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From Bioblast
 YearReferenceMammal and modelTissue and cellStressDiseases
Ost 2020 EMBO Rep2020Ost M, Igual Gil C, Coleman V, Keipert S, Efstathiou S, Vidic V, Weyers M, Klaus S (2020) Muscle-derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress. EMBO Rep 21:e48804.MouseSkeletal muscle
Catalan-Garcia 2020 J Clin Med2020Catalán-García M, García-García FJ, Moreno-Lozano PJ, Alcarraz-Vizán G, Tort-Merino A, Milisenda JC, Cantó-Santos J, Barcos-Rodríguez T, Cardellach F, Lladó A, Novials A, Garrabou G, Grau-Junyent JM (2020) Mitochondrial dysfunction: A common hallmark underlying comorbidity between sIBM and other degenerative and age-related diseases. J Clin Med 9:E1446.HumanFibroblastAlzheimer's
Diabetes
Myopathy
MitoEAGLE muscle 12020Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM (2020) Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers. - Updated: 2020-03-08HumanSkeletal muscle
Luevano-Martinez 2020 FEBS Lett2020Luévano-Martínez LA, Girard RMBM, Alencar MB, Silber AM (2020) ATP regulates the activity of an alternative oxidase in Trypanosoma brucei. FEBS Lett [Epub ahead of print].Protists
Simard 2020b Metabolites2020Simard CJ, Touaibia M, Allain EP, Hebert-Chatelain E, Pichaud N (2020) Role of the mitochondrial pyruvate carrier in the occurrence of metabolic inflexibility in Drosophila melanogaster exposed to dietary sucrose. Metabolites 10:E411.Drosophila
Hayes 2020 Nutrients2020Hayes P, Fergus C, Ghanim M, Cirzi C, Burtnyak L, McGrenaghan CJ, Tuorto F, Nolan DP, Kelly VP (2020) Queuine micronutrient deficiency promotes Warburg metabolism and reversal of the mitochondrial ATP synthase in HeLa cells. Nutrients 12:E871.HumanHeLaCancer
Oliveira 2020 Anim Reprod2020Oliveira VS, Castro AJG, Domingues JT, Souza AZP, Scheffer DL, Latini A, Soares CHL, Van Der Kraak G, Silva FRMB (2020) A brazilian pulp and paper mill effluent disrupts energy metabolism in immature rat testis and alters sertoli cell secretion and mitochondrial activity. Anim Reprod 17:e20190116.RatGenital
Kupats 2020 Oxid Med Cell Longev2020Kupats E, Stelfa G, Zvejniece B, Grinberga S, Vavers E, Makrecka-Kuka M, Svalbe B, Zvejniece L, Dambrova M (2020) Mitochondrial-protective effects of R-phenibut after experimental traumatic brain injury. Oxid Med Cell Longev 2020:9364598.MouseNervous systemOther
Baxter 2020 Elife2020Baxter M, Voronkov M, Poolman T, Galli G, Pinali C, Goosey L, Knight A, Krakowiak K, Maidstone R, Iqbal M, Zi M, Prehar S, Cartwright EJ, Gibbs J, Matthews LC, Adamson AD, Humphreys NE, Rebelo-Guiomar P, Minczuk M, Bechtold DA, Loudon A, Ray D (2020) Cardiac mitochondrial function depends on BUD23 mediated ribosome programming. Elife 9:e50705.MouseHeart
Silaidos 2020 Mitochondrion2020Silaidos C, Grube J, Muley C, Eckert GP (2020) Time-dependent melatonin secretion is associated with mitochondrial function in peripheral blood mononuclear cells (PBMC) of male volunteers. Mitochondrion 53:21-29.HumanBlood cells
Zhang 2020 Acta Pharmacol Sin2020Zhang L, Wang YN, Ju JM, Shabanova A, Li Y, Fang RN, Sun JB, Guo YY, Jin TZ, Liu YY, Li TY, Shan HL, Liang HH, Yang BF (2020) Mzb1 protects against myocardial infarction injury in mice via modulating mitochondrial function and alleviating inflammation. Acta Pharmacol Sin 42:691-700.MouseHeartCardiovascular
Mahul-Mellier 2020 Proc Natl Acad Sci U S A2020Mahul-Mellier AL, Burtscher J, Maharjan N, Weerens L, Croisier M, Kuttler F, Leleu M, Knott GW, Lashuel HA (2020) The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration. Proc Natl Acad Sci U S A 117:4971-82.MouseNervous systemParkinson's
Plecita-Hlavata 2020 Antioxid Redox Signal2020Plecitá-Hlavatá L, Engstová H, Holendová B, Tauber J, Špaček T, Petrásková L, Křen V, Špačková J, Gotvaldová K, Ježek J, Dlasková A, Smolková K, Ježek P (2020) Mitochondrial superoxide production decreases on glucose-stimulated insulin secretion in pancreatic β cells due to decreasing mitochondrial matrix NADH/NAD+ ratio. Antioxid Redox Signal 33:789-815.RatIslet cell;pancreas;thymus
Assis-de-Lemos 2020 Curr Protoc Toxicol2020Assis-de-Lemos G, Ledur PF, Karmirian K, Rehen SK, Galina A (2020) A protocol to study mitochondrial function in human neural progenitors and iPSC-derived astrocytes. Curr Protoc Toxicol 85:e97.HumanNervous system
Kuffner 2020 Cells2020Kuffner K, Triebelhorn J, Meindl K, Benner C, Manook A, Sudria-Lopez D, Siebert R, Nothdurfter C, Baghai TC, Drexler K, Berneburg M, Rupprecht R, Milenkovic VM, Wetzel CH (2020) Major depressive disorder is associated with impaired mitochondrial function in skin fibroblasts. Cells 9:884. doi: 10.3390/cells9040884HumanFibroblastOther
Alahmad 2020 EMBO Mol Med2020Alahmad A, Nasca A, Heidler J, Thompson K, Oláhová M, Legati A, Lamantea E, Meisterknecht J, Spagnolo M, He L, Alameer S, Hakami F, Almehdar A, Ardissone A, Alston CL, McFarland R, Wittig I, Ghezzi D, Taylor RW (2020) Bi-allelic pathogenic variants in NDUFC2 cause early-onset Leigh syndrome and stalled biogenesis of complex I. EMBO Mol Med 12:e12619.HumanFibroblastNeurodegenerative
Gruenig 2020 Biochem Pharmacol2020Grünig D, Szabo L, Marbet M, Krähenbühl S (2020) Valproic acid affects fatty acid and triglyceride metabolism in HepaRG cells exposed to fatty acids by different mechanisms. Biochem Pharmacol 177:113860.MouseLiver
Irion 2020 Stem Cells Int2020Irion CI, Martins EL, Christie MLA, de Andrade CBV, de Moraes ACN, Ferreira RP, Pimentel CF, Suhett GD, Campos de Carvalho AC, Lindoso RS, Vieyra A, Galina A, Goldenberg RCS (2020) Acute myocardial infarction reduces respiration in rat cardiac fibers, despite adipose tissue mesenchymal stromal cell transplant. Stem Cells Int 2020:4327965 .RatHeartCardiovascular
Anand 2020 Toxicol In Vitro2020Anand CR, Bhavya B, Jayakumar K, Harikrishnan VS, Gopala S (2020) Inorganic nitrite alters mitochondrial dynamics without overt changes in cell death and mitochondrial respiration in cardiomyoblasts under hyperglycemia. Toxicol In Vitro 70:105048.RatHeartDiabetes
Obesity
Oellermann 2020 Sci Rep2020Oellermann M, Hickey AJR, Fitzgibbon QP, Smith G (2020) Thermal sensitivity links to cellular cardiac decline in three spiny lobsters. Sci Rep 10:202.CrustaceansHeartTemperature
Piel 2020 PLoS One2020Piel S, Chamkha I, Dehlin AK, Ehinger JK, Sjövall F, Elmér E, Hansson MJ (2020) Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose. PLoS One 15:e0231173.HumanLiver
Platelet
Brum 2020 Mol Neurobiol2020Brum EDS, Fialho MFP, Fischer SPM, Hartmann DD, Gonçalves DF, Scussel R, Machado-de-Ávila RA, Dalla Corte CL, Soares FAA, Oliveira SM (2020) Relevance of mitochondrial dysfunction in the reserpine-induced experimental fibromyalgia model. Mol Neurobiol 57:4202-17.MouseSkeletal muscle
Nervous system
Other
Zavadskis 2020 Pharmaceutics2020Zavadskis S, Weidinger A, Hanetseder D, Banerjee A, Schneider C, Wolbank S, Marolt Presen D, Kozlov AV (2020) Effect of diphenyleneiodonium chloride on intracellular reactive oxygen species metabolism with emphasis on NADPH oxidase and mitochondria in two therapeutically relevant human cell types. Pharmaceutics 13:E10.HumanOther cell linesOxidative stress;RONS
Lara-Marqueza 2020 J Funct Foods2020Lara-Márquez M, Báez-Magaña M, Raymundo-Ramos C, Spagnuolo PA, Macías-Rodríguez L, Salgado-Garciglia R, Ochoa-Zarzosa A, López-Meza JE (2020) Lipid-rich extract from Mexican avocado (Persea americana var. drymifolia) induces apoptosis and modulates the inflammatory response in Caco-2 human colon cancer cells. J Funct Foods 64:103658.HumanEndothelial;epithelial;mesothelial cellCell deathCancer
Reutzel 2020 Oxid Med Cell Longev2020Reutzel M, Grewal R, Dilberger B, Silaidos C, Joppe A, Eckert GP (2020) Cerebral mitochondrial function and cognitive performance during aging: A longitudinal study in NMRI mice. Oxid Med Cell Longev 2020:4060769.MouseNervous systemAging;senescence
Neurodegenerative
Chang 2020 J Biol Chem2020Chang L, Liu X, Diggle CP, Boyle JP, Hopkins PM, Shaw MA, Allen PD (2020) Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia. J Biol Chem 295:15226-35.MouseSkeletal muscle
Caspi 2020 J Am Heart Assoc2020Caspi T, Straw S, Cheng C, Garnham JO, Scragg JL, Smith J, Koshy AO, Levelt E, Sukumar P, Gierula J, Beech DJ, Kearney MT, Cubbon RM, Wheatcroft SB, Witte KK, Roberts LD, Bowen TS (2020) Unique transcriptome signature distinguishes patients with heart failure with myopathy. J Am Heart Assoc 9:e017091. https://doi.org/10.1161/JAHA.120.017091HumanHeart
Skeletal muscle
Cardiovascular
Myopathy
Hingst 2020 Mol Metab2020Hingst JR, Kjøbsted R, Birk JB, Jørgensen NO, Larsen MR, Kido K, Larsen JK, Kjeldsen SAS, Fentz J, Frøsig C, Holm S, Fritzen AM, Dohlmann TL, Larsen S, Foretz M, Viollet B, Schjerling P, Overby P, Halling JF, Pilegaard H, Hellsten Y, Wojtaszewski JFP (2020) Inducible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise. Mol Metab 40:101028.MouseSkeletal muscle
Juarez-Flores 2020 Antioxidants (Basel)2020Juarez-Flores DL, Ezquerra M, Gonzalez-Casacuberta I, Ormazabal A, Moren C, Tolosa E, Fucho R, Guitart-Mampel M, Casado M, Valldeoriola F, de la Torre-Lara J, Munoz E, Tobias E, Compta Y, Garcia-Garcia FJ, Garcia-Ruiz C, Fernandez-Checa JC, Marti MJ, Grau JM, Cardellach F, Artuch R, Fernandez-Santiago R, Garrabou G (2020) Disrupted mitochondrial and metabolic plasticity underlie comorbidity between age-related and degenerative disorders as Parkinson disease and type 2 diabetes mellitus. Antioxidants (Basel) 9:1063.HumanFibroblastDiabetes
Parkinson's
Vega 2020 Physiol Rep2020Vega RB, Brouwers B, Parsons SA, Stephens NA, Pino MF, Hodges A, Yi F, Yu G, Pratley RE, Smith SR, Sparks LM (2020) An improvement in skeletal muscle mitochondrial capacity with short-term aerobic training is associated with changes in Tribbles 1 expression. Physiol Rep 8:e14416.HumanSkeletal muscle
Nolfi-Donegan 2020 Redox Biol2020Nolfi-Donegan D, Braganza A, Shiva S (2020) Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement. Redox Biol 37:101674. https://doi.org/10.1016/j.redox.2020.101674
Garcia 2020 Mol Hum Reprod2020Garcia BM, Machado TS, Carvalho KF, Nolasco P, Nociti RP, Del Collado M, Capo Bianco MJD, Grejo MP, Neto JDA, Sugiyama FHC, Tostes K, Pandey AK, Gonçalves LM, Perecin F, Meirelles FV, Ferraz JBS, Vanzela EC, Boschero AC, Guimarães FEG, Abdulkader F, Laurindo FRM, Kowaltowski AJ, Chiaratti MR (2020) Mice born to females with oocyte-specific deletion of mitofusin 2 have increased weight gain and impaired glucose homeostasis. Mol Hum Reprod 26:938-52.MouseLiverDiabetes
Obesity
Kanellopoulos 2020 Cell2020Kanellopoulos AK, Mariano V, Spinazzi M, Woo YJ, McLean C, Pech U, Li KW, Armstrong JD, Giangrande A, Callaerts P, Smit AB, Abrahams BS, Fiala A, Achsel T, Bagni C (2020) Aralar sequesters GABA into hyperactive mitochondria, causing social behavior deficits. Cell 180:1178-97.DrosophilaNervous system
Other cell lines
Macasoi 2020 Oncol Rep2020Macașoi I, Pavel IZ, Moacă AE, Avram S, David LV, Coricovac D, Mioc A, Spandidos DA, Tsatsakis A, Șoica C, Dumitrașcu V, Dehelean C (2020) Mechanistic investigations of antitumor activity of a Rhodamine B‑oleanolic acid derivative bioconjugate. Oncol Rep 44:1169-83.HumanEndothelial;epithelial;mesothelial cellCancer
Cipullo 2020 Nucleic Acids Res2020Cipullo M, Pearce SF, Lopez Sanchez IG, Gopalakrishna S, Krüger A, Schober F, Busch JD, Li X, Wredenberg A, Atanassov I, Rorbach J (2020) Human GTPBP5 is involved in the late stage of mitoribosome large subunit assembly. Nucleic Acids Res 49:354-70.HumanHEK
Al-Azab 2020 FEBS J2020Al-Azab M, Qaed E, Ouyang X, Elkhider A, Walana W, Li H, Li W, Tang Y, Adlat S, Wei J, Wang B, Li X (2020) TL1A/TNFR2-mediated mitochondrial dysfunction of fibroblast-like synoviocytes increases inflammatory response in patients with rheumatoid arthritis via reactive oxygen species generation. FEBS J 287:3088-104.HumanOther cell linesOther
Hassan 2020 MitoFit Preprint Arch2020Hassan Hazirah, Gnaiger Erich, Zakaria Fazaine, Makpol Suzana, Abdul Karim Norwahidah (2020) Alterations in mitochondrial respiratory capacity and membrane potential: a link between mitochondrial dysregulation and autism. https://doi.org/10.26124/mitofit:200003HumanMitochondrial diseaseAutism
Guo 2020 Hum Gene Ther2020Guo Y, Zhang K, Gao X, Zhou Z, Liu Z, Yang K, Huang K, Yang Q, Long Q (2020) Sustained oligomycin sensitivity conferring protein expression in cardiomyocytes protects against cardiac hypertrophy induced by pressure-overload via improving mitochondrial function. Hum Gene Ther 31:1178-89.MouseHeart
Janowska 2020 Toxicol In Vitro2020Janowska JI, Piel S, Saliba N, Kim CD, Jang DH, Karlsson M, Kilbaugh TJ, Ehinger JK (2020) Mitochondrial respiratory chain Complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug carbamate toxicity and treatment. Toxicol In Vitro 65:104794.HumanPlatelet
Blood cells
Ayari 2020 Commun Biol2020Ayari Asma, Rosa-Calatrava Manuel, Lancel Steve, Barthelemy Johanna, Pizzorno Andres, Mayeuf-Louchart Alicia, Baron Morgane, Hot David, Deruyter Lucie, Soulard Daphnee, Julien Thomas, Faveeuw Christelle, Molendi-Coste Olivier, Dombrowicz David, Sedano Laura, Sencio Valentin, Le Goffic Ronan, Trottein Francois, Wolowczuk Isabelle (2020) Influenza infection rewires energy metabolism and induces browning features in adipose cells and tissues. Commun Biol 3:237.MouseFatInfectious
MiPNet20.14 AmplexRed H2O2-production2019-06-24
O2k-Protocols

O2k-FluoRespirometry: HRR and simultaneous determination of H2O2 production with Amplex UltraRed.

MouseHeart
MiPNet20.13 Safranin mt-membranepotential2019-06-24
O2k-Protocols

O2k-FluoRespirometry: HRR and simultaneous determination of mt-membrane potential with safranin or TMRM.

MouseNervous system
MiPNet18.05 Amplex-Mouse-heart2019-06-24
O2k-Protocols

O2k-Fluorometry: HRR and H2O2 production in mouse cardiac tissue homogenate.

MouseHeart
Grauso 2019 Sci Rep2019Grauso M, Lan A, Andriamihaja M, Bouillaud F, Blachier F (2019) Hyperosmolar environment and intestinal epithelial cells: impact on mitochondrial oxygen consumption, proliferation, and barrier function in vitro. Sci Rep 9:11360.HumanEndothelial;epithelial;mesothelial cell
Other cell lines
Cancer
Zhao 2019 Basic Res Cardiol2019Zhao J, Gao JL, Zhu JX, Zhu HB, Peng X, Jiang M, Fu Y, Xu J, Mao XH, Hu N, Ma MH, Dong DL (2019) The different response of cardiomyocytes and cardiac fibroblasts to mitochondria inhibition and the underlying role of STAT3. Basic Res Cardiol 114:12.RatHeart
Fibroblast
Ischemia-reperfusion
Gustafson 2019 PLoS One2019Gustafson MA, McCormick EM, Perera L, Longley MJ, Bai R, Kong J, Dulik M, Shen L, Goldstein AC, McCormack SE, Laskin BL, Leroy BP, Ortiz-Gonzalez XR, Ellington MG, Copeland WC, Falk MJ (2019) Mitochondrial single-stranded DNA binding protein novel de novo SSBP1 mutation in a child with single large-scale mtDNA deletion (SLSMD) clinically manifesting as Pearson, Kearns-Sayre, and Leigh syndromes. PLoS One 14:e0221829.HumanFibroblast
Lymphocyte
Other
Carteri 2019 Toxicol Lett2019Carteri RB, Kopzynski A, Menegassi LN, Rodolphi MS, Strogulski NR, Portela LV (2019) Anabolic-androgen steroids effects on bioenergetics responsiveness of synaptic and extrasynaptic mitochondria. Toxicol Lett 307:72-80.MouseNervous system
Desquiret-Dumas 2019 Biochim Biophys Acta Mol Basis Dis2019Desquiret-Dumas V, Leman G, Wetterwald C, Chupin S, Lebert A, Khiati S, Le Mao M, Geffroy G, Kane MS, Chevrollier A, Goudenege D, Gadras C, Tessier L, Barth M, Leruez S, Amati-Bonneau P, Henrion D, Bonneau D, Procaccio V, Reynier P, Lenaers G, Gueguen N (2019) Warburg-like effect is a hallmark of complex I assembly defects. Biochim Biophys Acta Mol Basis Dis 1865:2475-89.HumanFibroblastOther
Kirby 2019 Comp Biochem Physiol C Toxicol Pharmacol2019Kirby AR, Cox GK, Nelson D, Heuer RM, Stieglitz JD, Benetti DD, Grosell M, Crossley DA 2nd (2019) Acute crude oil exposure alters mitochondrial function and ADP affinity in cardiac muscle fibers of young adult Mahi-mahi (Coryphaena hippurus). Comp Biochem Physiol C Toxicol Pharmacol 218:88-95.FishesHeart
Rose 2019 Am J Physiol Endocrinol Metab2019Rose S, Carvalho E, Diaz EC, Cotter M, Bennuri SC, Azhar G, Frye RE, Adams SH, Børsheim E (2019) A comparative study of mitochondrial respiration in circulating blood cells and skeletal muscle fibers in women. Am J Physiol Endocrinol Metab 317:E503-E512. https://doi.org/10.1152/ajpendo.00084.2019HumanSkeletal muscle
Blood cells
Platelet