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• O2k-Publications: Sepsis
  ...Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Diseases::Sepsis]] == O2k-Publications: Sepsis - Abstracts ==
  1 KB (193 words) - 15:48, 16 April 2018

Page text matches

• Correa 2015 Critical Care Horizon
  |title=Corrêa TD, Jakob SM, Takala J (2015) Mitochondrial function in sepsis. Critical Care Horizon 1:31-41 . ...criticalcarehorizons.com/wp-content/uploads/2040/06/mitochondrial-function-sepsis-FINAL.pdf Open Access PDF]
  1 KB (202 words) - 16:06, 7 November 2016
• Jeger 2013 Eur J Clin Invest
  ...eger V, Djafarzadeh S, Jakob SM, Takala J (2013) Mitochondrial function in sepsis. Eur J Clin Invest 43:532-42. ...cused review evaluates the evidence for impaired mitochondrial function in sepsis.
  2 KB (305 words) - 15:46, 27 April 2015
• Eyenga 2022 Cells
  ...SS (2022) Regulation of oxidative phosphorylation of liver mitochondria in sepsis. Cells 11:1598. https://doi.org/10.3390/cells11101598 ...enues to improve the functions of cytochrome c oxidase and ATP synthase in sepsis.
  2 KB (236 words) - 23:20, 23 April 2023
• Kohoutova 2018 Physiol Res
  ..., Kuncová J (2018) Variability of mitochondrial respiration in relation to sepsis-induced multiple organ dysfunction. Physiol Res 67:577-92. ...d minimized by the use of appropriate experimental models resembling human sepsis, wider use of larger animal species in preclinical studies, more detailed m
  2 KB (290 words) - 16:03, 25 March 2019
• Frost S
  |topics=Hyperoxic sepsis, COLD sepsis
  634 bytes (76 words) - 15:26, 13 February 2018
• Jang 2018 Shock
  ...tions in mitochondrial function in blood cells obtained from patients with sepsis presenting to an emergency department. Shock 51:580-84. ...completely understood pathophysiology of the dysregulated host response in sepsis.
  2 KB (343 words) - 14:37, 5 July 2023
• Doerrier 2015 Thesis
  |title=Doerrier C (2015) Estudio bioenergetica mitochondrial en la sepsis experimental y efecto protector de la Melatonina. Doctoral Thesis p154. |abstract=Sepsis, a systemic inflammatory response of the organism against an infection,
  2 KB (326 words) - 15:11, 23 January 2019
• Horak 2020 Front Immunol
  ...engl M, Matejovic M (2020) Evaluation of mesenchymal stem cell therapy for sepsis: a randomized controlled porcine study. Front Immunol 11:126. ...n adequately studied in large-animal models with better relevance to human sepsis.
  3 KB (363 words) - 19:32, 14 February 2022
• Sims 2014 FASEB J
  ...P (2014) Mitochondrial superoxide generation in the rat pup kidney during sepsis. FASEB J 28:1063.7. ...the mitochondrial complexes at these early time points studied. Therefore, sepsis does not appear to cause severe mitochondrial dysfunction in rat pups despi
  2 KB (271 words) - 15:00, 28 March 2018
• O2k-Publications: Sepsis
  ...Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Diseases::Sepsis]] == O2k-Publications: Sepsis - Abstracts ==
  1 KB (193 words) - 15:48, 16 April 2018
• Ortiz 2014 J Pineal Res
  ...eficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of iNOS and preservation of nNOS. J Pineal Res 56:71-81. ...t during sepsis and further support the beneficial actions of melatonin in sepsis.
  2 KB (358 words) - 08:05, 21 February 2020
• Leduc-Gaudet 2021 bioRxiv
  ...D, Huck L, Sandri M, Gouspillou G, Hussain SNA (2021) Role of autophagy in sepsis-induced skeletal muscle dysfunction, whole-body metabolism, and survival. b ...mpacts survival. Induction of autophagy in skeletal muscles in response to sepsis thus represents a protective mechanism.
  3 KB (373 words) - 14:13, 27 October 2021
• Al-Obeidallah 2021 J Pers Med
  ...temperature allow early discrimination between porcine peritonitis-induced sepsis and peritonitis-induced septic shock. J Pers Med 11:164. ..., hemodynamical parameters and body temperature discriminate early between sepsis and septic shock in a clinically relevant porcine model. Early pronounced a
  2 KB (305 words) - 17:29, 8 March 2021
• Weiss 2022 Shock
  ...rial measurements in peripheral blood mononuclear cells from children with sepsis. Shock 57:630-8. https://doi.org/10.1097/SHK.0000000000001903 ...on PBMC mitochondrial respiration and content in children with and without sepsis.
  3 KB (403 words) - 22:49, 12 September 2023
• Doerrier 2014 Life Sci
  ...ata showed that melatonin maintains liver mitochondrial homeostasis during sepsis, but neither the mechanisms underlying mitochondrial dysfunction nor the ta ...C57BL/6 mice at early and late phases of sepsis, i.e., at 8 and 24 h after sepsis induction.
  3 KB (352 words) - 00:49, 10 February 2020
• Sjoevall 2013 Crit Care
  ...all F, Morota S, Persson J, Hansson Magnus J, Elmer E (2013) Patients with sepsis exhibit increased mitochondrial respiratory capacity in peripheral blood im ...ated mitochondrial respiration in peripheral blood immune cells (PBICs) in sepsis patients during the first week after admission to the intensive care unit (
  2 KB (331 words) - 23:09, 29 February 2020
• Jang 2019 Crit Care Med
  ...aion and mitochondrial function in blood cells obtained from patients with sepsis. Crit Care Med. ...and peripheral blood mononuclear cells (PBMCs) obtained from patients with sepsis and healthy controls.
  3 KB (459 words) - 14:37, 5 July 2023
• Patil 2014 Am J Physiol Renal Physiol
  ...ochondrial respiratory complexes and manganese superoxide dismutase during sepsis: mitochondria targeted antioxidant mitigates injury. Am J Physiol Renal Phy ...ased 96-hour survival rate from 40% in untreated septic mice to 80%. Thus, sepsis causes sustained inactivation of three mitochondrial targets that can lead
  2 KB (320 words) - 09:42, 8 November 2016
• Larche 2006 J Am Coll Cardiol
  ...ere R (2006) Inhibition of mitochondrial permeability transition prevents sepsis-induced myocardial dysfunction and mortality. J Am Coll Cardiol 48:377-85. ...dysfunction is causative of sepsis sequelae, a mouse model of peritonitis sepsis induced by cecal ligation and perforation. Inhibition of mitochondrial perm
  3 KB (360 words) - 11:50, 22 December 2020
• Doerrier 2016 Mitochondrion
  ...ized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochon ...o identify properly respiratory deficits and specific melatonin effects in sepsis.
  2 KB (272 words) - 04:35, 19 July 2022
• Manfredini 2019 Clin Sci (Lond)
  ...dysfunction is associated with long-term cognitive impairment in an animal sepsis model. Clin Sci (Lond) 133:1993-2004. ...al function and long-term cognitive impairment in an experimental model of sepsis.
  3 KB (360 words) - 16:59, 13 May 2020
• Zhang 2018 Mil Med Res
  ...(2018) Potential therapy strategy: targeting mitochondrial dysfunction in sepsis. Mil Med Res 5:41. https://doi.org/10.1186/s40779-018-0187-0 ...etermine the major mitochondrial disorders from morphology to functions in sepsis. In the following, several clinical or pre-clinical assays for monitoring m
  2 KB (289 words) - 11:08, 22 March 2023
• Kohoutova 2019 Crit Care Med
  ...attenuates multiple organ dysfunction in resuscitated porcine progressive sepsis. Crit Care Med 47:e461-69. ...rve stimulation in a clinically-relevant large animal model of progressive sepsis.
  3 KB (355 words) - 19:42, 17 February 2022
• Volt 2014 Abstract The 2014 Ageing Summit
  ...in on the age-dependent dysregulation of the Nf-Kb/Nlrp3 activation during sepsis. ...s support NLRP3 inflammasome as a novel molecular signaling pathway during sepsis and indentify it as a main target for the anti-inflammatory action of melat
  2 KB (288 words) - 17:34, 7 November 2016
• Cheng 2016 Nat Immunol
  ...defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis. Nat Immunol 17:406-13. ...suggested that metabolic processes might represent a therapeutic target in sepsis.
  2 KB (303 words) - 04:13, 12 February 2020
• Weiss 2021 Crit Care Explor
  ..., Collman RG (2021) Decreased intestinal microbiome diversity in pediatric sepsis: a conceptual framework for intestinal dysbiosis to influence immunometabol ...ain fatty acids. We explored whether intestinal dysbiosis in children with sepsis leads to changes in microbial-derived short-chain fatty acids in plasma and
  3 KB (418 words) - 09:31, 9 July 2021
• Loftus 2017 BMJ Open
  ...tocols and standard operating procedures for a prospective cohort study of sepsis in critically ill surgical patients. BMJ Open 7:e015136. ...istent inflammation, immunosuppression and catabolism syndrome (PICS). The Sepsis and Critical Illness Research Center (SCIRC) was created to provide a platf
  3 KB (386 words) - 17:40, 27 November 2017
• Jang 2016 J Intensive Care Med
  ...2016) Measurement of mitochondrial respiration and motility in acute care: sepsis, trauma, and poisoning. J Intensive Care Med 32:86-94. ...l utility. Treatment of commonly encountered disease of acute care such as sepsis, trauma, and poisoning often relies on clinical diagnosis and therapy guide
  2 KB (252 words) - 23:26, 29 February 2020
• Lancel 2009 J Pharmacol Exp Ther
  ...B, Motterlini R, Neviere R (2009) Carbon monoxide rescues mice from lethal sepsis by supporting mitochondrial energetic metabolism and activating mitochondri ...) in biological systems have emerged as a potential adjunctive therapy for sepsis via their antioxidant, anti-inflammatory, and antiapoptotic effects. The ro
  3 KB (359 words) - 11:49, 22 December 2020
• Hara 2013 Eur J Anaesthesiol
  ...Uchino H (2013) Early brain mitochondrial dysfunction in a mouse model of sepsis: 7AP4‐9. Eur J Anaesthesiol 30,112-112. ...the temporal dynamics of brain mitochondrial function in a mouse model of sepsis.
  3 KB (428 words) - 13:45, 7 March 2020
• Weiss 2022 J Cell Mol Med
  ...gh which butyrate may help to mitigate the immuno-inflammatory response in sepsis. |keywords=Human immunology, Immunometabolism, Metabolism, Mitochondria, Sepsis
  2 KB (275 words) - 14:13, 28 November 2022
• Luther 2023 Am J Physiol Renal Physiol
  ...A, Frithiof R (2023) Renal mitochondrial dysfunction in ovine experimental sepsis associated acute kidney injury. https://doi.org/10.1152/ajprenal.00294.2022 ...of experiment and assessed ''in vitro'' with high resolution respirometry. Sepsis markedly reduced creatinine clearance and the relation between sodium trans
  3 KB (383 words) - 16:36, 2 May 2023
• Rutai 2019 Crit Care
  ...019) Potential role of endothelin receptors in the therapy of experimental sepsis. Crit Care. ...microcirculatory and mitochondrial respiration parameters in experimental sepsis.
  3 KB (365 words) - 14:50, 3 April 2019
• Karlsson 2016 Shock
  ...and tissue-specific mitochondrial respiratory response in a mouse model of sepsis-induced multiple organ failure. Shock 45:404-10. ...ggests a diverse and tissue-specific mitochondrial respiratory response to sepsis. The brain displayed an early impaired mitochondrial respiratory efficiency
  2 KB (351 words) - 13:40, 7 March 2020
• Preau 2014 Thesis University Lille
  ...yocardial dysfunction. Septic cardiomyopathy appears in the early phase of sepsis and is associated with fatal outcome. Complete recovery of myocardial funct sepsis that is suggested to postpone myocardium recovery. The first aim of the stu
  2 KB (291 words) - 09:51, 8 November 2016
• Wu 2023 Int Immunopharmacol
  |title=Wu F, Zhang YT, Teng F, Li HH, Guo SB (2023) S100a8/a9 contributes to sepsis-induced cardiomyopathy by activating ERK1/2-Drp1-mediated mitochondrial fis ...a9 may be a promising therapeutic strategy to prevent SIC in patients with sepsis.
  3 KB (372 words) - 17:08, 19 January 2023
• Sjoevall 2014 PLoS One
  ...Magnus J, Elmer E (2014) Cytokine and nitric oxide levels in patients with sepsis - temporal evolvement and relation to platelet mitochondrial respiratory fu ...d anti-inflammatory cytokines as well as NO plasma levels in patients with sepsis.
  3 KB (400 words) - 12:22, 16 September 2021
• MacMillan-Crow 2018 Intern Med Rev (Wash D C)
  ...ndrial injury but greater mortality using a comorbid model of experimental sepsis. Intern Med Rev (Wash D C) 4. ...in females. Our results suggest that the CLP nephrectomy comorbid model of sepsis may be an appropriate model to study gender differences a select group of p
  2 KB (354 words) - 11:35, 8 August 2019
• Halbach 2019 Am J Physiol Regul Integr Comp Physiol
  ...19) Early hyperbaric oxygen therapy improves survival in a model of severe sepsis. Am J Physiol Regul Integr Comp Physiol 317:R160-R168. ...after exposure to HBOT. Early HBOT could be of benefit in the treatment of sepsis and the protective mechanism may be related to a reduction in the systemic
  2 KB (378 words) - 12:25, 9 July 2019
• Sjoevall 2010 Crit Care
  ...espiration is negatively associated with clinical outcome in patients with sepsis. Crit Care 14:R214. ...al changes in platelet mitochondrial respiratory function in patients with sepsis during the first week after disease onset.
  3 KB (486 words) - 13:22, 27 December 2021
• Koenemann 2014 Dissertation
  ...en sollte [8]. Die Hyperglykämie kommt bei dem schweren Stress, der in der Sepsis auftritt, durch das Zusammenwirken von vermehrter Ausschüttung von katabol |diseases=Sepsis
  1 KB (150 words) - 14:56, 13 November 2017
• Markova 2017 MiP2017
  |title=[[Image:MarkovaM.jpg|left|90px|Michaela Markova]] Porcine sepsis and associated myocardial depression. ...n were addressed in a clinically relevant, large animal (porcine) model of sepsis and septic shock.
  4 KB (489 words) - 09:32, 13 October 2017
• Yan 2019 Int Immunopharmacol
  ...g J, Wang Y, Chen H, Xie K, Yu Y (2019) Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner. Int Immunopharmacol 71:6 ...gas inhalation for 3 h may serve as an effective therapeutic strategy for sepsis-induced liver injury through the regulation of FUNDC1-dependent mitophagy.
  3 KB (394 words) - 15:09, 21 March 2019
• Hara N
  |topics=Sepsis, mitochondrial dysfunction
  360 bytes (38 words) - 15:27, 13 February 2018
• Hwang 2021 Crit Care
  ...ases involving mitochondrial dysfunction, but it has never been tested for sepsis. ...the isolated mitochondria. We conducted both ''in vivo'' and ''in vitro'' sepsis studies. We investigated the effects of intravenous mitochondrial transplan
  3 KB (389 words) - 19:18, 12 January 2021
• Paumelle 2019 J Hepatol
  ..., Staels B (2019) Hepatic PPARα is critical in the metabolic adaptation to sepsis. J Hepatol 70:963-73. ...sm and inflammation. However, the role of hepatic PPARα in the response to sepsis is unknown.
  3 KB (520 words) - 11:47, 22 December 2020
• Correa 2012 Crit Care Med
  ...valuate how the delay in starting resuscitation influences the severity of sepsis and the treatment needed to achieve hemodynamic stability. ...tation on disease severity, need for resuscitation, and the development of sepsis-associated organ and mitochondrial dysfunction.
  3 KB (393 words) - 17:26, 9 November 2017
• Sjövall 2013 Thesis Lund University - Sweden
  |title=Sjövall F (2013) Mitochondrial function in sepsis - temporal evolvement of respiratory capacity in human blood cells. Thesis |diseases=Sepsis
  4 KB (603 words) - 16:07, 13 November 2017
• McCann 2020 Metabolites
  ...stimating platelet mitochondrial oxygen consumption rates in patients with sepsis. Metabolites 10:E139. ...directly estimate platelet mitochondrial oxygen consumption rate (mOCR) in sepsis patients.
  2 KB (293 words) - 12:36, 16 September 2021
• Herminghaus 2016 Abstract MitoFit Science Camp 2016
  ...patic but not colonic mitochondrial function similar to moderate abdominal sepsis. ...d colonic mitochondrial function after sterile laparotomy and by abdominal sepsis in the time course of 96 hours.
  3 KB (475 words) - 17:24, 7 November 2016

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