023 Goa IN« Dec 18-20

Why add azide after ascorbate and TMPD when measuring Complex IV activity?

The O₂ flux measured after the titration of ascorbate and TMPD is due to both CIV activity and autooxidation of these compounds. By subsequently inhibiting CIV activity with azide, the O₂ flux due to autooxidation (chemical background) can be determined and subtracted from the initial measurement.
- »Complex IV«, »Chemical background «
- communicated by »Grings Mateus« and »Timon-Gomez Alba«

Dec- 19 Tu

Dec- 20 We

"SIRT4 [Sirtuin 4] knockdown increases mitochondrial capacity to oxidize fatty acids, decreasing LEAK respiration and further increasing mitochondrial elongation via its regulation of mitochondrial fusion."

Noone J, Rochfort KD, O'Sullivan F, O'Gorman DJ (2023) SIRT4 is a regulator of human skeletal muscle fatty acid metabolism influencing inner and outer mitochondrial membrane-mediated fusion. »Bioblast link«

from the O2k-Network »US FL Orlando Goodpaster BH« and »IE Dublin O Gorman D«

Dec- 21 Th

Dec- 22 Fr

Next Week

2023 Week 52

Dec- 25 Mo

Dec- 26 Tu

Dec- 27 We

Do you observe a high signal at zero oxygen?

If the quality of your dithionite solution has already been checked, perform a leak current test to evaluate which electrical component is generating the out-of-scale signal.
- »Leak current test«
- communicated by »Baglivo Eleonora« and »Grings Mateus«

Dec- 28 Th

Dec- 29 Fr

"Leptin receptor signaling in Schwann cells adjusts catabolic processes, including mitochondrial respiration and autophagy, facilitating nerve repair."

Sundaram VK, Schütza V, Schröter NH, Backhaus A, Bilsing A, Joneck L, Seelbach A, Mutschler C, Gomez-Sanchez JA, Schäffner E, Sánchez EE, Akkermann D, Paul C, Schwagarus N, Müller S, Odle A, Childs G, Ewers D, Kungl T, Sitte M, Salinas G, Sereda MW, Nave KA, Schwab MH, Ost M, Arthur-Farraj P, Stassart RM, Fledrich R (2023) Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration. »Bioblast link«

from the O2k-Network »DE_Leipzip_Ost_M«