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Szabadkai Gyorgy

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


Szabadkai Gyorgy


MitoPedia topics: EAGLE 

COST: Member

COST WG2: WG2


Name Szabadkai Gyorgy, MD, PhD

Senior Lecturer

Institution Department of Cell and Developmental Biology

Consortium for Mitochondrial Research (CfMR)

University College London

Address Gower Street, WC1E 6BT
City London
State/Province
Country United Kingdom
Email [email protected]
Weblink
O2k-Network Lab


Labels: Field of research: Basic 



Publications

 PublishedReference
Menegollo 2019 Methods Mol Biol2019Menegollo M, Tessari I, Bubacco L, Szabadkai G (2019) Determination of ATP, ADP, and AMP Levels by Reversed-Phase High-Performance Liquid Chromatography in Cultured Cells. Methods Mol Biol 1925:223-32.
Briston 2017 Sci Rep2017Briston T, Roberts M, Lewis S, Powney B, M Staddon J, Szabadkai G, Duchen MR (2017) Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability. Sci Rep 7:10492.
Selwood 2017 US Patent2017Selwood DL, Baker D, Szabadkai G, Duchen MR, Hill JM, Warne JND (2017) Quinolium conjugates of cyclosporin. US Patent US20170349632 A1.
Briston 2016 Sci Rep2016Briston T, Lewis S, Koglin M, Mistry K, Shen Y, Hartopp N, Katsumata R, Fukumoto H, Duchen MR, Szabadkai G, Staddon JM, Roberts M, Powney B (2016) Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep 6:37798.
Warne 2015 J Biol Chem2015Warne J, Pryce G, Hill JM, Shi X, Lennerรฅs F, Puentes F, Kip M, Hilditch L, Walker P, Simone MI, Chan AWE, Towers GJ, Coker AR, Duchen MR, Szabadkai G, Baker D, Selwood DL (2015) Selective inhibition of the mitochondrial permeability transition pore protects against neuro-degeneration in experimental multiple sclerosis. J Biol Chem 291:4356-73.
Logan 2014 Nat Genet2014Logan CV, Szabadkai G, Sharpe JA, Parry DA, Torelli S, Childs AM, Kriek M, Phadke R, Johnson CA, Roberts NY, Bonthron DT, Pysden KA, Whyte T, Munteanu I, Foley AR, Wheway G, Szymanska K, Natarajan S, Abdelhamed ZA, Morgan JE, Roper H, Santen GW, Niks EH, van der Pol WL, Lindhout D, Raffaello A, De Stefani D, den Dunnen JT, Sun Y, Ginjaar I, Sewry CA, Hurles M, Rizzuto R. UK10K Consortium, Duchen MR, Muntoni F, Sheridan E (2014) Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. Nat Genet 46:188-93.
Astin 2013 Sci Rep2013Astin R, Bentham R, Djafarzadeh S, Horscroft JA, Kuc RE, Leung PS, Skipworth JR, Vicencio JM, Davenport AP, Murray AJ, Takala J, Jakob SM, Montgomery H, Szabadkai G (2013) No evidence for a local renin-angiotensin system in liver mitochondria. Sci Rep 3:2467.

Abstracts

 PublishedReference
Logan 2015 Abstract MiPschool London 20152015Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signalling.
Hill 2015 Abstract MiPschool London 20152015A novel inhibitor of the mitochondrial permeability transition pore is beneficial in an experimental model of multiple sclerosis.
Matteo 2015 Abstract MiPschool London 20152015Mitochondrial and nuclear IP3-mediated Ca2+ signaling in core myopathies.
Bentham 2015 Abstract MiPschool London 20152015Specific mitochondrial biogenesis patterns underlie development of breast cancer subtypes.
Duchen 2012 Abstract Bioblast2012Blacker TS, Gale JE, Ziegler M, Bain AJ, Szabadkai G, Duchen MR (2012) Separation of NADPH and NADH fluorescence emission in live cells using fluorescence lifetime imaging microscopy. Mitochondr Physiol Network 17.12.


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