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Difference between revisions of "Template:Current week ecosystem agenda"

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{{Template:Science for Ukraine}}
{{Template:Science for Ukraine}}
  2024 Week 05
2024 Week 16
* '''Jan-29 Mo'''
 
:::: '''»[[E-mit Winter School 2024 Brixen IT]]«''' Jan 28 - Feb 02
* '''Apr-15 Mo'''  
:{|
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
|'''Do you observe either a zero or low raw O<sub>2</sub> signal when starting a measurement?'''<br>
Perform a test to evaluate whether this is related to an improperly positioned chamber or a faulty connection between the OroboPOS and the OroboPOS-Connector. <br>
- »'''[https://wiki.oroboros.at/index.php/Oxygen_signal#Raw_signal Oxygen signal]'''«<br>
- communicated by »[[Grings Mateus]]« and »[[Schmitt Sabine]]«
|}
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* '''Jan-30 Tu'''
* '''Apr-16 Tu'''  
:::: '''16:30  [[Gnaiger Erich|Erich Gnaiger]] presenting at [[E-mit Winter School 2024 Brixen IT]]''' - ''Coupling control and pathway control in mitochondrial high-resolution respirometry''
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* '''Jan-31 We'''  
* '''Apr-17 We'''  
:{|
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
|''' Can the S-pathway O<sub><small>2</small></sub> flux be derived by subtracting N-pathway O<sub><small>2</small></sub> flux from NS-pathway O<sub><small>2</small></sub> flux?'''<br>
No, the sum of the O<sub><small>2</small></sub> fluxes measured in the presence of NADH-linked substrates alone and succinate as the single substrate is typically higher than using a combination of all these substrates. This effect is described as incomplete additivity: <br>
- »'''[[Additive effect of convergent electron flow]]'''« <br>
- communicated by »[[Cardoso Luiza]]« and »[[Grings Mateus]]«
|}
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* '''Feb-01 Th'''  
* '''Apr-18 Th'''  
:{|
:{|
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
|''' ''“Doing the entire hands-on module from start to finish was the best for really “cementing” theory and hands-on application together.”'''''<br>
|''' How to store the POS overnight and up to several months? '''<br>
[[Cosgrove Richard]] from Eli Lilly Research Labs, on what he liked best on [[IOC162]]<br>
With the POS still in place, fill the O2k-chamber and receptacle of the loosely inserted stopper with 70 % EtOH, add the Cover-slip and switch off the O2K. <br>
- »'''[[O2k-Feedback]]'''«<br>
- »'''[[MiPNet19.03 O2k-cleaning and ISS]]'''«<br>
- communicated by »[[Leo Elettra]]« and »[[Grings Mateus]]«
|}
|}
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* '''Feb-02 Fr'''  
* '''Apr-19 Fr'''
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'''<big>Next Week</big>'''
'''<big>Next Week</big>'''
  2024 Week 06
  2024 Week 17


* '''Feb-05 Mo'''
* '''Apr-22 Mo'''
:{|
:{|
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
|'''"We demonstrated deficient platelet mitochondrial respiratory chain functions, oxidative phosphorylation (OXPHOS), and electron transfer (ET) capacity with complex I (CI)-linked substrates, and reduced [...] endogenous platelet coenzyme Q10 (CoQ10) concentration in UC [urothelial carcinoma] patients."''' <br>
|'''How can I evaluate the effect of one specific titration of a complex SUIT protocol?'''<br>
* Palacka P, Gvozdjáková A, Rausová Z, Kucharská J, Slopovský J, Obertová J, Furka D, Furka S, Singh KK, Sumbalová Z (2021) Platelet mitochondrial bioenergetics reprogramming in patients with urothelial carcinoma. [[Palacka 2021 Int J Mol Sci|»Bioblast link«]]
Flux control efficiencies express the change in respiration after a single step, in which there is a change in a metabolic control variable.<br>
:from the O2k-Network »[[SK Bratislava Sumbalova Z]]«
- »'''[[Flux control efficiency]]'''«, »'''[[Metabolic control variable]]'''«<br>
- communicated by »[[Cardoso Luiza]]« and »[[Baglivo Eleonora]]«  
|}
|}
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* '''Feb-06 Tu'''  
* '''Apr-23 Tu'''  
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* '''Feb-07 We'''  
* '''Apr-24 We'''  
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* '''Feb-08 Th'''  
* '''Apr-25 Th'''
 
:{|
:{|
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
|'''Can I use the same stock solutions for all reagents for different O2k-chamber volumes?'''<br>
|'''"Our results further enhance the understanding and relevance of bioenergetic function in liver ischemia and transplantation and provide the basis for further consideration of these parameters as biomarkers in LT [liver transplantation]."''' <br>
"For some reagents, the concentration of the stock solution differs between the 2.0-mL and the 0.5-mL chamber (O2k-sV-Module) to facilitate a precise volume titration."<br>
* Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. [[Meszaros_2024_Transpl_Int|»Bioblast link«]]
-»'''[[MiPNet09.12 O2k-Titrations]]'''«<br>
:from the O2k-Network »[[AT Innsbruck Schneeberger S]] and [[AT Innsbruck Oroboros]]«
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«
|}  
|}
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* '''Feb-09 Fr'''  
* '''Apr-26 Fr'''
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Revision as of 14:02, 15 April 2024

Gentle Science
Oroboros declares solidarity against the Russian aggression-war in Ukraine and against all aggression-wars worldwide. -  »More details
A future for Ukraine is the future of its science
2024 Week 16
  • Apr-15 Mo
O2k-Open SupportInfo: improve Do you observe either a zero or low raw O2 signal when starting a measurement?

Perform a test to evaluate whether this is related to an improperly positioned chamber or a faulty connection between the OroboPOS and the OroboPOS-Connector.
- »Oxygen signal«
- communicated by »Grings Mateus« and »Schmitt Sabine«


  • Apr-16 Tu

  • Apr-17 We

  • Apr-18 Th
O2k-Open SupportInfo: improve How to store the POS overnight and up to several months?

With the POS still in place, fill the O2k-chamber and receptacle of the loosely inserted stopper with 70 % EtOH, add the Cover-slip and switch off the O2K.
- »MiPNet19.03 O2k-cleaning and ISS«
- communicated by »Leo Elettra« and »Grings Mateus«


  • Apr-19 Fr

Next Week

2024 Week 17
  • Apr-22 Mo
MitoPedia
How can I evaluate the effect of one specific titration of a complex SUIT protocol?

Flux control efficiencies express the change in respiration after a single step, in which there is a change in a metabolic control variable.
- »Flux control efficiency«, »Metabolic control variable«
- communicated by »Cardoso Luiza« and »Baglivo Eleonora« 


  • Apr-23 Tu

  • Apr-24 We

  • Apr-25 Th
O2k-Publications in the MiPMap "Our results further enhance the understanding and relevance of bioenergetic function in liver ischemia and transplantation and provide the basis for further consideration of these parameters as biomarkers in LT [liver transplantation]."
  • Meszaros AT, Weissenbacher A, Schartner M, Egelseer-Bruendl T, Hermann M, Unterweger J, Mittelberger C, Reyer BA, Hofmann J, Zelger BG, Hautz T, Resch T, Margreiter C, Maglione M, Komlódi T, Ulmer H, Cardini B, Troppmair J, Öfner D, Gnaiger E, Schneeberger S, Oberhuber R (2024) The predictive value of graft viability and bioenergetics testing towards the outcome in liver transplantation. »Bioblast link«
from the O2k-Network »AT Innsbruck Schneeberger S and AT Innsbruck Oroboros«

  • Apr-26 Fr