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Kuka Janis

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


Kuka Janis


MitoPedia topics: EAGLE 

COST: Member

COST WG2: WG2


Name Kuka Janis, ORCID ID
Institution Latvian Institute of Organic Sythesis, LV
Address Aizkraukles 21, LV1006
City Riga
State/Province
Country Latvia
Email [email protected]
Weblink
O2k-Network Lab


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Publications

 PublishedReference
Gautam 2023 Neurobiol Dis2023Gautam M, Genç B, Helmold B, Ahrens A, Kuka J, Makrecka-Kuka M, Günay A, Koçak N, Aguilar-Wickings IR, Keefe D, Zheng G, Swaminathan S, Redmon M, Zariwala HA, Özdinler PH (2023) SBT-272 improves TDP-43 pathology in ALS upper motor neurons by modulating mitochondrial integrity, motility, and function. https://doi.org/10.1016/j.nbd.2023.106022
Dambrova 2022 Pharmacol Rev2022Dambrova M, Makrecka-Kuka M, Kuka J, Vilskersts R, Nordberg D, Attwood MM, Smesny S, Sen ZD, Guo AC, Oler E, Tian S, Zheng J, Wishart DS, Liepinsh E, Schioth HB. (2022) Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials. https://doi.org/10.1124/pharmrev.121.000408
Liepinsh 2021 Free Radic Biol Med2021Liepinsh E, Kuka J, Vilks K, Svalbe B, Stelfa G, Vilskersts R, Sevostjanovs E, Goldins NR, Groma V, Grinberga S, Plaas M, Makrecka-Kuka M, Dambrova M (2021) Low cardiac content of long-chain acylcarnitines in TMLHE knockout mice prevents ischaemia-reperfusion-induced mitochondrial and cardiac damage. Free Radic Biol Med 177:370-80.
BEC 2020.1 doi10.26124bec2020-0001.v12020Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Makrecka-Kuka 2020 Cardiovasc Drugs Ther2020Makrecka-Kuka Marina, Korzh Stanislava, Videja Melita, Vilks Karlis, Cirule Helena, Kuka Janis, Dambrova Maija, Liepinsh Edgars (2020) Empagliflozin protects cardiac mitochondrial fatty acid metabolism in a mouse model of diet-induced lipid overload. Cardiovasc Drugs Ther 34:791-97.
Makrecka-Kuka 2017 Sci Rep2017Makrecka-Kuka M, Sevostjanovs E, Vilks K, Volska K, Antone U, Kuka J, Makarova E, Pugovics O, Dambrova M, Liepinsh E (2017) Plasma acylcarnitine concentrations reflect the acylcarnitine profile in cardiac tissues. Sci Rep 7:17528.
Liepinsh 2016 Biochem J2016Liepinsh E, Makrecka-Kuka M, Volska K, Kuka J, Makarova E, Antone U, Sevostjanovs E, Vilskersts R, Strods A, Tars K, Dambrova M (2016) Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria. Biochem J 473:1191-202.

Abstracts

 PublishedReference
Kuka 2018 MiP20182018
MiPsociety
The discovery of methyl-GBB - acylcarnitine lowering as an effective strategy to treat cardiometabolic diseases.
Volska 2018 MiP20182018
Kristina Volska
The mechanisms of long-chain acylcarnitine accumulation during ischemia.
Makrecka-Kuka 2017 Abstract MITOEAGLE Barcelona2017
COST Action MITOEAGLE
Fatty acid oxidation evaluation in mitochondria.
Makrecka-Kuka 2016 Abstract MitoFit Science Camp 20162016Long-chain acylCoAs vs acylcarnitines in mitochondrial bioenergetics: from in vitro to in vivo.
Makrecka 2013 Abstract MiP20132013Makrecka-Kuka M, Volska K, Kuka J, Liepins E, Dambrova M (2013) The accumulation of long chain acyl-carnitines is a major cause of mitochondrial damage during ischemia. Mitochondr Physiol Network 18.08.

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