Talk:COST Action MitoEAGLE

COST Actions approved 2015

CA connections to MITOEAGLE

• CA COST Action CA15110 - Harmonising standardisation strategies to increase efficiency and competitiveness of European life-science research

Selected CA topics

• CA15115 Mining the European Anthroposphere 17

• CA15120 Open Multiscale Systems Medicine 22

• CA15123 The European research network on types for programming and verification 25

• CA15129 Diagnosis, Monitoring and Prevention of Exposure‐Related Noncommunicable Diseases 31

• CA15131 ABM & Training of Laboratory Non‐human Primates & Large Laboratory Animals 33

• CA15132 The comet assay as a human biomonitoring tool 34

• CA15133 The Biogenesis of Iron‐sulfur Proteins: from Cellular Biology to Molecular Aspects 35

Circulars towards the 1st MC meeting

2016-03-21 MITOEAGLE Management Committee nominations

Dear colleague,

We would like to follow-up regarding the nominations to the Management Committee of the COST Action MITOEAGLE.

The Scientific Committee suggested that the proposed Action must develop and implement specific plans to increase the involvement of Early Career Investigators and for maintaining and monitoring gender balance. Furthermore, we will need a balance of Participants from all the Working Groups in the MC, so that all WGs are represented well in the course of the Action. For more information, see » Join the COST Action CA15203 MITOEAGLE.

Therefore, please ask your COST National Coordinator (CNC) to take this into consideration when nominating the MC Members and Substitutes. To achieve an optimum balance in choosing your MC Members, it may be best practice to list all national COST Participants when contacting your CNC. For the list of participants, see

» MITOEAGLE-Feedback

» MITOEAGLE network

Your feedback will be summarized here: » MITOEAGLE-Feedback

Best regards,

Erich and Sandra

Ao. Univ.-Prof. Dr. Erich Gnaiger

Medical University of Innsbruck

Department of Visceral, Transplant and Thoracic Surgery

D. Swarovski Research Laboratory

Mitochondrial Physiology

Email: [email protected] http://www.mitofit.org

Sandra Fleischmann, MSc MSc, Project Manager

OROBOROS INSTRUMENTS high-resolution respirometry

Schöpfstrasse 18

A-6020 Innsbruck

Austria

T +43 512 566796 | F +43 512 566796 20

Email: [email protected] http://www.oroboros.at

2016-03-02 COST MITOEAGLE - Next steps

Dear colleague,

We would like to let you know that the Memorandum of Understanding (MoU) of the COST Action MITOEAGLE has been published on e-COST: » http://www.cost.eu/COST_Actions/ca/CA15203.

1. If you are interested in being part of the Management Committee (MC), please contact us with a very brief outline of your active role in the Action: choice of Working Group(s) - MITOEAGLE#Working_Groups. We will need a balance of MC members in the working groups and management tasks.

2. Even if you are listed in the Network of Proposers, you will have to contact your COST National Coordinator (CNC) who will be responsible for your participation in the MITOEAGLE Action and the nominations to the Management Committee.

» COST Action MITOEAGLE

» Join the COST Action CA15203 MITOEAGLE

As soon as the MoU has been accepted by five Countries through their respective CNCs, the Action can officially start. The COST Association will organize the kick-off meeting of our Action.

If you have any further questions, don't hesitate to contact us.

Best regards,

Erich and Sandra

Ao. Univ.-Prof. Dr. Erich Gnaiger

Medical University of Innsbruck

Department of Visceral, Transplant and Thoracic Surgery

D. Swarovski Research Laboratory

Mitochondrial Physiology

Email: [email protected] http://www.mitofit.org

Sandra Fleischmann, MSc MSc, Project Manager

OROBOROS INSTRUMENTS high-resolution respirometry

Schöpfstrasse 18

A-6020 Innsbruck

Austria

T +43 512 566796 | F +43 512 566796 20

Email: [email protected] http://www.oroboros.at

Approval

2016-02-15 COST MITOEAGLE was approved

Dear colleague,

We are delighted to inform you that our COST Action proposal “Mitochondrial mapping: Evolution - Age - Gender - Lifestyle - Environment (MITOEAGLE)” was approved by the COST Committee of Senior Officials. The very positive evaluation of MITOEAGLE (» MITOEAGLE evaluation highlights) is truly overwhelming, especially taking into consideration that the success rate of COST applications submitted by the September collection date was only 10%.

We would like to thank you very much for supporting this Action and inform you that we have re-opened the MITOEAGLE website: » MITOEAGLE.

We will follow up with next steps ASAP and are looking forward to a prosperous collaboration!

Best regards,

Sandra

Sandra Fleischmann, MSc MSc

Chief Web Officer (CWO) and Project Manager

OROBOROS INSTRUMENTS

high-resolution respirometry

Schöpfstrasse 18, A-6020 Innsbruck, Austria

T +43 512 566796 | F +43 512 566796 20

Email: [email protected] | http://www.oroboros.at

Partner circulars Proposal phase

2015-02-27 COST MITOEAGLE

Dear COST Action Participants,

We would like to welcome you to MITOEAGLE. We are overwhelmed by the numerous responses (46 groups) and the great interest in this COST Action, which encourages us in our ambitions.

For up-to-date information on participants and Working Groups, please check the following links:

» http://www.bioblast.at/index.php/MitoGlobal_EAGLE#EAGLE_consortium

» http://www.bioblast.at/index.php/COST_MITOEAGLE (*)

At a first glance, the four Working Groups (WGs) seem to be appropriate for the consortium. Feel free to update or change your selection of the WGs you will join, particularly when the WGs will be elaborated more precisely. Please note that we have changed the focus from “human and mouse models” to “human and rodent models”. Furthermore, we would like to ask you, whether you consider the specific focus on gender to be appropriate or if we should keep a general balance for all EAGLE topics (Evolution - Age - Gender - Lifestyle – Environment)?

In order to participate in a COST Action, participants will need to register in the COST electronic database, e-COST, with affiliation profile and CV. Multiple participants may register for each institution. Registration is very simple and straightforward and can be found on:

» https://e-services.cost.eu/?module=user&action=loginForm&userParam%5BrequestedURI%5D=%2F

We would like to ask you to forward us the name of your groups' main contact person (first name, last name) and the corresponding e-mail used in the e-COST registration within the next week. ‘Proposers’ will then be invited among the main contact persons through the e-COST submission tool. ‘Proposers’ have to finally accept the invitation by following the link in the invitation e-mail.

Sandra will manage these further steps in our COST Action application.

Best regards,

Erich and Sandra

Erich Gnaiger, Ao.Univ.-Prof., Ph.D.

Medical University of Innsbruck

Department of Visceral, Transplant and Thoracic Surgery

D. Swarovski Research Laboratory

A-6020 Innsbruck, Austria

Link: http://www.bioblast.at/index.php/MitoGlobal_EAGLE

Contact: [email protected]; [email protected]

Disclosure: Dr Erich Gnaiger is founder and CEO of OROBOROS INSTRUMENTS – www.oroboros.at

Originally listed Working groups (WG)

WG1. MITOEAGLE data base on gender and mt-function in health and disease

• Mainly published data from WG participants will be cataloged in the detail beyond the published record (anonymised data on individuals in addition to group averages; tabulated results in addition to figures; conversion to common SI units; comparability of normalization).
• Data management systems - diversity vs. unification to manage the MITOEAGLE biometrics database.
• Measures of mitochondrial respiratory function in human and rodent tissues, blood cells and cell lines will be structured according to the EAGLE background, with specific emphasis on gender-specific mt-function and gender medicine; joint publication.

WG2. Challenges on quality control for reference data in mitochondrial physiology

• Basic concepts and communication: Consolidation of concepts and nomenclature on mitochondrial respiratory states and control parameters; MitoPedia; joint publication.
• Laboratory standards: Protocols, technologies and standard procedures; data base on laboratory protocols.
• Reference data in mitochondrial physiology: Quality control, documentation, bioinformatics standards.

WG3. Inter-laboratory test and outreach

• An inter-laboratory ring test will be introduced in practice as a world-wide innovation in the field of mitochondrial respiratory physiology: design and implementation; reference sample dissemination; test protocol(s); data analysis; joint publication.
• Comparison of results between and within instrumental platforms.
• Logistics for extended future collaboration in Europe, North and South America, Asia, Australia and Africa.

WG4. Training and data sharing

• Recommendations for quality control, data reporting and data sharing beyond the published record.
• Concepts on Open Access and institutionalized service for data management, data mining and health-care conforming standards of data interpretation.
• Summary on strategic dissemination and education programme for MitoGlobal EAGLE.

Partner invitation 2015-02-28

Dear colleagues:

A COST application MITOEAGLE is in preparation, following discussions over the past years at various meetings, on a global mitochondrial network. The project is called MITOEAGLE, for Evolution, Age, Gender, Lifestyle and Environment. COST Actions support networking, not primary research.

Four working groups (WG) are suggested – open for discussion and further elaboration:

• WG1. MITOEAGLE data base on gender and mt-function in health and disease
• WG2. Challenges on quality control for reference data in mitochondrial physiology
• WG3. Inter-laboratory test and outreach
• WG4. Training and data sharing

Further details: » http://www.bioblast.at/index.php/COST_MITOEAGLE

The deadline for submission is 2015 March 24. To get an idea, can you let us know if you are interested in the project in general, and which working groups you might be interested in participating? If you agree to be ‘on board’, we will add you to the list of the (informal) EAGLE consortium:

» http://www.bioblast.at/index.php/MitoGlobal_EAGLE

You may register in the COST electronic database, e-COST, with affiliation profile and CV. Multiple participants may register for each institution which is simple and straightforward:

» https://e-services.cost.eu/?module=user&action=loginForm&userParam%5BrequestedURI%5D=%2F

Best regards,

Erich

Erich Gnaiger, Ao.Univ.-Prof., Ph.D.

Medical University of Innsbruck

Department of Visceral, Transplant and Thoracic Surgery

D. Swarovski Research Laboratory

A-6020 Innsbruck, Austria

Link: http://www.bioblast.at/index.php/MitoGlobal_EAGLE

Disclosure: Dr Erich Gnaiger is founder and CEO of OROBOROS INSTRUMENTS – www.oroboros.at

Partner invitation 2015-02-24

Dear colleague:

The reason for this Email is to follow up on an idea discussed over the past year at various meetings all over the world, on a global mitochondrial network to bring together scattered data in the field of mitochondrial physiology and medicine.

The project is called MitoGlobal EAGLE or mtEAGLE, for Evolution, Age, Gender, Lifestyle and Environment. The attached summary of the mtEAGLE project is a first draft for a COST project proposal – open for discussion and further elaboration. COST Actions support networking, not primary research (see below).

In the attached draft, four working groups (WG) are suggested:

• WG1. mtEAGLE data base on gender and mt-function in health and disease
• WG2. Challenges on quality control for sharing data in mitochondrial physiology
• WG3. Interlaboratory test and outreach
• WG4. Training and data sharing

The deadline for submission is 2015 March 24. To get an idea, can you let me know if you are interested in the project in general, and which working groups you might be interested in participating?

I am looking forward to your feedback. If you agree and you are going to be ‘on board’, we would add you to the list of the (informal) EAGLE consortium:

» http://www.bioblast.at/index.php/MitoGlobal_EAGLE

Best wishes from Innsbruck,

Erich

Erich Gnaiger, Ao.Univ.-Prof., Ph.D.

Medical University of Innsbruck

Department of Visceral, Transplant and Thoracic Surgery

D. Swarovski Research Laboratory

A-6020 Innsbruck, Austria

Link: http://www.bioblast.at/index.php/MitoGlobal_EAGLE

Disclosure: Dr Erich Gnaiger is founder and CEO of OROBOROS INSTRUMENTS – www.oroboros.at

Some further COST information:

• I was involved as a participant in two COST projects, ‘Mitofood’ and more recently ‘Hypoxia sensing, signalling and adaptation’:

» http://www.cost.eu/COST_Actions/bmbs/Actions/TD0901

• COST Actions are networks centred around nationally funded research projects in fields that are of interest to at least five COST countries.
• The financial support averages EUR 130 000 per year for a four-year period. - http://www.cost.eu/COST_ActionsEarly Stage Researcher (ESR) - is a term used to define a researcher whose career spans less than 8 years between the date of the PhD/doctorate (or similar experience) and the date of involvement in the COST Action. Periods of career leave have to be added to this time span. COST approved a specific strategy for early stage researchers.