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Difference between revisions of "CH Basel Kraehenbuehl S"

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|country=Switzerland
|country=Switzerland
|Contact=Kraehenbuehl Stephan
|Contact=Kraehenbuehl Stephan
|MiPNetLab=Calame Martine, Hirzel Estelle, Bouitbir Jamal
|MiPNetLab=Bouitbir Jamal, Calame Martine, Haegler Patrizia, Hirzel Estelle, Panajatovic Miljenko,
|Team previous=Lindinger Peter W, Felser Andrea
|Team previous=Felser Andrea, Lindinger Peter W, Singh Francois,
|Status=[[Power-O2k|''' 2 Power-O2k''']] 2010-
|Status=[[Power-O2k|''' 3 Power-O2k''']] 2010-
|info=[[MiP2014]], [[IOC75]], [[IOC68]], [[IOC60]]
|info=[[IOC124]], [[MiP2014]], [[IOC75]], [[IOC68]], [[IOC60]]
}}
}}
[[Category:Power-O2k]]
[[Category:Power-O2k]]

Latest revision as of 08:30, 2 May 2018

                



CH Basel Kraehenbuehl S

Oroboros O2k-Network

O2k-Network
O2k-Network Lab UniversitÀtsspital Basel

Department Biomedizin

Labor 410, Klinische Pharmakologie und Toxikologie

Address Hebelstrasse 20, 4031
City Basel
State/Prov
Country Switzerland
Weblink
Contact Kraehenbuehl Stephan
Team Bouitbir Jamal, Calame Martine, Haegler Patrizia, Hirzel Estelle, Panajatovic Miljenko
Team previous Felser Andrea, Lindinger Peter W, Singh Francois
Status 3 Power-O2k 2010-
Oroboros Events IOC124, MiP2014, IOC75, IOC68, IOC60
Topics


O2k-Publications

 PublishedReference
Abegg 2024 Toxicol Lett2024Abegg VF, Panajatovic MV, Mancuso RV, Allard JA, Duthaler U, Odermatt A, KrĂ€henbĂŒhl S, Bouitbir J (2024) Mechanisms of hepatocellular toxicity associated with the components of St. John's Wort extract hypericin and hyperforin in HepG2 and HepaRG cells. https://doi.org/10.1016/j.toxlet.2024.01.008
Bouitbir 2022 Int J Mol Sci2022Bouitbir J, Panajatovic MV, KrĂ€henbĂŒhl S (2022) Mitochondrial toxicity associated with imatinib and sorafenib in isolated rat heart fibers and the cardiomyoblast H9c2 cell line. Int J Mol Sci 23:2282. https://doi.org/10.3390/ijms23042282
Gruenig 2020 Biochem Pharmacol2020GrĂŒnig D, Szabo L, Marbet M, KrĂ€henbĂŒhl S (2020) Valproic acid affects fatty acid and triglyceride metabolism in HepaRG cells exposed to fatty acids by different mechanisms. Biochem Pharmacol 177:113860.
Zhou 2019 Int J Mol Sci2019Zhou X, Luethi D, Sanvee GM, Bouitbir J, Liechti ME, KrĂ€henbĂŒhl S (2019) Molecular toxicological mechanisms of synthetic cathinones on C2C12 myoblasts. Int J Mol Sci 20:E1561.
Bouitbir 2019 Toxicology2019Bouitbir J, Alshaikhali A, Panajatovic MV, Abegg VF, Paech F, KrĂ€henbĂŒhl S (2019) Mitochondrial oxidative stress plays a critical role in the cardiotoxicity of sunitinib. Toxicology 426:152281.
Paech 2018a Toxicology2018Paech F, Mingard C, GrĂŒnig D, Abegg VF, Bouitbir J, KrĂ€henbĂŒhl S (2018) Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells. Toxicology 395:34-44.
Paech 2018b Toxicology2018Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, KrĂ€henbĂŒhl S (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology 409:13-23.
Singh 2018 Arch Toxicol2018Singh F, Zoll J, Duthaler U, Charles AL, Panajatovic MV, Laverny G, McWilliams TG, Metzger D, Geny B, KrĂ€henbĂŒhl S, Bouitbir J (2018) PGC-1ÎČ modulates statin-associated myotoxicity in mice. Arch Toxicol 93:487-504.
Haegler 2017 PLOS ONE2017Haegler P, GrĂŒnig D, Berger B, Terracciano L, KrĂ€henbĂŒhl S, Bouitbir J (2017) Hepatic effects of pharmacological doses of hydroxy-cobalamin[c-lactam] in mice. PLOS ONE 12:e0171026.
Gruenig 2017 Toxicol In Vitro2017GrĂŒnig D, Felser A, Bouitbir J, KrĂ€henbĂŒhl S (2017) The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells. Toxicol In Vitro 42:337-47.
Paech 2017 Arch Toxicol2017Paech F, Messner S, Spickermann J, Wind M, Schmitt-Hoffmann AH, Witschi AT, Howell BA, Church RJ, Woodhead J, Engelhardt M, KrĂ€henbĂŒhl S, Maurer M (2017) Mechanisms of hepatotoxicity associated with the monocyclic ÎČ-lactam antibiotic BAL30072. Arch Toxicol 91:3647-62.
Luethi 2017 Toxicology2017Luethi D, Liechti ME, KrĂ€henbĂŒhl S (2017) Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones. Toxicology 387:57-66.
Brecht 2016 Toxicol In Vitro2016Brecht K, Riebel V, Couttet P, Paech F, Wolf A, Chibout SD, Pognan F, KrĂ€henbĂŒhl S, Uteng M (2016) Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin. Toxicol In Vitro 40:55-65.
Bouitbir 2016 Antioxid Redox Signal2016Bouitbir J, Singh F, Charles AL, Schlagowski AI, Bonifacio A, Echaniz-Laguna A, Geny B, KrĂ€henbĂŒhl S, Zoll J (2016) Statins trigger mitochondrial ROS-induced apoptosis in glycolytic skeletal muscle. Antioxid Redox Signal 24:84-98.
Bonifacio 2016 Arch Toxicol2016Bonifacio A, Mullen PJ, Mityko IS, Navegantes LC, Bouitbir J, KrĂ€henbĂŒhl S (2016) Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo. Arch Toxicol 90:203-15. doi: 10.1007/s00204-014-1378-4
Bratic 2016 PLoS Genet2016Bratic A, Clemente P, Calvo-Garrido J, Maffezzini C, Felser A, Wibom R, Wedell A, Freyer C, Wredenberg A (2016) Mitochondrial polyadenylation is a one-step process required for mRNA integrity and tRNA maturation. PLoS Genet 12:e1006028.
Singh 2015 Biochim Biophys Acta2015Singh F, Charles AL, Schlagowski AI, Bouitbir J, Bonifacio A, Piquard F, KrĂ€henbĂŒhl S, Geny B, Zoll J (2015) Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesis. Biochim Biophys Acta 1853:1574-85.
Haegler 2015 Toxicology2015Haegler P, GrĂŒnig D, Berger B, KrĂ€henbĂŒhl S, Bouitbir J (2015) Impaired mitochondrial function in HepG2 cells treated with hydroxy-cobalamin[c-lactam]: A cell model for idiosyncratic toxicity. Toxicology 336:48-58.
Felser 2014 Toxicology I2014Felser A, Stoller A, Morand R, Schnell D, Donzelli M, Terracciano L, Bouitbir J, KrĂ€henbĂŒhl S (2014) Hepatic toxicity of dronedarone in mice: role of mitochondrial ÎČ-oxidation. Toxicology 323:1-9.
Morand 2014 Eur J Nutr2014Morand R, Bouitbir J, Felser A, Hench J, Handschin C, Frank S, KrĂ€henbĂŒhl S (2014) Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice. Eur J Nutr 53:1313-25.
Felser 2014 Toxicology II2014Felser A, Lindinger PW, Schnell D, Kratschmar DV, Odermatt A, Mies S, Jenö P, KrĂ€henbĂŒhl S (2014) Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. Toxicology 324:136-46.
Hirzel 2014 PhD Thesis2014Hirzel E (2014) Characterization of human bone marrow derived mesenchymal stem cells as a model for in vitro adipocytes studies. PhD Thesis 1-106.
Felser 2013 Toxicol Sci2013Felser A, Blum K, Lindinger PW, Bouitbir J, Kraehenbuehl S (2013) Mechanisms of hepatocellular toxicity associated with dronedarone - a comparison to amiodarone. Toxicol Sci 131:480-90.
Hirzel 2013 J Recept Signal Transduct Res2013Hirzel E, Lindinger PW, Maseneni S, Giese M, Rhein VV, Eckert A, Hoch M, KrĂ€henbĂŒhl S, Eberle AN (2013) Differential modulation of ROS signals and other mitochondrial parameters by the antioxidants MitoQ, resveratrol and curcumin in human adipocytes. J Recept Signal Transduct Res 33:304-12.

O2k-Abstracts

 PublishedReference
Panajatovic 2017 IOC1242017Role of PGC-1α associated mitochondrial biogenesis in statin-induced myotoxicity.
Bouitbir 2012 Abstract IOC682012Bouitbir J, Charles A-L, Echaniz-Laguna A, Kindo M, Daussin F, Auwerx J, Piquard F, Geny B, Zoll J (2012) Effects of statins on mitochondrial function in cardiac and skeletal muscles. MiPNet17.08.