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Spinazzi Marco

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


Spinazzi Marco


MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1


Name Spinazzi Marco, MD, PhD
Institution
Spinazzi Marco
Ingénieur hospitalier

Biochimie Métabolique et Hormonologie

Département de Biochimie et Génétique

Address IBS - CHU Angers

BNVI CNRS 6214 / INSERM U771

02.41.35.77.04,

City Angers
State/Province
Country France
Email [email protected]
Weblink
O2k-Network Lab BE Leuven Spinazzi M, FR Angers Gueguen N

Bioenergetics Communications

Keywords: mitochondria, neurodegeneration, neurological disorders, brain, muscle

MitoEAGLE

        • Benefits for COST and for the COST Action MitoEAGLE
I believe it will be a very useful contribution if we’ll be able to finalize in a next future a consensus paper on mitochondrial function terminology as we discussed.

Participated at

Visiting scientist in the Oroboros O2k-Laboratory

O2k-Network

Marco Spinazzi: Visiting scientist at the Oroboros O2k-Laboratory

  • October 21 to October 22 2015


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Publications

 PublishedReference
Radaelli 2023 Elife2023Radaelli E, Assenmacher CA, Verrelle J, Banerjee E, Manero F, Khiati S, Girona A, Lopez-Lluch G, Navas P, Spinazzi M (2023) Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis. https://doi.org/10.7554/elife.84710
Cornelissen 2020 Hum Mol Genet2020Cornelissen T, Spinazzi M, Martin S, Imberechts D, Vangheluwe P, Bird M, De Strooper B, Vandenberghe W (2020) CHCHD2 harboring the Parkinson's disease-linked T61I mutation precipitates inside mitochondria and induces precipitation of wild-type CHCHD2. Hum Mol Genet 29:1096-106.
Kanellopoulos 2020 Cell2020Kanellopoulos AK, Mariano V, Spinazzi M, Woo YJ, McLean C, Pech U, Li KW, Armstrong JD, Giangrande A, Callaerts P, Smit AB, Abrahams BS, Fiala A, Achsel T, Bagni C (2020) Aralar sequesters GABA into hyperactive mitochondria, causing social behavior deficits. Cell 180:1178-97.
BEC 2020.1 doi10.26124bec2020-0001.v12020Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Spinazzi 2019 Proc Natl Acad Sci U S A2019Spinazzi M, Radaelli E, Horré K, Arranz AM, Gounko NV, Agostinis P, Maia TM, Impens F, Morais VA, Lopez-Lluch G, Serneels L, Navas P, De Strooper B (2019) PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome. Proc Natl Acad Sci U S A 116:277-86.
Leucci 2016 Nature2016Leucci E, Vendramin R, Spinazzi M, Laurette P, Fiers M, Wouters J, Radaelli E, Eyckerman S, Leonelli C, Vanderheyden K, Rogiers A, Hermans E, Baatsen P, Aerts S, Amant F, Van Aelst S, van den Oord J, de Strooper B, Davidson I, Lafontaine DL, Gevaert K, Vandesompele J, Mestdagh P, Marine JC (2016) Melanoma addiction to the long non-coding RNA SAMMSON. Nature 531:518-22.
Spinazzi 2014 Neuropathol Appl Neurobiol2014Spinazzi M, Sghirlanzoni A, Salviati L, Angelini C (2014) Impaired copper and iron metabolism in blood cells and muscles of patients affected by copper deficiency myeloneuropathy. Neuropathol Appl Neurobiol 40:888-98.
Spinazzi 2012 Nat Protoc2012Spinazzi M, Casarin A, Pertegato V, Salviati L, Angelini C (2012) Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells. Nat Protoc 7:1235-46.

Abstracts

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