Loew 1961 Biochem Biophys Res Commun

Loew H, Krueger H, Ziegler DM (1961) On the reduction of externally added DPN by succinate in submitochondrial particles. Biochem Biophys Res Commun 5:231-7.

» PMID: 13763797

Loew H, Krueger H, Ziegler DM (1961) Biochem Biophys Res Commun

Abstract: It has recently been reported from several laboratories that mitochondrial DPN is reduced by succinate and that this reduction requires the addition of ATP. All of these studies involved intact mitochondria and bound DPN.

In the present communication some experiments will be described which deal with the reduction of added DPN by a submitochondrial particle from beef heart muscle, ETPH. This particle enjoys several advantages for the study of DPN reduction; it contains little or no bound DPN, and does not have a functional Krebs cycle (which excludes any reduction of DPN by substrates other than succinate). • Keywords: DPN, succinate, ATP, ETPH

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Organism: Bovines  Tissue;cell: Heart  Preparation: Isolated mitochondria  Enzyme: Complex II;succinate dehydrogenase  Regulation: ATP 

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