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This page provides a simple browsing interface for finding entities described by a property and a named value. Other available search interfaces include the page property search, and the ask query builder.

Search by property

"%3ADescription%2FReduction-20of-20-5B-5Boxoglutarate-5D-5D-20%282OG-20or-20alpha-2Dketoglutarate%29-20to-20-27-27%272-2Dhydroxyglutarate-27-27%27-20%282HG%29-20is-20driven-20by-20NADPH.-202HG-20is-20also-20formed-20in-20side-20reactions-20of-20-5B-5Blactate-20dehydrogenase-5D-5D-20and-20-5B-5Bmalate-20dehydrogenase-5D-5D.-20Millimolar-202HG-20concentrations-20are-20found-20in-20some-20cancer-20cells-20compared-20to-20%2C-20whereas-20side-20activities-20of-20lactate-20and-20malate-20dehydrogenase-20form-20submillimolar-20s-2D2-2Dhydroxyglutarate-20%28s-2D2HG%29.-20However%2C-20even-20wild-2Dtype-20IDH1-20and-20IDH2%2C-20notably-20under-20shifts-20toward-20reductive-20carboxylation-20glutaminolysis-20or-20changes-20in-20other-20enzymes%2C-20lead-20to-20%E2%80%9Cintermediate%E2%80%9D-200.01%E2%80%930.1%E2%80%89mM-202HG-20levels%2C-20for-20example%2C-20in-20breast-20carcinoma-20compared-20with-20nanomolar-20concentrations-20in-20benign-20cells.-202HG-20is-20considered-20an-20important-20player-20in-20reprogramming-20metabolism-20of-20cancer-20cells." contains a listed "%" character as part of the property label and has therefore been classified as invalid.

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