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MiPschool Tromso-Bergen 2018

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MiPschool Tromso-Bergen 2018

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Tromso-Bergen, NO. 2018 Oct 20-24, 11th MitoEAGLE Training School - MiPschool 2018. From basics of mitochondrial physiology to cardiovascular health and disease.

» Mitochondrial Physiology Society

Mitochondrial Physiology Society (2018-10-20) MitoGlobal

Abstract: MiPschool, Tromso-Bergen, Norway 2018

University of Tromsø
He lead the way - Leiv Eiriksson

MiPschool 2018 group.jpg

Impressions MiPschool Tromso-Bergen 2018

Feedback

The evaluation of the present and previous training schools will be integrated into the programme of the MitoEAGLE/MiPschool 2019 in Coimbra, PT:
  1. Abstracts selected for oral presentations (10+5 min) are retained - training for conference presentations with critical discussions.
  2. Meet the expert sessions are emphasized - training in small groups, discussions on a large variety of topics.
  3. Introductory lectures are extended, replacing conference-style presentations by invited lecturers. Three specific topics are introduced in detail:
(a) reproducibility of sample preparations;
(b) concepts of respirometric SUIT protocols;
(c) interpretation of results.
An entrance test will be the basis for providing grants to students.
Delegates feedback comments
  • I enjoyed the training school in Norway. The presentations were very nice and the location was remarkable. I have never been to a workshop or conference like this. Very unique for me. - Zobalova Renata
  • I would like to acknowledge the organizers for such a good programme. In addition, the proximity between researchers was very high. Everyone would talk about good science. I met real nice people with different interests at this point
  • MIPschool at a very special location, very much worth doing it again
Delegates feedback for future Training Schools
  • One of the questions raised during the round table was about the physiological consequences of mitochondrial dysfunction at the level of tissues and organisms. I think that this question is very important and that there should be a session aimed at summarizing the current knowledge about it and to develop common and standardized strategies to improve it.
  • I would definitely like to have disruptive works in different organs/systems. Mitochondria is such a complex subject that can go beyond the molecular part. Translational discussion should be more encouraged towards future applications. Finally, writing/grants/career paths could be added.
  • Maybe an poster session should be interesting

Local organizer

Terje Larsen
Larsen Terje
Faculty of Health Sciences, University of Tromsø


Lecturers

Meet the expert

Programme

Programme structure

Topic
Check-in will take place on Saturday, October 20 from 21:00-23:30 pm at Skarven Bar downtown Tromsø, and on the Coastal Express on Sunday from 00:15-01:30 am.
The scientific sessions consist of introductory lectures, selected abstract presentations, and discussions in small groups in an open “meet the expert” format.
  • Sessions E1 - E3: Meet the expert - open MitoEAGLE topics - MitoEAGLE Early Career Investigator Forum
11 senior scientists will be available for discussions in small groups of about 6, dispersed on separate tables, without slide projection (but with paper and pencil). All participants can 'book' mentors in advance, and rotate after 20-30 min to another booked table. The topics are open, with some 'titles' mentioned in the programme. Students may raise the topic of their abstract for discussion, without formal presentation (you may bring along some printed material or A4-size copy of a poster). Mentors may join to form slightly enlarged groups as appropriate.
  • Session E4 – Open programme lectures: Programme decisions made during and by the MitoEAGLE/MiPschool
The Early Career Investigators (ECIs) will shape the programme for Session E4. The options range from topics selected for a round-table discussion, extended elaboration of any topic covered in the programme, selected summaries of Sessions E1 - E3, continuation of 'Meet the expert' sessions, parallel working group meetings on a list of selected topics, or other great ideas on which our ECIs will take a group decision.
Participants joined among the >460 coauthors
  • MitoEAGLE preprint on Mitochondrial respiratory states and rates (Last update 2018-10-25, Version 45) - »Bioblast link«
  • A hardcopy of Version 44 (40 pp.) was handed out at registration. Participants were invited to join as a coauthors during the MitoEAGLE/MiPschool.

Sessions with abstracts for oral presentations

   (Attendance list)
» Final programme for download 

MiPschool programme Sunday, October 21 – Morning

 A1. Mitochondrial physiology: pathways and couplingSession
Gnaiger 2018 MiPschool Tromso A1
Erich Gnaiger
Mitochondrial states and rates: 1. Electron transfer pathways and respiratory control. 2. Coupling control.
Oral
A1


 B1. Energy transfer and movement of molecules in cardiomyocytesSession
Schlattner 2018 MiPschool Tromso B1
Uwe Schlattner
Mitochondrial kinases: key players in respiratory control and energy transfer.
B1
Oral
Vendelin 2018 MiPschool Tromso B1
Marko Vendelin
Restrictions to intracellular diffusion of ATP and ADP in cardiomyocytes.
B1
Oral


MiPschool programme Sunday, October 21 – Afternoon

 C1. Selected abstracts: Cardiac OXPHOSSession
Pereira 2018 MiPschool Tromso C1
Pereira Susana P
Obesity-induced mitochondrial hepatic changes during pregnancy.
Oral
C1
Goncalo Teixeira 2018 MiPschool Tromso C1
MiPsociety
Subchronic in vivo study for the evaluation of hepatic mitochondrial toxicity induced by silver nanoparticles.
Oral
C1
Ma 2018 MiPschool Tromso C1
MiPsociety
Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis.
C1
Oral


 C2. Selected abstracts: CardioprotectionSession
Kampa 2018 MiPschool Tromso C2
Rafal Kampa
Cardioprotective flavoniods as a natural modulators of mitoBKCa channel.
C2
Oral
MartinsJD 2018 MiPschool Tromso C2
MiPsociety
Sweetheart: Cardiac consequences of fetal exposure to maternal gestational diabetes on the offspring mitochondrial function.
C2
Oral
Tuncay 2018 MiPschool Tromso C2
MiPsociety
MitoTEMPO ameliorates hyperglycemia induced mitochondrial damage in cardiomyocytes.
C2
Oral
Jansen 2018 MiPschool Tromso C2
MiPsociety
Dietary and pharmacological treatment of diet-induced obese mice – impact on mitochondrial function.
C2
Oral


MiPschool programme Monday, October 22 – Morning

 D1. Cardiovascular disease and mitochondrial medicineSession
Harper 2018 MiPschool Tromso D1
Mary-Ellen Harper
OXPHOS efficiency in skeletal and cardiac muscles: Proton leaks, ROS and glutathione redox.
D1
Oral
Hoppel 2018 MiPschool Tromso D1
Charles Hoppel
Two populations of muscle mitochondria: heart and skeletal muscle.
D1
Oral


 E1. MitoEAGLE Early Career Investigator ForumSession
Wiesner 2018 MiPschool Tromso E1
MiPsociety
Aging-related accumulation of mitochondrial DNA deletions in skeletal muscle occurs preferentially in Type IIb fibers – high mitophagic flux protects Type I fibers.
E1
Harper 2018 MiPschool Tromso E1
Mary-Ellen Harper
Deacetylation acceleration of BAT thermogenesis.
E1
Iglesias-Gonzalez 2018 MiPschool Tromso E1 Oscillations in mitochondrial ROS production during the early cell cycles in Xenopus embryos.E1
Makrecka-Kuka 2018 MiPschool Tromso E1
Marina Makrecka-Kuka
Cardiac fatty acid oxidation: from in vitro to in vivo.
E1
Murray 2018 MiPschool Tromso E1
Andrew Murray
OXPHOS protocols: understanding the patterns.
E1
Vendelin 2018 MiPschool Tromso E1
Marko Vendelin
Introducing a platform for primary kinetics data analysis.
E1


 E2. MitoEAGLE Early Career Investigator Forum - table discussionsSession
Li Puma 2018 MiPschool Tromso E2
MiPsociety
Fads2 exacerbates myocardial ischemia-reperfusion injury in mice: role of mitochondria.
E2
Siewiera 2018 MiPschool Tromso E2
Karolina Siewiera
Effect of metformin treatment on blood platelet bioenergetics and platelet function in STZ-diabetic and non-diabetic rats.
E2
Alves 2018 MiPschool Tromso E2
MiPsociety
Role for mitochondria on the response of highly proliferative and invasive bladder cancer cells to the combined inhibition of mTOR and SIRT1.
E2
Krajcova 2018 MiPschool Tromso E2
Adela Krajcova
High-resolution respirometry to assess function of mitochondria in native homogenates of human heart muscle.
E2
MartinsAD 2018 MiPschool Tromso E2
MiPsociety
Mitochondrial dynamics of human Sertoli cells under the effect of leptin and ghrelin.
E2
Huete-Ortega 2018 MiPschool Tromso E2High-resolution respirometry: new perspectives for the study of bioenergetics in algae and plants.E2
Garipi 2018 MiPschool Tromso E2Phenotyping mitochondrial metabolism in Barrett’s metaplasia-dysplasia-adenocarcinoma sequence: respiratory capacity, extracelular proton flux and ROS productionE2
Puurand 2018 MiPschool Tromso E2
MiPsociety
Intracellular energy-transfer networks in health and disease – the results of oxygraphic studies.
E2
Cardoso 2018 MiPschool Tromso E2
Luiza Helena Cardoso
Concomitant respiration and ATP production measurements to analyse P»/O2 ratios at physiological normoxia.
E2
Kidere 2018 MiPschool Tromso E2
Dita Kidere
Cytoplasmic hybrid cells as a model to characterize the OXPHOS system: control sample with glutamate metabolism defect.
E2
Storder 2018 MiPschool Tromso E2
Storder J
Investigaton on the role of the mitochondiral deacetylase Sirtuin 3 in adipose tissue.
E2
Fischer 2018 MiPschool Tromso E2
Christine Fischer
Analysis of mitochondrial function in iron deficiency anemia and iron overload conditions.
E2


MiPschool programme Monday, October 22 - Afternoon

 A2. Mitochondrial physiology: protonmotive forceSession
Gnaiger 2018 MiPschool Tromso A2
Erich Gnaiger
The protonmotive force and respiratory control. 1. Coupling of electron transfer reactions to vectorial translocation of protons. 2. From Einstein’s diffusion equation on gradients to Fick’s law on compartments.
Oral
A2


 C3. Selected abstracts: Adipose and liver mitochondriaSession
Torp 2018 MiPschool Tromso C3
MiPsociety
Intracellular complement factor 3 in the heart – a link to metabolism?
Oral
C3
Isola 2018 MiPschool Tromso C3
Raffaela Isola
AMPK deficiency elicits changes in OXPHOS in heart mitochondria.
Oral
C3


MiPschool programme Tuesday, October 23 - Morning

 D2. Cardiac mitochondrial physiology and pathologySession
Vendelin 2018 MiPschool Tromso D2
Marko Vendelin
Modeling actomyosin contraction in the heart muscle.
D2
Oral
Hoppel 2018 MiPschool Tromso D2
Charles Hoppel
Mitochondrial function during ischemia/reperfusion injury.
D2
Oral
  • E3: MitoEAGLE Early Career Investigator Forum - meet the expert


MiPschool programme Tuesday, October 23 – Afternoon

  • E4: Open programme lectures: Programme decisions made during and by the MitoEAGLE/MiPschool
 C4. Selected abstracts: Mitochondrial disorders, remodeling, and degenerative diseasesSession
Vujacic-Mirski 2018 MiPschool Tromso C4
MiPsociety
Development of analytical assays for the detection and quantification of reactive oxygen and nitrogen species in an animal model of type 1 diabetes - ROS formation involving mitochondrial and NADPH oxidase.
C4
Oral
Musiol 2018 MiPschool Tromso C4
MiPsociety
Alpha-tomatine as a novel membrane-permeabilizing agent for mitochondrial respiration measurements.
C4
Oral
Bastos Sant'Anna Silva 2018 MiPschool Tromso C4
Ana Bastos Sant'Anna
Role of succinate in prostate cancer cells: uptake and mitochondrial respiratory function.
C4
Oral
Vella 2018 MiPschool Tromso C4
Joanna Vella
Exome analysis sheds light on mitochondrial disorders.
C4
Oral
Crisostomo 2018 MiPschool Tromso C4
Luis Crisostomo
Mitochondrion at the crosstalk between metabolic disease and dysfunction in male fertility?
C4
Oral
Zdrazilova 2018 MiPschool Tromso C4
MiPsociety
Bioenergetic characterization of skin fibroblasts from patients with congenital disorders of glycosylation.
C4
Oral


MiPschool programme Wednesday, October 24 - Morning

 D3. Mitochondrial function and cardioprotectionSession
Wuest 2018 MiPschool Tromso D3
Wuest Rob
Metabolic flexibility and mitochondrial function in the diabetic heart.
D3
Oral
Boardman 2018 MiPschool Tromso D3
MiPsociety
High fat-load induces cardioprotection in hearts from obese mice.
Oral
D3


Participants and abstracts - alphabetical order

 Presentation
Alves 2018 MiPschool Tromso E2
MiPsociety
Role for mitochondria on the response of highly proliferative and invasive bladder cancer cells to the combined inhibition of mTOR and SIRT1.
Arago 2018 MiPschool Tromso
MiPsociety
No abstract.
Armand 2018 MiPschool Tromso
MiPsociety
No abstract.
Bajzikova 2018 MiPschool Tromso
MiPsociety
No abstract.
Bastos Sant'Anna Silva 2018 MiPschool Tromso C4
Ana Bastos Sant'Anna
Role of succinate in prostate cancer cells: uptake and mitochondrial respiratory function.
Bello 2018 MiPschool Tromso
MiPsociety
No abstract.
Bergmeister 2018 MiPschool Tromso
Lisa Bergmeister
No abstract.
Boardman 2018 MiPschool Tromso D3
MiPsociety
High fat-load induces cardioprotection in hearts from obese mice.
Cardoso 2018 MiPschool Tromso E2
Luiza Helena Cardoso
Concomitant respiration and ATP production measurements to analyse P»/O2 ratios at physiological normoxia.
Crisostomo 2018 MiPschool Tromso C4
Luis Crisostomo
Mitochondrion at the crosstalk between metabolic disease and dysfunction in male fertility?
Dahdah 2018 MiPschool Tromso
MiPsociety
No abstract.
Detraux 2018 MiPschool Tromso
Detraux Damian
No abstract.
Dubouchaud 2018 MiPschool Tromso
Dubouchaud Herve
AMPK deficiency elicits changes in OXPHOS in heart mitochondria.
Ferreira 2018 MiPschool Tromso
Ferreira Luciana
No abstract.
Fischer 2018 MiPschool Tromso E2
Christine Fischer
Analysis of mitochondrial function in iron deficiency anemia and iron overload conditions.
Garipi 2018 MiPschool Tromso E2Phenotyping mitochondrial metabolism in Barrett’s metaplasia-dysplasia-adenocarcinoma sequence: respiratory capacity, extracelular proton flux and ROS production
Gnaiger 2018 MiPschool Tromso A1
Erich Gnaiger
Mitochondrial states and rates: 1. Electron transfer pathways and respiratory control. 2. Coupling control.
Gnaiger 2018 MiPschool Tromso A2
Erich Gnaiger
The protonmotive force and respiratory control. 1. Coupling of electron transfer reactions to vectorial translocation of protons. 2. From Einstein’s diffusion equation on gradients to Fick’s law on compartments.
Goncalo Teixeira 2018 MiPschool Tromso C1
MiPsociety
Subchronic in vivo study for the evaluation of hepatic mitochondrial toxicity induced by silver nanoparticles.
Handl 2018 MiPschool Tromso
MiPsociety
No abstract.
Harper 2018 MiPschool Tromso D1
Mary-Ellen Harper
OXPHOS efficiency in skeletal and cardiac muscles: Proton leaks, ROS and glutathione redox.
Harper 2018 MiPschool Tromso E1
Mary-Ellen Harper
Deacetylation acceleration of BAT thermogenesis.
Heiestad 2018 MiPschool Tromso
Christina Heiestad
No abstract.
Hoppel 2018 MiPschool Tromso D1
Charles Hoppel
Two populations of muscle mitochondria: heart and skeletal muscle.
Hoppel 2018 MiPschool Tromso D2
Charles Hoppel
Mitochondrial function during ischemia/reperfusion injury.
Huete-Ortega 2018 MiPschool Tromso E2High-resolution respirometry: new perspectives for the study of bioenergetics in algae and plants.
Hyrossova 2018 MiPschool Tromso
MiPsociety
No abstract.
Iglesias-Gonzalez 2018 MiPschool Tromso E1 Oscillations in mitochondrial ROS production during the early cell cycles in Xenopus embryos.
Isola 2018 MiPschool Tromso C3
Raffaela Isola
AMPK deficiency elicits changes in OXPHOS in heart mitochondria.
Jansen 2018 MiPschool Tromso C2
MiPsociety
Dietary and pharmacological treatment of diet-induced obese mice – impact on mitochondrial function.
Jaskiewicz 2018 MiPschool Tromso
MiPsociety
No abstract.
Kampa 2018 MiPschool Tromso C2
Rafal Kampa
Cardioprotective flavoniods as a natural modulators of mitoBKCa channel.
Kidere 2018 MiPschool Tromso E2
Dita Kidere
Cytoplasmic hybrid cells as a model to characterize the OXPHOS system: control sample with glutamate metabolism defect.
Krajcova 2018 MiPschool Tromso E2
Adela Krajcova
High-resolution respirometry to assess function of mitochondria in native homogenates of human heart muscle.
Larsen 2018 MiPschool Tromso
Larsen Terje
Local organizer
Li Puma 2018 MiPschool Tromso E2
MiPsociety
Fads2 exacerbates myocardial ischemia-reperfusion injury in mice: role of mitochondria.
Ma 2018 MiPschool Tromso C1
MiPsociety
Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis.
Majtnerova 2018 MiPschool Tromso
MiPsociety
No abstract.
Makrecka-Kuka 2018 MiPschool Tromso E1
Marina Makrecka-Kuka
Cardiac fatty acid oxidation: from in vitro to in vivo.
Marstein 2018 MiPschool Tromso
MiPsociety
No abstract.
MartinsAD 2018 MiPschool Tromso E2
MiPsociety
Mitochondrial dynamics of human Sertoli cells under the effect of leptin and ghrelin.
MartinsJD 2018 MiPschool Tromso C2
MiPsociety
Sweetheart: Cardiac consequences of fetal exposure to maternal gestational diabetes on the offspring mitochondrial function.
Murray 2018 MiPschool Tromso E1
Andrew Murray
OXPHOS protocols: understanding the patterns.
Musiol 2018 MiPschool Tromso C4
MiPsociety
Alpha-tomatine as a novel membrane-permeabilizing agent for mitochondrial respiration measurements.
Pedersen 2018 MiPschool Tromso
MiPsociety
No abstract.
Pereira 2018 MiPschool Tromso C1
Pereira Susana P
Obesity-induced mitochondrial hepatic changes during pregnancy.
Puurand 2018 MiPschool Tromso E2
MiPsociety
Intracellular energy-transfer networks in health and disease – the results of oxygraphic studies.
Schartner 2018 MiPschool Tromso
Schartner Melanie
Schlattner 2018 MiPschool Tromso B1
Uwe Schlattner
Mitochondrial kinases: key players in respiratory control and energy transfer.
Schots 2018 MiPschool Tromso
MiPsociety
Siewiera 2018 MiPschool Tromso E2
Karolina Siewiera
Effect of metformin treatment on blood platelet bioenergetics and platelet function in STZ-diabetic and non-diabetic rats.
Storder 2018 MiPschool Tromso E2
Storder J
Investigaton on the role of the mitochondiral deacetylase Sirtuin 3 in adipose tissue.
Template 2018 MiPschool Tromso
MiPsociety
Torp 2018 MiPschool Tromso C3
MiPsociety
Intracellular complement factor 3 in the heart – a link to metabolism?
Truu 2018 MiPschool Tromso
Truu Laura
No abstract.
Tuncay 2018 MiPschool Tromso C2
MiPsociety
MitoTEMPO ameliorates hyperglycemia induced mitochondrial damage in cardiomyocytes.
Vella 2018 MiPschool Tromso C4
Joanna Vella
Exome analysis sheds light on mitochondrial disorders.
Vendelin 2018 MiPschool Tromso B1
Marko Vendelin
Restrictions to intracellular diffusion of ATP and ADP in cardiomyocytes.
Vendelin 2018 MiPschool Tromso D2
Marko Vendelin
Modeling actomyosin contraction in the heart muscle.
Vendelin 2018 MiPschool Tromso E1
Marko Vendelin
Introducing a platform for primary kinetics data analysis.
Vieira Ligo Teixeira 2018 MiPschool Tromso
MiPsociety
No abstract.
Vujacic-Mirski 2018 MiPschool Tromso C4
MiPsociety
Development of analytical assays for the detection and quantification of reactive oxygen and nitrogen species in an animal model of type 1 diabetes - ROS formation involving mitochondrial and NADPH oxidase.
Wiesner 2018 MiPschool Tromso E1
MiPsociety
Aging-related accumulation of mitochondrial DNA deletions in skeletal muscle occurs preferentially in Type IIb fibers – high mitophagic flux protects Type I fibers.
Wuest 2018 MiPschool Tromso D3
Wuest Rob
Metabolic flexibility and mitochondrial function in the diabetic heart.
Zdrazilova 2018 MiPschool Tromso C4
MiPsociety
Bioenergetic characterization of skin fibroblasts from patients with congenital disorders of glycosylation.
Zobalova 2018 MiPschool Tromso
MiPsociety
No abstract.


Support

MitoEAGLE Scholarships

  1. Eligibility: Participants from all COST countries can apply - MitoEAGLE network.
  2. Late registration: The COST MitoEAGLE grant is a financial support to cover part of the local costs (accommodation, meals).
» Notification of MitoEAGLE scholarships for late registrations until September 20.


Registration and further information

The maximum number of attendees for the MiP/MitoEAGLE Training School 2018 of 65 participants is reached.
closed


MitoEAGLE
  • The MitoEAGLE network aims to improve our knowledge on mitochondrial function in health and disease related to Evolution, Age, Gender, Lifestyle and Environment. Every study of mitochondrial (mt) function and disease is faced with EAGLE as the essential background conditions characterizing the individual patient, subject, study group, species, tissue or even cell line.
Membership in the MitoEAGLE network is open to all researchers sharing an interest in mitochondrial research and medicine
» Join the COST Action CA15203 MITOEAGLE


MiPsociety
  • The MiPsociety is an international organization, based in Europe and operating world-wide and has become a legal body in 2011 continuing a tradition of rigorous mitochondrial bioenergetics; integrating molecular, cellular and organismic physiology and pathology.
Membership is open to all researchers
» MiP membership


How to get there

There are daily flights in each direction between Oslo and Tromsø, flown by SAS and Norwegian (Please note that there are only a few flights on a Saturday)
The same companies also offer some direct flights from Stockholm Arlanda, Copenhagen, and London Gatwick, but these are seasonal (so do check yourselves if these routes are operating and of interest).
Arctic Airlink also offer direct flights to Tromsø from Luleå and Oulu. The nearest train station is Narvik.
It is 3 1/2 hours’ drive from Tromsø, and it is connected to the Swedish, not the Norwegian, rail network (sj.se). There is a bus link from Narvik, but usually, the train does not meet the last bus to Tromsø.


Training school participants arriving in Tromsø before October 20th can find accommodation on the official travel guide to Tromsø (https://www.visittromso.no/en/Troms%C3%B8%20Airport), which gives you an overview of the various hotels in the city, as well as transportation from the airport to the city center, and what to do in Tromsø.
On Saturday morning (from 10:00 h), we will organize a meeting place at the UiT Campus for training school participants arriving throughout the day (information desk and temporary luggage storage).
Here, you will also have access to Internet and, if needed, a quiet spot for work. Take a taxi from the airport to the university and ask the driver to stop at the main (west) entrance of the MH building (link to map). The meeting place will keep open until 21:00 h.
In the city, luggage lockers are available on the 1st floor in the harbour terminal (link to map). These are card-operated lockers, and cost NOK 60 for a 24-hour period. Available during the terminal opening hours: 05.30-02.00 h.
The registration desk opens at 21:00 h at Skarven Bar downtown Tromsø. This will be our assembly point until the Coastal Express arrives around midnight. We will walk from the bar to the harbor terminal, which is just a couple of minutes away (link to map).


Venue and accommodation

Hurtigruten
Bergen to Tromso
Norway
Impressions: Ship and Hurtigruten travel offers



Support

COST EU Logo.PNG

This project has received funding from the European Union's Horizon 2020 research and innovation programme supported by COST (European Cooperation in Science and Technology) under grant agreement No OC-2015-2-19984.



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