Cardoso 2024 MitoFit

From Bioblast
Publications in the MiPMap
Cardoso LHD, Gnaiger E (2024) OXPHOS coupling and uncoupling. MitoFit Preprints 2024.2. https://doi.org/10.26124/mitofit:2024-0002

Β» MitoFit Preprints 2024.2.

MitoFit pdf

OXPHOS coupling and uncoupling.

Cardoso Luiza HD, Gnaiger Erich (2024) MitoFit Prep

Abstract: Coupling of OXPHOS is classically studied by comparing ADP-stimulated O2 flux (OXPHOS capacity P at saturating ADP and Pi concentrations) with non-phosphorylating LEAK respiration L, maintained mainly to compensate for the proton leak at high chemiosmotic potential in mitochondrial preparations supplied with fuel substrates to support mitochondrial electron transfer. However, measurement of the non-coupled electron transfer capacity E (ET capacity at collapsed chemiosmotic potential) yields additional information on coupling, since ET capacity may exceed OXPHOS capacity.
β€’ Keywords: electron transfer capacity, LEAK respiration, mitochondria, oxidative phosphorylation β€’ Bioblast editor: Tindle-Solomon L β€’ O2k-Network Lab: AT Innsbruck Oroboros

ORCID: ORCID.png Cardoso Luiza HD, ORCID.png Gnaiger Erich

Spotlight

Cited by

Gnaiger 2024 Ambiguity crisis.jpg
Gnaiger E (2024) Addressing the ambiguity crisis in bioenergetics and thermodynamics. MitoFit Preprints 2024.3. https://doi.org/10.26124/mitofit:2024-0003


Labels: MiParea: Respiration 




Regulation: Coupling efficiency;uncoupling  Coupling state: LEAK, OXPHOS, ET 


Gnaiger 2024 MitoFit 

Cookies help us deliver our services. By using our services, you agree to our use of cookies.