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	Year	Reference	Coupling	Pathway	Preparation	Organism	Tissue;cell
Christen 2018 Free Radic Biol Med	2018	Christen F, Desrosiers V, Dupont-Cyr BA, Vandenberg GW, Le François NR, Tardif JC, Dufresne F, Lamarre SG, Blier PU (2018) Thermal tolerance and thermal sensitivity of heart mitochondria: Mitochondrial integrity and ROS production. Free Radic Biol Med 116:11-8.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Fishes	Heart
Wu 2018 Adv Sci	2018	Wu S, Zhang A, Li S, Chatterjee S, Qi R, Segura-Ibarra V, Ferrari M, Gupte A, Blanco E, Hamilton DJ (2018) Polymer functionalization of isolated mitochondria for cellular transplantation and metabolic phenotype alteration. Adv Sci 1700530.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Liver
Sant'Anna-Silva 2018 Front Oncol	2018	Sant'Anna-Silva ACB, Santos GC, Campos SPC, Oliveira Gomes AM, Pérez-Valencia JA, Rumjanek FD (2018) Metabolic profile of oral squamous carcinoma cell lines relies on a higher demand of lipid metabolism in metastatic cells. Front Oncol 8:13.	LEAK ROUTINE ET	ROX	Intact cells	Human	Other cell lines Fibroblast
Dela 2018 Acta Physiol (Oxf)	2018	Dela F, Ingersen A, Andersen NB, Nielsen MB, Petersen HHH, Hansen CN, Larsen S, Wojtaszewski J, Helge JW (2018) Effects of one-legged high-intensity interval training on insulin-mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes. Acta Physiol (Oxf) 226:e13245.	OXPHOS LEAK	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Razak 2018 RUMeS	2018	Razak SHA, Hassan H, Hakimi NH, Rani NA, Ibrahim NF, Ngah WZW, Makpol S, Damanhuri MHA, Karim NA, Tan JK (2018) Isolation of mitochondria and measurement of oxygen consumption rate by high-resolution respirometry in rat hippocampus. RUMeS 6:11-18.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Rat	Nervous system
Fuhr 2018 EBioMedicine	2018	Fuhr L, El-Athman R, Scrima R, Cela O, Carbone A, Knoop H, Li Y, Hoffmann K, Laukkanen MO, Corcione F, Steuer R, Meyer TF, Mazzoccoli G, Capitanio N, Relógio A (2018) The circadian clock regulates metabolic phenotype rewiring via HKDC1 and modulates tumor progression and drug response in colorectal cancer. EBioMedicine 33:105-121.		ROX	Intact cells	Human	Other cell lines
Gao 2018 Free Radic Biol Med	2018	Gao JL, Zhao J, Zhu HB, Peng X, Zhu JX, Ma MH, Fu Y, Hu N, Tai Y, Xuan XC, Dong DL (2018) Characterizations of mitochondrial uncoupling induced by chemical mitochondrial uncouplers in cardiomyocytes. Free Radic Biol Med 124:288-98.	LEAK ROUTINE ET	ROX	Intact cells	Rat	Heart
Tai 2018 Acta Pharm Sin B	2018	Tai Y, Li L, Peng X, Zhu J, Mao X, Qin N, Ma M, Huo R, Bai Y, Dong D (2018) Mitochondrial uncoupler BAM15 inhibits artery constriction and potently activates AMPK in vascular smooth muscle cells. Acta Pharm Sin B 8:909-18.	LEAK ET	ROX	Intact cells	Mouse	Endothelial;epithelial;mesothelial cell
Ounpuu 2018 Biochem Cell Biol	2018	Ounpuu L, Truu L, Shevchuk I, Chekulayev V, Klepinin A, Koit A, Tepp K, Puurand M, Rebane-Klemm E, Käämbre T (2018) Comparative analysis of the bioenergetics of human adenocarcinoma Caco-2 cell line and postoperative tissue samples from colorectal cancer patients. Biochem Cell Biol [Epub ahead of print].	LEAK OXPHOS	N S CIV ROX	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell Other cell lines
Rundle 2018 Environ Sci Technol	2018	Rundle K, Sharaf M, Stevens D, Kamunde C, Van Den Heuvel MR (2018) Oil sands-derived naphthenic acids are oxidative uncouplers and impair electron transport in isolated mitochondria. Environ Sci Technol 52:10803-11.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Fishes	Liver
Qu 2018 FASEB J	2018	Qu C, Zhang S, Wang W, Li M, Wang Y, van der Heijde-Mulder M, Shokrollahi E, Hakim MS, Raat NJH, Peppelenbosch MP, Pan Q (2018) Mitochondrial electron transport chain complex III sustains hepatitis E virus replication and represents an antiviral target. FASEB J 33:1008-19.	LEAK ROUTINE	CIV ROX	Intact cells	Human	Liver
Khamoui 2018 J Dev Orig Health Dis	2018	Khamoui AV, Desai M, Ross MG, Rossiter HB (2018) Sex-specific effects of maternal and postweaning high-fat diet on skeletal muscle mitochondrial respiration. J Dev Orig Health Dis 16:1-8.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Uribe-Alvarez 2018 Microbiologyopen	2018	Uribe-Alvarez C, Chiquete-Félix N, Morales-García L, Bohórquez-Hernández A, Delgado-Buenrostro NL, Vaca L, Peña A, Uribe-Carvajal S (2018) Wolbachia pipientis grows in Saccharomyces cerevisiae evoking early death of the host and deregulation of mitochondrial metabolism. Microbiologyopen 8:e00675.	OXPHOS ET	CIV ROX N NS	Isolated mitochondria	Saccharomyces cerevisiae
Manakov 2018 J Physiol Biochem	2018	Manakov D, Kolar D, Zurmanova J, Pravenec M, Novotny J (2018) Changes in the activity of some metabolic enzymes in the heart of SHR rat incurred by transgenic expression of CD36. J Physiol Biochem 74:479-89.	LEAK OXPHOS ET	F N S NS ROX	Isolated mitochondria	Rat	Heart
Karlsson 2018 J Neurotrauma	2018	Karlsson M, Pukenas B, Chawla S, Ehinger JK, Plyler R, Stolow M, Gabello M, Hugerth M, Elmér E, Hansson MJ, Margulies S, Kilbaugh T (2018) Neuroprotective effects of cyclosporine in a porcine pre-clinical trial of focal traumatic brain injury. J Neurotrauma 36:14-24.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Pig	Nervous system
Cunatova 2018 Thesis	2018	Čunátová K (2018) The role of tissue specific isoforms of subunit 4 in assembly and function of cytochrome c oxidase. PhD Thesis p107.	LEAK ROUTINE ET	CIV ROX	Intact cells	Human	HEK
Deschaseaux 2018 US Patent	2018	Deschaseaux F, Guilloton F, Muller S, Sensebe L, Casteilla L, Carriere-Pazat A (2018) Method for obtaining human brown/beige adipocytes . US Patent US20180216070A1.	LEAK ROUTINE ET	ROX	Intact cells	Human	Fat
Kappler 2018 Thesis	2018	Kappler L (2018) Method development for valid high‐resolution profiling of mitochondria and Omics investigation of mitochondrial adaptions to excess energy intake and physical exercise. Dissertation p181.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized cells Homogenate Isolated mitochondria	Human Mouse	Skeletal muscle Liver Other cell lines
Furlanetto 2018 Physiol Plant	2018	Furlanetto ALDM, Cadena SMSC, Martinez GR, Ferrando B, Stevnsner T, Møller IM (2018) Short-term high temperature treatment reduces viability and inhibits respiration and DNA repair enzymes in Araucaria angustifolia cells. Physiol Plant 166:513-24.	ET ROUTINE	N CIV ROX	Intact cells	Plants
Burney 2018 Thesis	2018	Burney E (2018) Characterization of mitochondrial metabolism in L6 rat myoblasts. Bachelor's Thesis p50.	LEAK ROUTINE OXPHOS ET	F N S Gp NS Other combinations ROX	Permeabilized cells Intact cells	Rat	Other cell lines
Liu 2018 J Periodontol	2018	Liu J, Zeng J, Wang X, Zheng M, Luan Q (2018) P53 mediates lipopolysaccharide-induced inflammation in human gingival fibroblasts. J Periodontol 89:1142-51.	LEAK ET	ROX	Intact cells	Human	Fibroblast
Piel 2018 Intensive Care Med Exp	2018	Piel S, Ehinger JK, Chamkha I, Frostner EÅ, Sjövall F, Elmér E, Hansson MJ (2018) Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production. Intensive Care Med Exp 6:22.	LEAK	S ROX	Intact cells	Human	Platelet Blood cells
Audia 2018 Basic Res Cardiol	2018	Audia JP, Yang XM, Crockett ES, Housley N, Haq EU, O'Donnell K, Cohen MV, Downey JM, Alvarez DF (2018) Caspase‑1 inhibition by VX‑765 administered at reperfusion in P2Y12 receptor antagonist‑treated rats provides long‑term reduction in myocardial infarct size and preservation of ventricular function. Basic Res Cardiol 113:32.	OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Rat	Heart
Burtscher 2018 Front Mol Neurosci	2018	Burtscher J, Bean C, Zangrandi L, Kmiec I, Agostinho A, Scorrano L, Gnaiger E, Schwarzer C (2018) Proenkephalin derived peptides are involved in the modulation of mitochondrial respiratory control during epileptogenesis. Front Mol Neurosci doi:10.3389/fnmol.2018.00351.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Song 2018 J Cell Physiol	2018	Song Y, Gao L, Tang Z, Li H, Sun B, Chu P, Qaed E, Ma X, Peng J, Wang S, Hu M, Tang Z (2018) Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo. J Cell Physiol 234:777-88.	LEAK ET	ROX	Intact cells	Human	Islet cell;pancreas;thymus
Lee 2018 Reprod Sci	2018	Lee HC, Lin SC, Wu MH, Tsai SJ (2018) Induction of pyruvate dehydrogenase kinase 1 by hypoxia alters cellular metabolism and inhibits apoptosis in endometriotic stromal cells. Reprod Sci 26:734-44.	LEAK ROUTINE	ROX	Intact cells	Human	Genital
Dogan 2018 Cell Metab	2018	Dogan SA, Cerutti R, Benincá C, Brea-Calvo G, Jacobs HT, Zeviani M, Szibor M, Viscomi C (2018) Perturbed redox signaling exacerbates a mitochondrial myopathy. Cell Metab 28:764-77.	LEAK OXPHOS	N S CIV ROX	Isolated mitochondria	Mouse	Skeletal muscle
Brouwers 2018 Front Physiol	2018	Brouwers B, Stephens NA, Costford SR, Hopf ME, Ayala JE, Yi F, Xie H, Li JL, Gardell SJ, Sparks LM, Smith SR (2018) Elevated nicotinamide phosphoribosyl transferase in skeletal muscle augments exercise performance and mitochondrial respiratory capacity following exercise training. Front Physiol 9:704.	OXPHOS ET	F N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Rajasekaran 2018 FASEB J	2018	Rajasekaran R, Felser A, Nuoffer JM, Dufour JF, St-Pierre MV (2018) The histidine triad nucleotide-binding protein 2 (HINT-2) positively regulates hepatocellular energy metabolism. FASEB J 32:5143-61.	LEAK OXPHOS ET	N S CIV ROX	Isolated mitochondria	Mouse	Liver
Mayer 2018 Endocrinology	2018	Mayer AL, Zhang Y, Feng EH, Higgins CB, Adenekan O, Pietka TA, Beatty WL, DeBosch BJ (2018) Enhanced hepatic PPARα activity links GLUT8 deficiency to augmented peripheral fasting responses in male mice. Endocrinology 159:2110-26.	OXPHOS ET	N S NS ROX	Permeabilized tissue Homogenate	Mouse	Skeletal muscle Liver
Ost 2018 Curr Opin Clin Nutr Metab Care	2018	Ost M, Doerrier C, Gama-Perez P, Moreno-Gomez S (2018) Analysis of mitochondrial respiratory function in tissue biopsies and blood cells. Curr Opin Clin Nutr Metab Care 21:336-42.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Permeabilized tissue Isolated mitochondria Intact cells		Blood cells Platelet Skeletal muscle Liver Fat
Stepanova 2018 J Cereb Blood Flow Metab	2018	Stepanova A, Konrad C, Guerrero-Castillo S, Manfredi G, Vannucci S, Arnold S, Galkin A (2018) Deactivation of mitochondrial complex I after hypoxia-ischemia in the immature brain. J Cereb Blood Flow Metab 39:1790-802.	OXPHOS ET LEAK	N S ROX	Isolated mitochondria	Rat	Nervous system
Gatterer 2018 J Sports Sci Med	2018	Gatterer H, Menz V, Salazar-Martinez E, Sumbalova Z, Garcia-Souza LF, Cizmarova B, Gnaiger E, Burtscher M (2018) Exercise performance, muscle oxygen extraction and blood cell mitochondrial respiration after repeated-sprint and sprint interval training in hypoxia: a pilot study. J Sports Sci Med 17:339-347.	ROUTINE ET	ROX	Intact cells	Human	Blood cells Platelet
Tarpey 2018 Skelet Muscle	2018	Tarpey MD, Amorese AJ, Balestrieri NP, Ryan TE, Schmidt CA, McClung JM, Spangenburg EE (2018) Characterization and utilization of the flexor digitorum brevis for assessing skeletal muscle function. Skelet Muscle 8:14.	OXPHOS	N S CIV NS ROX		Mouse	Skeletal muscle
Komlodi 2018 Methods Mol Biol	2018	Komlodi T, Sobotka O, Krumschnabel G, Bezuidenhout N, Hiller E, Doerrier C, Gnaiger E (2018) Comparison of mitochondrial incubation media for measurement of respiration and hydrogen peroxide production. Methods Mol Biol 1782:137-55.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized cells Permeabilized tissue	Human Mouse	Skeletal muscle HEK
JanssenDuijghuijsen 2018 Thesis	2018	JanssenDuijghuijsen LM (2018) Good, Bad, or Risky? Intestinal permeability to protein: Human and in vitro studies. Doctoral Thesis p154.	LEAK ROUTINE ET	ROX	Intact cells	Human	Endothelial;epithelial;mesothelial cell
Hecker 2018 Biochim Biophys Acta	2018	Hecker M, Sommer N, Foch S, Hecker A, Hackstein H, Witzenrath M, Weissmann N, Seeger W, Mayer K (2018) Resolvin E1 and its precursor 18R-HEPE restore mitochondrial function in inflammation. Biochim Biophys Acta 1863:1016-28.	LEAK ROUTINE ET	ROX	Intact cells	Human	Blood cells
Kong 2018 Proteomics	2018	Kong D, Tian X, Li Y*, Zhang S, Cheng Y, Huo L, Ma H, Yang Z, Ren L, Zhang M, Zhang W (2018) Revealing the inhibitory effect of ginseng on mitochondrial respiration through synaptosomal proteomics. Proteomics 18:e1700354.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Homogenate	Rat	Nervous system
Martinez 2018 Arch Biochem Biophys	2018	Martínez JH, Fuentes F, Vanasco V, Alvarez S, Alaimo A, Cassina A, Coluccio Leskow F, Velazquez F (2018) Alpha-synuclein mitochondrial interaction leads to irreversible translocation and complex I impairment. Arch Biochem Biophys 651:1-12.	LEAK OXPHOS ET	N S ROX	Isolated mitochondria	Rat	Nervous system
Stanford 2018 Cell Metab	2018	Stanford KI, Lynes MD, Takahashi H, Baer LA, Arts PJ, May FJ, Lehnig AC, Middelbeek RJW, Richard JJ, So K, Chen EY, Gao F, Narain NR, Distefano G, Shettigar VK, Hirshman MF, Ziolo MT, Kiebish MA, Tseng YH, Coen PM, Goodyear LJ (2018) 12,13-diHOME: an exercise-induced lipokine that increases skeletal muscle fatty acid uptake. Cell Metab 27:1111-20.	LEAK OXPHOS ET	F ROX	Permeabilized tissue	Human Mouse	Skeletal muscle
Tillmans 2018 Thesis	2018	Tillmans F (2018) Effect of normobaric hypoxia on leukemic vell lines in vitro. Dissertation p92.	LEAK ROUTINE ET	N S NS ROX	Intact cells Permeabilized cells	Human	Other cell lines Lymphocyte
Salin 2018 Funct Ecol	2018	Salin K, Villasevil EM, Anderson GJ, Auer SK, Selman C, Hartley RC, Mullen W, Chinopoulos C, Metcalfe NB (2018) Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost. Funct Ecol DOI: 10.1111/1365-2435.13125.	LEAK OXPHOS	CIV NS ROX	Homogenate	Fishes	Liver
Yang 2018 Cell Death Dis	2018	Yang F, Wu R, Jiang Z, Chen J, Nan J, Su S, Zhang N, Wang C, Zhao J, Ni C, Wang Y, Hu W, Zeng Z, Zhu K, Liu X, Hu X, Zhu W, Yu H, Huang J, Wang J (2018) Leptin increases mitochondrial OPA1 via GSK3-mediated OMA1 ubiquitination to enhance therapeutic effects of mesenchymal stem cell transplantation. Cell Death Dis 9:556.		N S CIV NS ROX	Intact cells	Mouse
Robb 2018 J Biol Chem	2018	Robb EL, Hall AR, Prime TA, Eaton S, Szibor M, Viscomi C, James AM, Murphy MP (2018) Control of mitochondrial superoxide production by reverse electron transport at complex I. J Biol Chem 293:9869-79. https://doi.org/10.1074/jbc.RA118.003647	ET	N S ROX	Isolated mitochondria	Rat	Heart
Kamunde 2018 Free Radic Biol Med	2018	Kamunde C, Sharaf M, MacDonald N (2018) H₂O₂ metabolism in liver and heart mitochondria: Low emitting-high scavenging and high emitting-low scavenging systems. Free Radic Biol Med 124:135-48.	LEAK	N ROX	Isolated mitochondria	Fishes	Heart Liver
Jang 2018 Shock	2018	Jang DH, Orloski CJ, Owiredu S, Shofer FS, Greenwood JC, Eckmann DM (2018) Alterations in mitochondrial function in blood cells obtained from patients with sepsis presenting to an emergency department. Shock 51:580-84.	LEAK ROUTINE ET	ROX		Human	Blood cells
Logan 2018 Thesis	2018	Logan C (2018) Nitrate and nitrite differentially affect respiration in zebrafish during exercise. Honors Baccalaureate of Science in Nutrition p44.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Zebrafish	Skeletal muscle
Durand 2018 Blood Purif	2018	Durand PY, Nicco C, Serteyn D, Attaf D, Edeas M (2018) Microbiota quality and mitochondrial activity link with occurrence of muscle cramps in hemodialysis patients using citrate dialysate: a pilot study. Blood Purif 46:301-8.	LEAK ROUTINE OXPHOS ET	S ROX	Intact cells	Human	Platelet Blood cells
Boeck 2018 Sci Rep	2018	Boeck C, Salinas-Manrique J, Calzia E, Radermacher P, von Arnim CAF, Dietrich DE, Kolassa IT, Karabatsiakis A (2018) Targeting the association between telomere length and immunocellular bioenergetics in female patients with Major Depressive Disorder. Sci Rep 8:9419.	LEAK ROUTINE ET	N ROX	Intact cells	Human	Blood cells
Kriel 2018 Sci Rep	2018	Kriel J, Mueller-Nedebock K, Maarman G, Mbizana S, Ojuka E, Klumperman B, Loos B (2018) Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics. Sci Rep 8:10348.	LEAK OXPHOS ET ROUTINE	N ROX	Permeabilized cells	Human	Nervous system Other cell lines
Silaidos 2018 Biol Sex Differ	2018	Silaidos C, Pilatus U, Grewal R, Matura S, Lienerth B, Pantel J, Eckert GP (2018) Sex-associated differences in mitochondrial function in human peripheral blood mononuclear cells (PBMCs) and brain. Biol Sex Differ 9:34.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Nervous system Blood cells
Sims 2018 JCI Insight	2018	Sims CA, Guan Y, Mukherjee S, Singh K, Botolin P, Davila A Jr, Baur JA (2018) Nicotinamide mononucleotide preserves mitochondrial function and increases survival in hemorrhagic shock. JCI Insight 3:120182.	OXPHOS	N S CIV ROX	Permeabilized cells Isolated mitochondria	Rat	Liver Kidney
Weber 2018 Int J Mol Sci	2018	Weber A, Klocker H, Oberacher H, Gnaiger E, Neuwirt H, Sampson N, Eder IE (2018) Succinate accumulation is associated with a shift of mitochondrial respiratory control and HIF-1α upregulation in PTEN negative prostate cancer cells. Int J Mol Sci 19:2129.	ROUTINE OXPHOS ET	F N S NS Other combinations ROX	Intact cells Permeabilized cells	Human	Genital
Pileggi 2018 Free Radic Biol Med	2018	Pileggi CA, Hedges CP, D'Souza RF, Durainayagam BR, Markworth JF, Hickey AJR, Mitchell CJ, Cameron-Smith D (2018) Exercise recovery increases skeletal muscle H₂O₂ emission and mitochondrial respiratory capacity following two-weeks of limb immobilization. Free Radic Biol Med 124:241-8.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Salin 2018 Integr Comp Biol	2018	Salin K, Villasevil EM, Anderson GJ, Selman C, Chinopoulos C, Metcalfe NB (2018) The RCR and ATP/O indices can give contradictory messages about mitochondrial efficiency. Integr Comp Biol 58:486-94.	LEAK OXPHOS	N S NS ROX	Homogenate	Fishes	Liver
Seite 2018 Sci Rep	2018	Seite S, Mourier A, Camougrand N, Salin B, Figueiredo-Silva AC, Fontagne-Dicharry S, Panserat S, Seiliez I (2018) Dietary methionine deficiency affects oxidative status, mitochondrial integrity and mitophagy in the liver of rainbow trout (Oncorhynchus mykiss). Sci Rep 8:10151.		N S CIV NS ROX	Homogenate	Fishes	Liver
Rodrigues 2018 Sci Rep	2018	Rodrigues APC, Camargo AF, Andjelkovic A, Jacobs HT, Oliveira MT (2018) Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase. Sci Rep 8:10882.	OXPHOS	N CIV ROX	Homogenate Oxidase;biochemical oxidation	Drosophila
Barca 2018 Hum Mol Genet	2018	Barca E, Ganetzky RD, Potluri P, Juanola-Falgarona M, Gai X, Li D, Jalas C, Hirsch Y, Emmanuele V, Tadesse S, Ziosi M, Akman HO, Chung WK, Tanji K, McCormick E, Place E, Consugar M, Pierce EA, Hakonarson H, Wallace DC, Hirano M, Falk MJ (2018) USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis. Hum Mol Genet 27:3305-12.	LEAK ROUTINE OXPHOS ET	F N S DQ NS ROX	Permeabilized cells Intact cells	Human	Fibroblast
Hafen 2018 J Appl Physiol (1985)	2018	Hafen PS, Preece CN, Sorensen JR, Hancock CR, Hyldahl RD (2018) Repeated exposure to heat stress induces mitochondrial adaptation in human skeletal muscle. J Appl Physiol (1985) 125:1447-55.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Chou 2018 Int J Cardiol	2018	Chou CH, Fu TC, Tsai HH, Hsu CC, Wang CH, Wang JS (2018) High-intensity interval training enhances mitochondrial bioenergetics of platelets in patients with heart failure. Int J Cardiol 274:214-20.	LEAK ROUTINE OXPHOS ET	F N S NS ROX	Intact cells Permeabilized cells	Human	Platelet Blood cells
Van der Pluijm 2018 Cardiovasc Res	2018	van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane E, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz H, Kanaar R, Essers J (2018) Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation. Cardiovasc Res 114:1776-93.	OXPHOS	N S NS ROX	Homogenate	Mouse	Skeletal muscle
Paech 2018a Toxicology	2018	Paech F, Mingard C, Grünig D, Abegg VF, Bouitbir J, Krähenbühl S (2018) Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells. Toxicology 395:34-44.	LEAK OXPHOS ET	N S DQ CIV ROX	Permeabilized cells Isolated mitochondria	Human Mouse	Liver Other cell lines
Paech 2018b Toxicology	2018	Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, Krähenbühl S (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology 409:13-23.	LEAK OXPHOS ET	N S DQ CIV ROX NS	Isolated mitochondria	Mouse	Liver
Casal 2018 J Anim Sci	2018	Casal A, Garcia-Roche M, Navajas EA, Cassina A, Carriquiry M (2018) Hepatic mitochondrial function in Hereford steers with divergent residual feed intake phenotypes. J Anim Sci 96:4431-43.	LEAK OXPHOS ET	N S ROX	Intact cells	Bovines	Liver
Klepinin 2018 J Bioenerg Biomembr	2018	Klepinin A, Ounpuu L, Mado K, Truu L, Chekulayev V, Puurand M, Shevchuk I, Tepp K, Planken A, Kaambre T (2018) The complexity of mitochondrial outer membrane permeability and VDAC regulation by associated proteins. J Bioenerg Biomembr 50:339-54.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells	Mouse	Heart Neuroblastoma
Lu 2018 Cell Rep	2018	Lu Z, Cui Y, Wei X, Gao P, Zhang H, Wei X, Li Q, Sun F, Yan Z, Zheng H, Yang G, Liu D, Zhu Z (2018) Deficiency of PKD2L1 (TRPP3) exacerbates pathological cardiac hypertrophy by augmenting NCX1-mediated mitochondrial calcium overload. Cell Rep 24:1639-52.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Mouse	Heart
Lu 2018 Cell Discov	2018	Lu Z, Wei X, Sun F, Zhang H, Gao P, Pu Y, Wang A, Chen J, Tong W, Li Q, Zhou X, Yan Z, Zheng H, Yang G, Huang Y, Liu D, Zhu Z (2018) Non-insulin determinant pathways maintain glucose homeostasis upon metabolic surgery. Cell Discov 4:58.	OXPHOS ET	F N ROX	Isolated mitochondria	Rat	Skeletal muscle Liver
Monaco 2018b Diabetologia	2018	Monaco CMF, Hughes MC, Ramos SV, Varah NE, Lamberz C, Rahman FA, McGlory C, Tarnopolsky MA, Krause MP, Laham R, Hawke TJ, Perry CGR (2018) Altered mitochondrial bioenergetics and ultrastructure in the skeletal muscle of young adults with type 1 diabetes. Diabetologia 61:1411-23.	OXPHOS	N S Gp NS ROX	Permeabilized tissue	Human	Skeletal muscle
Ryan 2018 JCI Insight	2018	Ryan TE, Yamaguchi DJ, Schmidt CA, Zeczycki TN, Shaikh SR, Brophy P, Green TD, Tarpey MD, Karnekar R, Goldberg EJ, Sparagna GC, Torres MJ, Annex BH, Neufer PD, Spangenburg EE, McClung JM (2018) Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants. JCI Insight 3:123235.	OXPHOS LEAK	N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Bombaca 2018 Free Radic Biol Med	2018	Bombaça ACS, Viana PG, Santos ACC, Silva TL, Rodrigues ABM, Guimarães ACR, Goulart MOF, Da Silva Júnior EN, Menna-Barreto RFS (2018) Mitochondrial disfunction and ROS production are essential for anti-Trypanosoma cruzi activity of β-lapachone-derived naphthoimidazoles. Free Radic Biol Med 130:408-18.	ROUTINE	ROX	Intact organism	Protists
Aparicio-Trejo 2018 Free Radic Biol Med	2018	Aparicio-Trejo OE, Reyes-Fermín LM, Briones-Herrera A, Tapia E, León-Contreras JC, Hernández-Pando R, Sánchez-Lozada LG, Pedraza-Chaverri J (2018) Protective effects of N-acetyl-cysteine in mitochondria bioenergetics, oxidative stress, dynamics and S-glutathionylation alterations in acute kidney damage induced by folic acid. Free Radic Biol Med 130:379-96.	LEAK OXPHOS	N S NS ROX	Intact cells Isolated mitochondria	Rat	Kidney
Holland 2018 Cell Death Dis	2018	Holland OJ, Cuffe JSM, Dekker Nitert M, Callaway L, Kwan Cheung KA, Radenkovic F, Perkins AV (2018) Placental mitochondrial adaptations in preeclampsia associated with progression to term delivery. Cell Death Dis 9:1150.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Human	Genital
Falcao-Tebas 2018 J Physiol	2018	Falcão-Tebas F, Kuang J, Arceri C, Kerris JP, Andrikopoulos S, Marin EC, McConell GK (2018) Four weeks of exercise early in life reprograms adult skeletal muscle insulin resistance caused by paternal high fat diet. J Physiol 597:121-36.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Rat	Skeletal muscle
Scheiber 2018 J Cardiovasc Transl Res	2018	Scheiber D, Zweck E, Jelenik T, Horn P, Albermann S, Masyuk M, Boeken U, Saeed D, Kelm M Roden M, Szendroedi J, Westenfeld R (2018) Reduced myocardial mitochondrial ROS production in mechanically unloaded hearts. J Cardiovasc Transl Res 12:107-15.	LEAK OXPHOS ET	F N NS ROX	Permeabilized tissue	Human	Heart
Champigny 2018 Mar Drugs	2018	Champigny CM, Cormier RPJ, Simard CJ, St-Coeur PD, Fortin S, Pichaud N (2018) Omega-3 monoacylglyceride effects on longevity, mitochondrial metabolism and oxidative stress: insights from Drosophila melanogaster. Mar Drugs 16:E453.	LEAK OXPHOS ET	N S NS ROX Gp	Permeabilized tissue	Drosophila
Lobo-Jarne 2018 Cell Rep	2018	Lobo-Jarne T, Nývltová E, Pérez-Pérez R, Timón-Gómez A, Molinié T, Choi A, Mourier A, Fontanesi F, Ugalde C, Barrientos A (2018) Human COX7A2L regulates complex III biogenesis and promotes supercomplex organization remodeling without affecting mitochondrial bioenergetics. Cell Rep 25:1786-99.	LEAK OXPHOS ET	N S NS ROX Gp	Permeabilized cells	Human	HEK Other cell lines
Quispe 2018 Redox Biol	2018	Quispe RL, Jaramillo ML, Galant LS, Engel D, Dafre AL, Teixeira da Rocha JB, Radi R, Farina M, de Bem AF (2018) Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction: Involvement of the glutathione-dependent antioxidant system. Redox Biol 20:118-29.	LEAK ET ROUTINE	ROX	Intact cells	Mouse	Nervous system Other cell lines
Wilmanns 2018 Mol Metab	2018	Wilmanns JC, Pandey R, Hon O, Chandran A, Schilling JM, Forte E, Wu Q, Cagnone G, Bais P, Philip V, Coleman D, Kocalis H, Archer SK, Pearson JT, Ramialison M, Heineke J, Patel HH, Rosenthal NA, Furtado MB, Costa MW (2018) Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease. Mol Metab 20:102-14.	LEAK OXPHOS ET	F N NS ROX	Permeabilized tissue	Mouse	Heart
Bialas 2018 Int J Chron Obstruct Pulmon Dis	2018	Białas AJ, Siewiera K, Watała C, Rybicka A, Grobelski B, Kośmider L, Kurek J, Miłkowska-Dymanowska J, Piotrowski WJ, Górski P (2018) Mitochondrial functioning abnormalities observed in blood platelets of chronic smoke-exposed guinea pigs – a pilot study. Int J Chron Obstruct Pulmon Dis 13:3707—17 .	LEAK ROUTINE ET	ROX	Intact cells	Guinea pig	Platelet
Friederich 2018 Nat Commun	2018	Friederich MW, Timal S, Powell CA, Dallabona C, Kurolap A, Palacios-Zambrano S, Bratkovic D, Derks TGJ, Bick D, Bouman K, Chatfield KC, Damouny-Naoum N, Dishop MK, Falik-Zaccai TC, Fares F, Fedida A, Ferrero I, Gallagher RC, Garesse R, Gilberti M, González C, Gowan K, Habib C, Halligan RK, Kalfon L, Knight K, Lefeber D, Mamblona L, Mandel H, Mory A, Ottoson J, Paperna T, Pruijn GJM, Rebelo-Guiomar PF, Saada A, Sainz B Jr, Salvemini H, Schoots MH, Smeitink JA, Szukszto MJ, Ter Horst HJ, van den Brandt F, van Spronsen FJ, Veltman JA, Wartchow E, Wintjes LT, Zohar Y, Fernández-Moreno MA, Baris HN, Donnini C, Minczuk M, Rodenburg RJ, Van Hove JLK (2018) Pathogenic variants in glutamyl-tRNA^Gln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder. Nat Commun 9:4065.	ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human Fungi	Fibroblast
Mendes 2018 Mol Neurobiol	2018	Mendes Lima JP, Rayêe D, Silva-Rodrigues T, Ribeiro Paes Pereira P, Mendonca APM, Rodrigues-Ferreira C, Szczupak D, Fonseca A, Oliveira MF, Souza Lima FR, Lent R, Galina A, Uziel D (2018) Perinatal asphyxia and brain development: mitochondrial damage without anatomical or cellular losses. Mol Neurobiol doi.org/10.1007/s12035-018-1019-7.	LEAK ROUTINE ET	N NS ROX	Intact cells	Rat	Nervous system
Konopka 2018 Aging Cell	2018	Konopka AR, Laurin JL, Schoenberg HM, Reid JJ, Castor WM, Wolff CA, Musci RV, Safairad OD, Linden MA, Biela LM, Bailey SM, Hamilton KL, Miller BF (2018) Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults. Aging Cell 18:e12880.	OXPHOS ET LEAK	F N NS S ROX	Permeabilized tissue	Human	Skeletal muscle
Becker 2018 EMBO Rep	2018	Becker C, Kukat A, Szczepanowska K, Hermans S, Senft K, Brandscheid CP, Maiti P, Trifunovic A (2018) CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis. EMBO Rep 19. pii: e45126.	LEAK OXPHOS ET	F N S NS ROX	Isolated mitochondria	Mouse	Liver Fat
Pamenter 2018 PLoS One	2018	Pamenter ME, Lau GY, Richards JG (2018) Effects of cold on murine brain mitochondrial function. PLoS One 13:e0208453.	LEAK OXPHOS ET	N S CIV ROX	Permeabilized tissue	Mouse	Nervous system
Niu 2018 Cancer Metab	2018	Niu X, Chen YJ, Crawford PA, Patti GJ (2018) Transport-exclusion pharmacology to localize lactate dehydrogenase activity within cells. Cancer Metab 6:19.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Human	HeLa
Thompson 2018 EMBO Mol Med	2018	Thompson K, Mai N, Oláhová M, Scialó F, Formosa LE, Stroud DA, Garrett M, Lax NZ, Robertson FM, Jou C, Nascimento A, Ortez C, Jimenez-Mallebrera C, Hardy SA, He L, Brown GK, Marttinen P, McFarland R, Sanz A, Battersby BJ, Bonnen PE, Ryan MT, Chrzanowska-Lightowlers ZM, Lightowlers RN, Taylor RW (2018) OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect. EMBO Mol Med 10:e9060.	LEAK OXPHOS	N CIV ROX Gp Other combinations	Homogenate	Drosophila
Hancock 2018 Elife	2018	Hancock M, Hafstad AD, Nabeebaccus AA, Catibog N, Logan A, Smyrnias I, Hansen SS, Lanner J, Schröder K, Murphy MP, Shah AM, Zhang M (2018) Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise. Elife 7:e41044.	LEAK OXPHOS ET	F N S NS ROX	Isolated mitochondria	Mouse	Heart
Campbell 2018 Free Radic Biol Med	2018	Campbell MD, Duan J, Samuelson AT, Gaffrey MJ, Wang L, Bammler TK, Moore RJ, White CC, Kavanagh TJ, Voss JG, Szeto HH, Rabinovitch PS, Qian WJ, Marcinek DJ (2018) Improving mitochondrial function with SS-31 reverses age-related redox stress and improves exercise tolerance in aged mice. Free Radic Biol Med 134:268-81.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Reutzel 2018 Oxid Med Cell Longev	2018	Reutzel M, Grewal R, Silaidos C, Zotzel J, Marx S, Tretzel J, Eckert GP (2018) Effects of long-term treatment with a blend of highly purified olive secoiridoids on cognition and brain ATP levels in aged NMRI mice. Oxid Med Cell Longev 2018:4070935.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Martins 2018 Oxid Med Cell Longev	2018	Martins IK, de Carvalho NR, Macedo GE, Rodrigues NR, Ziech CC, Vinadé L, Filho VMB, Menezes IA, Franco J, Posser T (2018) Anacardium microcarpum promotes neuroprotection dependently of AKT and ERK phosphorylation but does not prevent mitochondrial damage by 6-OHDA. Oxid Med Cell Longev 2018:2131895.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Chicken	Nervous system
Goncalves 2018 Neurotoxicology	2018	Gonçalves DF, Courtes AA, Hartmann DD, da Rosa PC, Oliveira DM, Soares FAA, Dalla Corte CL (2018) 6-Hydroxydopamine induces different mitochondrial bioenergetics response in brain regions of rat. Neurotoxicology 70:1-11.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Rat	Nervous system
Hedges 2018 FASEB J	2018	Hedges CP, Bishop DJ, Hickey AJR (2018) Voluntary wheel running prevents the acidosis-induced decrease in skeletal muscle mitochondrial reactive oxygen species emission. FASEB J 33:4996-5004.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Rat	Skeletal muscle
Hedges 2018 J Appl Physiol (1985)	2018	Hedges CP, Woodhead JST, Wang HW, Mitchell CJ, Cameron-Smith D, Hickey AJR, Merry TL (2018) Peripheral blood mononuclear cells do not reflect skeletal muscle mitochondrial function or adaptation to high-intensity interval training in healthy young men. J Appl Physiol (1985) 126:454-61.	LEAK OXPHOS ET	N CIV NS ROX	Permeabilized tissue Intact cells	Human	Skeletal muscle Blood cells
Brunetta 2018 Exp Physiol	2018	Brunetta HS, de Paula GC, de Oliveira J, Martins EL, Dos Santos GJ, Filho AG, Rafacho A, de Bem AF, Nunes EA (2018) Decrement in resting and insulin-stimulated soleus muscle mitochondrial respiration is an early event in diet-induced obesity in mice. Exp Physiol 104:306-21.	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Eimre 2018 Oxid Med Cell Longev	2018	Eimre M, Paju K, Peet N, Kadaja L, Tarrend M, Kasvandik S, Seppet J, Ivask M, Orlova E, Kõks S (2018) Increased mitochondrial protein levels and bioenergetics in the musculus rectus femoris of Wfs1-deficient mice. Oxid Med Cell Longev 2018:3175313.	OXPHOS LEAK	N S CIV ROX	Permeabilized tissue	Mouse	Skeletal muscle
Groennebaek 2018 Front Physiol	2018	Groennebaek T, Jespersen NR, Jakobsgaard JE, Sieljacks P, Wang J, Rindom E, Musci RV, Bøtker HE, Hamilton KL, Miller BF, de Paoli FV, Vissing K (2018) Skeletal muscle mitochondrial protein synthesis and respiration increase with low-load blood flow restricted as well as high-load resistance training. Front Physiol 9:1796.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
MacMillan-Crow 2018 Intern Med Rev (Wash D C)	2018	MacMillan-Crow LA, Mayeux PR (2018) Female mice exhibit less renal mitochondrial injury but greater mortality using a comorbid model of experimental sepsis. Intern Med Rev (Wash D C) 4.	OXPHOS LEAK	N S ROX	Permeabilized tissue	Mouse	Kidney
Dejos 2018 Sci Rep	2018	Dejos C, Kuny S, Han WH, Capel H, Lemieux H, Sauvé Y (2018) Photoreceptor-induced RPE phagolysosomal maturation defects in Stargardt-like Maculopathy (STGD3). Sci Rep 8:5944.	OXPHOS	N S CIV NS ROX	Homogenate	Mouse	Endothelial;epithelial;mesothelial cell
Martinez-Palma 2018 Neurotherapeutics	2018	Martínez-Palma L, Miquel E, Lagos-Rodríguez V, Barbeito L, Cassina A, Cassina P (2018) Mitochondrial modulation by dichloroacetate reduces toxicity of aberrant glial cells and gliosis in the SOD1G93A rat model of amyotrophic lateral sclerosis. Neurotherapeutics 16:203-15.	LEAK ET	ROX	Intact cells	Rat	Nervous system
Zdralevic 2018 J Biol Chem	2018	Ždralević M, Brand A, Di Ianni L, Dettmer K, Reinders J, Singer K, Peter K, Schnell A, Bruss C, Decking SM, Koehl G, Felipe-Abrio B, Durivault J, Bayer P, Evangelista M, O'Brien T, Oefner PJ, Renner K, Pouysségur J, Kreutz M (2018) Double genetic disruption of lactate dehydrogenase A and B is required to ablate the 'Warburg effect' restricting tumor growth to oxidative metabolism. J Biol Chem 293:15947-61.	LEAK OXPHOS ET	N NS ROX	Permeabilized cells Intact cells	Human	Endothelial;epithelial;mesothelial cell
Monzio Compagnoni 2018 Biochim Biophys Acta Mol Basis Dis	2018	Monzio Compagnoni G, Kleiner G, Bordoni A, Fortunato F, Ronchi D, Salani S, Guida M, Corti C, Pichler I, Bergamini C, Fato R, Pellecchia MT, Vallelunga A, Del Sorbo F, Elia A, Reale C, Garavaglia B, Mora G, Albanese A, Cogiamanian F, Ardolino G, Bresolin N, Corti S, Comi GP, Quinzii CM, Di Fonzo A (2018) Mitochondrial dysfunction in fibroblasts of multiple system atrophy. Biochim Biophys Acta Mol Basis Dis 1864:3588-97.	OXPHOS ET ROUTINE	N S NS ROX	Permeabilized cells Intact cells	Human	Fibroblast
Chung 2018 J Exp Biol	2018	Chung DJ, Sparagna GC, Chicco AJ, Schulte PM (2018) Patterns of mitochondrial membrane remodeling parallel functional adaptations to thermal stress. J Exp Biol 221. pii: jeb174458.	LEAK OXPHOS ET	F N S CIV NS ROX	Isolated mitochondria	Fishes	Liver
Rodrigues 2018 Free Radic Biol Med	2018	Rodrigues NR, Macedo GE, Martins IK, Gomes KK, de Carvalho NR, Posser T, Franco JL (2018) Short-term sleep deprivation with exposure to nocturnal light alters mitochondrial bioenergetics in Drosophila. Free Radic Biol Med 120:395-406.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Drosophila
Giacco 2018 FASEB J	2018	Giacco A, Delli Paoli G, Senese R, Cioffi F, Silvestri E, Moreno M, Ruoppolo M, Caterino M, Costanzo M, Lombardi A, Goglia F, Lanni A, de Lange P (2018) The saturation degree of fatty acids and their derived acylcarnitines determines the direct effect of metabolically active thyroid hormones on insulin sensitivity in skeletal muscle cells. FASEB J 33:1811-23.	LEAK ET ROUTINE	ROX	Intact cells	Rat	Skeletal muscle
Belosludtsev 2018 Biochemistry (Mosc)	2018	Belosludtsev KN, Belosludtseva NV, Tenkov KS, Sharapov VA, Kosareva EA, Dubinin MV (2018) Effect of dequalinium on respiration and the inner membrane permeability of rat liver mitochondria. Biochemistry (Mosc) 12:121–27.	OXPHOS	ROX	Isolated mitochondria	Rat	Liver
Tsuda 2018 J Cachexia Sarcopenia Muscle	2018	Tsuda M, Fukushima A, Matsumoto J, Takada S, Kakutani N, Nambu H, Yamanashi K, Furihata T, Yokota T, Okita K, Kinugawa S, Anzai T (2018) Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure. J Cachexia Sarcopenia Muscle 9:844-59.	OXPHOS LEAK	F N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Trewin 2018 Am J Physiol Regul Integr Comp Physiol	2018	Trewin AJ, Parker L, Shaw CS, Hiam D, Garnham AP, Levinger I, McConell GK, Stepto NK (2018) Acute HIIE elicits similar changes in human skeletal muscle mitochondrial H₂O₂ release, respiration and cell signaling as endurance exercise even with less work. Am J Physiol Regul Integr Comp Physiol 315:R1003-R1016.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Nielsen 2018 Neurosci Lett	2018	Nielsen B, Cejvanovic V, Wörtwein G, Hansen AR, Marstal KK, Weimann A, Bjerring PN, Dela F, Poulsen HE, Jørgensen MB (2018) Increased oxidation of RNA despite reduced mitochondrial respiration after chronic electroconvulsive stimulation of rat brain tissue. Neurosci Lett 690:1-5.	LEAK OXPHOS ET	N NS ROX S	Homogenate	Rat	Nervous system
Houghton 2018 Free Radic Biol Med	2018	Houghton MJ, Kerimi A, Tumova S, Boyle JP, Williamson G (2018) Quercetin preserves redox status and stimulates mitochondrial function in metabolically-stressed HepG2 cells. Free Radic Biol Med 129:296-309.	LEAK ROUTINE ET	ROX	Intact cells	Human	Liver
Jelenik 2018 Diabetes	2018	Jelenik T, Flögel U, Álvarez-Hernández E, Scheiber D, Zweck E, Ding Z, Rothe M, Mastrototaro L, Kohlhaas V, Kotzka J, Knebel B, Müller-Wieland D, Moellendorf S, Gödecke A, Kelm M, Westenfeld R, Roden M, Szendroedi J (2018) Insulin resistance and vulnerability to cardiac ischemia. Diabetes 67:2695-702.	LEAK OXPHOS	F N NS ROX	Permeabilized tissue Isolated mitochondria	Human Mouse	Heart
Pardo 2018 FASEB J	2018	Pardo R, Vilà M, Cervela L, de Marco M, Gama-Pérez P, González-Franquesa A, Statuto L, Vilallonga R, Simó R, Garcia-Roves PM, Villena JA (2018) Calorie restriction prevents diet-induced insulin resistance independently of PGC-1-driven mitochondrial biogenesis in white adipose tissue. FASEB J 33:2343-58.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Fat
Haschka 2018 Mov Disord	2018	Haschka D, Volani C, Stefani A, Tymoszuk P, Mitterling T, Holzknecht E, Heidbreder A, Coassin S, Sumbalova Z, Seifert M, Dichtl S, Theurl I, Gnaiger E, Kronenberg F, Frauscher B, Högl B, Weiss G (2018) Association of mitochondrial iron deficiency and dysfunction with idiopathic restless legs syndrome. Mov Disord 34:114-23.	LEAK ROUTINE ET	ROX	Intact cells	Human	Blood cells Lymphocyte
Tosi 2018 J Bioenerg Biomembr	2018	Tosi I, Art T, Cassart D, Farnir F, Ceusters J, Serteyn D, Lemieux H, Votion DM (2018) Altered mitochondrial oxidative phosphorylation capacity in horses suffering from polysaccharide storage myopathy. J Bioenerg Biomembr 50:379-90.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Horse	Skeletal muscle
Ejarque 2018 Int J Obes (Lond)	2018	Ejarque M, Ceperuelo-Mallafré V, Serena C, Maymo-Masip E, Duran X, Díaz-Ramos A, Millan-Scheiding M, Núñez-Álvarez Y, Núñez-Roa C, Gama P, Garcia-Roves PM, Peinado MA, Gimble JM, Zorzano A, Vendrell J, Fernández-Veledo S (2018) Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells. Int J Obes (Lond) 43:1256-68.	LEAK ROUTINE ET	CIV ROX	Intact cells	Human	Fat
Ahn 2018 Redox Biol	2018	Ahn B, Pharaoh G, Premkumar P, Huseman K, Ranjit R, Kinter M, Szweda L, Kiss T, Fulop G, Tarantini S, Csiszar A, Ungvari Z, Van Remmen H (2018) Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass. Redox Biol 17:47-58.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Dias 2018 Anal Biochem	2018	Dias C, Lourenco CF, Barbosa RM, Laranjinha J, Ledo A (2018) Analysis of respiratory capacity in brain tissue preparations: high-resolution respirometry for intact hippocampal slices. Anal Biochem 551:43-50.	LEAK ROUTINE ET	ROX	Intact cells	Mouse Rat	Nervous system
Teulier 2018 J Fish Biol	2018	Teulier L, Guillard L, Leon C, Romestaing C, Voituron Y (2018) Consequences of electroshock-induced narcosis in fish muscle: from mitochondria to swim performance. J Fish Biol 92:1805-18.	OXPHOS ET	N NS ROX	Intact cells	Fishes Zebrafish	Skeletal muscle
Lo 2018 Am J Physiol Renal Physiol	2018	Lo S, MacMillan-Crow LA, Parajuli N (2018) Renal cold storage followed by transplantation impairs proteasome function and subsequently mitochondrial protein homeostasis. Am J Physiol Renal Physiol 316:F42-F53.	OXPHOS LEAK	N S ROX	Permeabilized cells	Rat	Kidney Other cell lines
Merz 2018 Intensive Care Med Exp	2018	Merz T, Wepler M, Nußbaum B, Vogt J, Calzia E, Wang R, Szabo C, Radermacher P, McCook O (2018) Cystathionine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis. Intensive Care Med Exp 6:43.	LEAK OXPHOS ET	F N S NS ROX	Homogenate	Pig	Kidney
Zhang 2018 Aging Dis	2018	Zhang L, Hao J, Zheng Y, Su R, Liao Y, Gong X, Liu L, Wang X (2018) Fucoidan protects dopaminergic neurons by enhancing the mitochondrial function in a rotenone-induced rat model of Parkinson’s disease. Aging Dis 9:590-604.	LEAK OXPHOS ET	N S ROX	Permeabilized tissue Homogenate	Rat	Nervous system
Ko 2018 Pflugers Arch	2018	Ko TH, Marquez JC, Kim HK, Jeong SH, Lee S, Youm JB, Song IS, Seo DY, Kim HJ, Won DN, Cho KI, Choi MG, Rhee BD, Ko KS, Kim N, Won JC, Han J (2018) Resistance exercise improves cardiac function and mitochondrial efficiency in diabetic rat hearts. Pflugers Arch 470:263-75.	LEAK OXPHOS	N ROX	Isolated mitochondria	Rat	Heart
Rocha 2018 J Physiol Biochem	2018	Rocha C, Koury OH, Scheede-Bergdahl C, Bergdahl A (2018) Cardiac mitochondrial respiration following a low-carbohydrate, high-fat diet in apolipoprotein E-deficient mice. J Physiol Biochem 75:65-72.	LEAK OXPHOS ET	F N CIV NS ROX	Permeabilized tissue	Mouse	Heart
Arnoux 2018 Elife	2018	Arnoux I, Willam M, Griesche N, Krummeich J, Watari H, Offermann N, Weber S, Narayan Dey P, Chen C, Monteiro O, Buettner S, Meyer K, Bano D, Radyushkin K, Langston R, Lambert JJ, Wanker E, Methner A, Krauss S, Schweiger S, Stroh A (2018) Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease. Elife 7:e38744.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Reyes 2018 EMBO Mol Med	2018	Reyes A, Melchionda L, Burlina A, Robinson AJ, Ghezzi D, Zeviani M (2018) Mutations in TIMM50 compromise cell survival in OxPhos-dependent metabolic conditions. EMBO Mol Med 10:e8698.	LEAK ET	ROX	Intact cells	Human	Fibroblast
Laouafa 2018 Adv Exp Med Biol	2018	Laouafa S, Roussel D, Marcouiller F, Soliz J, Bairam A, Joseph V (2018) Role of estradiol receptor beta (ERβ) on arterial pressure, respiratory chemoreflex and mitochondrial function in young and aged female mice. Adv Exp Med Biol 1071:115-27.	LEAK OXPHOS ET	N S CIV ROX	Permeabilized tissue	Mouse	Nervous system
Fischer 2018 BMC Musculoskelet Disord	2018	Fischer MJ, Horvath G, Krismer M, Gnaiger E, Goebel G, Pesta DH (2018) Evaluation of mitochondrial function in chronic myofascial trigger points - a prospective cohort pilot study using high-resolution respirometry. BMC Musculoskelet Disord 19:388.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Doucet 2018 Mol Pharmacol	2018	Doucet MS, Jougleux JL, Poirier SJ, Cormier M, Leger JL, Surette ME, Pichaud N, Touaibia M, Boudreau LH (2018) Identification of peracetylated quercetin as a selective 12-lipoxygenase pathway inhibitor in human platelets. Mol Pharmacol 95:139-50.	LEAK ROUTINE ET	ROX	Intact cells	Human	Platelet Blood cells
MacMillan 2017 Front Physiol	2017	MacMillan NJ, Kapchinsky S, Konokhova Y, Gouspillou G, de Sousa Sena R, Jagoe RT, Baril J, Carver TE, Andersen RE, Richard R, Perrault H, Bourbeau J, Hepple RT, Taivassalo T (2017) Eccentric ergometer training promotes locomotor muscle strength but not mitochondrial adaptation in patients with severe chronic obstructive pulmonary disease. Front Physiol 8:114.	OXPHOS	N CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Friederich 2017 Hum Mol Genet	2017	Friederich MW, Erdogan AJ, Coughlin CR 2nd, Elos MT, Jiang H, O'Rourke CP, Lovell MA, Wartchow E, Gowan K, Chatfield KC, Chick WS, Spector EB, Van Hove JLK, Riemer J (2017) Mutations in the accessory subunit NDUFB10 result in isolated complex I deficiency and illustrate the critical role of intermembrane space import for complex I holoenzyme assembly. Hum Mol Genet 26:702-16.	ROUTINE OXPHOS ET LEAK	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Fibroblast
Jezek 2017 Biochim Biophys Acta	2017	Ježek J, Engstová H, Ježek P (2017) Antioxidant mechanism of mitochondria-targeted plastoquinone SkQ1 is suppressed in aglycemic HepG2 cells dependent on oxidative phosphorylation. Biochim Biophys Acta 1858:750-62.	ET ROUTINE	ROX	Intact cells	Human	Liver
Sharaf 2017 Aquat Toxicol	2017	Sharaf MS, Stevens D, Kamunde C (2017) Zinc and calcium alter the relationship between mitochondrial respiration, ROS and membrane potential in rainbow trout (Oncorhynchus mykiss) liver mitochondria. Aquat Toxicol 189:170-83.	LEAK OXPHOS ET	ROX N	Isolated mitochondria	Fishes	Liver
Sharaf 2017 Biochim Biophys Acta	2017	Sharaf MS, Stevens D, Kamunde C (2017) Mitochondrial transition ROS spike (mTRS) results from coordinated activities of complex I and nicotinamide nucleotide transhydrogenase. Biochim Biophys Acta 1858:955-65.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Mouse Fishes	Heart Liver
Luethi 2017 Toxicology	2017	Luethi D, Liechti ME, Krähenbühl S (2017) Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones. Toxicology 387:57-66.	OXPHOS ET	NS N S DQ CIV ROX	Permeabilized cells	Human	Liver
Alves 2017 Free Radic Biol Med	2017	Alves de Souza CE, Alves de Souza HM, Stipp MC, Corso CR, Galindo CM, Cardoso CR, Dittrich RL, de Souza Ramos EA, Klassen G, Carlos RM, Correia Cadena SMS, Acco A (2017) Ruthenium complex exerts antineoplastic effects that are mediated by oxidative stress without inducing toxicity in Walker-256 tumor-bearing rats. Free Radic Biol Med 110:228-39.	LEAK ROUTINE	ROX		Rat
Emmett 2017 Nature	2017	Emmett MJ, Lim HW, Jager J, Richter HJ, Adlanmerini M, Peed LC, Briggs ER, Steger DJ, Ma T, Sims CA, Baur JA, Pei L, Won KJ, Seale P, Gerhart-Hines Z, Lazar MA (2017) Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge. Nature 546:544-8.	LEAK OXPHOS	F N S CIV ROX	Homogenate	Mouse	Fat
Yeh 2017 Aquat Toxicol	2017	Yeh A, Marcinek DJ, Meador JP, Gallagher EP (2017) Effect of contaminants of emerging concern on liver mitochondrial function in Chinook salmon. Aquat Toxicol 190:21-31.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Fishes	Liver
Merz 2017 Intensive Care Med Exp	2017	Merz T, Vogt JA, Wachter U, Calzia E, Szabo C, Wang R, Radermacher P, McCook O (2017) Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock. Intensive Care Med Exp 5:30.	LEAK OXPHOS ET	F N S NS ROX	Homogenate	Mouse	Liver
Holland 2017 Placenta	2017	Holland OJ, Hickey AJR, Alvsaker A, Moran S, Hedges C, Chamley LW, Perkins AV (2017) Changes in mitochondrial respiration in the human placenta over gestation. Placenta 57:102-12.	LEAK ROUTINE OXPHOS	F N CIV NS ROX	Permeabilized cells Intact cells		Genital
Cunha de Padua 2017 Carbohydr Polym	2017	Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Toxicity of native and oxovanadium (IV/V) galactomannan complexes on HepG2 cells is related to impairment of mitochondrial functions. Carbohydr Polym 173:665-75.	LEAK ROUTINE ET	ROX		Human	Liver
Van Schaardenburgh 2017 J Transl Med	2017	van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson EJR (2017) Exercise in claudicants increase or decrease walking ability and the response relates to mitochondrial function. J Transl Med 15:130.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Ounpuu 2017 Biochim Biophys Acta	2017	Ounpuu L, Klepinin A, Pook M, Teino I, Peet N, Paju K, Tepp K, Chekulayev V, Shevchuk I, Koks S, Maimets T, Kaambre T (2017) 2102Ep embryonal carcinoma cells have compromised respiration and shifted bioenergetic profile distinct from H9 human embryonic stem cells. Biochim Biophys Acta 1861:2146-54.	LEAK ROUTINE OXPHOS ET	N S NS ROX CIV	Permeabilized cells Intact cells	Human	Stem cells
Irgebay 2017 Breast	2017	Irgebay Z, Yeszhan B, Sen B, Tuleukhanov S, Brooks AD, Sensenig R, Orynbayeva Z (2017) Danazol alters mitochondria metabolism of fibrocystic breast Mcf10A cells. Breast 35:55-62.	ET	N S CIV NS ROX	Permeabilized cells	Human	Genital
Rodrigues-Silva 2017 J Neurooncol	2017	Rodrigues-Silva E, Siqueira-Santos ES, Ruas JS, Ignarro RS, Figueira TR, Rogério F, Castilho RF (2017) Evaluation of mitochondrial respiratory function in highly glycolytic glioma cells reveals low ADP phosphorylation in relation to oxidative capacity. 10.1007/s11060-017-2482-0	LEAK ROUTINE OXPHOS ET	N ROX	Permeabilized cells Isolated mitochondria Intact cells	Rat	Nervous system
Svensson 2017 Acta Physiol (Oxf)	2017	Svensson K, LaBarge SA, Martins VF, Schenk S (2017) Temporal overexpression of SIRT1 in skeletal muscle of adult mice does not improve insulin sensitivity or markers of mitochondrial biogenesis. Acta Physiol (Oxf) 221:193-203.	OXPHOS ET LEAK	F N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Paech 2017 Arch Toxicol	2017	Paech F, Messner S, Spickermann J, Wind M, Schmitt-Hoffmann AH, Witschi AT, Howell BA, Church RJ, Woodhead J, Engelhardt M, Krähenbühl S, Maurer M (2017) Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072. Arch Toxicol 91:3647-62.	LEAK OXPHOS ET	N S DQ CIV ROX	Permeabilized cells	Human	Liver Other cell lines
Kake 2017 J Therm Biol	2017	Kake Guena SA, Touisse K, Warren BE, Scott KY, Dufresne F, Blier PU, Lemieux H (2017) Temperature-related differences in mitochondrial function among clones of the cladoceran Daphnia pulex. J Therm Biol 69:23-31.	LEAK OXPHOS	N CIV NS S ROX	Permeabilized tissue	Crustaceans
Li 2017 Oxid Med Cell Longev	2017	Li CJ, Chen PK, Sun LY, Pang CY (2017) Enhancement of mitochondrial transfer by antioxidants in human mesenchymal stem cells. Oxid Med Cell Longev 2017:8510805.	ET LEAK ROUTINE	ROX	Intact cells	Human	Fat
Thaher 2017 Neurochem Int	2017	Thaher O, Wolf C, Dey PN, Pouya A, Wüllner V, Tenzer S, Methner A (2017) The thiol switch C684 in Mitofusin-2 mediates redox-induced alterations of mitochondrial shape and respiration. Neurochem Int 117:167-73.	LEAK ROUTINE OXPHOS ET	N NS ROX	Intact cells Permeabilized cells	Mouse	Fibroblast
Jelenik 2017 Diabetes	2017	Jelenik T, Kaul K, Séquaris G, Flögel U, Phielix E, Kotzka J, Knebel B, Fahlbusch P, Hörbelt T, Lehr S, Reinbeck AL, Müller-Wieland D, Esposito I, Shulman GI, Szendroedi J, Roden M (2017) Mechanisms of insulin resistance in primary and secondary nonalcoholic fatty liver. Diabetes 66:2241-53.	LEAK OXPHOS ET	F N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle Liver
Rodolphi 2017 Thesis	2017	Rodolphi MS (2017) Efeitos da nandrolona e da ceftriaxona na homeostasia glutamatérgica: uma busca por mecanismos interativos entre astrócitos e neurônios envolvidos no comportamento agressivo. Dissertation p58.	ROUTINE OXPHOS	S CIV ROX	Homogenate	Mouse	Nervous system
Newsom 2017 Am J Physiol Endocrinol Metab	2017	Newsom SA, Miller BF, Hamilton KL, Ehrlicher SE, Stierwalt HD, Robinson MM (2017) Long-term rates of mitochondrial protein synthesis are increased in mouse skeletal muscle with high fat feeding regardless of insulin sensitizing treatment. Am J Physiol Endocrinol Metab 313:552-62.	LEAK OXPHOS ET	F N S NS ROX	Isolated mitochondria	Mouse	Skeletal muscle
Gruenig 2017 Toxicol In Vitro	2017	Grünig D, Felser A, Bouitbir J, Krähenbühl S (2017) The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells. Toxicol In Vitro 42:337-47.	LEAK OXPHOS ET	N S CIV ROX	Isolated mitochondria Permeabilized cells	Human Mouse	Liver Other cell lines
Duicu 2017 Can J Physiol Pharmacol	2017	Duicu OM, Privistirescu A, Wolf A, Petruş A, Dănilă MD, Raţiu CD, Muntean DM, Sturza A (2017) Methylene blue improves mitochondrial respiration and decreases oxidative stress in a substrate-dependent manner in diabetic rat hearts. Can J Physiol Pharmacol 95:1376-82.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Rat	Heart
Michalak 2017 Oxid Med Cell Longev	2017	Michalak S, Florczak-Wyspiańska J, Rybacka-Mossakowska J, Ambrosius W, Osztynowicz K, Baszczuk A, Kozubski W, Wysocka E (2017) Mitochondrial respiration in intact peripheral blood mononuclear cells and sirtuin 3 activity in patients with movement disorders. Oxid Med Cell Longev 2017:9703574.	LEAK ROUTINE ET	ROX	Intact cells		Blood cells
Trewin 2017 PLOS ONE	2017	Trewin AJ, Levinger I, Parker L, Shaw CS, Serpiello FR, Anderson MJ, McConell GK, Hare DL, Stepto NK (2017) Acute exercise alters skeletal muscle mitochondrial respiration and H₂O₂ emission in response to hyperinsulinemic-euglycemic clamp in middle-aged obese men. PLOS ONE 12:e0188421.	LEAK OXPHOS ET	F N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Xiong 2017 J Am Heart Assoc	2017	Xiong S, Wang B, Lin S, Zhang H, Li Y, Wei X, Cui Y, Wei X, Lu Z, Gao P, Li L, Zhao Z, Liu D, Zhu Z (2017) Activation of transient receptor potential melastatin subtype 8 attenuates cold-induced hypertension through ameliorating vascular mitochondrial dysfunction. J Am Heart Assoc 6. pii: e005495.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Mouse	Endothelial;epithelial;mesothelial cell
Zhou 2017 Biochim Biophys Acta	2017	Zhou L, Wang W, Hoppel C, Liu J, Zhu X (2017) Parkinson's disease-associated pathogenic VPS35 mutation causes complex I deficits. Biochim Biophys Acta 1863:2791-5.	OXPHOS ET	N S NS ROX	Isolated mitochondria	Human	Fibroblast
Han 2017 Invest Ophthalmol Vis Sci	2017	Han WH, Gotzmann J, Kuny S, Huang H, Chan CB, Lemieux H, Sauvé Y (2017) Modifications in retinal mitochondrial respiration precede type 2 diabetes and protracted microvascular retinopathy. Invest Ophthalmol Vis Sci 58:3826-39.	LEAK OXPHOS	N S CIV NS ROX	Homogenate	Rat	Nervous system
Carraro 2017 Mol Cell Endocrinol	2017	Carraro RS, Souza GF, Solon C, Razolli DS, Chausse B, Barbizan R, Victorio SC, Velloso LA (2017) Hypothalamic mitochondrial abnormalities occur downstream of inflammation in diet-induced obesity. Mol Cell Endocrinol 460:238-45.	LEAK OXPHOS	N ROX	Permeabilized tissue	Mouse	Nervous system
Rowley 2017 J Nutr Biochem	2017	Rowley TJ, Bitner BF, Ray JD, Lathen DR, Smithson AT, Dallon BW, Plowman CJ, Bikman BT, Hansen JM, Dorenkott MR, Goodrich KM, Ye L, O'Keefe SF, Neilson AP, Tessem JS (2017) Monomeric cocoa catechins enhance β-cell function by increasing mitochondrial respiration. J Nutr Biochem 49:30-41.	OXPHOS ET	N S NS ROX	Permeabilized cells	Rat	Islet cell;pancreas;thymus
Asping 2017 Eur J Clin Pharmacol	2017	Asping M, Stride N, Søgaard D, Dohlmann TL, Helge JW, Dela F, Larsen S (2017) The effects of 2 weeks of statin treatment on mitochondrial respiratory capacity in middle-aged males: the LIFESTAT study. Eur J Clin Pharmacol 73:679-87.	LEAK ET	F N S CIV NS ROX	Permeabilized tissue	Human
Jang 2017 Clin Toxicol (Phila)	2017	Jang DH, Kelly M, Hardy K, Lambert DS, Shofer FS, Eckmann DM (2017) A preliminary study in the alterations of mitochondrial respiration in patients with carbon monoxide poisoning measured in blood cells. Clin Toxicol (Phila) 55:579-84.	LEAK ROUTINE OXPHOS ET	F S CIV NS ROX	Intact cells		Blood cells
Bohanon 2017 Shock	2017	Bohanon FJ, Lopez ON, Herndon DN, Wang X, Bhattarai N, Ayadi AE, Prasai A, Jay JW, Rojas-Khalil Y, Toliver-Kinsky TE, Finnerty CC, Radhakrishnan RS, Porter C (2017) Burn trauma acutely increases the respiratory capacity and function of liver mitochondria. Shock 49:466-73.	LEAK OXPHOS ET	F N ROX	Intact cells	Mouse	Liver
Kake-Guena 2017 J Therm Biol	2017	Kake-Guena SA, Touisse K, Warren BE, Scott KY, Blier PU, Lemieux H (2017) Temperature-related differences in mitochondrial function among clones of the cladoceran Daphnia pulex. J Therm Biol 69:23-31.	LEAK OXPHOS	S Gp CIV NS ROX	Permeabilized tissue	Crustaceans
Wang 2017 J Am Heart Assoc	2017	Wang B, Xiong S, Lin S, Xia W, Li Q, Zhao Z, Wei X, Lu Z, Wei X, Gao P, Liu D, Zhu Z (2017) Enhanced mitochondrial transient receptor potential channel, canonical type 3-mediated calcium handling in the vasculature from hypertensive rats. J Am Heart Assoc 6. pii: e005812.	ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Rat	Endothelial;epithelial;mesothelial cell
Broatch 2017 Am J Physiol Regul Integr Comp Physiol	2017	Broatch JR, Petersen A, Bishop DJ (2017) Cold-water immersion following sprint interval training does not alter endurance signaling pathways or training adaptations in human skeletal muscle. Am J Physiol Regul Integr Comp Physiol 313:R372-84.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Jang 2017 Biol Open	2017	Jang DH, Seeger SC, Grady ME, Shofer FC, Eckmann DM (2017) Mitochondrial dynamics and respiration within cells with increased open pore cytoskeletal meshes. Biol Open 6:1831-9.	LEAK ROUTINE ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Endothelial;epithelial;mesothelial cell Fibroblast
Volani 2017 Metallomics	2017	Volani C, Doerrier C, Demetz E, Haschka D, Paglia G, Lavdas AA, Gnaiger E, Weiss G (2017) Dietary iron loading negatively affects liver mitochondrial function. Metallomics 9:1634-44.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Liver
Thomas 2017 Thesis	2017	Thomas NO (2017) Age-related decrease in resilience against acute redox cycling agents: critical role of declining GSH-dependent detoxification capacity. Dissertation p141.	LEAK OXPHOS ET	N NS ROX	Permeabilized cells Intact cells	Rat	Liver
Zeidler 2017 J Biol Chem	2017	Zeidler JD, Fernandes-Siqueira LO, Carvalho AS, Cararo-Lopes E, Dias MH, Ketzer LA, Galina A, Da Poian AT (2017) Short-term starvation is a strategy to unravel the cellular capacity of oxidizing specific exogenous/endogenous substrates in mitochondria. J Biol Chem 292:14176-87.	LEAK ROUTINE ET	F N ROX	Intact cells	Mouse
Greggio 2017 Cell Metab	2017	Greggio C, Jha P, Kulkarni SS, Lagarrigue S, Broskey NT, Boutant M, Wang X, Alonso SC, Ofori E, Auwerx J, Cantó C, Amati F (2017) Enhanced respiratory chain supercomplex formation in response to exercise in human skeletal muscle. Cell Metab 25:301-11.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Theisen 2017 Am J Med Genet A	2017	Theisen BE, Rumyantseva A, Cohen JS, Alcaraz WA, Shinde DN, Tang S, Srivastava S, Pevsner J, Trifunovic A, Fatemi A (2017) Deficiency of WARS2, encoding mitochondrial tryptophanyl tRNA synthetase, causes severe infantile onset leukoencephalopathy. Am J Med Genet A 173:2505-10.	LEAK ROUTINE ET	ROX	Intact cells	Human	Endothelial;epithelial;mesothelial cell Fibroblast
Lau 2017 Mol Biol Evol	2017	Lau GY, Mandic M, Richards JG (2017) Evolution of cytochrome c oxidase in hypoxia tolerant Sculpins (Cottidae, Actinopterygii). Mol Biol Evol 34:2153-62.	LEAK OXPHOS ET	CIV NS ROX	Isolated mitochondria	Fishes	Nervous system
Braz-Mota 2017 Thesis	2017	Braz Mota S (2017) Estudo comparativo da toxicidade e dos mecanismos de ação tóxica de nanopartículas de cobre e cobre em duas espécies de peixes da Amazônia: Apistogramma agassizii e Paracheirodon axelrodi. Dissertation p.78.	LEAK OXPHOS ET	N NS ROX	Homogenate	Fishes	Lung;gill
Morrow 2017 Proc Natl Acad Sci U S A	2017	Morrow RM, Picard M, Derbeneva O, Leipzig J, McManus MJ, Gouspillou G, Barbat-Artigas S, Dos Santos C, Hepple RT, Murdock DG, Wallace DC (2017) Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity. Proc Natl Acad Sci U S A 114:2705-10.	ROUTINE OXPHOS LEAK	N NS ROX Other combinations	Permeabilized tissue		Skeletal muscle
Napa 2017 Int J Dent	2017	Napa K, Baeder AC, Witt JE, Rayburn ST, Miller MG, Dallon BW, Gibbs JL, Wilcox SH, Winden DR, Smith JH, Reynolds PR, Bikman BT (2017) LPS from P. gingivalis negatively alters gingival cell mitochondrial bioenergetics. Int J Dent 2017:2697210.	LEAK OXPHOS ET	N NS ROX	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell
Tepp 2017 Mol Cell Biochem	2017	Tepp K, Puurand M, Timohhina N, Adamson J, Klepinin A, Truu L, Shevchuk I, Chekulayev V, Kaambre T (2017) Changes in the mitochondrial function and in the efficiency of energy transfer pathways during cardiomyocyte aging. Mol Cell Biochem 432:141-58.	OXPHOS LEAK	N S CIV ROX	Permeabilized cells	Rat	Heart
Chavanelle 2017 Sci Rep	2017	Chavanelle V, Boisseau N, Otero YF, Combaret L, Dardevet D, Montaurier C, Delcros G, Peltier SL, Sirvent P (2017) Effects of high-intensity interval training and moderate-intensity continuous training on glycaemic control and skeletal muscle mitochondrial function in db/db mice. Sci Rep 7:204.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Van Schaardenburgh 2017 J Vasc Surg	2017	Van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson E (2017) Calf raise exercise increases walking performance in patients with intermittent claudication. J Vasc Surg 65:1473-82.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Ljones 2017 PLOS ONE	2017	Ljones K, Ness HO, Solvang-Garten K, Gaustad SE, Andre Høydal M (2017) Acute exhaustive aerobic exercise training impair cardiomyocyte function and calcium handling in Sprague-Dawley rats. PLOS ONE 12:e0173449.	OXPHOS ET LEAK	N S CIV NS ROX	Permeabilized tissue	Rat	Heart
Ortega 2017 Biol Reprod	2017	Ortega MS, Wohlgemuth S, Tribulo P, Siqueira LG, Null DJ, Cole JB, Da Silva MV, Hansen PJ (2017) A single nucleotide polymorphism in COQ9 affects mitochondrial and ovarian function and fertility in Holstein cows. Biol Reprod 96:652-63.	LEAK ROUTINE ET	ROX		Bovines	Blood cells
Miller 2017 PLOS ONE	2017	Miller B, Hamilton K, Boushel R, Williamson K, Laner V, Gnaiger E, Davis M (2017) Mitochondrial respiration in highly aerobic canines in the non-raced state and after a 1600-km sled dog race. PLOS ONE 12:e0174874.	OXPHOS ET LEAK	F N S NS ROX	Permeabilized tissue	Dog	Skeletal muscle
Makrecka-Kuka 2017 Toxicol Lett	2017	Makrecka-Kuka M, Volska K, Antone U, Vilskersts R, Grinberga S, Bandere D, Liepinsh E, Dambrova M (2017) Trimethylamine N-oxide impairs pyruvate and fatty acid oxidation in cardiac mitochondria. Toxicol Lett 267:32-8.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Mouse	Heart
Davis 2017 Tissue Eng Part C Methods	2017	Davis BN, Santoso JW, Walker MJ, Cheng CS, Koves TR, Kraus WE, Truskey GA (2017) Human, tissue-engineered, skeletal muscle myobundles to measure oxygen uptake and assess mitochondrial toxicity. Tissue Eng Part C Methods 23:189-99.	LEAK ROUTINE ET	ROX	Intact cells	Human	Skeletal muscle
Profilo 2017 Biochim Biophys Acta	2017	Profilo E, Peña-Altamira LE, Corricelli M, Castegna A, Danese A, Agrimi G, Petralla S, Giannuzzi G, Porcelli V, Sbano L, Viscomi C, Massenzio F, Palmieri EM, Giorgi C, Fiermonte G, Virgili M, Palmieri L, Zeviani M, Pinton P, Monti B, Palmieri F, Lasorsa FM (2017) Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells. Biochim Biophys Acta 1863:1422-35.	LEAK ET ROUTINE	ROX	Intact cells	Mouse	Nervous system Other cell lines Neuroblastoma
Cunha 2017 Int J Biol Macromol	2017	Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Galactomannan from Schizolobium amazonicum seed and its sulfated derivatives impair metabolism in HepG2 cells. Int J Biol Macromol 101:64-473.	LEAK ROUTINE ET	ROX	Intact cells	Human	Liver
Goncalves 2017 J Cell Commun Signal	2017	Gonçalves R, Zamoner A, Zanatta L, Zanatta AP, Remor AP, da Luz Scheffer D, Latini A, Silva FR (2017) 1,25(OH)2 vitamin D₃ signalling on immature rat Sertoli cells: gamma-glutamyl transpeptidase and glucose metabolism. J Cell Commun Signal 11:233-43.	LEAK ROUTINE ET	ROX	Intact cells	Rat	Genital
Yang 2017 Cell Death Dis	2017	Yang N, Weinfeld M, Lemieux H, Montpetit B, Goping IS (2017) Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis. Cell Death Dis 8:e2587.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Saccharomyces cerevisiae Human	Lymphocyte
Haegler 2017 PLOS ONE	2017	Haegler P, Grünig D, Berger B, Terracciano L, Krähenbühl S, Bouitbir J (2017) Hepatic effects of pharmacological doses of hydroxy-cobalamin[c-lactam] in mice. PLOS ONE 12:e0171026.	LEAK OXPHOS ET	N S CIV ROX DQ	Homogenate	Mouse	Liver
Mantilla 2017 PLOS Pathog	2017	Mantilla BS, Marchese L, Casas-Sánchez A, Dyer NA, Ejeh N, Biran M, Bringaud F, Lehane MJ, Acosta-Serrano A, Silber AM (2017) Proline metabolism is essential for Trypanosoma brucei brucei survival in the tsetse vector. PLOS Pathog 13:e1006158.	LEAK OXPHOS ET ROUTINE	S ROX N	Permeabilized cells Intact cells	Protists
Calcutt 2017 J Clin Invest	2017	Calcutt NA, Smith DR, Frizzi K, Sabbir MG, Chowdhury SK, Mixcoatl-Zecuatl T, Saleh A, Muttalib N, Van der Ploeg R, Ochoa J, Gopaul A, Tessler L, Wess J, Jolivalt CG, Fernyhough P (2017) Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy. J Clin Invest 127:608-22.	LEAK OXPHOS ET	N CIV ROX	Isolated mitochondria	Rat	Nervous system
Khalifa 2017 Physiol Rep	2017	Khalifa AR, Abdel-Rahman EA, Mahmoud AM, Ali MH, Noureldin M, Saber SH, Mohsen M, Ali SS (2017) Sex-specific differences in mitochondria biogenesis, morphology, respiratory function, and ROS homeostasis in young mouse heart and brain. Physiol Rep 5. pii: e13125.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Mouse	Heart Nervous system
Jespersen 2017 J Physiol	2017	Jespersen NR, Yokota T, Støttrup NB, Bergdahl A, Paelestik KB, Povlsen JA, Dela F, Bøtker HE (2017) Pre-ischaemic mitochondrial substrate constraint by inhibition of malate-aspartate shuttle preserves mitochondrial function after ischaemia-reperfusion. J Physiol 595:3765-80.	LEAK OXPHOS	F N NS ROX S	Permeabilized tissue	Rat	Heart
Garcia-Neto 2017 PLOS ONE	2017	Garcia-Neto W, Cabrera-Orefice A, Uribe-Carvajal S, Kowaltowski AJ, Luévano-Martínez LA (2017) High osmolarity environments activate the mitochondrial alternative oxidase in Debaryomyces Hansenii. PLOS ONE 12:e0169621. https://doi.org/10.1371/journal.pone.0169621	ROUTINE	CIV ROX	Isolated mitochondria Intact cells	Fungi
Harisseh 2017 Basic Res Cardiol	2017	Harisseh R, Pillot B, Gharib A, Augeul L, Gallo-Bona N, Ferrera R, Loufouat J, Delale T, Allas S, Abribat T, Crola Da Silva C, Ovize M (2017) Unacylated ghrelin analog prevents myocardial reperfusion injury independently of permeability transition pore. Basic Res Cardiol 112:4.	OXPHOS ET	N S CIV ROX	Permeabilized cells	Mouse	Heart
Maddalena 2017 Biochim Biophys Acta	2017	Maddalena LA, Ghelfi M, Atkinson J, Stuart JA (2017) The mitochondria-targeted imidazole substituted oleic acid 'TPP-IOA' affects mitochondrial bioenergetics and its protective efficacy in cells is influenced by cellular dependence on aerobic metabolism. Biochim Biophys Acta 1858:73-85.	OXPHOS	ROX	Isolated mitochondria	Rat	Liver
Koit 2017 Oxid Med Cell Longev	2017	Koit A, Shevchuk I, Ounpuu L, Klepinin A, Chekulayev V, Timohhina N, Tepp K, Puurand M,Truu L, Heck K, Valvere V, Guzun R, Kaambre T (2017) Mitochondrial respiration in human colorectal and breast cancer clinical material is regulated differently. Oxid Med Cell Longev 2017:1372640.	OXPHOS LEAK	N S CIV ROX NS	Permeabilized tissue	Human	Endothelial;epithelial;mesothelial cell
Rezania 2017 Thromb Res	2017	Rezania S, Puskarich MA, Petrusca DN, Neto-Neves EM, Rondina MT, Kline JA (2017) Platelet hyperactivation, apoptosis and hypercoagulability in patients with acute pulmonary embolism. Thromb Res 155:106-15.	LEAK ROUTINE ET	ROX	Intact cells	Human	Blood cells Platelet
Chang 2017 J Biol Chem	2017	Chang JS, Ha K (2017) An unexpected role for the transcriptional coactivator isoform NT-PGC-1α in the regulation of mitochondrial respiration in brown adipocytes. J Biol Chem 292:9958-66.	LEAK ET ROUTINE	ROX	Intact cells	Mouse	Fat
De Carvalho 2017 Toxicol Research	2017	de Carvalho NR, Rodrigues NR, Macedo GE, Boligon AA, de Campos MM, Posser T, Cunha FAB, Coutinho HD, Klamt F, Bristot IJ, Merritt TJS, Franco JL (2017) Eugenia uniflora leaves essential oil promotes mitochondrial dysfunction in Drosophila melanogaster through the inhibition of oxidative phosphorylation. Toxicol Research 6:526-34 .	LEAK OXPHOS ET	F N NS ROX S	Isolated mitochondria	Drosophila
Varga 2017 Inflammopharmacology	2017	Varga G, Ugocsai M, Hartmann P, Lajkó N, Molnár R, Szűcs S, Jász DK, Érces D, Ghyczy M, Tóth G, Boros M (2017) Acetylsalicylic acid-tris-hydroxymethyl-aminomethane reduces colon mucosal damage without causing gastric side effects in a rat model of colitis. Inflammopharmacology 26:261-71.	OXPHOS LEAK	N S CIV NS ROX	Isolated mitochondria	Rat	Liver
Bernardinelli 2017 PLoS One	2017	Bernardinelli E, Costa R, Scantamburlo G, To J, Morabito R, Nofziger C, Doerrier C, Krumschnabel G, Paulmichl M, Dossena S (2017) Mis-targeting of the mitochondrial protein LIPT2 leads to apoptotic cell death. PLoS One 12(6):e0179591.	LEAK ROUTINE ET	ROX	Intact cells	Human	Kidney
Kyhl 2017 Peptides	2017	Kyhl K, Lønborg J, Hartmann B, Kissow H, Poulsen SS, Ali HE, Kjær A, Dela F, Engstrøm T, Treiman M (2017) Lack of effect of prolonged treatment with liraglutide on cardiac remodeling in rats after acute myocardial infarction. Peptides 93:1-12.	OXPHOS LEAK	F N S NS ROX	Permeabilized tissue	Rat	Heart
Vienne 2017 Anal Biochem	2017	Vienne JC, Cimetta C, Dubois M, Duburcq T, Favory R, Dessein AF, Fontaine M, Joncquel-Chevalier Curt M, Cuisset JM, Douillard C, Mention-Mulliez K, Dobbelaere D, Vamecq J (2017) A fast method for high resolution oxymetry study of skeletal muscle mitochondrial respiratory chain complexes. Anal Biochem 528:57-62.	LEAK OXPHOS ET	N CIV ROX S	Homogenate Permeabilized tissue	Pig	Skeletal muscle
Du 2017 Evolution	2017	Du SNN, Khajali F, Dawson NJ, Scott GR (2017) Hybridization increases mitochondrial production of reactive oxygen species in sunfish. Evolution 71:1643-52.	LEAK OXPHOS ET	N NS ROX S	Isolated mitochondria	Fishes	Liver
Mathers 2017 J Comp Physiol B	2017	Mathers KE, McFarlane SV, Zhao L, Staples JF (2017) Regulation of mitochondrial metabolism during hibernation by reversible suppression of electron transport system enzymes. J Comp Physiol B 187:227-34.	LEAK OXPHOS	N S CIV ROX DQ	Intact cells Isolated mitochondria	Other mammals	Liver
Tegelberg 2017 Orphanet J Rare Dis	2017	Tegelberg S, Tomašić N, Kallijärvi J, Purhonen J, Elmér E, Lindberg E, Nord DG, Soller M, Lesko N, Wedell A, Bruhn H, Freyer C, Stranneheim H, Wibom R, Nennesmo I, Wredenberg A, Eklund EA, Fellman V (2017) Respiratory chain complex III deficiency due to mutated BCS1L: a novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model. Orphanet J Rare Dis 12:73.	LEAK ROUTINE OXPHOS ET	N NS ROX S	Permeabilized cells	Human Mouse	Blood cells Platelet
Van den Berg 2017 Am J Respir Crit Care Med	2017	van den Berg M, Hooijman PE, Beishuizen A, de Waard MC, Paul MA, Hartemink KJ, van Hees HWH, Lawlor MW, Brocca L, Bottinelli R, Pellegrino MA, Stienen GJM, Heunks LMA, Wüst RCI, Ottenheijm CAC (2017) Diaphragm atrophy and weakness in the absence of mitochondrial dysfunction in the critically ill. Am J Respir Crit Care Med 196:1544-58.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Khairallah 2017 J Cell Biochem	2017	Khairallah A, Farag AA, Johar D, Bernstein L (2017) Endocrine imbalance associated with proteome changes in diabetes. J Cell Biochem 118:3569-76.		ROX		Human	Platelet Blood cells
Buck 2017 PLOS ONE	2017	Buck E, Zügel M, Schumann U, Merz T, Gumpp AM, Witting A, Steinacker JM, Landwehrmeyer GB, Weydt P, Calzia E, Lindenberg KS (2017) High-resolution respirometry of fine-needle muscle biopsies in pre-manifest Huntington's disease expansion mutation carriers shows normal mitochondrial respiratory function. PLOS ONE 12:e0175248.	LEAK OXPHOS ET	F N S NS ROX	Homogenate	Human Mouse	Heart Skeletal muscle Nervous system Liver
Ramirez 2017 Cell Metab	2017	Ramírez S, Gómez-Valadés AG, Schneeberger M, Varela L, Haddad-Tóvolli R, Altirriba J, Noguera E, Drougard A, Flores-Martínez Á, Imbernón M, Chivite I, Pozo M, Vidal-Itriago A, Garcia A, Cervantes S, Gasa R, Nogueiras R, Gama-Pérez P, Garcia-Roves PM, Cano DA, Knauf C, Servitja JM, Horvath TL, Gomis R, Zorzano A, Claret M (2017) Mitochondrial dynamics mediated by mitofusin 1 is required for POMC neuron glucose-sensing and insulin release control. Cell Metab 25:1390-9.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Mouse	Nervous system
Jeong 2017 Exp Mol Med	2017	Jeong JH, Cheol Kang Y, Piao Y, Kang S, Pak YK (2017) miR-24-mediated knockdown of H2AX damages mitochondria and the insulin signaling pathway. Exp Mol Med 49:e313.	OXPHOS	N S Gp CIV ROX	Permeabilized cells	Human	Liver
Lalia 2017 Aging (Albany NY)	2017	Lalia AZ, Dasari S, Robinson MM, Abid H, Morse DM, Klaus KA, Lanza IR (2017) Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults. Aging (Albany NY) 9:1096-1129.	OXPHOS LEAK ET	F N NS ROX S	Isolated mitochondria	Human	Skeletal muscle
Kane 2017 J Cell Mol Med	2017	Kane MS, Alban J, Desquiret-Dumas V, Gueguen N, Ishak L, Ferre M, Amati-Bonneau P, Procaccio V, Bonneau D, Lenaers G, Reynier P, Chevrollier A (2017) Autophagy controls the pathogenicity of OPA1 mutations in dominant optic atrophy. J Cell Mol Med 21:2284-97.	LEAK ET	Other combinations ROX	Intact cells	Human	Fibroblast
Boutant 2017 EMBO J	2017	Boutant M, Kulkarni SS, Joffraud M, Ratajczak J, Valera-Alberni M, Combe R, Zorzano A, Cantó C (2017) Mfn2 is critical for brown adipose tissue thermogenic function. EMBO J 36:1543-58.	ROUTINE LEAK OXPHOS ET	ROX N S NS	Intact cells Homogenate Isolated mitochondria	Mouse	Fat Fibroblast
Uzhachenko 2017 Aging (Albany NY)	2017	Uzhachenko R, Boyd K, Olivares-Villagomez D, Zhu Y, Goodwin JS, Rana T, Shanker A, Tan WJ, Bondar T, Medzhitov R, Ivanova AV (2017) Mitochondrial protein Fus1/Tusc2 in premature aging and age-related pathologies: critical roles of calcium and energy homeostasis. Aging (Albany NY) 9:627-49.	LEAK ET ROUTINE	ROX	Intact cells	Mouse	Kidney Endothelial;epithelial;mesothelial cell Fibroblast
Dahlke 2017 Glob Chang Biol	2017	Dahlke FT, Leo E, Mark FC, Pörtner HO, Bickmeyer U, Frickenhaus S, Storch D (2017) Effects of ocean acidification increase embryonic sensitivity to thermal extremes in Atlantic cod, Gadus morhua. Glob Chang Biol 23(4):1499-1510.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Fishes
Leo 2017 Front Zool	2017	Leo E, Kunz KL, Schmidt M, Storch D, Portner HO, Mark FC (2017) Mitochondrial acclimation potential to ocean acidification and warming of Polar cod (Boreogadus saida) and Atlantic cod (Gadus morhua). Front Zool 14:21.	LEAK OXPHOS ET	CIV NS ROX	Permeabilized tissue	Fishes	Heart
Cavalcanti-de-Albuquerque 2017 Mol Neurobiol	2017	Cavalcanti-de-Albuquerque JP, de Souza Ferreira E, de Carvalho DP, Galina A (2017) Mitochondria-bound hexokinase (mt-HK) activity differ in cortical and hypothalamic synaptosomes: differential role of mt-HK in H₂O₂ depuration. Mol Neurobiol 55:5889-5900.	LEAK OXPHOS	N S Gp ROX	Intact cells	Rat	Nervous system
Elmer 2017 US Patent	2017	Elmer E, Hansson MJ, Ehinger JK, Piel S, Moss S (2017) Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to complex I-related impairment of mitochondrial oxidative phosphorylation. US Patent US20170100359 A1.	LEAK ROUTINE OXPHOS ET	S ROX	Intact cells	Human	Heart Blood cells Fibroblast Macrophage-derived Platelet
Darrell 2017 US Patent	2017	Neufer PD, Anderson EJ, Szeto HH (2017) Methods for preventing or treating insulin resistance. US Patent US20170100450 A1.	LEAK OXPHOS	F N S ROX	Permeabilized tissue	Human Rat	Skeletal muscle
Rouet 2017 US Patent	2017	Rouet P, Smih F (2017) ApoO for use in method for treating cancer and various pathophysiological situations. US Patent US20170035842 A1.	LEAK ET	ROX	Isolated mitochondria	Human Mouse	Heart Liver
Dallon 2017 Biochem J	2017	Dallon BW, Parker BA, Hodson AE, Tippetts TS, Harrison ME, Appiah MMA, Witt JE, Gibbs JL, Gray HM, Sant TM, Bikman BT (2017) Insulin selectively reduces mitochondrial uncoupling in brown adipose tissue in mice. Biochem J 475:561-9.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle Fat
Klosterhoff 2017 Int J Biol Macromol	2017	Klosterhoff RR, Kanazawa LKS, Furlanetto ALDM, Peixoto JVC, Corso CR, Adami ER, Iacomini M, Fogaça RTH, Acco A, Cadena SMSC, Andreatini R, Cordeiro LMC (2017) Anti-fatigue activity of an arabinan-rich pectin from acerola (Malpighia emarginata). Int J Biol Macromol 109:1147-53.	OXPHOS	N ROX	Permeabilized tissue	Mouse	Skeletal muscle
Galambo 2017 Thesis	2017	Galambo D (2017) The effect of cardiolipin on vascular smooth muscle cell dedifferentiation, function, and mitochondrial respiration. Master's Thesis p.90.	LEAK OXPHOS	F N CIV NS ROX	Permeabilized tissue	Mouse	Endothelial;epithelial;mesothelial cell
Schaefer 2017 Neurophotonics	2017	Schaefer PM, Hilpert D, Niederschweiberer M, Neuhauser L, Kalinina S, Calzia E, Rueck A, von Einem B, von Arnim CAF (2017) Mitochondrial matrix pH as a decisive factor in neurometabolic imaging. Neurophotonics 4:045004.	ROUTINE ET	CIV ROX			Kidney HEK
Lau 2017 Dissertation	2017	Lau G (2017) Adaptive variation of mitochondrial function in response to oxygen variability in intertidal sculpins (Cottidae, Actinopterygii). Dissertation p148.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Fishes	Nervous system
Yan 2017 BMC Genomics	2017	Yan X, Eynon N, Papadimitriou ID, Kuang J, Munson F, Tirosh O, O’Keefe L, Griffiths LR, Ashton KJ, Byrne N, Pitsiladis YP, Bishop DJ (2017) The gene SMART study: method, study design, and preliminary findings. BMC Genomics 18:821.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Scrima 2017 PLOS ONE	2017	Scrima R, Menga M, Pacelli C, Agriesti F, Cela O, Piccoli C, Cotoia A, De Gregorio A, Gefter JV, Cinnella G, Capitanio N (2017) Para-hydroxyphenylpyruvate inhibits the pro-inflammatory stimulation of macrophage preventing LPS-mediated nitro-oxidative unbalance and immunometabolic shift. PLOS ONE 12:e0188683.	LEAK ROUTINE ET	ROX	Intact cells	Human Mouse	Endothelial;epithelial;mesothelial cell Blood cells Fibroblast Macrophage-derived
Radenkovic 2017 Biochem Pharmacol	2017	Radenkovic F, Holland OJ, Vanderlelie JJ, Perkins AV (2017) Selective inhibition of endogenous antioxidants with Auranofin causes mitochondrial oxidative stress which can be countered by selenium supplementation. Biochem Pharmacol 146:42-52.	ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Human	Other cell lines
Bansal 2017 Environ Health Perspect	2017	Bansal A, Rashid C, Xin F, Li C, Polyak E, Duemler A, van der Meer T, Stefaniak M, Wajid S, Doliba N, Bartolomei MS, Simmons RA (2017) Sex- and dose-specific effects of maternal bisphenol A exposure on pancreatic islets of first- and second-generation adult mice offspring. Environ Health Perspect 125:097022.	LEAK ROUTINE ET	ROX	Intact cells	Mouse	Islet cell;pancreas;thymus
Xu 2017 Diabetes	2017	Xu D, Xu S, Kyaw AMM, Lim YC, Chia SY, Chee Siang DT, Alvarez-Dominguez JR, Chen P, Leow MK, Sun L (2017) RNA binding protein Ybx2 regulates RNA stability during cold-induced brown fat activation. Diabetes 66:2987-3000.	LEAK OXPHOS ET	N ROX		Mouse	Skeletal muscle
Geoghegan 2017 Oncol Lett	2017	Geoghegan F, Chadderton N, Farrar GJ, Zisterer DM1, Porter RK (2017) Direct effects of phenformin on metabolism/bioenergetics and viability of SH-SY5Y neuroblastoma cells. Oncol Lett 14:6298-306.		N NS ROX	Permeabilized cells	Human	Nervous system
Goedecke 2017 JMIR Res Protoc	2017	Goedecke JH, Mendham AE, Clamp L, Nono Nankam PA, Fortuin-de Smidt MC, Phiri L, Micklesfield LK, Keswell D, Woudberg NJ, Lecour S, Alhamud A, Kaba M, Lutomia FM, van Jaarsveld PJ, de Villiers A, Kahn SE, Chorell E, Hauksson J, Olsson T (2017) An exercise intervention to unravel the mechanisms underlying insulin resistance in a cohort of black South African women: Protocol for a randomized controlled trial. JMIR Res Protoc 03/10/2017:9098.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle Fat
Cockova 2017 Thesis	2017	Čočková Z (2017) Modulation of RNA demethylase FTO function in SH-SY5Y cells: the effect on insulin signaling and mitochondrial respiration. Diploma Thesis p70.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells Isolated mitochondria	Human	Nervous system
Fourcade 2017 Aging Cell	2017	Fourcade S, Morató L, Parameswaran J, Ruiz M, Ruiz-Cortés T, Jové M, Naudí A, Martínez-Redondo P, Dierssen M, Ferrer I, Villarroya F, Pamplona R, Vaquero A, Portero-Otín M, Pujol A (2017) Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance. Aging Cell 16:1404-13.	LEAK OXPHOS	N S NS ROX		Mouse
Ho 2017 Thesis	2017	Ho DH (2017) The role of MLQ protein in structure and function of mammalian ATP synthase. Master's Thesis p84.	LEAK OXPHOS ET	N S CIV NS ROX	Intact cells Permeabilized cells	Human	Kidney
Martins 2017 Thesis	2017	Martins WC (2017) Estudo do efeito protetor da atorvastatina e dos eventos iniciais da neurotoxicidade induzida pelo peptídeo β-amilóide (Aβ1-40) em camundongos. Doctoral Thesis p85.	LEAK OXPHOS ET	N NS ROX	Homogenate	Mouse	Nervous system
Victor 2017 Thesis	2017	Victor L (2017) Investigating the possible cytoprotective effects of melatonin isomer against simulated ischemic injury. Master's Thesis 76.	LEAK OXPHOS ET	N CIV NS ROX	Permeabilized cells	Rat	Fibroblast
Wetzel 2017 Thesis	2017	Wetzel MD (2017) Mechanism of metformin action in dermal fibroblasts. PhD Thesis 125.	LEAK OXPHOS	F N NS ROX	Intact cells	Human	Fibroblast
Categories of SUIT protocols	2017	Gnaiger E (2017) Categories of SUIT protocols and ETS pathway control states. MiPNet 2017-03-12; original 2016-03-20; edited 2016-08-21.		F N S Gp CIV NS Other combinations ROX
Westerlund 2017 Pediatr Res	2017	Westerlund E, Marelsson SE, Ehinger JK, Sjövall F, Morota S, Åsander Frostner E, Oldfors A, Darin N, Lundgren J, Hansson MJ, Fellman V, Elmér E (2017) Oxygen consumption in platelets as an adjunct diagnostic method for pediatric mitochondrial disease. Pediatr Res 83:455-65.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Platelet Blood cells
Porplycia 2017 Am J Physiol Regul Integr Comp Physiol	2017	Porplycia D, Lau GY, McDonald J, Chen Z, Richards JG, Moyes CD (2017) Subfunctionalization of COX4 paralogs in fish. Am J Physiol Regul Integr Comp Physiol 312:R671-R680.	LEAK	CIV ROX	Isolated mitochondria	Fishes	Skeletal muscle
Huang 2017 Sci Rep	2017	Huang L, Zhang K, Guo Y, Huang F, Yang K, Chen L, Huang K, Zhang F, Long Q, Yang Q (2017) Honokiol protects against doxorubicin cardiotoxicity via improving mitochondrial function in mouse hearts. Sci Rep 7:11989.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Mouse	Heart
Rohde 2017 Cell Death Differ	2017	Rohde K, Kleinesudeik L, Roesler S, Löwe O, Heidler J, Schröder K, Wittig I, Dröse S, Fulda S (2017) A Bak-dependent mitochondrial amplification step contributes to Smac mimetic/glucocorticoid-induced necroptosis. Cell Death Differ 24:83-97.	LEAK ROUTINE ET	CIV ROX	Intact cells	Mouse	Fibroblast
Fisar 2017 Indian J Biochem Biophys	2017	Fišar Z, Hroudová J, Namrata S, Macečková D, Kopřivová A (2017) Protocols for high-resolution respirometry experiments to test the activity of electron transfer system of pig brain mitochondria. Indian J Biochem Biophys 54:258-72.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Pig	Nervous system
Pfeiffer 2017 Free Radic Biol Med	2017	Pfeiffer A, Schneider J, Bueno D, Dolga A, Voss TD, Lewerenz J, Wüllner V, Methner A (2017) Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity. Free Radic Biol Med 112:350-9.	LEAK ROUTINE OXPHOS ET	N NS ROX	Permeabilized cells	Mouse	Fibroblast
Xhani 2017 Thesis	2017	Xhani M (2017) Cellular redox homeostasis and environmental toxicity. Dissertation p110.	OXPHOS	N S CIV ROX	Permeabilized cells	Human	Liver Other cell lines
Schaefer 2017 Thesis	2017	Schaefer P (2017) Metabolic imaging in Alzheimer´s disease using NADH autofluorescence. Dissertation p93.	LEAK ET ROUTINE	CIV ROX	Intact cells	Human	HEK Other cell lines
Cervoni 2017 J Exp Biol	2017	Cervoni MS, Cardoso-Júnior CAM, Craveiro G, Souza AO, Alberici LC, Hartfelder K (2017) Mitochondrial capacity, oxidative damage and hypoxia gene expression are associated with age-related division of labor in honey bee (Apis mellifera L.) workers. J Exp Biol 220:4035-46.	LEAK ROUTINE OXPHOS ET	N ROX	Intact cells

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