Difference between revisions of "Template:Current week ecosystem agenda"

Revision as of 09:57, 11 December 2023

Oroboros declares solidarity against the Russian aggression-war in Ukraine and against all aggression-wars worldwide. - »More details

-» A future for Ukraine is the future of its science

2023 Week 50

Dec- 11 Mo - International Mountain Day

Mountain slopes can be difficult, but O₂ slopes can be smooth with DatLab

The default setting of Slope smoothing is 40 data points, corresponding to an interval of 80 s at a data recording interval of 2 s. DatLab 7 expresses it in data points and DatLab 8 in seconds.
- »Smoothing in Flux/Slope«
- communicated by »Timon-Gomez Alba« and »Baglivo Eleonora«

Dec- 12 Tu

From preprint to Gold Open Access publication in J Biol Chem

Gnaiger E (2023) Complex II ambiguities ― FADH2 in the electron transfer system. »Bioblast link«

Dec- 13 We

Dec- 14 Th

"HCR [High capacity runner rats] showed a consistent and robust trend of higher maximal oxygen consumption compared to LCR [low capacity runner rats], especially for long chain FAs [fatty acids]."

Fleischman JY, Van den Bergh F, Collins NL, Bowers M, Beard DA, Burant CF (2023) Higher mitochondrial oxidative capacity is the primary molecular differentiator in muscle of rats with high and low intrinsic cardiorespiratory fitness. »Bioblast link«

from the O2k-Network »US MI Ann Arbor Beard DA«

Dec- 15 Fr

Next Week

2023 Week 51

Dec- 18 Mo

»SBC 2023 Goa IN« Dec 18-20

Why add azide after ascorbate and TMPD when measuring Complex IV activity?

The O₂ flux measured after the titration of ascorbate and TMPD is due to both CIV activity and autooxidation of these compounds. By subsequently inhibiting CIV activity with azide, the O₂ flux due to autooxidation (chemical background) can be determined and subtracted from the initial measurement.
- »Complex IV«, »Chemical background «
- communicated by »Grings Mateus« and »Timon-Gomez Alba«

Dec- 19 Tu

Dec- 20 We

"SIRT4 [Sirtuin 4] knockdown increases mitochondrial capacity to oxidize fatty acids, decreasing LEAK respiration and further increasing mitochondrial elongation via its regulation of mitochondrial fusion."

Noone J, Rochfort KD, O'Sullivan F, O'Gorman DJ (2023) SIRT4 is a regulator of human skeletal muscle fatty acid metabolism influencing inner and outer mitochondrial membrane-mediated fusion. »Bioblast link«

from the O2k-Network »US FL Orlando Goodpaster BH« and »IE Dublin O Gorman D«

Dec- 21 Th

Dec- 22 Fr

@@ Line 1: / Line 1: @@
 {{Template:Science for Ukraine}}
-Week 49
-*'''Dec- 04 Mo'''
-----
-*'''Dec- 05 Tu'''
-:{|
-| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
-|''' Is DatLab 8 compatible with your operative system?'''<br>
-The DatLab 8 software is designed for 64-bit versions of Windows operating systems and does not run on MAC devices.
-<br>
-- »'''[https://www.oroboros.at/index.php/product/datlab/ DatLab 8]'''«<br>
-- communicated by »[[Leo Elettra]]« and »[[Baglivo Eleonora]]«
-|}
-----
-*'''Dec- 06 We'''
-:{|
-| width="100" align="center" |[[File:MitoFit Preprints.png|100px|link=https://wiki.oroboros.at/images/0/00/Cecatto_2023_MitoFit.pdf |MitoFit pdf]]
-|'''"The capacity of FA oxidative phosphorylation (F-OXPHOS) with palmitoylcarnitine was up to 4 times higher than respiration with octanoylcarnitine. The optimal concentration of palmitoylcarnitine was 10 μM which corresponds to the total concentration of LC acylcarnitines in the brain."'''<br>
-* Cecatto C, Cardoso LHD, Ozola M, Korzh S, Zvejniece L, Gukalova B, Doerrier C, Dambrova M, Gnaiger E, Makrecka-Kuka M, Liepinsh E (2023) Fatty acid β-oxidation in brain mitochondria: Insights from high-resolution respirometry in mouse, rat and Drosophila brain, ischemia and aging models. MitoFit Preprints 2023.10. https://doi.org/10.26124/mitofit:2023-0010
-:from the O2k-Network »[[AT Innsbruck Oroboros]]« and »[[LV Riga Liepins E]]«
-|}
-----
-*'''Dec- 07 Th'''
-:{|
-| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
-|'''"(…) L-Erg [L-Ergothioneine] treatment prevented and delayed cystine lithiasis in a cystinuria mouse model by increasing urinary cystine solubility and restored kidney GSH content and OXPHOS function."''' <br>
-* Mayayo-Vallverdú C, López de Heredia M, Prat E, González L, Espino Guarch M, Vilches C, Muñoz L, Asensi MA, Serra C, Llebaria A, Casado M, Artuch R, Garrabou G, Garcia-Roves PM, Pallardó FV, Nunes V (2023) The antioxidant l-Ergothioneine prevents cystine lithiasis in the Slc7a9-/- mouse model of cystinuria [[Mayayo-Vallverdu 2023 Redox Biol|»Bioblast link«]]
-:from the O2k-Network »[[ES Barcelona Moren C]]« and »[[ES Barcelona Garcia-Roves PM]]«
-|}
-----
-*'''Dec- 08 Fr'''
-----
-'''<big>Next Week</big>'''
 Week 50
@@ Line 65: / Line 30: @@
 ----
 *'''Dec- 15 Fr'''
+----
+'''<big>Next Week</big>'''
+Week 51
+*'''Dec- 18 Mo'''
+:::: '''»[[SBC 2023 Goa IN]]«''' Dec 18-20
+:{|
+| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
+|''' Why add azide after ascorbate and TMPD when measuring Complex IV activity? '''<br>
+The O<sub><small>2</small></sub> flux measured after the titration of ascorbate and TMPD is due to both CIV activity and autooxidation of these compounds. By subsequently inhibiting CIV activity with azide, the O<sub><small>2</small></sub> flux due to autooxidation (chemical background) can be determined and subtracted from the initial measurement. <br>
+- »'''[[Complex IV]]'''«, »'''[[Chemical background]] '''«  <br>
+- communicated by »[[Grings Mateus]]« and »[[Timon-Gomez Alba]]«
+|}
+----
+*'''Dec- 19 Tu'''
+----
+*'''Dec- 20 We'''
+:{|
+| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
+|'''"SIRT4 [Sirtuin 4] knockdown increases mitochondrial capacity to oxidize fatty acids, decreasing LEAK respiration and further increasing mitochondrial elongation via its regulation of mitochondrial fusion."''' <br>
+* Noone J, Rochfort KD, O'Sullivan F, O'Gorman DJ (2023) SIRT4 is a regulator of human skeletal muscle fatty acid metabolism influencing inner and outer mitochondrial membrane-mediated fusion. [[Noone 2023 Cell Signal|»Bioblast link«]]
+:from the O2k-Network »[[US FL Orlando Goodpaster BH]]« and »[[IE Dublin O Gorman D]]«
+|}
+----
+*'''Dec- 21 Th'''
+----
+*'''Dec- 22 Fr'''
 ----