Superoxide dismutase

high-resolution terminology - matching measurements at high-resolution

Superoxide dismutase

Description

Mammalian superoxide dismutase (SOD) exists in three forms, of which the Mn-SOD occurs in mitochondria (mtSOD, SOD2; 93 kD homotetramer) and many bacteria, in contrast to the Cu-Zn forms of SOD (cytosolic SOD1, extracellular SOD3 anchored to the extracellular matrix and cell surface). Superoxide anion (O₂^•-) is a major reactive oxygen species (ROS) which is dismutated by SOD to oxygen and H₂O₂.

Abbreviation: SOD

Reference: Fridovich_1997_J Biol Chem

MitoPedia topics: Enzyme 

Application in fluorometry

• Add SOD for conversion of O₂^•- and measurement of H₂O₂ with Amplex Red.