Miller 2006 FEBS Lett: Difference between revisions
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|tissues=Hepatocyte; Liver | |tissues=Hepatocyte; Liver | ||
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|discipline=Biomedicine | |discipline=Biomedicine | ||
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Revision as of 18:29, 7 December 2012
| Miller I, Gemeiner M, Gesslbauer B, Kungl A, Piskernik C, Haindl S, NΓΌrnberger S, Bahrami S, Redl H, Kozlov AV (2006) Proteome analysis of rat liver mitochondria reveals a possible compensatory response to endotoxic shock. FEBS Let 580: 1257-1262. |
Β» [[Has info::PMID: 16442530]]
Miller I, Gemeiner M, Gesslbauer B, Kungl A, Piskernik C, Haindl S, Nuernberger S, Bahrami S, Redl H, Kozlov AV (2006) FEBS Let
Abstract: [[has abstract::Organ failure induced by endotoxic shock has recently been associated with affected mitochondrial function. In this study, effects of in vivo lipopolysaccharide-challenge on protein patterns of rat liver mitochondria in treated animals versus controls were studied by two-dimensional electrophoresis (differential image gel electrophoresis). Significant upregulation was found for ATP-synthase Ξ± chain and superoxide dismutase [Mn]. Our data suggest that endotoxic shock mediated changes in the mitochondrial proteome contribute to a compensatory reaction (adaptation to endotoxic shock) rather than to a mechanism of cell damage.]] β’ Keywords: Mitochondria, Proteomics, Lipopolysaccharide, Endotoxic shock, ATP-synthase, Superoxide dismutase
β’ O2k-Network Lab: AT_Vienna_Kozlov AV
Labels:
Stress:Mitochondrial Disease; Degenerative Disease and Defect Organism: Rat Tissue;cell: Hepatocyte; Liver
Coupling state: OXPHOS
HRR: Oxygraph-2k
