- high-resolution terminology - matching measurements at high-resolution
NS-pathway control state
Description
[[Description::The Complex I&II-linked substrate state is induced in mt-preparations by addition of NADH-generating substrates (CI-linked) in combination with succinate (CII-linked). This physiological substrate combination is required for partial reconstiturion of TCA cycle function and convergent electron-input into the Q-junction to compensate for metabolite depletion into the incubation medium. An Additive effect of convergent CI&II electron flow is observed in most types of mitochondria.]]
Abbreviation: CI&II-linked
Reference: [[Info::Gnaiger 2014 MitoPathways]]
MitoPedia concepts:
Respiratory state
MitoPedia O2k and high-resolution respirometry: SUIT state
MitoPedia topics:
Substrate and metabolite
