https://wiki.oroboros.at/api.php?action=feedcontributions&user=Tindle+Lisa&feedformat=atom
Bioblast - User contributions [en]
2024-03-29T00:31:35Z
User contributions
MediaWiki 1.36.1
https://wiki.oroboros.at/index.php?title=MiPNet18.10_O2k-Specifications&diff=246651
MiPNet18.10 O2k-Specifications
2024-03-26T15:56:58Z
<p>Tindle Lisa: </p>
<hr />
<div>{{OROBOROS header page name}}<br />
{{Publication<br />
|title=[[Image:Logo OROBOROS INSTRUMENTS.jpg|right|60px|link=http://www.oroboros.at|Oroboros ]] O2k-specifications for respirometry and comprehensive OXPHOS analysis.<br />
|info=[[File:PDF.jpg|100px|link=http://wiki.oroboros.at/images/d/db/MiPNet18.10_O2k_specifications.pdf|Bioblast pdf]] » [http://www.bioblast.at/index.php/File:MiPNet18.10_O2k_specifications.pdf Versions]<br />
|authors=Oroboros<br />
|year=2024-03-26<br />
|journal=Mitochondr Physiol Network<br />
|abstract=Gnaiger E (2024) O2k-Specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(10):1-8. <br />
{{MiPNet pdf page linking to MitoPedia}}<br />
|mipnetlab=AT Innsbruck Oroboros<br />
}}<br />
== Further information ==<br />
::::» [[MiPNet06.05 Test Experiments on O2k-Specifications]]<br />
::::» [[Comparison of respirometric methods]]<br />
<br /><br />
'''Acknowledgements'''<br />
[[File:Template NextGen-O2k.jpg|left|400px|link=NextGen-O2k]]<br />
<br/><br />
<br/><br />
<br/><br />
<br/><br />
<br/><br />
<br />
{{Labeling<br />
|area=Respiration, Instruments;methods<br />
|organism=Human<br />
|tissues=Fibroblast<br />
|preparations=Permeabilized cells, Permeabilized tissue, Homogenate, Isolated mitochondria, SMP, Intact cells<br />
|instruments=Oxygraph-2k, TIP2k, O2k-Fluorometer, pH, NO, TPP, Ca, Theory<br />
|additional=Comparison of respirometric methods, MitoFit2022QC<br />
}}</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=File:MiPNet18.10_O2k_specifications.pdf&diff=246650
File:MiPNet18.10 O2k specifications.pdf
2024-03-26T15:55:52Z
<p>Tindle Lisa: Tindle Lisa uploaded a new version of File:MiPNet18.10 O2k specifications.pdf</p>
<hr />
<div>* '''Current Version 10: 2024-03-26.''' Gnaiger E (2024) O2k-Specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(10):1-8.<br />
::* Version 09: 2019-09-19.''' Gnaiger E (2019) O2k_FluoRespirometer: specifications or respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(09):1-8.<br />
::* Version 08: 2018-05-02.''' Gnaiger E (2018) O2k_FluoRespirometer: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(08):1-8.<br />
::* Version 07: 2017-08-08.''' Gnaiger E (2017) O2k_FluoRespirometer: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(07):1-8.<br />
::* Version 06: 2015-10-05. Gnaiger E, Fasching M (2015) Oxygraph-2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(06):1-8.<br />
::* Version 05: 2015-06-10. Gnaiger E, Fasching M (2015) Oxygraph-2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(05):1-8.<br />
::* Version 04: 2014-06-12. Gnaiger E, Fasching M (2014) Oxygraph-2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(04):1-8.<br />
::* Version 03: 2014-02-10. Gnaiger E, Fasching M (2014) Oxygraph-2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(03):1-8.<br />
::* Version 02: 2013-08-25. Gnaiger E, Fasching M (2013) O2k versus multiwell respirometer. Mitochondr Physiol Network 18.10(02).<br />
::* Version 01: 2013-08-24. Gnaiger E, Fasching M (2013) O2k versus multiwell respirometer. Mitochondr Physiol Network 18.10(01).</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=File:MiPNet18.10_O2k_specifications.pdf&diff=246649
File:MiPNet18.10 O2k specifications.pdf
2024-03-26T15:55:12Z
<p>Tindle Lisa: </p>
<hr />
<div>* '''Current Version 10: 2024-03-26.''' Gnaiger E (2024) O2k-Specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(10):1-8.<br />
::* Version 09: 2019-09-19.''' Gnaiger E (2019) O2k_FluoRespirometer: specifications or respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(09):1-8.<br />
::* Version 08: 2018-05-02.''' Gnaiger E (2018) O2k_FluoRespirometer: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(08):1-8.<br />
::* Version 07: 2017-08-08.''' Gnaiger E (2017) O2k_FluoRespirometer: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(07):1-8.<br />
::* Version 06: 2015-10-05. Gnaiger E, Fasching M (2015) Oxygraph-2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(06):1-8.<br />
::* Version 05: 2015-06-10. Gnaiger E, Fasching M (2015) Oxygraph-2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(05):1-8.<br />
::* Version 04: 2014-06-12. Gnaiger E, Fasching M (2014) Oxygraph-2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(04):1-8.<br />
::* Version 03: 2014-02-10. Gnaiger E, Fasching M (2014) Oxygraph-2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(03):1-8.<br />
::* Version 02: 2013-08-25. Gnaiger E, Fasching M (2013) O2k versus multiwell respirometer. Mitochondr Physiol Network 18.10(02).<br />
::* Version 01: 2013-08-24. Gnaiger E, Fasching M (2013) O2k versus multiwell respirometer. Mitochondr Physiol Network 18.10(01).</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=File:MiPNet18.10_O2k_specifications.pdf&diff=246648
File:MiPNet18.10 O2k specifications.pdf
2024-03-26T15:53:38Z
<p>Tindle Lisa: Tindle Lisa uploaded a new version of File:MiPNet18.10 O2k specifications.pdf</p>
<hr />
<div>* '''Current Version 09: 2019-09-19.''' Gnaiger E (2019) O2k_FluoRespirometer: specifications or respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(09):1-8.<br />
::* Version 08: 2018-05-02.''' Gnaiger E (2018) O2k_FluoRespirometer: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(08):1-8.<br />
::* Version 07: 2017-08-08.''' Gnaiger E (2017) O2k_FluoRespirometer: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(07):1-8.<br />
::* Version 06: 2015-10-05. Gnaiger E, Fasching M (2015) Oxygraph-2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(06):1-8.<br />
::* Version 05: 2015-06-10. Gnaiger E, Fasching M (2015) Oxygraph-2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(05):1-8.<br />
::* Version 04: 2014-06-12. Gnaiger E, Fasching M (2014) Oxygraph-2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(04):1-8.<br />
::* Version 03: 2014-02-10. Gnaiger E, Fasching M (2014) Oxygraph-2k and O2k-MultiSensor system: specifications for respirometry and comprehensive OXPHOS analysis. Mitochondr Physiol Network 18.10(03):1-8.<br />
::* Version 02: 2013-08-25. Gnaiger E, Fasching M (2013) O2k versus multiwell respirometer. Mitochondr Physiol Network 18.10(02).<br />
::* Version 01: 2013-08-24. Gnaiger E, Fasching M (2013) O2k versus multiwell respirometer. Mitochondr Physiol Network 18.10(01).</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Current_week_ecosystem_agenda&diff=246646
Template:Current week ecosystem agenda
2024-03-26T08:44:01Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:Science for Ukraine}}<br />
<br />
2024 Week 13<br />
<br />
* '''Mar-25 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Living cells or intact cells? '''<br><br />
Living cells are frequently labelled as ''intact cells'' in the sense of the total cell count, but ''intact'' may suggest dual meanings of viable or unaffected by a disease or mitochondrial injury. <br><br />
- »'''[[Living cells]]'''«, »'''[[BEC 2020.1|Gnaiger 2020 BEC Mitochondrial physiology]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''« <br><br />
- communicated by »[[Leo Elettra]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Mar-26 Tu''' <br />
----<br />
* '''Mar-27 We''' <br />
----<br />
* '''Mar-28 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''"Introduction to the new models available with the NextGen was immensely helpful. This [[MiPNet28.02_IOC162_Schroecken_AT|workshop]] has been critical for implementation of new techniques and advancement of my research."'''''<br><br />
[[Zunica Elizabeth]], from the O2k-Network »[[US LA Baton Rouge Noland RC]]«<br><br />
- »'''[[O2k-Feedback]]'''«<br><br />
|}<br />
----<br />
* '''Mar-29 Fr'''<br />
----<br />
'''<big>Next Week</big>'''<br />
2024 Week 14<br />
<br />
* '''Apr-01 Mo'''<br />
April - Parkinson's Awareness Month <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Although the chain of events leading to this respiration deficit is currently not understood, the findings constitute a robust assay for the progressive pathology induced by PINK1 deficiency.''' <br><br />
* Gispert S, Ricciardi F, Kurz A, Azizov M, Hoepken HH, Becker D, Voos W, Leuner K, Müller WE, Kudin AP, Kunz WS, Zimmermann A, Roeper J, Wenzel D, Jendrach M, García-Arencíbia M, Fernández-Ruiz J, Huber L, Rohrer H, Barrera M, Reichert AS, Rüb U, Chen A, Nussbaum RL, Auburger G (2009) Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration. [[Gispert 2009 PLoS One|»Bioblast link«]]<br />
:from the O2k-Network »[[US CA San Francisco Nussbaum RL]]« and »[[DE Frankfurt Eckert GP]]«<br />
|} <br />
----<br />
* '''Apr-02 Tu''' <br />
----<br />
* '''Apr-03 We''' <br />
----<br />
* '''Apr-04 Th''' <br />
----<br />
* '''Apr-05 Fr'''<br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template_talk:Next_oroboros_ecosystem_agenda&diff=246643
Template talk:Next oroboros ecosystem agenda
2024-03-25T15:15:00Z
<p>Tindle Lisa: /* MiPNet */</p>
<hr />
<div>__TOC__<br />
<br />
::::[[User:Antunes Diana|Antunes Diana]] ([[User talk:Antunes Diana|talk]]) 08:58, 5 May 2020 (CEST) Format for new Agenda/Alerts entries:<br />
<pre style="display: inline-block;"><br />
{|<br />
| logos<br />
| title in bold <br><br />
- link<br />
|}<br />
</pre><br />
<br />
''e.g.,''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Red-loss of data.png|25px|Warning: loss of data]]<br />
|'''Did you know that the proper use of TIP2k-Filter Papers may avoid an unstable O2 slope neg. signal during Instrumental background correction?''' <br><br />
- »[[Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._signal_in_O2_instrumental_BG|Instrumental background]]« and »[[TIP2k Filter Papers]]«<br />
|}<br />
:::: ''See the scheme'':<br />
<br><br />
[[Image:TEMPLATE ALERT.png|none|900px|Agenda/Alerts body text format]]<br />
<br />
<br />
== MitoPedia alert ==<br />
::: Example:<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Measuring fatty acid oxidation (FAO)-linked respiration requires a low concentration of malate '''<br><br />
In the absence of malate, accumulation of Acetyl-CoA inhibits FAO. <br><br />
- »'''[[Fatty acid oxidation pathway control state]]'''«, »'''[https://www.bioblast.at/index.php/Gnaiger_2020_BEC_MitoPathways Mitochondrial Pathways: Chapter 5]'''« <br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Cardoso Luiza]]« <br />
|}<br />
<br />
<br />
=== Next ===<br />
<br />
March 11th<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
<br />
March 25th<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Living cells or intact cells? '''<br><br />
Living cells are frequently labelled as ''intact cells'' in the sense of the total cell count, but ''intact'' may suggest dual meanings of viable or unaffected by a disease or mitochondrial injury. <br><br />
- »'''[[Living cells]]'''«, »'''[[BEC 2020.1]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''« <br><br />
- communicated by »[[Leo Elettra]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
<br />
April 8th<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Is fatty acid oxidation (FAO) considered as CI- or CII-driven respiration? '''<br><br />
Neither. FAO generates acetyl-coA, which will enter the TCA cycle, and FADH<sub>2</sub>, resulting in simultaneous electron transfer into the Q-junction through the electron transferring flavoprotein complex (CETF) and Complex I. <br><br />
- »'''[[Fatty acid oxidation]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''«, »'''[[Gnaiger 2023 MitoFit CII]]'''« <br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Willis Jaime R]]« <br />
|}<br />
<br />
=== Under construction ===<br />
<br />
on hold until the page is updated<br />
:{|<br />
| width="100" align="center" |[[File:FAT4BRAIN logo.png|right|80px|link=https://wiki.oroboros.at/index.php/FAT4BRAIN|FAT4BRAIN]]<br />
|'''A FAO-mito-CNS platform to help fatty acid-related respiration measurements was developed in the FAT4BRAIN project''' <br><br />
- » [[FAT4BRAIN_FAO-mito-CNS_platform|FAT4BRAIN FAO-mito-CNS platform]] «<br />
|}<br />
<br />
== O2k-Brief alert ==<br />
:::* Example:<br />
:{|<br />
| width="100" align="center" | [[File:O2k-brief.png|45px|link=http://wiki.oroboros.at/index.php/O2k-brief|O2k-brief repository]]<br />
|'''Antitumoral properties of triterpenic acid functionalized gold nanoparticles arise from decreasing mitochondrial respiration''' <br><br />
* Mioc M, Mioc A, Racoviceanu R, Ghiulai R, Prodea A, Milan A, Barbu Tudoran L, Oprean C, Ivan V, Șoica C (2023) The antimelanoma biological assessment of triterpenic acid functionalized gold nanoparticles. [[Mioc 2023 Molecules|»Bioblast link«]]<br />
|}<br />
=== Next ===<br />
<br />
== O2k-Publications alert ==<br />
<br />
:::* Example: <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Mitochondria–nucleus communication and its integration within the maintenance of cellular homeostasis constitute key determinants of cellular fate and organism health in the context of cellular stress, homeostasis perturbation, and disease"''' <br><br />
* Temelie M, Talpur R, Dominguez-Prieto M, Dantas Silva A, Cenusa C, Craciun L, Savu DI, Moisoi N (2023) Impaired integrated stress response and mitochondrial integrity modulate genotoxic stress impact and lower the threshold for immune signalling. [[Temelie 2023 Int J Mol Sci|»Bioblast link«]]<br />
:from the O2k-Network »[[UK Leicester Moisoi N]]«<br />
|}<br />
<br />
===='''Author names of O2k-Publications/ Brief for the Agenda vs Bioblast''' ==== <br />
<br />
__NOTOC__ [[File:Expand.png|right|25px|Click to expand or collaps]]<br />
<div class="toccolours mw-collapsible mw-collapsed"><br />
'''Guidelines to update a reference'''<br />
<div class="mw-collapsible-content"><br />
::When creating an O2k-Publication/Brief alert, it is the responsibility of the author to check if the reference is accordingly to the correct guidelines:<br />
[[File:Reference example.png|900px]]<br />
::Correct format for a person called “First Name Surname”: <br />
::In the gray box should be “Surname FN” - '''From where references to be used as O2k-Publication/Brief alerts are copied from.'''<br />
[[File:Gray box reference.png|900px]]<br />
::In the links should be “ Surname First N”<br />
[[File:Authors names links reference.png|900px]]<br />
::'''How to edit:'''<br />
:::A) Check if all authors with profiles in Bioblast (blue links) have their profiles with full name. If they have, proceed to next step (B). If not, you need to move it following the steps “How to move a profile” below.<br />
:::B) Click in “Edit with form”.<br />
:::C) The gray box is edited in “Reference” and the links are changed in “Author(s)”. Change it accordingly and click in “save page” at the end of the page.<br />
[[File:Editing reference.png|900px]]<br />
<br />
'''How to move a profile (instructions sent by Marija):'''<br />
<br />
So let’s take for example my page: <br />
[[Beno M]] <br />
[https://wiki.oroboros.at/index.php?title=Beno_Marija&redirect=no]<br />
<br />
::As you can see there is a redirect from Beno Marija to Beno M. What has to be done is to switch the content of those pages. Here are the steps: <br />
:::1. Go to e.g. “Beno M” on edit<br />
:::2. Click on “Move”<br />
:::3. Change the new title to the full name of the person. In my case it will be Beno M to Beno Marija <br />
[[File:BenoMreference.jpg|500px]]<br />
:::4. Now it should look like that: <br />
[[File:BenoMarijaReference.png|500px]]<br />
:::5. Click on “Move” and leave all the ticked boxes<br />
:::6.Done<br />
::After that you can continue in step B.<br />
::If you have any doubt you can contact Cristiane, Marija or Mario.<br />
</div><br />
</div><br />
<br />
=== Next ===<br />
<br />
:{|<br />
| width="100" align="center" |[[File:BEC2023.3.jpg|right|150px|link=https://doi.org/10.26124/bec:2023-0004| Oliveira 2023 BEC]]<br />
|'''A BEC Spotlight on Rodríguez et al's ''Drosophila'' mitochondrial research methodology''' <br><br />
* Oliveira MF, Aveiro Y, Couto-Lima CA (2023) A navigation chart to avoid turbulence in Drosophila mitochondrial research. Bioenerg Commun 2023.4. https://doi.org/10.26124/bec:2023-0004<br />
:from the O2k-Network »[[BR Rio de Janeiro Oliveira MF]]«<br />
|}<br />
<br />
March 14th<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|}<br />
<br />
== MiPNet ==<br />
:::* Example: <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' "No bubbles should be trapped in the electrolyte reservoir after membrane application and mounting"'''<br><br />
<br />
- »'''[[MiPNet28.10 SmartPOS-service]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[]]«<br />
|}<br />
<br />
=== Next ===<br />
April 4th<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' "Why is it important to check for the sensitivity towards H<sub>2</sub>O<sub>2</sub> in the Amplex UltraRed (AmR) assay<br />
The sensitivity is influenced by experimental time, medium composition, added chemicals and sample, requiring multiple H<sub>2</sub>O<sub>2</sub> calibrations throughout the measurement. Prior to the assay, ensure also that sensitivity is within the recommended range after AmR calibration.'''<br><br />
<br />
- »'''[[MiPNet20.14 AmplexRed H2O2-production]]'''«, »'''[[MiPNet24.10 H2O2 flux analysis]]'''«, »'''[https://wiki.oroboros.at/index.php/Amplex_UltraRed#Calibration_with_H2O2 Amplex UltraRed]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Schmitt Sabine]]«<br />
|}<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' "Why is it important to check for the sensitivity towards H<sub>2</sub>O<sub>2</sub> in the Amplex UltraRed (AmR) assay<br />
The sensitivity is influenced by experimental time, medium composition, added chemicals and sample, requiring multiple H<sub>2</sub>O<sub>2</sub> calibrations throughout the measurement. After the initial AmR calibration, ensure that the sensitivity is within the recommended range.'''<br><br />
<br />
- »'''[[MiPNet24.10 H2O2 flux analysis]]'''«, »'''[https://wiki.oroboros.at/index.php/Amplex_UltraRed#Calibration_with_H2O2 Amplex UltraRed]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Schmitt Sabine]]«<br />
|}<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' "Why is it important to check for the sensitivity towards H<sub>2</sub>O<sub>2</sub> in the Amplex UltraRed (AmR) assay<br />
The sensitivity is influenced by experimental time, medium composition, added chemicals and sample, requiring multiple H<sub>2</sub>O<sub>2</sub> titrations throughout the measurement for subsequent calibration. After the initial AmR calibration, ensure that the sensitivity is within the recommended range.'''<br><br />
<br />
- »'''[[MiPNet24.10 H2O2 flux analysis]]'''«, »'''[https://wiki.oroboros.at/index.php/Amplex_UltraRed#Calibration_with_H2O2 Amplex UltraRed]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Schmitt Sabine]]«<br />
|}<br />
<br />
== O2k-Open Support alert ==<br />
:::*Examples:<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Yellow-take care.png|25px|Info: take care]]<br />
|'''Does your polarographic oxygen sensor (POS) need a deep clean?'''<br><br />
A POS with a very dark anode might need several rounds of ammonia cleaning, possibly including prolonged exposure overnight to restore performance specifications. <br />
<br><br />
- »'''[[MiPNet19.18B POS-service|POS service]]'''«<br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Leo Elettra]]«<br />
|}<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Red-loss of data.png|25px|Warning: loss of data]] <br />
|'''Did you know that a humid environment and/or liquid spillage may lead to a high raw POS signal [V]?'''<br><br />
See how to clean and dry the electrical connections of the OroboPOS-Connector.<br><br />
- »'''[[OroboPOS-Connector#Cleaning_the_electrical_connections|Cleaning the electrical connections]]'''«<br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Unusual stirrer bar rotation? '''<br><br />
A “jumping” stirrer or a slow rotation of the stirrer bar may indicate a problem either with the stirrer itself or with the cleaning of the glass chamber. <br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/Stirrer-Bar%5Cwhite_PVDF%5C15x6_mm#Technical_support Stirrer bar - technical support]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
<br />
=== Next ===<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' How to store the POS overnight and up to several months? '''<br><br />
Fill the chamber and the receptacle of the loosely inserted stopper with 70 % EtOH, add the Cover-slip and switch off the O2K.<br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/MiPNet19.03_O2k-cleaning_and_ISS O2k-cleaning and ISS]'''«<br><br />
- communicated by »[[Leo Elettra]]« and »[[Grings Mateus]]«<br />
|}<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test? '''<br><br />
Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.<br />
<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
<br />
March 18<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' What if ''Alert: Error in titrations!'' appears in your O2 analysis template file? '''<br><br />
The O2 analysis template recognizes discrepancies between the protocol selected in the first tab and the imported marks. Check the titration sequence and mark names against the protocol copied from the DLD file.<br><br />
- »'''[[MiPNet24.06 Oxygen flux analysis - DatLab 7.4|O<sub>2</sub> flux analysis]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
<br />
== O2k-Feedback alert ==<br />
:::* Example (if the person has a profile, link the name to the profile with [[Cecatto C| Cristiane Cecatto]]:<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“Thank you very much for your thorough help. I appreciate the time you took to provide me with all the answers and supportive literature to realize the potential of the O2k-respirometer in bioenergetics research”'''''<br><br />
Badr Ibrahim, PhD from Betterhumans Inc., US<br />
<br><br />
- »'''[[O2k-Feedback]]'''«<br><br />
|}<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“Thank you very much for your thorough help. I appreciate the time you took to provide me with all the answers and supportive literature to realize the potential of the O2k-respirometer in bioenergetics research”'''''<br><br />
Badr Ibrahim, PhD from the O2k-Network »[[UK Leicester Moisoi N]]«<br><br />
- »'''[[O2k-Feedback]]'''«<br><br />
|}<br />
<br />
=== Next ===<br />
<br />
== MitoFit Preprints ==<br />
:::* Example:<br />
:{|<br />
| width="100" align="center"|[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''From preprint to BEC manuscript with published Open Peer Reviews:'''<br><br />
*Komlódi T, Sobotka O, Gnaiger E (2021) Facts and artefacts on the oxygen dependence of hydrogen peroxide production using Amplex UltraRed. Bioenerg Commun 2021.4. [[doi:10.26124/BEC:2021-0004]]<br />
:from the O2k-Network »[[AT Innsbruck Oroboros]]« <br />
|}<br />
<br />
=== Next ===<br />
<br />
== Under discussion ==<br />
<br />
This one needs an update of the Bioblast page and clarification of MiPNet06.03<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Did you enter the correct oxygen solubility factor in DatLab?'''<br><br />
The oxygen solubility factor of the incubation medium, F<sub>M</sub>, expresses the effect of the salt concentration on oxygen solubility relative to pure water. The correct oxygen solubility factor of your experimental medium or buffer needs to be entered in DatLab for proper calculation of the oxygen concentration.<br />
<br><br />
- »'''[[Oxygen solubility factor|Oxygen solubility factor]]'''«<br><br />
- communicated by »[[Schmitt Sabine]]« and »[[ ]]«<br />
<br />
|}<br />
<br />
This one needs a BioBlast link:<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' When filling in the volume of uncoupler in the DatLab mark or the excel template, should one enter the total volume added or the volume to get to the highest flux?'''<br><br />
The volume added until the mark, equal to the highest flux, should be entered. Anything titrated after this mark should be summed to the other volumes before the next mark because this will be considered to calculate the sample dilution. <br />
<br><br />
- »'''[[LINK|LINK]]''' and '''[[MiPNet24.06_Oxygen_flux_analysis_-_DatLab_7.4|O<sub>2</sub> flux analysis with DatLab 7.4]]'''«<br><br />
- communicated by »[[Cardoso Luiza]]« and »[[ ]]«<br />
|}<br />
<br />
<br />
== Removed for correction ==<br />
* '''Nov-30 Mo''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Noisy oxygen signal? Check the OroboPOS and OroboPOS-Connector to clean electrical connections.'''<br><br />
Contaminating grease, salt crystals and moisture can be removed with a dry paper cloth or a paper cloth moistened with water and then absolute ethanol. <br><br />
- »[[OroboPOS-Connector#Cleaning_the_electrical_connections |Cleaning the electrical connections]]« <br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Komlodi Timea]]«<br />
|}<br />
WGT recommended not to use water for cleaning. Erich introduced water for cleaning to remove salt crystals.<br />
<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Red-loss of data.png|25px|Warning: loss of data]]<br />
|'''Do you perform the ''leaky chamber test'' after chamber assembly? '''<br><br />
An unnoticed leak from the chamber may affect your data, therefore we recommend performing the ''Leaky chamber test'' - especially after chamber reassembly. <br><br />
- »[[Talk:O2k-Chamber_MitoPedia#Leaky_Chamber|Leaky chamber test]]« and » https://intern.oroboros.at/index.php/Overnight_test_after_O2k-chamber_assembly«<br />
|}</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Club17_2024_Innsbruck_AT&diff=246637
Club17 2024 Innsbruck AT
2024-03-25T08:01:49Z
<p>Tindle Lisa: </p>
<hr />
<div>{{MitoGlobal header page name}}<br />
<br />
{{Publication<br />
|title=[[File:Tirol sat lining RGB.png|right|200px|link=https://www.standort-tirol.at/|Standortagentur Tirol]]'''Innsbruck AT''', 2024 Mar 21. Club17 <br />
|info= [https://www.standort-tirol.at/26-club17--21maerz2024 Event website]<br />
|authors= Standortagentur Tirol<br />
|year=2024-03-21<br />
|journal=MitoGlobal<br />
|abstract= Club17, Innsbruck, Austria, 2024<br />
}}<br />
<br />
== Venue ==<br />
:::: Standortagentur Tirol<br />
:::: Ing.-Etzel-Straße 17/ 2.OG<br />
:::: 6020 Innsbruck <br />
:::: Austria <br />
<br />
== Organizers ==<br />
:::: Standortagentur Tirol<br />
:::: Vera Schrattmaier<br />
<br />
== Program ==<br />
:::: Please see the [https://www.standort-tirol.at/26-club17--21maerz2024 event website].<br />
<br />
<br />
== Oroboros at Club17 ==<br />
:::: [[Laner Verena| Verena Laner]]: Functional Mitochondrial Diagnostics, ''Mar 21, 17:00'', presentation held in German<br />
:::: The project [[Functional Mitochondrial Diagnostics]] is a collaboration between VASCage and Oroboros Instruments with the aim of establishing in-vitro mitochondrial diagnostic standards. You can learn more exciting information about this topic during the presentation.<br />
<br />
<br />
:::: German: Funktionale Mitochondriendiagnostik<br />
:::: Das Projekt [[Functional Mitochondrial Diagnostics| Funktionale Mitochondriendiagnostik]] ist eine Zusammenarbeit zwischen VASCage und Oroboros Instruments mit dem Ziel, in vitro mitochondriale diagnostische Standards zu etablieren. Weitere spannende Informationen zu diesem Thema erhalten Sie während dem Vortrag.<br />
<br />
<br />
{{Labeling<br />
|instruments=<br />
|additional=2024, MitoGlobal, ORO, Mitochondrial Diagnostics events<br />
}}<br />
<br />
<br />
[[Image:MitoGlobal.jpg|right|80px|link=http://www.bioblast.at/index.php/MitoGlobal|MitoGlobal]] <br />
Listed under [[MitoGlobal Events]].</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=EU-METAHEART_MC2_Meeting_2024_Antalya_TR&diff=246636
EU-METAHEART MC2 Meeting 2024 Antalya TR
2024-03-25T08:01:21Z
<p>Tindle Lisa: </p>
<hr />
<div>{{MitoGlobal header page name}}<br />
<br />
{{Publication<br />
|title=[[File:COST Logo.jpg|left|120px|COST Action]][[File:EU-METAHEART logo.jpg|right|70px|EU-METAHEART]]'''Antalya TR''', 2024 Mar 18-21. EU-METAHEART MC2 Meeting<br />
|info= [[EU-METAHEART]]<br />
|authors= [[EU-METAHEART]]<br />
|year=2024-03-18<br />
|journal=MitoGlobal<br />
|abstract= COST CA22169 METAHEART Management Committee meeting MC2, Antalya, Turkey, 2024<br />
}}<br />
<br />
== Venue ==<br />
:::: Miracle Resort Hotel https://www.miraclehotel.com/<br />
<br />
== Organizers ==<br />
:::: COST Association - European Cooperation in Science and Technology<br />
:::: Action Contact: [[Maack C|Prof Christoph Maack]], University Clinic Würzburg, DE<br />
:::: [[Gnaiger Erich |Erich Gnaiger]] is part of the Management Committee of CA22169 - EUropean network to tackle METAbolic alterations in HEART failure (EU-METAHEART)<br />
<br />
== Program ==<br />
:::: Program available [[Media:EU-METAHEART_MC2_Meeting_Antalya_03-2024_programme.pdf|here]]<br />
<br />
== Oroboros at EU-METAHEART MC2 Meeting ==<br />
:::: [[Gnaiger Erich]]: [[Donnelly_2024_EU-METAHEART_MC2_Meeting |Impact of hypoxia on mitochondrial function: effects on oxidative phosphorylation, mitochondrial membrane potential, redox state of coenzyme Q, and calcium uptake]], ''Mar 19, 15:05-15:20''<br />
<br />
== Support ==<br />
:::: [[File:Flag yellow low.jpg|left|100px]] Funded by the European Union.<br />
<br/><br />
<br/><br />
:::: [[Image:COST Logo.jpg|left|140pxE]] COST (European Cooperation in Science and Technology) is a funding organisation for research and innovation networks. Our Actions help connect research initiatives across Europe and beyond and enable researchers and innovators to grow their ideas in any science and technology field by sharing them with their peers. COST Actions are bottom-up networks with a duration of four years that boost research, innovation and careers. - [http://www.cost.eu/ www.cost.eu]<br />
<br />
<br />
{{Labeling<br />
|additional=2024, MitoGlobal, ORO, EU-METAHEART events<br />
}}<br />
<br />
<br />
[[Image:MitoGlobal.jpg|right|80px|link=http://www.bioblast.at/index.php/MitoGlobal|MitoGlobal]] <br />
Listed under [[MitoGlobal Events]].</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:MitoPediaAlert2024&diff=246635
Template:MitoPediaAlert2024
2024-03-25T07:48:28Z
<p>Tindle Lisa: </p>
<hr />
<div>:::::: <big>''A collection from the »[[OROBOROS_INSTRUMENTS|Bioblast Agenda]]«</big><br />
__TOC__<br />
== Mar 2024 ==<br />
* '''Mar-25 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Living cells or intact cells? '''<br><br />
Living cells are frequently labelled as ''intact cells'' in the sense of the total cell count, but ''intact'' may suggest dual meanings of viable or unaffected by a disease or mitochondrial injury. <br><br />
- »'''[[Living cells]]'''«, »'''[[BEC 2020.1]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''« <br><br />
- communicated by »[[Leo Elettra]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
<br />
* '''Mar-11 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
----<br />
== Feb 2024 ==<br />
* '''Feb-26 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' ATP synthase = phosphorylation system? '''<br><br />
No, the phosphorylation system consists of adenine nucleotide translocase, phosphate carrier, and ATP synthase, which carry out the steps in the phosphorylation pathway. <br><br />
- »'''[[Phosphorylation pathway]]'''«, »'''[https://www.bioblast.at/index.php/Gnaiger_2020_BEC_MitoPathways Mitochondrial Pathways: Chapter 2.2]'''« <br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Feb-12 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' What is the O<sub>2</sub> solubility factor of the medium (''F''<sub>M</sub>) and why is it important? '''<br><br />
''F''<sub>M</sub> expresses the effect of the salt concentration on oxygen solubility relative to pure water, and varies depending on the temperature and composition of the medium. The correct ''F''<sub>M</sub> needs to be entered in DatLab when performing an air calibration. <br><br />
- »'''[[Oxygen solubility factor]]'''« , »'''[[Oxygen_calibration_-_DatLab#Air_calibration_in_DatLab|Air calibration in DatLab]]'''« <br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
== Jan 2024 ==<br />
* '''Jan-31 We''' <br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Can the S-pathway O<sub><small>2</small></sub> flux be derived by subtracting N-pathway O<sub><small>2</small></sub> flux from NS-pathway O<sub><small>2</small></sub> flux?'''<br><br />
No, the sum of the O<sub><small>2</small></sub> fluxes measured in the presence of NADH-linked substrates alone and succinate as the single substrate is typically higher than using a combination of all these substrates. This effect is described as incomplete additivity: <br><br />
- »'''[[Additive effect of convergent electron flow]]'''« <br><br />
- communicated by »[[Cardoso Luiza]]« and »[[Grings Mateus]]« <br />
|}<br />
----<br />
* '''Jan-02 Tu'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' New year, new state? What is REN state? '''<br><br />
REN state is now distinguished from ROX state: REN is measured in mitochondrial preparations without addition of substrates, whereas ROX is due to oxidative side reactions remaining after inhibition of the electron transfer pathway. <br> <br />
- »'''[[Residual endogenous substrates|REN]]'''«, »'''[[Residual oxygen consumption|ROX]]'''« <br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]« <br />
|} <br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:O2k-OpenSupportAlert2024&diff=246634
Template:O2k-OpenSupportAlert2024
2024-03-25T07:46:48Z
<p>Tindle Lisa: </p>
<hr />
<div>:::::: <big>''Currently Answered Questions from the »[[OROBOROS_INSTRUMENTS |Oroboros Ecosystem Agenda]]«<br />
</big><br />
<br />
__TOC__<br />
== Mar 2024 ==<br />
* '''Mar-21 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' How well do you handle your Hamilton syringes? What is a cleaning cycle?'''<br><br />
"A syringe cleaning cycle consists of (1) filling an empty syringe with a washing solution while immersing [both the needle and] the base of the barrel into the washing solution, without fully removing the plunger, and (2) emptying the syringe into the waste beaker." <br><br />
- »'''[[MiPNet19.14 SOP Hamilton microsyringes]]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
----<br />
<br />
* '''Mar-20 We''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' What if ''Alert: Error in titrations!'' appears in your O2 analysis template file? '''<br><br />
The O2 analysis template recognizes discrepancies between the protocol selected in the first tab and the imported marks. Check the titration sequence and mark names against the protocol copied from the DLD file.<br><br />
- »'''[[MiPNet24.06 Oxygen flux analysis - DatLab 7.4|O<sub>2</sub> flux analysis]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Mar-07 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Which medium can be used for the instrumental background test?'''<br><br />
When using dithionite, the instrumental background test should be performed in mitochondrial respiration medium MiR05, MiR05-Kit or MiR06; or alternatively, in a strong alkaline phosphate buffer (>100 mM; >pH 8), to avoid side reactions that might interfere with the test.<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background]]'''«<br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
----<br />
<br />
* '''Mar-04 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test? '''<br><br />
Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.<br />
<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
== Feb 2024 ==<br />
* '''Feb-22 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''What to do if the glass of the O2k-chamber starts to become opaque?'''<br><br />
"Turbidity on the glass wall may be caused by precipitated protein. Remove the chambers from the O2k and with the O2k-stirrers removed, immerse in a beaker filled with HCl (10 M) overnight under a hood." <br><br />
-»'''[[MiPNet19.03_O2k-cleaning_and_ISS]]'''«<br><br />
- communicated by »[[Cardoso Luiza]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Feb-08 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Can I use the same stock solutions for all reagents for different O2k-chamber volumes?'''<br><br />
"For some reagents, the concentration of the stock solution differs between the 2.0-mL and the 0.5-mL chamber (O2k-sV-Module) to facilitate a precise volume titration."<br><br />
-»'''[[MiPNet09.12 O2k-Titrations]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
== Jan 2024 ==<br />
* '''Jan-25 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''How do I view and change the settings of a measurement/file in DatLab 8?'''<br><br />
"O2k control (active) will always show the settings of the active recording [and allow changes], while O2k info (view) will show the settings of the recorded selected file."<br><br />
<br />
-»'''[[MiPNet28.07 NextGen-O2k Series XB manual]]'''«; »'''[[MiPNet28.08 Oroboros O2k Series J manual]]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
----<br />
* '''Jan-11 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''What are special features of the new SmartPOS (O2k-Series J and NextGen-O2k-Series XB)?'''<br><br />
- "The electrical connections of the SmartPOS are protected thus there is no need to clean them."<br> <br />
- "The serial number of the SmartPOS is automatically recognized by the DatLab 8 software."<br><br />
<br />
»'''[[MiPNet28.10 SmartPOS-service]]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
<br />
* '''Jan-08 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Do you need to export DatLab traces for your publication? '''<br><br />
Save your graph as an editable picture using "Copy to clipboard" in DatLab 7.4 (.wmf) or "Save" in DatLab 8 (.svg).<br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/Copy_to_clipboard Copy to clipboard in DatLab 7]'''«, »'''[https://www.oroboros.at/index.php/product/datlab/ Download DatLab 8]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Oroboros_Ecosystem_Agenda_2024_Archive&diff=246633
Oroboros Ecosystem Agenda 2024 Archive
2024-03-25T07:09:59Z
<p>Tindle Lisa: </p>
<hr />
<div>{{OROBOROS header page name}}<br />
<br />
{{Template:OROBOROS Slogan}}<br />
<br />
::::<big>» [[OROBOROS INSTRUMENTS|Current Oroboros Ecosystem Agenda ]]</big><br />
<br />
__TOC__<br />
<br />
== Last week ==<br />
2024 Week 12<br />
<br />
* '''Mar-18 Mo'''<br />
:::: '''»[[EU-METAHEART MC2 Meeting 2024 Antalya TR]]«''' Mar 18-21<br />
----<br />
* '''Mar-19 Tu''' <br />
:::: '''15:05 [[Gnaiger Erich|Erich Gnaiger]] presenting at [[EU-METAHEART MC2 Meeting 2024 Antalya TR]]''' - ''[[Donnelly_2024_EU-METAHEART_MC2_Meeting |Functional hypoxia in cardiac mitochondria: effects on oxidative phosphorylation, mitochondrial membrane potential, redox state of coenzyme Q, and calcium uptake]]''<br />
<br />
----<br />
* '''Mar-20 We''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' What if ''Alert: Error in titrations!'' appears in your O2 analysis template file? '''<br><br />
The O2 analysis template recognizes discrepancies between the protocol selected in the first tab and the imported marks. Check the titration sequence and mark names against the protocol copied from the DLD file.<br><br />
- »'''[[MiPNet24.06 Oxygen flux analysis - DatLab 7.4|O<sub>2</sub> flux analysis]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Mar-21 Th''' <br />
:::: '''»[[Club17 2024 Innsbruck AT]]«''' <br />
:::: '''17:00 [[Laner Verena|Verena Laner]] presenting at [[Club17 2024 Innsbruck AT]]''' - ''[[Functional Mitochondrial Diagnostics]]''<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' How well do you handle your Hamilton syringes? What is a cleaning cycle?'''<br><br />
"A syringe cleaning cycle consists of (1) filling an empty syringe with a washing solution while immersing [both the needle and] the base of the barrel into the washing solution, without fully removing the plunger, and (2) emptying the syringe into the waste beaker." <br><br />
- »'''[[MiPNet19.14 SOP Hamilton microsyringes]]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
----<br />
* '''Mar-22 Fr'''<br />
----<br />
<br />
<br />
2024 Week 10<br />
<br />
* '''Mar-04 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test? '''<br><br />
Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.<br />
<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
* '''Mar-05 Tu''' <br />
----<br />
* '''Mar-06 We''' <br />
:{|<br />
| width="100" align="center" |[[File:BEC2024.1.jpg|right|150px|link=https://doi.org/10.26124/bec:2024-0001 |Gross 2024 BEC]]<br />
|'''The tale of two “best-friends,” proteins BID & MTCH2, pivotal regulators of the apoptosis and metabolism programs at the mitochondria.''' <br><br />
* Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001<br />
|}<br />
----<br />
* '''Mar-07 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Which medium can be used for the instrumental background test?'''<br><br />
When using dithionite, the instrumental background test should be performed in mitochondrial respiration medium MiR05, MiR05-Kit or MiR06; or alternatively, in a strong alkaline phosphate buffer (>100 mM; >pH 8), to avoid side reactions that might interfere with the test.<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background]]'''«<br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
----<br />
* '''Mar-08 Fr''' <br />
----<br />
<br />
2024 Week 11<br />
<br />
* '''Mar-11 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
----<br />
* '''Mar-12 Tu''' <br />
----<br />
* '''Mar-13 We''' <br />
:{|<br />
| width="100" align="center" |[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''''Rewarded'' Open Access - compensating authors'''<br><br />
Together with the MiP''society'', BEC is raising funds to reward the first 10 papers accepted for publication in BEC in 2024: 600 EUR to attend EBEC2024 and 2-year MiP''membership''.<br />
-»[https://whydonate.com/en/fundraising/BEC Support open access in science]«<br><br />
- »[https://www.bioenergetics-communications.org/index.php/bec/about/submissions Submit a manuscript]«<br />
|}<br />
----<br />
* '''Mar-14 Th'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|} <br />
----<br />
* '''Mar-15 Fr''' <br />
----<br />
<br />
== Feb 2024 ==<br />
2024 Week 06<br />
<br />
* '''Feb-05 Mo'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"We demonstrated deficient platelet mitochondrial respiratory chain functions, oxidative phosphorylation (OXPHOS), and electron transfer (ET) capacity with complex I (CI)-linked substrates, and reduced [...] endogenous platelet coenzyme Q10 (CoQ10) concentration in UC [urothelial carcinoma] patients."''' <br><br />
* Palacka P, Gvozdjáková A, Rausová Z, Kucharská J, Slopovský J, Obertová J, Furka D, Furka S, Singh KK, Sumbalová Z (2021) Platelet mitochondrial bioenergetics reprogramming in patients with urothelial carcinoma. [[Palacka 2021 Int J Mol Sci|»Bioblast link«]]<br />
:from the O2k-Network »[[SK Bratislava Sumbalova Z]]«<br />
|}<br />
----<br />
* '''Feb-06 Tu''' <br />
----<br />
* '''Feb-07 We''' <br />
----<br />
* '''Feb-08 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Can I use the same stock solutions for all reagents for different O2k-chamber volumes?'''<br><br />
For some reagents, the concentration of the stock solution differs between the 2.0-mL and the 0.5-mL chamber (O2k-sV-Module) to facilitate a precise volume titration.<br><br />
-»'''[[MiPNet09.12 O2k-Titrations]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Feb-09 Fr''' <br />
----<br />
* '''Feb-10 Sa'''<br />
[[File:Year of the Dragon.jpg|400px]] [[File:ChineseNewYear2024 Taiwan.jpg|400px]]<br><br />
<br />
2024 Week 07<br />
<br />
* '''Feb-12 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' What is the O<sub>2</sub> solubility factor of the medium (''F''<sub>M</sub>) and why is it important? '''<br><br />
''F''<sub>M</sub> expresses the effect of the salt concentration on oxygen solubility relative to pure water, and varies depending on the temperature and composition of the medium. The correct ''F''<sub>M</sub> needs to be entered in DatLab when performing an air calibration. <br><br />
- »'''[[Oxygen solubility factor]]'''« , »'''[[Oxygen_calibration_-_DatLab#Air_calibration_in_DatLab|Air calibration in DatLab]]'''« <br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Feb-13 Tu''' <br />
----<br />
* '''Feb-14 We''' <br />
----<br />
* '''Feb-15 Th''' - International Childhood Cancer Day<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Deleterious mtDNA mutations contribute significantly to the tumorigenesis of pediatric cancers"''' <br><br />
* Triska P, Kaneva K, Merkurjev D, Sohail N, Falk MJ, Triche TJ Jr, Biegel JA, Gai X (2019) Landscape of germline and somatic mitochondrial DNA mutations in pediatric malignancies. [[Triska 2019 Cancer Res|»Bioblast link«]]<br />
:from the O2k-Network »[[US_PA_Philadelphia_Falk_MJ]]«<br />
|}<br />
----<br />
* '''Feb-16 Fr''' <br />
----<br />
2024 Week 08<br />
<br />
* '''Feb-19 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“We just published this paper on [https://academic.oup.com/biomedgerontology/advance-article/doi/10.1093/gerona/glad283/7502466 SOMMA], possibly one of the largest aging studies involving permeabilized muscle energetics. Couldn't have done it without the training your teams provided.”'''''<br><br />
'''[[Kramer Philip A]]''' from the O2k-Network Lab »[[US NC Winston-Salem Kramer PA]]«<br><br />
- »'''[https://wiki.oroboros.at/index.php/O2k-Feedback#More_O2k-Feedback| O2k-Feedback]'''«<br><br />
|}<br />
----<br />
* '''Feb-20 Tu''' <br />
----<br />
* '''Feb-21 We''' <br />
----<br />
* '''Feb-22 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''What to do if the glass of the O2k-chamber starts to become opaque?'''<br><br />
"Turbidity on the glass wall may be caused by precipitated protein. Remove the chambers from the O2k and with the O2k-stirrers removed, immerse in a beaker filled with HCl (10 M) overnight under a hood." <br><br />
-»'''[[MiPNet19.03_O2k-cleaning_and_ISS]]'''«<br><br />
- communicated by »[[Cardoso Luiza]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Feb-23 Fr''' <br />
----<br />
2024 Week 09<br />
<br />
* '''Feb-26 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' ATP synthase = phosphorylation system? '''<br><br />
No, the phosphorylation system consists of adenine nucleotide translocase, phosphate carrier, and ATP synthase, which carry out the steps in the phosphorylation pathway. <br><br />
- »'''[[Phosphorylation pathway]]'''«, »'''[https://www.bioblast.at/index.php/Gnaiger_2020_BEC_MitoPathways Mitochondrial Pathways: Chapter 2.2]'''« <br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Feb-27 Tu''' <br />
----<br />
* '''Feb-28 We''' <br />
----<br />
* '''Feb-29 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Bed rest results in a decrease in skeletal muscle mitochondrial respiratory capacity, mainly as a result of an observed decrease in mitochondrial content"''' <br><br />
* Noone J, Damiot A, Kenny H, Chery I, Zahariev A, Normand S, Crampes F, de Glisezinski I, Rochfort KD, Laurens C, Bareille MP, Simon C, Bergouignan A, Blanc S, O'Gorman DJ (2023) The impact of 60 days of -6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics. [[Noone 2023 J Physiol|»Bioblast link«]]<br />
:from the O2k-Networks »[[US FL Orlando Goodpaster BH]]« , »[[FR Strasbourg Blanc S]]« , »[[IE Dublin O Gorman D]]«<br />
|}<br />
----<br />
* '''Mar-01 Fr''' <br />
----<br />
<br />
== Jan 2024 ==<br />
2024 Week 01<br />
* '''Jan-01 Mo'''<br />
----<br />
* '''Jan-02 Tu'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' New year, new state? What is REN state? '''<br><br />
REN state is now distinguished from ROX state: REN is measured in mitochondrial preparations without addition of substrates, whereas ROX is due to oxidative side reactions remaining after inhibition of the electron transfer pathway. <br> <br />
- »'''[[Residual endogenous substrates|REN]]'''«, »'''[[Residual oxygen consumption|ROX]]'''« <br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]« <br />
|} <br />
----<br />
* '''Jan-03 We''' <br />
----<br />
* '''Jan-04 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Oxygen Consumption Rate (OCR) measurements of fresh and cryopreserved placental specimens are comparable whereas snap frozen procedure impairs mitochondrial activity"''' <br><br />
* Giovarelli M, Serati A, Zecchini S, Guelfi F, Clementi E, Mandò C (2023) Cryopreserved placental biopsies maintain mitochondrial activity for high-resolution respirometry. [[Giovarelli 2023 Mol Med|»Bioblast link«]]<br />
:from the O2k-Network »[[IT Milan Clementi E]]«<br />
|}<br />
----<br />
* '''Jan-05 Fr'''<br />
-----<br />
2024 Week 02<br />
<br />
* '''Jan-08 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Do you need to export DatLab traces for your publication? '''<br><br />
Save your graph as an editable picture using "Copy to clipboard" in DatLab 7.4 (.wmf) or "Save" in DatLab 8 (.svg).<br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/Copy_to_clipboard Copy to clipboard in DatLab 7]'''«, »'''[https://www.oroboros.at/index.php/product/datlab/ Download DatLab 8]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
----<br />
* '''Jan-09 Tu''' <br />
----<br />
* '''Jan-10 We'''<br />
:::: '''»[[AICBC 2024 Navi Mumbai IN]]«''' Jan 10-12<br />
----<br />
* '''Jan-11 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''What are special features of the new SmartPOS (O2k-Series J and NextGen-O2k-Series XB)?'''<br><br />
- "The electrical connections of the SmartPOS are protected thus there is no need to clean them."<br> <br />
- "The serial number of the SmartPOS is automatically recognized by the DatLab 8 software."<br><br />
<br />
»'''[[MiPNet28.10 SmartPOS-service]]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
* '''Jan-12 Fr'''<br />
----<br />
2024 Week 03<br />
<br />
* '''Jan-15 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why electron transfer pathway and not electron transfer chain? '''<br><br />
The term “chain” suggests a linear sequence, however, the convergence of electron flow at the Q-junction indicates a higher degree of complexity, making “pathway” a more fitting descriptor. <br><br />
- »'''[[Electron transfer pathway]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''« <br><br />
- communicated by »[[Leo Elettra]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Jan-16 Tu''' <br />
----<br />
* '''Jan-17 We''' <br />
----<br />
* '''Jan-18 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''The study on rats by Jedlička et al indicates that "...the concept of general pattern of age-dependent decline in mitochondrial oxygen consumption across different organs and tissues could be misleading."''' <br><br />
*Jedlička J, Tůma Z, Razak K, Kunc R, Kala A, Proskauer Pena S, Lerchner T, Ježek K, Kuncová J (2022) Impact of aging on mitochondrial respiration in various organs. [[Jedlicka_2022a_Physiol_Res|»Bioblast link«]]<br />
:from the O2k-Network »[[CZ_Pilsen_Kuncova_J]]«<br />
|}<br />
----<br />
* '''Jan-19 Fr'''<br />
----<br />
2024 Week 04<br />
<br />
* '''Jan-22 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“We are truly glad to have your continued support and partnership.”'''''<br><br />
'''[[Lu Amelia]]''' from the O2k-Network Lab »[[TW Taoyuan Sunpoint]]«<br><br />
- »'''[https://wiki.oroboros.at/index.php/O2k-Feedback#More_O2k-Feedback| O2k-Feedback]'''«<br><br />
|}<br />
----<br />
* '''Jan-23 Tu''' <br />
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* '''Jan-24 We''' <br />
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* '''Jan-25 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''How do I view and change the settings of a measurement/file in DatLab 8?'''<br><br />
"O2k control (active) will always show the settings of the active recording [and allow changes], while O2k info (view) will show the settings of the recorded selected file."<br><br />
<br />
-»'''[[MiPNet28.07 NextGen-O2k Series XB manual]]'''«; »'''[[MiPNet28.08 Oroboros O2k Series J manual]]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
----<br />
* '''Jan-26 Fr''' <br />
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2024 Week 05<br />
* '''Jan-29 Mo'''<br />
:::: '''»[[E-mit Winter School 2024 Brixen IT]]«''' Jan 28 - Feb 02<br />
----<br />
* '''Jan-30 Tu'''<br />
:::: '''16:30 [[Gnaiger Erich|Erich Gnaiger]] presenting at [[E-mit Winter School 2024 Brixen IT]]''' - ''Coupling control and pathway control in mitochondrial high-resolution respirometry''<br />
----<br />
* '''Jan-31 We''' <br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Can the S-pathway O<sub><small>2</small></sub> flux be derived by subtracting N-pathway O<sub><small>2</small></sub> flux from NS-pathway O<sub><small>2</small></sub> flux?'''<br><br />
No, the sum of the O<sub><small>2</small></sub> fluxes measured in the presence of NADH-linked substrates alone and succinate as the single substrate is typically higher than using a combination of all these substrates. This effect is described as incomplete additivity: <br><br />
- »'''[[Additive effect of convergent electron flow]]'''« <br><br />
- communicated by »[[Cardoso Luiza]]« and »[[Grings Mateus]]« <br />
|}<br />
----<br />
* '''Feb-01 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“Doing the entire hands-on module from start to finish was the best for really “cementing” theory and hands-on application together.”'''''<br><br />
[[Cosgrove Richard]] from Eli Lilly Research Labs, on what he liked best on [[IOC162]]<br><br />
- »'''[[O2k-Feedback]]'''«<br><br />
|}<br />
----<br />
* '''Feb-02 Fr''' <br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Next_oroboros_ecosystem_agenda&diff=246632
Template:Next oroboros ecosystem agenda
2024-03-25T07:09:55Z
<p>Tindle Lisa: </p>
<hr />
<div><br />
2024 Week 15<br />
<br />
* '''Apr-08 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Is fatty acid oxidation (FAO) considered as CI- or CII-driven respiration? '''<br><br />
Neither. There is simultaneous electron transfer from FAO into the Q-junction through the electron transferring flavoprotein dehydrogenase complex (CETFDH) and Complex I. <br><br />
- »'''[[Fatty acid oxidation]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''«, »'''[[Gnaiger 2023 MitoFit CII]]'''« <br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Willis Jaime R]]« <br />
|}<br />
----<br />
* '''Apr-09 Tu''' <br />
:::: 10:00 '''[[Gnaiger Erich|Erich Gnaiger]] presenting at [[MOSBRI Consensus Meeting 2024 Rome IT]]''' - ''Quality-controlled high-resolution respirometry: bacterial and clinical applications''<br />
----<br />
* '''Apr-10 We''' <br />
----<br />
* '''Apr-11 Th''' <br />
World Parkinson's Disease Day<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"The markers of mitochondrial biogenesis were consistently affected in PD [Parkinson’s disease] patients group."''' <br><br />
* Kamienieva I, Charzyńska A, Duszyński J, Malińska D, Szczepanowska J (2023) In search for mitochondrial biomarkers of Parkinson's disease: Findings in parkin-mutant human fibroblasts. [[Kamienieva 2023 Biochim Biophys Acta Mol Basis Dis|»Bioblast link«]]<br />
:from the O2k-Network »[[PL Warsaw Szewczyk A]]«<br />
|}<br />
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* '''Apr-12 Fr'''<br />
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2024 Week 16<br />
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* '''Apr-15 Mo''' <br />
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2024 Week 17<br />
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* '''Apr-26 Fr'''<br />
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2024 Week 18<br />
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* '''Apr-29 Mo'''<br />
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* '''May-03 Fr'''<br />
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2024 Week 19<br />
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* '''May-06 Mo'''<br />
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* '''May-07 Tu''' <br />
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* '''May-08 We''' <br />
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* '''May-09 Th''' <br />
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* '''May-10 Fr'''<br />
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2024 Week 20<br />
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* '''May-13 Mo'''<br />
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* '''May-17 Fr'''<br />
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2024 Week 21<br />
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* '''May-24 Fr'''<br />
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2024 Week 22<br />
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* '''May-27 Mo'''<br />
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* '''May-31 Fr'''<br />
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2024 Week 23<br />
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* '''Jun-03 Mo'''<br />
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* '''Jun-05 We''' <br />
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* '''Jun-06 Th''' <br />
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* '''Jun-07 Fr'''<br />
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2024 Week 24<br />
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* '''Jun-10 Mo'''<br />
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* '''Jun-11 Tu''' <br />
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* '''Jun-12 We''' <br />
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* '''Jun-13 Th''' <br />
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* '''Jun-14 Fr'''<br />
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2024 Week 25<br />
<br />
* '''Jun-17 Mo'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
<br />
----<br />
* '''Jun-18 Tu''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-19 We''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-20 Th''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-21 Fr'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
<br />
2024 Week 26<br />
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* '''Jun-24 Mo'''<br />
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* '''Jun-25 Tu''' <br />
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* '''Jun-26 We''' <br />
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* '''Jun-27 Th''' <br />
----<br />
* '''Jun-28 Fr'''<br />
<br />
<br />
2024 Week 27<br />
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* '''Jul-01 Mo'''<br />
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* '''Jul-03 We''' <br />
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* '''Jul-04 Th''' <br />
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* '''Jul-05 Fr'''<br />
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2024 Week 28<br />
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* '''Jul-08 Mo'''<br />
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* '''Jul-12 Fr'''<br />
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2024 Week 29<br />
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* '''Jul-15 Mo'''<br />
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* '''Jul-19 Fr'''<br />
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2024 Week 30<br />
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* '''Jul-22 Mo'''<br />
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* '''Jul-24 We''' <br />
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* '''Jul-25 Th''' <br />
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* '''Jul-26 Fr'''<br />
<br />
2024 Week 31<br />
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* '''Jul-29 Mo'''<br />
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* '''Jul-30 Tu''' <br />
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* '''Jul-31 We''' <br />
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* '''Aug-01 Th''' <br />
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* '''Aug-02 Fr'''<br />
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2024 Week 32<br />
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* '''Aug-05 Mo'''<br />
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* '''Aug-08 Th''' <br />
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* '''Aug-09 Fr'''<br />
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2024 Week 33<br />
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* '''Aug-12 Mo'''<br />
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* '''Aug-13 Tu''' <br />
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* '''Aug-14 We''' <br />
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* '''Aug-15 Th''' <br />
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* '''Aug-16 Fr'''<br />
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2024 Week 34<br />
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* '''Aug-19 Mo'''<br />
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* '''Aug-22 Th''' <br />
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* '''Aug-23 Fr'''<br />
<br />
2024 Week 35<br />
<br />
* '''Aug-26 Mo'''<br />
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* '''Aug-27 Tu''' <br />
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* '''Aug-28 We''' <br />
----<br />
* '''Aug-29 Th''' <br />
----<br />
* '''Aug-30 Fr'''<br />
<br />
2024 Week 36<br />
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* '''Sep-02 Mo'''<br />
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* '''Sep-03 Tu''' <br />
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* '''Sep-04 We''' <br />
----<br />
* '''Sep-05 Th''' <br />
----<br />
* '''Sep-06 Fr'''<br />
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2024 Week 37<br />
<br />
* '''Sep-09 Mo'''<br />
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* '''Sep-10 Tu''' <br />
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* '''Sep-11 We''' <br />
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* '''Sep-12 Th''' <br />
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* '''Sep-13 Fr'''<br />
<br />
2024 Week 38<br />
<br />
* '''Sep-16 Mo'''<br />
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* '''Sep-17 Tu''' <br />
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* '''Sep-18 We''' <br />
----<br />
* '''Sep-19 Th''' <br />
----<br />
* '''Sep-20 Fr'''<br />
<br />
2024 Week 39<br />
<br />
* '''Sep-22 Su'''<br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
* '''Sep-23 Mo'''<br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-24 Tu''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-25 We''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-26 Th''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-27 Fr'''<br />
<br />
<br />
2024 Week 40<br />
<br />
* '''Sep-30 Mo'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-01 Tu''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-02 We''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-03 Th''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-04 Fr'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
<br />
2024 Week 41<br />
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* '''Okt-07 Mo'''<br />
----<br />
* '''Okt-08 Tu''' <br />
----<br />
* '''Okt-09 We''' <br />
----<br />
* '''Okt-10 Th''' <br />
----<br />
* '''Okt-11 Fr'''<br />
<br />
2024 Week 42<br />
<br />
* '''Okt-14 Mo'''<br />
----<br />
* '''Okt-15 Tu''' <br />
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* '''Okt-16 We''' <br />
----<br />
* '''Okt-17 Th''' <br />
----<br />
* '''Okt-18 Fr'''<br />
<br />
2024 Week 43<br />
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* '''Okt-21 Mo'''<br />
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* '''Okt-22 Tu''' <br />
----<br />
* '''Okt-23 We''' <br />
----<br />
* '''Okt-24 Th''' <br />
----<br />
* '''Okt-25 Fr'''<br />
::::: <big> '''[[14th Mitochondrial Disease Conference 2024 Padova IT]]'''</big> 2024 Oct 25-27<br />
<br />
2024 Week 44<br />
<br />
* '''Okt-28 Mo'''<br />
----<br />
* '''Okt-29 Tu''' <br />
----<br />
* '''Okt-30 We''' <br />
----<br />
* '''Okt-31 Th''' <br />
----<br />
* '''Nov-01 Fr''' <br />
<br />
2024 Week 45<br />
<br />
* '''Nov-04 Mo'''<br />
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* '''Nov-05 Tu''' <br />
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* '''Nov-06 We''' <br />
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* '''Nov-07 Th''' <br />
----<br />
* '''Nov-08 Fr'''<br />
<br />
2024 Week 46<br />
<br />
* '''Nov-11 Mo'''<br />
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* '''Nov-12 Tu''' <br />
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* '''Nov-13 We''' <br />
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* '''Nov-14 Th''' <br />
----<br />
* '''Nov-15 Fr'''<br />
<br />
<br />
2024 Week 47<br />
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* '''Nov-18 Mo'''<br />
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* '''Nov-19 Tu''' <br />
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* '''Nov-20 We''' <br />
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* '''Nov-21 Th''' <br />
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* '''Nov-22 Fr'''<br />
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2024 Week 48<br />
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* '''Nov-25 Mo'''<br />
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* '''Nov-26 Tu''' <br />
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* '''Nov-27 We''' <br />
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* '''Nov-28 Th''' <br />
----<br />
* '''Nov-29 Fr'''<br />
<br />
2024 Week 49<br />
<br />
* '''Dez-02 Mo'''<br />
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* '''Dez-03 Tu''' <br />
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* '''Dez-04 We''' <br />
----<br />
* '''Dez-05 Th''' <br />
----<br />
* '''Dez-06 Fr'''<br />
<br />
2024 Week 50<br />
<br />
* '''Dez-09 Mo'''<br />
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* '''Dez-10 Tu''' <br />
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* '''Dez-11 We''' <br />
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* '''Dez-12 Th''' <br />
----<br />
* '''Dez-13 Fr'''<br />
<br />
2024 Week 51<br />
<br />
* '''Dez-16 Mo'''<br />
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* '''Dez-17 Tu''' <br />
----<br />
* '''Dez-18 We''' <br />
----<br />
* '''Dez-19 Th''' <br />
----<br />
* '''Dez-20 Fr'''<br />
<br />
2024 Week 52<br />
<br />
* '''Dez-23 Mo'''<br />
----<br />
* '''Dez-24 Tu''' <br />
----<br />
* '''Dez-25 We''' <br />
----<br />
* '''Dez-26 Th''' <br />
----<br />
* '''Dez-27 Fr'''</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Current_week_ecosystem_agenda&diff=246631
Template:Current week ecosystem agenda
2024-03-25T07:09:50Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:Science for Ukraine}}<br />
<br />
2024 Week 13<br />
<br />
* '''Mar-25 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Living cells or intact cells? '''<br><br />
Living cells are frequently labelled as ''intact cells'' in the sense of the total cell count, but ''intact'' may suggest dual meanings of viable or unaffected by a disease or mitochondrial injury. <br><br />
- »'''[[Living cells]]'''«, »'''[[BEC 2020.1]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''« <br><br />
- communicated by »[[Leo Elettra]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Mar-26 Tu''' <br />
----<br />
* '''Mar-27 We''' <br />
----<br />
* '''Mar-28 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''"Introduction to the new models available with the NextGen was immensely helpful. This [[MiPNet28.02_IOC162_Schroecken_AT|workshop]] has been critical for implementation of new techniques and advancement of my research."'''''<br><br />
[[Zunica Elizabeth]], from the O2k-Network »[[US LA Baton Rouge Noland RC]]«<br><br />
- »'''[[O2k-Feedback]]'''«<br><br />
|}<br />
----<br />
* '''Mar-29 Fr'''<br />
----<br />
'''<big>Next Week</big>'''<br />
2024 Week 14<br />
<br />
* '''Apr-01 Mo'''<br />
April - Parkinson's Awareness Month <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Although the chain of events leading to this respiration deficit is currently not understood, the findings constitute a robust assay for the progressive pathology induced by PINK1 deficiency.''' <br><br />
* Gispert S, Ricciardi F, Kurz A, Azizov M, Hoepken HH, Becker D, Voos W, Leuner K, Müller WE, Kudin AP, Kunz WS, Zimmermann A, Roeper J, Wenzel D, Jendrach M, García-Arencíbia M, Fernández-Ruiz J, Huber L, Rohrer H, Barrera M, Reichert AS, Rüb U, Chen A, Nussbaum RL, Auburger G (2009) Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration. [[Gispert 2009 PLoS One|»Bioblast link«]]<br />
:from the O2k-Network »[[US CA San Francisco Nussbaum RL]]« and »[[DE Frankfurt Eckert GP]]«<br />
|} <br />
----<br />
* '''Apr-02 Tu''' <br />
----<br />
* '''Apr-03 We''' <br />
----<br />
* '''Apr-04 Th''' <br />
----<br />
* '''Apr-05 Fr'''<br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=MiPNet28.13_IOC165_Innsbruck_AT&diff=246518
MiPNet28.13 IOC165 Innsbruck AT
2024-03-14T17:37:09Z
<p>Tindle Lisa: </p>
<hr />
<div>{{OROBOROS header page name}}<br />
{{Publication<br />
|title=[[Image:O2k-Workshops.png|right|80px|link=O2k-Workshops]]'''Schroecken AT''', 2024 Sep 02-04. EBEC2024 Satellite Oroboros O2k-Workshop: Mito&Chlora High-Resolution Respirometry and PhotoBiology, '''IOC165'''.<br />
|authors=Oroboros<br />
|year=2024-09-02<br />
|journal=Mitochondr Physiol Network<br />
|abstract='''EBEC2024 Satellite Oroboros O2k-Workshop: Mito&Chlora High-Resolution Respirometry and PhotoBiology'''. Innsbruck, Austria (2024 Sep 02-04).<br><br />
|mipnetlab=AT_Innsbruck_Oroboros<br />
}}<br />
<br />
__TOC__<br />
== General information ==<br />
:::: This 2.5-day training course provides an introduction the Oroboros [[O2k-FluoRespirometer]] including the [[PB-Module|O2k-PB-Module]], [[DatLab]] 8 and applications of the [[TIP2k-Module|TIP2k]]. Hands-on experiments illustrate the principle and show the unique advantages and limitations of simultaneous monitoring of oxygen concentration, mitochondrial respiration and hydrogen peroxide production. Many optimized [[SUIT protocols]] are available as DL-Protocols. The [[SUITbrowser]] helps you find the best SUIT protocol for your specific research questions. Furthermore, this workshop covers interpretation as well as calibration and instrumental service.<br />
<br />
<br />
== Venue ==<br />
::::» Oroboros O2k-Laboratory and ''MiPArt''<br />
::::: Schoepfstrasse 18, 6020 Innsbruck<br />
::::» Information on travel and venue: '''[[IOC Innsbruck]]'''<br />
<br />
<br />
== Registration ==<br />
:::: Registration will open soon.<br />
<br />
== Program ==<br />
:::: A new program is being created and will be uploaded when finalized. <br />
<br><br />
<br />
=== Tutors and lecturers ===<br />
<gallery mode=default perrow=6 widths="140px" heights="150px"><br />
File:Erich Gnaiger.jpg|'''[[Gnaiger E |Erich Gnaiger]]''', PhD, Oroboros Instruments - CEO, ''Innovation Alchemist''<br />
</gallery><br />
<br />
=== Participants ===<br />
<br />
{| class="wikitable"<br />
|-<br />
!<br />
!<br />
! Participant<br />
! Institution<br />
|-<br />
|1.<br />
|-<br />
|}<br />
<br />
<br />
<br />
<br />
<br />
<br />
== Contact ==<br />
:::: [mailto:instruments@oroboros.at| instruments@oroboros.at]<br />
<br />
:::: '''Oroboros Instruments'''<br />
:::: High-Resolution Respirometry <br />
:::: Schoepfstrasse 18<br />
:::: A-6020 Innsbruck, Austria<br />
:::: Tel: +43 677 647 929 17<br />
:::: Fax: +43 512 566796 20 <br />
<br />
:::: '''Mitochondria and Cell Research'''<br />
<br />
<br />
== IOC recommended reading ==<br />
::::» '''[[IOC recommended reading]]'''<br />
::::» '''[[MitoPedia: Respiratory states]]'''<br />
:::: [[Image:P.jpg|link=OXPHOS capacity|35px|OXPHOS]] [[Image:R.jpg|link=ROUTINE respiration|35px|ROUTINE]] [[Image:E.jpg|link=ET capacity|35px|ETS]] [[Image:L.jpg|link=LEAK respiration|35px|LEAK]] [[Image:ROX.jpg|link=Residual oxygen consumption|65px|ROX]]<br />
<br />
<br />
[[Image:MitoGlobal.jpg|right|80px|link=MitoGlobal|MitoGlobal]] <br />
O2k-Workshops are listed as [[MitoGlobal Events]].<br />
<br />
<br />
{{Labeling<br />
|additional=ORO, IOC, MitoFit, 2024, MitoGlobal, NextGen-O2k, Next, O2k-Network Award,<br />
}}<br />
<br />
[[Category:O2k-Workshops]]</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=MiPNet28.13_IOC165_Innsbruck_AT&diff=246517
MiPNet28.13 IOC165 Innsbruck AT
2024-03-14T16:35:38Z
<p>Tindle Lisa: Created page with "{{OROBOROS header page name}} {{Publication |title=link=O2k-Workshops'''Schroecken AT''', 2024 Sep 02-04. EBEC2024 Satellite Oroboros O2..."</p>
<hr />
<div>{{OROBOROS header page name}}<br />
{{Publication<br />
|title=[[Image:O2k-Workshops.png|right|80px|link=O2k-Workshops]]'''Schroecken AT''', 2024 Sep 02-04. EBEC2024 Satellite Oroboros O2k-Workshop: Mito&Chlora High-Resolution Respirometry and PhotoBiology, '''IOC165'''.<br />
|authors=Oroboros<br />
|year=2024-09-02<br />
|journal=Mitochondr Physiol Network<br />
|abstract='''EBEC2024 Satellite Oroboros O2k-Workshop: Mito&Chlora High-Resolution Respirometry and PhotoBiology'''. Innsbruck, Austria (2024 Sep 02-04).<br><br />
|mipnetlab=AT_Innsbruck_Oroboros<br />
}}<br />
<br />
__TOC__<br />
== General information ==<br />
:::: This 2.5-day training course provides an introduction the Oroboros [[O2k-FluoRespirometer]] inlcuding the [[PB-Module|O2k-PB-Module]], [[DatLab]] 8 and applications of the [[TIP2k-Module|TIP2k]]. Hands-on experiments illustrate the principle and show the unique advantages and limitations of simultaneous monitoring of oxygen concentration, mitochondrial respiration and hydrogen peroxide production. Many optimized [[SUIT protocols]] are available as DL-Protocols. The [[SUITbrowser]] helps you find the best SUIT protocol for your specific research questions. Furthermore, this workshop covers interpretation as well as calibration and instrumental service.<br />
<br />
<br />
== Venue ==<br />
::::» Oroboros O2k-Laboratory and ''MiPArt''<br />
::::: Schoepfstrasse 18, 6020 Innsbruck<br />
::::» Information on travel and venue: '''[[IOC Innsbruck]]'''<br />
<br />
<br />
== Registration ==<br />
:::: Registration will open soon.<br />
<br />
== Program ==<br />
:::: A new program is being created and will be uploaded when finalized. <br />
<br><br />
<br />
=== Tutors and lecturers ===<br />
<gallery mode=default perrow=6 widths="140px" heights="150px"><br />
File:Erich Gnaiger.jpg|'''[[Gnaiger E |Erich Gnaiger]]''', PhD, Oroboros Instruments - CEO, ''Innovation Alchemist''<br />
</gallery><br />
<br />
=== Participants ===<br />
<br />
{| class="wikitable"<br />
|-<br />
!<br />
!<br />
! Participant<br />
! Institution<br />
|-<br />
|1.<br />
|-<br />
|}<br />
<br />
<br />
<br />
<br />
<br />
<br />
== Contact ==<br />
:::: [mailto:instruments@oroboros.at| instruments@oroboros.at]<br />
<br />
:::: '''Oroboros Instruments'''<br />
:::: High-Resolution Respirometry <br />
:::: Schoepfstrasse 18<br />
:::: A-6020 Innsbruck, Austria<br />
:::: Tel: +43 677 647 929 17<br />
:::: Fax: +43 512 566796 20 <br />
<br />
:::: '''Mitochondria and Cell Research'''<br />
<br />
<br />
== IOC recommended reading ==<br />
::::» '''[[IOC recommended reading]]'''<br />
::::» '''[[MitoPedia: Respiratory states]]'''<br />
:::: [[Image:P.jpg|link=OXPHOS capacity|35px|OXPHOS]] [[Image:R.jpg|link=ROUTINE respiration|35px|ROUTINE]] [[Image:E.jpg|link=ET capacity|35px|ETS]] [[Image:L.jpg|link=LEAK respiration|35px|LEAK]] [[Image:ROX.jpg|link=Residual oxygen consumption|65px|ROX]]<br />
<br />
<br />
[[Image:MitoGlobal.jpg|right|80px|link=MitoGlobal|MitoGlobal]] <br />
O2k-Workshops are listed as [[MitoGlobal Events]].<br />
<br />
<br />
{{Labeling<br />
|additional=ORO, IOC, MitoFit, 2024, MitoGlobal, NextGen-O2k, Next, O2k-Network Award,<br />
}}<br />
<br />
[[Category:O2k-Workshops]]</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Installation_and_startup_support_session_self-study_material&diff=246512
Installation and startup support session self-study material
2024-03-14T08:41:57Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Technical support}}<br />
__TOC__<br />
<br />
== General information == <br />
:::: To benefit optimally from the remote installation ans startup training sessions, please make yourself familiar with '''Materials for self-study''' in advance.<br />
<br />
== Program ==<br />
::::» [[File:PDF.jpg|100px|link=https://wiki.oroboros.at/images/6/6e/MiPNet26.07_Installation_and_startup_support_session_program.pdf|Bioblast pdf]] <br />
<br />
== Materials for self-study ==<br />
<br />
=== Part 1.1: OroboPOS service and O2k instrumental set up ===<br />
<br />
:::* [[MiPNet28.07 NextGen-O2k Series XB manual|O2k-Manual: NextGen-O2k Series XB]] OR [[MiPNet28.08 Oroboros O2k Series J manual|O2k-Manual: Oroboros O2k Series J]]<br />
:::* [[MiPNet28.10 SmartPOS-service|O2k-Manual: SmartPOS-service]] <br />
:::* Step 1: [https://www.youtube.com/watch?v=wMDcSypG3O4&feature=youtu.be O2k-Videosupport: OroboPOS] <br />
:::* Step 2: [https://www.youtube.com/watch?v=HC6MLXO08k8&feature=youtu.be O2k-Videosupport: Cathode cleaning] <br />
:::* Step 3: [https://www.youtube.com/watch?v=sDoU69-SLq0&feature=youtu.be O2k-Videosupport: Anode cleaning] <br />
:::* Step 4: [https://www.youtube.com/watch?v=iGafaPa4OyA&feature=youtu.be O2k-Videosupport: Membrane mounting] <br />
:::* Step 5: [https://www.youtube.com/watch?v=0EfCReolzdk&list=PLT4umseflf-m6O1sApyn9doi8vHNAKaIs&index=6 O2k-Videosupport: Start DatLab 7] (For O2k-Series A to I)<br />
:::* Step 6: [https://www.youtube.com/watch?v=pGzb0KfYwTQ&feature=youtu.be O2k-Videosupport: Insert OroboPOS] <br />
:::* Step 7: [https://www.youtube.com/watch?v=1MSsI1ePMu8&feature=youtu.be O2k-Videosupport: Insert O2k Chamber] <br />
:::* Step 8: [https://www.youtube.com/watch?v=DuaEJc7FBjk&feature=youtu.be O2k-Videosupport: O2k Chamber volume calibration] <br />
<br />
=== Part 1.2: DatLab ===<br />
:::* [[MitoPedia: DatLab]] <br />
:::* [[Run DL-Protocol/Set O2 limit|DL-Protocols]]<br />
<br />
=== Part 2: O<sub>2</sub> calibration and instrumental background ===<br />
<br />
:::* [[Gnaiger 2008 POS]] <br />
:::* [[MiPNet19.03 O2k-cleaning and ISS|SOP: O2k-cleaning and ISS]] <br />
:::* [[MiPNet06.03 POS-calibration-SOP|SOP: O<sub>2</sub>-calibration]] <br />
:::* [https://www.youtube.com/watch?v=onOIVpmOEoE O2k-Videosupport: QC1: POS calibration]<br />
:::* [[MiPNet14.06 Instrumental O2 background|SOP: O<sub>2</sub> background]]</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Current_week_ecosystem_agenda&diff=246484
Template:Current week ecosystem agenda
2024-03-13T11:49:27Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:Science for Ukraine}}<br />
2024 Week 11<br />
<br />
* '''Mar-11 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
----<br />
* '''Mar-12 Tu''' <br />
----<br />
* '''Mar-13 We''' <br />
:{|<br />
| width="100" align="center" |[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''''Rewarded'' Open Access - compensating authors'''<br><br />
Together with the MiP''society'', BEC is raising funds to reward the first 10 papers accepted for publication in BEC in 2024: 600 EUR to attend EBEC2024 and 2-year MiP''membership''.<br />
-»[https://whydonate.com/en/fundraising/BEC Support open access in science]«<br><br />
- »[https://www.bioenergetics-communications.org/index.php/bec/about/submissions Submit a manuscript]«<br />
|}<br />
----<br />
* '''Mar-14 Th'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|} <br />
----<br />
* '''Mar-15 Fr''' <br />
----<br />
<br />
'''<big>Next Week</big>'''<br />
2024 Week 12<br />
<br />
* '''Mar-18 Mo'''<br />
::::: '''[[EU-METAHEART MC2 Meeting 2024 Antalya TR]]''' Mar 18-21<br />
----<br />
* '''Mar-19 Tu''' <br />
:::: 15:05 '''[[Gnaiger Erich|Erich Gnaiger]] presenting at [[EU-METAHEART MC2 Meeting 2024 Antalya TR]]''' - ''[[Donnelly_2024_EU-METAHEART_MC2_Meeting |Impact of hypoxia on mitochondrial function]]''<br />
<br />
----<br />
* '''Mar-20 We''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' What if ''Alert: Error in titrations!'' appears in your O2 analysis template file? '''<br><br />
The O2 analysis template recognizes discrepancies between the protocol selected in the first tab and the imported marks. Check the titration sequence and mark names against the protocol copied from the DLD file.<br><br />
- »'''[[MiPNet24.06 Oxygen flux analysis - DatLab 7.4|O<sub>2</sub> flux analysis]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Mar-21 Th''' <br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' How well do you handle your Hamilton syringes? What is a cleaning cycle?'''<br><br />
"A syringe cleaning cycle consists of (1) filling an empty syringe with a washing solution while immersing [both the needle and] the base of the barrel into the washing solution, without fully removing the plunger, and (2) emptying the syringe into the waste beaker." <br><br />
- »'''[[MiPNet19.14 SOP Hamilton microsyringes]]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
----<br />
* '''Mar-22 Fr'''<br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Current_week_ecosystem_agenda&diff=246483
Template:Current week ecosystem agenda
2024-03-13T11:42:36Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:Science for Ukraine}}<br />
2024 Week 11<br />
<br />
* '''Mar-11 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
----<br />
* '''Mar-12 Tu''' <br />
----<br />
* '''Mar-13 We''' <br />
:{|<br />
| width="100" align="center" |[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''''Rewarded'' Open Access - compensating authors'''<br><br />
Together with the MiP''society'', BEC is raising funds to reward the first 10 papers accepted for publication in BEC in 2024: 600 EUR to attend EBEC2024 and 2-year MiP''membership''.<br />
-»[https://whydonate.com/en/fundraising/BEC Support open access in science]«<br><br />
- »[https://www.bioenergetics-communications.org/index.php/bec/about/submissions Submit a manuscript]«<br />
|}<br />
----<br />
* '''Mar-14 Th'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|} <br />
----<br />
* '''Mar-15 Fr''' <br />
----<br />
<br />
'''<big>Next Week</big>'''<br />
2024 Week 12<br />
<br />
* '''Mar-18 Mo'''<br />
::::: '''[[EU-METAHEART MC2 Meeting 2024 Antalya TR]]''' Mar 18-21<br />
----<br />
* '''Mar-19 Tu''' <br />
:::: 15:05 '''[[Gnaiger Erich|Erich Gnaiger]] presenting at [[EU-METAHEART MC2 Meeting 2024 Antalya TR]]''' - ''[[Donnelly_2024_EU-METAHEART_MC2_Meeting |Impact of hypoxia on mitochondrial function]]''<br />
<br />
----<br />
* '''Mar-20 We''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' What if ''Alert: Error in titrations!'' appears in your O2 analysis template file? '''<br><br />
The O2 analysis template recognizes discrepancies between the protocol selected in the first tab and the imported marks. Check the titration sequence and mark names against the protocol copied from the DLD file.<br><br />
- »'''[[MiPNet24.06 Oxygen flux analysis - DatLab 7.4|O<sub>2</sub> flux analysis]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Mar-21 Th''' <br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' How well do you handle your Hamilton syringes? What is a cleaning cycle?'''<br><br />
"A syringe cleaning cycle consists of filling an empty syringe with a washing solution while immersing [...] also the base of the barrel into the washing solution, without fully removing the plunger, and emptying the syringe into the waste beaker". <br><br />
- »'''[[MiPNet19.14 SOP Hamilton microsyringes]]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
----<br />
* '''Mar-22 Fr'''<br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=MOSBRI_Consensus_Meeting_2024_Rome_IT&diff=246482
MOSBRI Consensus Meeting 2024 Rome IT
2024-03-13T11:35:38Z
<p>Tindle Lisa: </p>
<hr />
<div>{{MitoGlobal header page name}}<br />
<br />
{{Publication<br />
|title='''Rome IT''', 2024 Apr 09. MOSBRI Consensus Meeting - Real-time monitoring using biophysical approaches of respiratory activity in bacteria<br />
|info= [https://www.mosbri.eu/events/meetings/cm-april2024/ Conference website]<br />
|authors= MOSBRI<br />
|year=2024-04-09<br />
|journal=MitoGlobal<br />
|abstract= MOSBRI Consensus Meeting, Rome, IT, 2024<br />
}}<br />
<br />
== General information==<br />
:::: This consensus meeting aims to outline and define novel frontiers of the real-time techniques for monitoring respiratory and metabolic activities in bacteria, using biophysical methods.<br />
:::: Through a series of talks featuring expert speakers and a roundtable discussion, the event will combine expertise from manufacturers alongside academia. The primary objective is to define, project, and establish benchmarks for these monitoring techniques.<br />
:::: While the applications span diverse domains such as physiopathologic analysis and antimicrobial identification, critical questions remain open. These encompass the precision of real-time monitoring, its scalability across bacterial species, and the translation of laboratory findings into clinical or industrial settings.<br />
<br />
== Venue ==<br />
:::: Online and in person at:<br />
:::: Sapienza University of Rome<br />
:::: Viale Regina Elena, 295B/Edificio D<br />
:::: 00161 Rome<br />
:::: Italy<br />
<br />
== Program ==<br />
:::: The program is available [https://wiki.oroboros.at/images/7/7e/MOSBRI_Consensus_meeting_program.pdf here]<br />
<br />
== Registration ==<br />
:::: Deadline for registration: 28th March 2024<br />
:::: [https://forms.gle/Djdx1M79hQZq163M9 Registration form]<br />
<br />
== Oroboros at MOSBRI Consensus Meeting ==<br />
:::: '''[[Gnaiger Erich|Erich Gnaiger]]''': Quality-controlled high-resolution respirometry: bacterial and clinical applications ''10:00''<br />
<br />
<br />
{{Labeling<br />
|additional=2024, MitoGlobal, ORO, Next<br />
}}<br />
<br />
<br />
[[Image:MitoGlobal.jpg|right|80px|link=http://www.bioblast.at/index.php/MitoGlobal|MitoGlobal]] <br />
Listed under [[MitoGlobal Events]].</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Next_oroboros_ecosystem_agenda&diff=246481
Template:Next oroboros ecosystem agenda
2024-03-13T11:28:48Z
<p>Tindle Lisa: </p>
<hr />
<div><br />
2024 Week 13<br />
<br />
* '''Mar-25 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Living cells or intact cells? '''<br><br />
Living cells are frequently labelled as ''intact cells'' in the sense of the total cell count, but ''intact'' may suggest dual meanings of viable or unaffected by a disease or mitochondrial injury. <br><br />
- »'''[[Living cells]]'''«, »'''[[BEC 2020.1]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''« <br><br />
- communicated by »[[Leo Elettra]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Mar-26 Tu''' <br />
----<br />
* '''Mar-27 We''' <br />
----<br />
* '''Mar-28 Th''' <br />
----<br />
* '''Mar-29 Fr'''<br />
<br />
<br />
2024 Week 14<br />
<br />
* '''Apr-01 Mo''' <br />
----<br />
* '''Apr-02 Tu''' <br />
----<br />
* '''Apr-03 We''' <br />
----<br />
* '''Apr-04 Th''' <br />
----<br />
* '''Apr-05 Fr'''<br />
<br />
2024 Week 15<br />
<br />
* '''Apr-08 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Is fatty acid oxidation (FAO) considered as CI- or CII-driven respiration? '''<br><br />
Neither. FAO generates acetyl-coA, which will enter the TCA cycle, and FADH<sub>2</sub>, resulting in simultaneous electron transfer into the Q-junction through the electron transferring flavoprotein complex (CETF) and Complex I. <br><br />
- »'''[[Fatty acid oxidation]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''«, »'''[[Gnaiger 2023 MitoFit CII]]'''« <br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Willis Jaime R]]« <br />
|}<br />
----<br />
* '''Apr-09 Tu''' <br />
:::: 10:00 '''[[Gnaiger Erich|Erich Gnaiger]] presenting at [[MOSBRI Consensus Meeting 2024 Rome IT]]''' - ''Quality-controlled high-resolution respirometry: bacterial and clinical applications''<br />
----<br />
* '''Apr-10 We''' <br />
----<br />
* '''Apr-11 Th''' <br />
----<br />
* '''Apr-12 Fr'''<br />
<br />
2024 Week 16<br />
<br />
* '''Apr-15 Mo''' <br />
----<br />
* '''Apr-16 Tu''' <br />
----<br />
* '''Apr-17 We''' <br />
----<br />
* '''Apr-18 Th''' <br />
----<br />
* '''Apr-19 Fr'''<br />
<br />
2024 Week 17<br />
<br />
* '''Apr-22 Mo'''<br />
----<br />
* '''Apr-23 Tu''' <br />
----<br />
* '''Apr-24 We''' <br />
----<br />
* '''Apr-25 Th''' <br />
----<br />
* '''Apr-26 Fr'''<br />
<br />
2024 Week 18<br />
<br />
* '''Apr-29 Mo'''<br />
----<br />
* '''Apr-30 Tu''' <br />
----<br />
* '''May-01 We''' <br />
----<br />
* '''May-02 Th''' <br />
----<br />
* '''May-03 Fr'''<br />
<br />
2024 Week 19<br />
<br />
* '''May-06 Mo'''<br />
----<br />
* '''May-07 Tu''' <br />
----<br />
* '''May-08 We''' <br />
----<br />
* '''May-09 Th''' <br />
----<br />
* '''May-10 Fr'''<br />
<br />
2024 Week 20<br />
<br />
* '''May-13 Mo'''<br />
----<br />
* '''May-14 Tu''' <br />
----<br />
* '''May-15 We''' <br />
----<br />
* '''May-16 Th''' <br />
----<br />
* '''May-17 Fr'''<br />
<br />
2024 Week 21<br />
<br />
* '''May-20 Mo''' <br />
----<br />
* ''May-21 Tu''' <br />
----<br />
* '''May-22 We''' <br />
----<br />
* '''May-23 Th''' <br />
----<br />
* '''May-24 Fr'''<br />
<br />
2024 Week 22<br />
<br />
* '''May-27 Mo'''<br />
----<br />
* '''May-28 Tu''' <br />
----<br />
* '''May-29 We''' <br />
----<br />
* '''May-30 Th''' <br />
----<br />
* '''May-31 Fr'''<br />
<br />
2024 Week 23<br />
<br />
* '''Jun-03 Mo'''<br />
----<br />
* '''Jun-04 Tu''' <br />
----<br />
* '''Jun-05 We''' <br />
----<br />
* '''Jun-06 Th''' <br />
----<br />
* '''Jun-07 Fr'''<br />
<br />
2024 Week 24<br />
<br />
* '''Jun-10 Mo'''<br />
----<br />
* '''Jun-11 Tu''' <br />
----<br />
* '''Jun-12 We''' <br />
----<br />
* '''Jun-13 Th''' <br />
----<br />
* '''Jun-14 Fr'''<br />
<br />
2024 Week 25<br />
<br />
* '''Jun-17 Mo'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
<br />
----<br />
* '''Jun-18 Tu''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-19 We''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-20 Th''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-21 Fr'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
<br />
2024 Week 26<br />
<br />
* '''Jun-24 Mo'''<br />
----<br />
* '''Jun-25 Tu''' <br />
----<br />
* '''Jun-26 We''' <br />
----<br />
* '''Jun-27 Th''' <br />
----<br />
* '''Jun-28 Fr'''<br />
<br />
<br />
2024 Week 27<br />
<br />
* '''Jul-01 Mo'''<br />
----<br />
* '''Jul-02 Tu''' <br />
----<br />
* '''Jul-03 We''' <br />
----<br />
* '''Jul-04 Th''' <br />
----<br />
* '''Jul-05 Fr'''<br />
<br />
2024 Week 28<br />
<br />
* '''Jul-08 Mo'''<br />
----<br />
* '''Jul-09 Tu''' <br />
----<br />
* '''Jul-10 We''' <br />
----<br />
* '''Jul-11 Th''' <br />
----<br />
* '''Jul-12 Fr'''<br />
<br />
2024 Week 29<br />
<br />
* '''Jul-15 Mo'''<br />
----<br />
* '''Jul-16 Tu''' <br />
----<br />
* '''Jul-17 We''' <br />
----<br />
* '''Jul-18 Th''' <br />
----<br />
* '''Jul-19 Fr'''<br />
<br />
2024 Week 30<br />
<br />
* '''Jul-22 Mo'''<br />
----<br />
* '''Jul-23 Tu''' <br />
----<br />
* '''Jul-24 We''' <br />
----<br />
* '''Jul-25 Th''' <br />
----<br />
* '''Jul-26 Fr'''<br />
<br />
2024 Week 31<br />
<br />
* '''Jul-29 Mo'''<br />
----<br />
* '''Jul-30 Tu''' <br />
----<br />
* '''Jul-31 We''' <br />
----<br />
* '''Aug-01 Th''' <br />
----<br />
* '''Aug-02 Fr'''<br />
<br />
2024 Week 32<br />
<br />
* '''Aug-05 Mo'''<br />
----<br />
* '''Aug-06 Tu''' <br />
----<br />
* '''Aug-07 We''' <br />
----<br />
* '''Aug-08 Th''' <br />
----<br />
* '''Aug-09 Fr'''<br />
<br />
2024 Week 33<br />
<br />
* '''Aug-12 Mo'''<br />
----<br />
* '''Aug-13 Tu''' <br />
----<br />
* '''Aug-14 We''' <br />
----<br />
* '''Aug-15 Th''' <br />
----<br />
* '''Aug-16 Fr'''<br />
<br />
2024 Week 34<br />
<br />
* '''Aug-19 Mo'''<br />
----<br />
* '''Aug-20 Tu''' <br />
----<br />
* '''Aug-21 We''' <br />
----<br />
* '''Aug-22 Th''' <br />
----<br />
* '''Aug-23 Fr'''<br />
<br />
2024 Week 35<br />
<br />
* '''Aug-26 Mo'''<br />
----<br />
* '''Aug-27 Tu''' <br />
----<br />
* '''Aug-28 We''' <br />
----<br />
* '''Aug-29 Th''' <br />
----<br />
* '''Aug-30 Fr'''<br />
<br />
2024 Week 36<br />
<br />
* '''Sep-02 Mo'''<br />
----<br />
* '''Sep-03 Tu''' <br />
----<br />
* '''Sep-04 We''' <br />
----<br />
* '''Sep-05 Th''' <br />
----<br />
* '''Sep-06 Fr'''<br />
<br />
2024 Week 37<br />
<br />
* '''Sep-09 Mo'''<br />
----<br />
* '''Sep-10 Tu''' <br />
----<br />
* '''Sep-11 We''' <br />
----<br />
* '''Sep-12 Th''' <br />
----<br />
* '''Sep-13 Fr'''<br />
<br />
2024 Week 38<br />
<br />
* '''Sep-16 Mo'''<br />
----<br />
* '''Sep-17 Tu''' <br />
----<br />
* '''Sep-18 We''' <br />
----<br />
* '''Sep-19 Th''' <br />
----<br />
* '''Sep-20 Fr'''<br />
<br />
2024 Week 39<br />
<br />
* '''Sep-22 Su'''<br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
* '''Sep-23 Mo'''<br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-24 Tu''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-25 We''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-26 Th''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-27 Fr'''<br />
<br />
<br />
2024 Week 40<br />
<br />
* '''Sep-30 Mo'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-01 Tu''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-02 We''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-03 Th''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-04 Fr'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
<br />
2024 Week 41<br />
<br />
* '''Okt-07 Mo'''<br />
----<br />
* '''Okt-08 Tu''' <br />
----<br />
* '''Okt-09 We''' <br />
----<br />
* '''Okt-10 Th''' <br />
----<br />
* '''Okt-11 Fr'''<br />
<br />
2024 Week 42<br />
<br />
* '''Okt-14 Mo'''<br />
----<br />
* '''Okt-15 Tu''' <br />
----<br />
* '''Okt-16 We''' <br />
----<br />
* '''Okt-17 Th''' <br />
----<br />
* '''Okt-18 Fr'''<br />
<br />
2024 Week 43<br />
<br />
* '''Okt-21 Mo'''<br />
----<br />
* '''Okt-22 Tu''' <br />
----<br />
* '''Okt-23 We''' <br />
----<br />
* '''Okt-24 Th''' <br />
----<br />
* '''Okt-25 Fr'''<br />
::::: <big> '''[[14th Mitochondrial Disease Conference 2024 Padova IT]]'''</big> 2024 Oct 25-27<br />
<br />
2024 Week 44<br />
<br />
* '''Okt-28 Mo'''<br />
----<br />
* '''Okt-29 Tu''' <br />
----<br />
* '''Okt-30 We''' <br />
----<br />
* '''Okt-31 Th''' <br />
----<br />
* '''Nov-01 Fr''' <br />
<br />
2024 Week 45<br />
<br />
* '''Nov-04 Mo'''<br />
----<br />
* '''Nov-05 Tu''' <br />
----<br />
* '''Nov-06 We''' <br />
----<br />
* '''Nov-07 Th''' <br />
----<br />
* '''Nov-08 Fr'''<br />
<br />
2024 Week 46<br />
<br />
* '''Nov-11 Mo'''<br />
----<br />
* '''Nov-12 Tu''' <br />
----<br />
* '''Nov-13 We''' <br />
----<br />
* '''Nov-14 Th''' <br />
----<br />
* '''Nov-15 Fr'''<br />
<br />
<br />
2024 Week 47<br />
<br />
* '''Nov-18 Mo'''<br />
----<br />
* '''Nov-19 Tu''' <br />
----<br />
* '''Nov-20 We''' <br />
----<br />
* '''Nov-21 Th''' <br />
----<br />
* '''Nov-22 Fr'''<br />
<br />
2024 Week 48<br />
<br />
* '''Nov-25 Mo'''<br />
----<br />
* '''Nov-26 Tu''' <br />
----<br />
* '''Nov-27 We''' <br />
----<br />
* '''Nov-28 Th''' <br />
----<br />
* '''Nov-29 Fr'''<br />
<br />
2024 Week 49<br />
<br />
* '''Dez-02 Mo'''<br />
----<br />
* '''Dez-03 Tu''' <br />
----<br />
* '''Dez-04 We''' <br />
----<br />
* '''Dez-05 Th''' <br />
----<br />
* '''Dez-06 Fr'''<br />
<br />
2024 Week 50<br />
<br />
* '''Dez-09 Mo'''<br />
----<br />
* '''Dez-10 Tu''' <br />
----<br />
* '''Dez-11 We''' <br />
----<br />
* '''Dez-12 Th''' <br />
----<br />
* '''Dez-13 Fr'''<br />
<br />
2024 Week 51<br />
<br />
* '''Dez-16 Mo'''<br />
----<br />
* '''Dez-17 Tu''' <br />
----<br />
* '''Dez-18 We''' <br />
----<br />
* '''Dez-19 Th''' <br />
----<br />
* '''Dez-20 Fr'''<br />
<br />
2024 Week 52<br />
<br />
* '''Dez-23 Mo'''<br />
----<br />
* '''Dez-24 Tu''' <br />
----<br />
* '''Dez-25 We''' <br />
----<br />
* '''Dez-26 Th''' <br />
----<br />
* '''Dez-27 Fr'''</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=File:MOSBRI_Consensus_meeting_program.pdf&diff=246480
File:MOSBRI Consensus meeting program.pdf
2024-03-13T11:18:03Z
<p>Tindle Lisa: </p>
<hr />
<div></div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=MOSBRI_Consensus_Meeting_2024_Rome_IT&diff=246479
MOSBRI Consensus Meeting 2024 Rome IT
2024-03-13T11:09:45Z
<p>Tindle Lisa: </p>
<hr />
<div>{{MitoGlobal header page name}}<br />
<br />
{{Publication<br />
|title='''Rome IT''', 2024 Apr 09. MOSBRI Consensus Meeting<br />
|info= [https://www.mosbri.eu/events/meetings/cm-april2024/ Conference website]<br />
|authors= MOSBRI<br />
|year=2024-04-09<br />
|journal=MitoGlobal<br />
|abstract= tba<br />
}}<br />
<br />
== Venue ==<br />
:::: Sapienza University of Rome: Piazzale Aldo Moro, 5, 00185 Roma RM, Italy<br />
<br />
== Program ==<br />
:::: tba<br />
<br />
== Oroboros at MOSBRI Consensus Meeting ==<br />
:::: [[Gnaiger Erich|Erich Gnaiger]]: Quality-controlled high-resolution respirometry: bacterial and clinical applications<br />
<br />
<br />
{{Labeling<br />
|additional=2024, MitoGlobal, ORO, Next<br />
}}<br />
<br />
<br />
[[Image:MitoGlobal.jpg|right|80px|link=http://www.bioblast.at/index.php/MitoGlobal|MitoGlobal]] <br />
Listed under [[MitoGlobal Events]].</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=EMC2024_Ljubljana_SI&diff=246471
EMC2024 Ljubljana SI
2024-03-12T13:23:05Z
<p>Tindle Lisa: </p>
<hr />
<div>{{MitoGlobal header page name}}<br />
<br />
{{Publication<br />
|title='''Ljubljana SI''', 2024 Sep 22-26. EMC 2024 51st European Muscle Conference<br />
|info= [https://www.emc2024ljubljana.com/ Conference website]<br />
|authors=European Society of Muscle Research (ESMR)<br />
|year=2024-09-22<br />
|journal=MitoGlobal<br />
|abstract= EMC 2024 51st European Muscle Conference, Ljubljana, Slovenia, 2024<br />
}}<br />
<br />
== Venue ==<br />
:::: Great Lecture Hall (Velika predavalnica) of the Faculty of Medicine of the University of Ljubljana<br />
:::: Korytkova 2<br />
:::: 1000 Ljubljana (Slovenia)<br />
<br />
== Program ==<br />
:::: Preliminary program available [https://www.emc2024ljubljana.com/programme/ here]<br />
<br />
:::: Satellite symposium and workshop: "Skeletal muscle research - from cell to human" - [https://www.emc2024ljubljana.com/satellite-symposium-and-workshop-skeletal-muscle-research/ ''more details'']<br />
<br />
<br />
{{Labeling<br />
|instruments=<br />
|additional=2024, MitoGlobal, ORO, Next<br />
}}<br />
<br />
<br />
[[Image:MitoGlobal.jpg|right|80px|link=http://www.bioblast.at/index.php/MitoGlobal|MitoGlobal]] <br />
Listed under [[MitoGlobal Events]].</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Current_week_ecosystem_agenda&diff=246469
Template:Current week ecosystem agenda
2024-03-12T11:38:36Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:Science for Ukraine}}<br />
2024 Week 11<br />
<br />
* '''Mar-11 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
----<br />
* '''Mar-12 Tu''' <br />
----<br />
* '''Mar-13 We''' <br />
:{|<br />
| width="100" align="center" |[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''''Rewarded'' Open Access - compensating authors'''<br><br />
Together with the MiP''society'', BEC is raising funds to reward the first 10 papers accepted for publication in BEC in 2024: 600 EUR to attend EBEC2024 and 2-year MiP''membership''.<br />
-»[https://whydonate.com/en/fundraising/BEC Support open access in science]«<br><br />
- »[https://www.bioenergetics-communications.org/index.php/bec/about/submissions Submit a manuscript]«<br />
|}<br />
----<br />
* '''Mar-14 Th'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|} <br />
----<br />
* '''Mar-15 Fr''' <br />
----<br />
<br />
'''<big>Next Week</big>'''<br />
2024 Week 12<br />
<br />
* '''Mar-18 Mo'''<br />
::::: '''[[EU-METAHEART MC2 Meeting 2024 Antalya TR]]''' Mar 18-21<br />
----<br />
* '''Mar-19 Tu''' <br />
:::: 15:05 '''[[Gnaiger Erich|Erich Gnaiger]] presenting at [[EU-METAHEART MC2 Meeting 2024 Antalya TR]]''' - ''[[Donnelly_2024_EU-METAHEART_MC2_Meeting |Impact of hypoxia on mitochondrial function]]''<br />
<br />
----<br />
* '''Mar-20 We''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' What if ''Alert: Error in titrations!'' appears in your O2 analysis template file? '''<br><br />
The O2 analysis template recognizes discrepancies between the protocol selected in the first tab and the imported marks. Check the titration sequence and mark names against the protocol copied from the DLD file.<br><br />
- »'''[[MiPNet24.06 Oxygen flux analysis - DatLab 7.4|O<sub>2</sub> flux analysis]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Mar-21 Th''' <br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you handle well your Hamilton syringes? What is a cleaning cycle?'''<br><br />
"A syringe cleaning cycle consists of filling an empty syringe with a washing solution while immersing [...] also the base of the barrel into the washing solution, without fully removing the plunger, and emptying the syringe into the waste beaker". <br><br />
- »'''[[MiPNet19.14 SOP Hamilton microsyringes]]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
----<br />
* '''Mar-22 Fr'''<br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template_talk:Next_oroboros_ecosystem_agenda&diff=246467
Template talk:Next oroboros ecosystem agenda
2024-03-12T11:20:02Z
<p>Tindle Lisa: /* Next */</p>
<hr />
<div>__TOC__<br />
<br />
::::[[User:Antunes Diana|Antunes Diana]] ([[User talk:Antunes Diana|talk]]) 08:58, 5 May 2020 (CEST) Format for new Agenda/Alerts entries:<br />
<pre style="display: inline-block;"><br />
{|<br />
| logos<br />
| title in bold <br><br />
- link<br />
|}<br />
</pre><br />
<br />
''e.g.,''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Red-loss of data.png|25px|Warning: loss of data]]<br />
|'''Did you know that the proper use of TIP2k-Filter Papers may avoid an unstable O2 slope neg. signal during Instrumental background correction?''' <br><br />
- »[[Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._signal_in_O2_instrumental_BG|Instrumental background]]« and »[[TIP2k Filter Papers]]«<br />
|}<br />
:::: ''See the scheme'':<br />
<br><br />
[[Image:TEMPLATE ALERT.png|none|900px|Agenda/Alerts body text format]]<br />
<br />
<br />
== MitoPedia alert ==<br />
::: Example:<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Measuring fatty acid oxidation (FAO)-linked respiration requires a low concentration of malate '''<br><br />
In the absence of malate, accumulation of Acetyl-CoA inhibits FAO. <br><br />
- »'''[[Fatty acid oxidation pathway control state]]'''«, »'''[https://www.bioblast.at/index.php/Gnaiger_2020_BEC_MitoPathways Mitochondrial Pathways: Chapter 5]'''« <br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Cardoso Luiza]]« <br />
|}<br />
<br />
<br />
=== Next ===<br />
<br />
March 11th<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
<br />
March 25th<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Living cells or intact cells? '''<br><br />
Living cells are frequently labelled as ''intact cells'' in the sense of the total cell count, but ''intact'' may suggest dual meanings of viable or unaffected by a disease or mitochondrial injury. <br><br />
- »'''[[Living cells]]'''«, »'''[[BEC 2020.1]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''« <br><br />
- communicated by »[[Leo Elettra]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
<br />
April 8th<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Is fatty acid oxidation (FAO) considered as CI- or CII-driven respiration? '''<br><br />
Neither. FAO generates acetyl-coA, which will enter the TCA cycle, and FADH<sub>2</sub>, resulting in simultaneous electron transfer into the Q-junction through the electron transferring flavoprotein complex (CETF) and Complex I. <br><br />
- »'''[[Fatty acid oxidation]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''«, »'''[[Gnaiger 2023 MitoFit CII]]'''« <br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Willis Jaime R]]« <br />
|}<br />
<br />
=== Under construction ===<br />
<br />
on hold until the page is updated<br />
:{|<br />
| width="100" align="center" |[[File:FAT4BRAIN logo.png|right|80px|link=https://wiki.oroboros.at/index.php/FAT4BRAIN|FAT4BRAIN]]<br />
|'''A FAO-mito-CNS platform to help fatty acid-related respiration measurements was developed in the FAT4BRAIN project''' <br><br />
- » [[FAT4BRAIN_FAO-mito-CNS_platform|FAT4BRAIN FAO-mito-CNS platform]] «<br />
|}<br />
<br />
== O2k-Brief alert ==<br />
:::* Example:<br />
:{|<br />
| width="100" align="center" | [[File:O2k-brief.png|45px|link=http://wiki.oroboros.at/index.php/O2k-brief|O2k-brief repository]]<br />
|'''Antitumoral properties of triterpenic acid functionalized gold nanoparticles arise from decreasing mitochondrial respiration''' <br><br />
* Mioc M, Mioc A, Racoviceanu R, Ghiulai R, Prodea A, Milan A, Barbu Tudoran L, Oprean C, Ivan V, Șoica C (2023) The antimelanoma biological assessment of triterpenic acid functionalized gold nanoparticles. [[Mioc 2023 Molecules|»Bioblast link«]]<br />
|}<br />
=== Next ===<br />
<br />
== O2k-Publications alert ==<br />
<br />
:::* Example: <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Mitochondria–nucleus communication and its integration within the maintenance of cellular homeostasis constitute key determinants of cellular fate and organism health in the context of cellular stress, homeostasis perturbation, and disease"''' <br><br />
* Temelie M, Talpur R, Dominguez-Prieto M, Dantas Silva A, Cenusa C, Craciun L, Savu DI, Moisoi N (2023) Impaired integrated stress response and mitochondrial integrity modulate genotoxic stress impact and lower the threshold for immune signalling. [[Temelie 2023 Int J Mol Sci|»Bioblast link«]]<br />
:from the O2k-Network »[[UK Leicester Moisoi N]]«<br />
|}<br />
<br />
===='''Author names of O2k-Publications/ Brief for the Agenda vs Bioblast''' ==== <br />
<br />
__NOTOC__ [[File:Expand.png|right|25px|Click to expand or collaps]]<br />
<div class="toccolours mw-collapsible mw-collapsed"><br />
'''Guidelines to update a reference'''<br />
<div class="mw-collapsible-content"><br />
::When creating an O2k-Publication/Brief alert, it is the responsibility of the author to check if the reference is accordingly to the correct guidelines:<br />
[[File:Reference example.png|900px]]<br />
::Correct format for a person called “First Name Surname”: <br />
::In the gray box should be “Surname FN” - '''From where references to be used as O2k-Publication/Brief alerts are copied from.'''<br />
[[File:Gray box reference.png|900px]]<br />
::In the links should be “ Surname First N”<br />
[[File:Authors names links reference.png|900px]]<br />
::'''How to edit:'''<br />
:::A) Check if all authors with profiles in Bioblast (blue links) have their profiles with full name. If they have, proceed to next step (B). If not, you need to move it following the steps “How to move a profile” below.<br />
:::B) Click in “Edit with form”.<br />
:::C) The gray box is edited in “Reference” and the links are changed in “Author(s)”. Change it accordingly and click in “save page” at the end of the page.<br />
[[File:Editing reference.png|900px]]<br />
<br />
'''How to move a profile (instructions sent by Marija):'''<br />
<br />
So let’s take for example my page: <br />
[[Beno M]] <br />
[https://wiki.oroboros.at/index.php?title=Beno_Marija&redirect=no]<br />
<br />
::As you can see there is a redirect from Beno Marija to Beno M. What has to be done is to switch the content of those pages. Here are the steps: <br />
:::1. Go to e.g. “Beno M” on edit<br />
:::2. Click on “Move”<br />
:::3. Change the new title to the full name of the person. In my case it will be Beno M to Beno Marija <br />
[[File:BenoMreference.jpg|500px]]<br />
:::4. Now it should look like that: <br />
[[File:BenoMarijaReference.png|500px]]<br />
:::5. Click on “Move” and leave all the ticked boxes<br />
:::6.Done<br />
::After that you can continue in step B.<br />
::If you have any doubt you can contact Cristiane, Marija or Mario.<br />
</div><br />
</div><br />
<br />
=== Next ===<br />
<br />
:{|<br />
| width="100" align="center" |[[File:BEC2023.3.jpg|right|150px|link=https://doi.org/10.26124/bec:2023-0004| Oliveira 2023 BEC]]<br />
|'''A BEC Spotlight on Rodríguez et al's ''Drosophila'' mitochondrial research methodology''' <br><br />
* Oliveira MF, Aveiro Y, Couto-Lima CA (2023) A navigation chart to avoid turbulence in Drosophila mitochondrial research. Bioenerg Commun 2023.4. https://doi.org/10.26124/bec:2023-0004<br />
:from the O2k-Network »[[BR Rio de Janeiro Oliveira MF]]«<br />
|}<br />
<br />
March 14th<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|}<br />
<br />
== MiPNet ==<br />
:::* Example: <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' "No bubbles should be trapped in the electrolyte reservoir after membrane application and mounting"'''<br><br />
<br />
- »'''[[MiPNet28.10 SmartPOS-service]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[]]«<br />
|}<br />
<br />
=== Next ===<br />
<br />
== O2k-Open Support alert ==<br />
:::*Examples:<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Yellow-take care.png|25px|Info: take care]]<br />
|'''Does your polarographic oxygen sensor (POS) need a deep clean?'''<br><br />
A POS with a very dark anode might need several rounds of ammonia cleaning, possibly including prolonged exposure overnight to restore performance specifications. <br />
<br><br />
- »'''[[MiPNet19.18B POS-service|POS service]]'''«<br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Leo Elettra]]«<br />
|}<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Red-loss of data.png|25px|Warning: loss of data]] <br />
|'''Did you know that a humid environment and/or liquid spillage may lead to a high raw POS signal [V]?'''<br><br />
See how to clean and dry the electrical connections of the OroboPOS-Connector.<br><br />
- »'''[[OroboPOS-Connector#Cleaning_the_electrical_connections|Cleaning the electrical connections]]'''«<br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Unusual stirrer bar rotation? '''<br><br />
A “jumping” stirrer or a slow rotation of the stirrer bar may indicate a problem either with the stirrer itself or with the cleaning of the glass chamber. <br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/Stirrer-Bar%5Cwhite_PVDF%5C15x6_mm#Technical_support Stirrer bar - technical support]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
<br />
=== Next ===<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' How to store the POS overnight and up to several months? '''<br><br />
Fill the chamber and the receptacle of the loosely inserted stopper with 70 % EtOH, add the Cover-slip and switch off the O2K.<br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/MiPNet19.03_O2k-cleaning_and_ISS O2k-cleaning and ISS]'''«<br><br />
- communicated by »[[Leo Elettra]]« and »[[Grings Mateus]]«<br />
|}<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test? '''<br><br />
Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.<br />
<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
<br />
March 18<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' What if ''Alert: Error in titrations!'' appears in your O2 analysis template file? '''<br><br />
The O2 analysis template recognizes discrepancies between the protocol selected in the first tab and the imported marks. Check the titration sequence and mark names against the protocol copied from the DLD file.<br><br />
- »'''[[MiPNet24.06 Oxygen flux analysis - DatLab 7.4|O<sub>2</sub> flux analysis]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
<br />
== O2k-Feedback alert ==<br />
:::* Example (if the person has a profile, link the name to the profile with [[Cecatto C| Cristiane Cecatto]]:<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“Thank you very much for your thorough help. I appreciate the time you took to provide me with all the answers and supportive literature to realize the potential of the O2k-respirometer in bioenergetics research”'''''<br><br />
Badr Ibrahim, PhD from Betterhumans Inc., US<br />
<br><br />
- »'''[[O2k-Feedback]]'''«<br><br />
|}<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“Thank you very much for your thorough help. I appreciate the time you took to provide me with all the answers and supportive literature to realize the potential of the O2k-respirometer in bioenergetics research”'''''<br><br />
Badr Ibrahim, PhD from the O2k-Network »[[UK Leicester Moisoi N]]«<br><br />
- »'''[[O2k-Feedback]]'''«<br><br />
|}<br />
<br />
=== Next ===<br />
<br />
== MitoFit Preprints ==<br />
:::* Example:<br />
:{|<br />
| width="100" align="center"|[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''From preprint to BEC manuscript with published Open Peer Reviews:'''<br><br />
*Komlódi T, Sobotka O, Gnaiger E (2021) Facts and artefacts on the oxygen dependence of hydrogen peroxide production using Amplex UltraRed. Bioenerg Commun 2021.4. [[doi:10.26124/BEC:2021-0004]]<br />
:from the O2k-Network »[[AT Innsbruck Oroboros]]« <br />
|}<br />
<br />
=== Next ===<br />
<br />
== Under discussion ==<br />
<br />
This one needs an update of the Bioblast page and clarification of MiPNet06.03<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Did you enter the correct oxygen solubility factor in DatLab?'''<br><br />
The oxygen solubility factor of the incubation medium, F<sub>M</sub>, expresses the effect of the salt concentration on oxygen solubility relative to pure water. The correct oxygen solubility factor of your experimental medium or buffer needs to be entered in DatLab for proper calculation of the oxygen concentration.<br />
<br><br />
- »'''[[Oxygen solubility factor|Oxygen solubility factor]]'''«<br><br />
- communicated by »[[Schmitt Sabine]]« and »[[ ]]«<br />
<br />
|}<br />
<br />
This one needs a BioBlast link:<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' When filling in the volume of uncoupler in the DatLab mark or the excel template, should one enter the total volume added or the volume to get to the highest flux?'''<br><br />
The volume added until the mark, equal to the highest flux, should be entered. Anything titrated after this mark should be summed to the other volumes before the next mark because this will be considered to calculate the sample dilution. <br />
<br><br />
- »'''[[LINK|LINK]]''' and '''[[MiPNet24.06_Oxygen_flux_analysis_-_DatLab_7.4|O<sub>2</sub> flux analysis with DatLab 7.4]]'''«<br><br />
- communicated by »[[Cardoso Luiza]]« and »[[ ]]«<br />
|}<br />
<br />
<br />
== Removed for correction ==<br />
* '''Nov-30 Mo''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Noisy oxygen signal? Check the OroboPOS and OroboPOS-Connector to clean electrical connections.'''<br><br />
Contaminating grease, salt crystals and moisture can be removed with a dry paper cloth or a paper cloth moistened with water and then absolute ethanol. <br><br />
- »[[OroboPOS-Connector#Cleaning_the_electrical_connections |Cleaning the electrical connections]]« <br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Komlodi Timea]]«<br />
|}<br />
WGT recommended not to use water for cleaning. Erich introduced water for cleaning to remove salt crystals.<br />
<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Red-loss of data.png|25px|Warning: loss of data]]<br />
|'''Do you perform the ''leaky chamber test'' after chamber assembly? '''<br><br />
An unnoticed leak from the chamber may affect your data, therefore we recommend performing the ''Leaky chamber test'' - especially after chamber reassembly. <br><br />
- »[[Talk:O2k-Chamber_MitoPedia#Leaky_Chamber|Leaky chamber test]]« and » https://intern.oroboros.at/index.php/Overnight_test_after_O2k-chamber_assembly«<br />
|}</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template_talk:Next_oroboros_ecosystem_agenda&diff=246466
Template talk:Next oroboros ecosystem agenda
2024-03-12T11:19:22Z
<p>Tindle Lisa: /* Next */</p>
<hr />
<div>__TOC__<br />
<br />
::::[[User:Antunes Diana|Antunes Diana]] ([[User talk:Antunes Diana|talk]]) 08:58, 5 May 2020 (CEST) Format for new Agenda/Alerts entries:<br />
<pre style="display: inline-block;"><br />
{|<br />
| logos<br />
| title in bold <br><br />
- link<br />
|}<br />
</pre><br />
<br />
''e.g.,''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Red-loss of data.png|25px|Warning: loss of data]]<br />
|'''Did you know that the proper use of TIP2k-Filter Papers may avoid an unstable O2 slope neg. signal during Instrumental background correction?''' <br><br />
- »[[Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._signal_in_O2_instrumental_BG|Instrumental background]]« and »[[TIP2k Filter Papers]]«<br />
|}<br />
:::: ''See the scheme'':<br />
<br><br />
[[Image:TEMPLATE ALERT.png|none|900px|Agenda/Alerts body text format]]<br />
<br />
<br />
== MitoPedia alert ==<br />
::: Example:<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Measuring fatty acid oxidation (FAO)-linked respiration requires a low concentration of malate '''<br><br />
In the absence of malate, accumulation of Acetyl-CoA inhibits FAO. <br><br />
- »'''[[Fatty acid oxidation pathway control state]]'''«, »'''[https://www.bioblast.at/index.php/Gnaiger_2020_BEC_MitoPathways Mitochondrial Pathways: Chapter 5]'''« <br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Cardoso Luiza]]« <br />
|}<br />
<br />
<br />
=== Next ===<br />
<br />
March 11th<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
<br />
March 25th<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Living cells or intact cells? '''<br><br />
Living cells are frequently labelled as ''intact cells'' in the sense of the total cell count, but ''intact'' may suggest dual meanings of viable or unaffected by a disease or mitochondrial injury. <br><br />
- »'''[[Living cells]]'''«, »'''[[BEC 2020.1]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''« <br><br />
- communicated by »[[Leo Elettra]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
<br />
April 8th<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Is fatty acid oxidation (FAO) considered as CI- or CII-driven respiration? '''<br><br />
Neither. FAO generates acetyl-coA, which will enter the TCA cycle, and FADH<sub>2</sub>; resulting in simultaneous electron transfer into the Q-junction through the electron transferring flavoprotein complex (CETF) and Complex I. <br><br />
- »'''[[Fatty acid oxidation]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''«, »'''[[Gnaiger 2023 MitoFit CII]]'''« <br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Willis Jaime R]]« <br />
|}<br />
<br />
=== Under construction ===<br />
<br />
on hold until the page is updated<br />
:{|<br />
| width="100" align="center" |[[File:FAT4BRAIN logo.png|right|80px|link=https://wiki.oroboros.at/index.php/FAT4BRAIN|FAT4BRAIN]]<br />
|'''A FAO-mito-CNS platform to help fatty acid-related respiration measurements was developed in the FAT4BRAIN project''' <br><br />
- » [[FAT4BRAIN_FAO-mito-CNS_platform|FAT4BRAIN FAO-mito-CNS platform]] «<br />
|}<br />
<br />
== O2k-Brief alert ==<br />
:::* Example:<br />
:{|<br />
| width="100" align="center" | [[File:O2k-brief.png|45px|link=http://wiki.oroboros.at/index.php/O2k-brief|O2k-brief repository]]<br />
|'''Antitumoral properties of triterpenic acid functionalized gold nanoparticles arise from decreasing mitochondrial respiration''' <br><br />
* Mioc M, Mioc A, Racoviceanu R, Ghiulai R, Prodea A, Milan A, Barbu Tudoran L, Oprean C, Ivan V, Șoica C (2023) The antimelanoma biological assessment of triterpenic acid functionalized gold nanoparticles. [[Mioc 2023 Molecules|»Bioblast link«]]<br />
|}<br />
=== Next ===<br />
<br />
== O2k-Publications alert ==<br />
<br />
:::* Example: <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Mitochondria–nucleus communication and its integration within the maintenance of cellular homeostasis constitute key determinants of cellular fate and organism health in the context of cellular stress, homeostasis perturbation, and disease"''' <br><br />
* Temelie M, Talpur R, Dominguez-Prieto M, Dantas Silva A, Cenusa C, Craciun L, Savu DI, Moisoi N (2023) Impaired integrated stress response and mitochondrial integrity modulate genotoxic stress impact and lower the threshold for immune signalling. [[Temelie 2023 Int J Mol Sci|»Bioblast link«]]<br />
:from the O2k-Network »[[UK Leicester Moisoi N]]«<br />
|}<br />
<br />
===='''Author names of O2k-Publications/ Brief for the Agenda vs Bioblast''' ==== <br />
<br />
__NOTOC__ [[File:Expand.png|right|25px|Click to expand or collaps]]<br />
<div class="toccolours mw-collapsible mw-collapsed"><br />
'''Guidelines to update a reference'''<br />
<div class="mw-collapsible-content"><br />
::When creating an O2k-Publication/Brief alert, it is the responsibility of the author to check if the reference is accordingly to the correct guidelines:<br />
[[File:Reference example.png|900px]]<br />
::Correct format for a person called “First Name Surname”: <br />
::In the gray box should be “Surname FN” - '''From where references to be used as O2k-Publication/Brief alerts are copied from.'''<br />
[[File:Gray box reference.png|900px]]<br />
::In the links should be “ Surname First N”<br />
[[File:Authors names links reference.png|900px]]<br />
::'''How to edit:'''<br />
:::A) Check if all authors with profiles in Bioblast (blue links) have their profiles with full name. If they have, proceed to next step (B). If not, you need to move it following the steps “How to move a profile” below.<br />
:::B) Click in “Edit with form”.<br />
:::C) The gray box is edited in “Reference” and the links are changed in “Author(s)”. Change it accordingly and click in “save page” at the end of the page.<br />
[[File:Editing reference.png|900px]]<br />
<br />
'''How to move a profile (instructions sent by Marija):'''<br />
<br />
So let’s take for example my page: <br />
[[Beno M]] <br />
[https://wiki.oroboros.at/index.php?title=Beno_Marija&redirect=no]<br />
<br />
::As you can see there is a redirect from Beno Marija to Beno M. What has to be done is to switch the content of those pages. Here are the steps: <br />
:::1. Go to e.g. “Beno M” on edit<br />
:::2. Click on “Move”<br />
:::3. Change the new title to the full name of the person. In my case it will be Beno M to Beno Marija <br />
[[File:BenoMreference.jpg|500px]]<br />
:::4. Now it should look like that: <br />
[[File:BenoMarijaReference.png|500px]]<br />
:::5. Click on “Move” and leave all the ticked boxes<br />
:::6.Done<br />
::After that you can continue in step B.<br />
::If you have any doubt you can contact Cristiane, Marija or Mario.<br />
</div><br />
</div><br />
<br />
=== Next ===<br />
<br />
:{|<br />
| width="100" align="center" |[[File:BEC2023.3.jpg|right|150px|link=https://doi.org/10.26124/bec:2023-0004| Oliveira 2023 BEC]]<br />
|'''A BEC Spotlight on Rodríguez et al's ''Drosophila'' mitochondrial research methodology''' <br><br />
* Oliveira MF, Aveiro Y, Couto-Lima CA (2023) A navigation chart to avoid turbulence in Drosophila mitochondrial research. Bioenerg Commun 2023.4. https://doi.org/10.26124/bec:2023-0004<br />
:from the O2k-Network »[[BR Rio de Janeiro Oliveira MF]]«<br />
|}<br />
<br />
March 14th<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|}<br />
<br />
== MiPNet ==<br />
:::* Example: <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' "No bubbles should be trapped in the electrolyte reservoir after membrane application and mounting"'''<br><br />
<br />
- »'''[[MiPNet28.10 SmartPOS-service]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[]]«<br />
|}<br />
<br />
=== Next ===<br />
<br />
== O2k-Open Support alert ==<br />
:::*Examples:<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Yellow-take care.png|25px|Info: take care]]<br />
|'''Does your polarographic oxygen sensor (POS) need a deep clean?'''<br><br />
A POS with a very dark anode might need several rounds of ammonia cleaning, possibly including prolonged exposure overnight to restore performance specifications. <br />
<br><br />
- »'''[[MiPNet19.18B POS-service|POS service]]'''«<br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Leo Elettra]]«<br />
|}<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Red-loss of data.png|25px|Warning: loss of data]] <br />
|'''Did you know that a humid environment and/or liquid spillage may lead to a high raw POS signal [V]?'''<br><br />
See how to clean and dry the electrical connections of the OroboPOS-Connector.<br><br />
- »'''[[OroboPOS-Connector#Cleaning_the_electrical_connections|Cleaning the electrical connections]]'''«<br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Unusual stirrer bar rotation? '''<br><br />
A “jumping” stirrer or a slow rotation of the stirrer bar may indicate a problem either with the stirrer itself or with the cleaning of the glass chamber. <br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/Stirrer-Bar%5Cwhite_PVDF%5C15x6_mm#Technical_support Stirrer bar - technical support]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
<br />
=== Next ===<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' How to store the POS overnight and up to several months? '''<br><br />
Fill the chamber and the receptacle of the loosely inserted stopper with 70 % EtOH, add the Cover-slip and switch off the O2K.<br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/MiPNet19.03_O2k-cleaning_and_ISS O2k-cleaning and ISS]'''«<br><br />
- communicated by »[[Leo Elettra]]« and »[[Grings Mateus]]«<br />
|}<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test? '''<br><br />
Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.<br />
<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
<br />
March 18<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' What if ''Alert: Error in titrations!'' appears in your O2 analysis template file? '''<br><br />
The O2 analysis template recognizes discrepancies between the protocol selected in the first tab and the imported marks. Check the titration sequence and mark names against the protocol copied from the DLD file.<br><br />
- »'''[[MiPNet24.06 Oxygen flux analysis - DatLab 7.4|O<sub>2</sub> flux analysis]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
<br />
== O2k-Feedback alert ==<br />
:::* Example (if the person has a profile, link the name to the profile with [[Cecatto C| Cristiane Cecatto]]:<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“Thank you very much for your thorough help. I appreciate the time you took to provide me with all the answers and supportive literature to realize the potential of the O2k-respirometer in bioenergetics research”'''''<br><br />
Badr Ibrahim, PhD from Betterhumans Inc., US<br />
<br><br />
- »'''[[O2k-Feedback]]'''«<br><br />
|}<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“Thank you very much for your thorough help. I appreciate the time you took to provide me with all the answers and supportive literature to realize the potential of the O2k-respirometer in bioenergetics research”'''''<br><br />
Badr Ibrahim, PhD from the O2k-Network »[[UK Leicester Moisoi N]]«<br><br />
- »'''[[O2k-Feedback]]'''«<br><br />
|}<br />
<br />
=== Next ===<br />
<br />
== MitoFit Preprints ==<br />
:::* Example:<br />
:{|<br />
| width="100" align="center"|[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''From preprint to BEC manuscript with published Open Peer Reviews:'''<br><br />
*Komlódi T, Sobotka O, Gnaiger E (2021) Facts and artefacts on the oxygen dependence of hydrogen peroxide production using Amplex UltraRed. Bioenerg Commun 2021.4. [[doi:10.26124/BEC:2021-0004]]<br />
:from the O2k-Network »[[AT Innsbruck Oroboros]]« <br />
|}<br />
<br />
=== Next ===<br />
<br />
== Under discussion ==<br />
<br />
This one needs an update of the Bioblast page and clarification of MiPNet06.03<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Did you enter the correct oxygen solubility factor in DatLab?'''<br><br />
The oxygen solubility factor of the incubation medium, F<sub>M</sub>, expresses the effect of the salt concentration on oxygen solubility relative to pure water. The correct oxygen solubility factor of your experimental medium or buffer needs to be entered in DatLab for proper calculation of the oxygen concentration.<br />
<br><br />
- »'''[[Oxygen solubility factor|Oxygen solubility factor]]'''«<br><br />
- communicated by »[[Schmitt Sabine]]« and »[[ ]]«<br />
<br />
|}<br />
<br />
This one needs a BioBlast link:<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' When filling in the volume of uncoupler in the DatLab mark or the excel template, should one enter the total volume added or the volume to get to the highest flux?'''<br><br />
The volume added until the mark, equal to the highest flux, should be entered. Anything titrated after this mark should be summed to the other volumes before the next mark because this will be considered to calculate the sample dilution. <br />
<br><br />
- »'''[[LINK|LINK]]''' and '''[[MiPNet24.06_Oxygen_flux_analysis_-_DatLab_7.4|O<sub>2</sub> flux analysis with DatLab 7.4]]'''«<br><br />
- communicated by »[[Cardoso Luiza]]« and »[[ ]]«<br />
|}<br />
<br />
<br />
== Removed for correction ==<br />
* '''Nov-30 Mo''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Noisy oxygen signal? Check the OroboPOS and OroboPOS-Connector to clean electrical connections.'''<br><br />
Contaminating grease, salt crystals and moisture can be removed with a dry paper cloth or a paper cloth moistened with water and then absolute ethanol. <br><br />
- »[[OroboPOS-Connector#Cleaning_the_electrical_connections |Cleaning the electrical connections]]« <br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Komlodi Timea]]«<br />
|}<br />
WGT recommended not to use water for cleaning. Erich introduced water for cleaning to remove salt crystals.<br />
<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Red-loss of data.png|25px|Warning: loss of data]]<br />
|'''Do you perform the ''leaky chamber test'' after chamber assembly? '''<br><br />
An unnoticed leak from the chamber may affect your data, therefore we recommend performing the ''Leaky chamber test'' - especially after chamber reassembly. <br><br />
- »[[Talk:O2k-Chamber_MitoPedia#Leaky_Chamber|Leaky chamber test]]« and » https://intern.oroboros.at/index.php/Overnight_test_after_O2k-chamber_assembly«<br />
|}</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=EU-METAHEART_Kick-off_meeting_Brussels_BE&diff=246455
EU-METAHEART Kick-off meeting Brussels BE
2024-03-12T08:58:27Z
<p>Tindle Lisa: </p>
<hr />
<div>{{MitoGlobal header page name}}<br />
{{Publication<br />
|title=[[File:COST Logo.jpg|left|120px|COST Action]][[File:EU-METAHEART logo.jpg|right|70px|EU-METAHEART]]'''Brussels BE''', 2023 October 18. EU-METAHEART Kick-off meeting - first MC meeting for COST Action project.<br />
|info=[[EU-METAHEART]]<br />
|authors=EU-METAHEART<br />
|year=2023-10-18<br />
|journal=MitoGlobal<br />
|abstract='''COST CA22169 METAHEART Kick-off meeting MC1, Brussels, Belguim, 2023-10-18'''<br />
}}<br />
<br />
__TOC__<br />
== General information ==<br />
:::: The first meeting of the EU-METAHEART management committee (MC). The COST Action “EUropean network to tackle METAbolic alterations in HEART failure” (EU-METAHEART) brings together excellent researchers from Europe to contribute a broad spectrum of scientific expertise, cutting-edge technologies, scientific exchange and education to foster breakthrough science that moves the field forward towards improving the treatment of patients with heart failure. <br />
<br />
== Venue ==<br />
:::: '''[https://www.cost.eu/contact/ COST Association]'''<br />
:::: Avenue du Boulevard - Bolwerklaan 21, 23rd floor<br />
:::: 1210 Brussels | Belgium<br />
<br />
== Organizers ==<br />
:::: COST Association - European Cooperation in Science and Technology<br />
:::: Action Contact: [[Maack C|Prof Christoph Maack]], University Clinic Würzburg, DE<br />
:::: COST Staff: Dr Inga Dadeshidze, Ms Jeannette Nchung Oru<br />
:::: [[Gnaiger Erich |Erich Gnaiger]] is part of the Management Committee of CA22169 - EUropean network to tackle METAbolic alterations in HEART failure (EU-METAHEART)<br />
<br />
== Program ==<br />
:::: 09:30 to 17:00 - https://crisiscenter.be/en/newsroom/shooting-brussels<br />
::::* Welcome<br />
::::* Introductions<br />
::::* COST Action management information<br />
::::* Project presentation<br />
::::* Breakout discussions<br />
::::* Election<br />
<br />
<br />
== Oroboros at EU-METAHEART Kick-off meeting ==<br />
:::: [[Gnaiger Erich |Erich Gnaiger]] will be attending as a member of the management committee.<br />
<br />
<br />
== Support ==<br />
:::: [[File:Flag yellow low.jpg|left|100px]] Funded by the European Union.<br />
<br/><br />
<br/><br />
:::: [[Image:COST Logo.jpg|left|140pxE]] COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career, and innovation. - [http://www.cost.eu/ www.cost.eu]<br />
<br />
<br />
[[Image:MitoGlobal.jpg|right|80px|link=http://www.bioblast.at/index.php/MitoGlobal|MitoGlobal]] <br />
Listed under [[MitoGlobal Events]].<br />
<br />
{{Labeling<br />
|additional=MitoGlobal, 2023, ORO, EU-METAHEART events<br />
}}</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Projects&diff=246454
Projects
2024-03-12T08:57:19Z
<p>Tindle Lisa: </p>
<hr />
<div>{{OROBOROS_header_page_name}}<br />
<br />
:::* Oroboros Instruments is involved in an extensive range of research projects across the full scope of our academic expertise.<br />
<br />
<br />
== Ongoing projects ==<br />
<br />
{| class="wikitable"<br />
|- class="hintergrundfarbe6"<br />
! Project<br />
! Start<br />
! End<br />
! Funding agency<br />
! Role<br />
|-<br />
| [[Functional Mitochondrial Diagnostics]] [[File:VASCage logo.png|90px|VASCage|link=https://www.vascage.at/]]<br />
| 2023-04-01<br />
| 2027-03-31<br />
| COMET programme by the Federal Ministries for Climate Protection (BMK) and Economics (BMAW) and the federal states Tyrol, Salzburg and Vienna<br />
<br />
| Project partner<br />
<br />
|-<br />
| [[Oroboros Robotics| Oroboros Robotics]]<br />
| 2023-08-01<br />
| 2025-08-20<br />
| [[File:FFG-logo.png|60px|FFG Austrian Research Promotion Agency]] Austrian Research Promotion Funding Agency (FFG)<br />
<br />
| Company partner<br />
<br />
|-<br />
| [[ALAS]]<br />
| 2022-02-01<br />
| 2025-01-31<br />
| [[File:FFG-logo.png|60px|FFG Austrian Research Promotion Agency]] Austrian Research Promotion Funding Agency (FFG)<br />
| Consortium partner<br />
|-<br />
| [[TissueModels]]<br />
| 2020-04-01<br />
| 2024-03-31<br />
| [[File:FFG-logo.png|60px|FFG Austrian Research Promotion Agency]] Austrian Research Promotion Funding Agency (FFG)<br />
| Consortium partner<br />
|}<br />
== Project affiliations ==<br />
<br />
{| class="wikitable"<br />
|- class="hintergrundfarbe6"<br />
! Project<br />
! Start<br />
! End<br />
! Funding agency<br />
<br />
|-<br />
<br />
| [[EU-METAHEART]] [[Image:EU-METAHEART logo.jpg|70px|link=EU-METAHEART]]<br />
| 2023-10-18 <br />
| 2027-10-17<br />
| [[Image:COST Logo.jpg|150px|CA22169 - EUropean network to tackle METAbolic alterations in HEART failure (EU-METAHEART)]] CA22169 - EUropean network to tackle METAbolic alterations in HEART failure (EU-METAHEART) <br />
|-<br />
<br />
| [[CureMILS]] <br />
| 2021-06-01<br />
| 2024-05-31<br />
| [[File:EJP-RD logo.png|150px|European Joint Programme on Rare Diseases - JTC2020]] European Joint Programme on Rare Diseases - JTC2020<br />
|-<br />
<br />
|}<br />
== Past projects ==<br />
<br />
{| class="wikitable"<br />
|- class="hintergrundfarbe6"<br />
! Project<br />
! Start<br />
! End<br />
! Funding agency<br />
! Role<br />
|-<br />
<br />
| [[MitoKIN|MitoKIN]]<br />
| 2020-02-03<br />
| 2023-01-31 extended to 2024-01-31<br />
| [[File:FFG-logo.png|60px|FFG Austrian Research Promotion Agency]] Austrian Research Promotion Funding Agency (FFG)<br />
<br />
| Consortium partner<br />
|-<br />
| [[FAT4BRAIN]] [[File:FAT4BRAIN logo.png|90px|FAT4BRAIN|link=https://wiki.oroboros.at/index.php/FAT4BRAIN]]<br />
| 2019-11-01<br />
| 2022-10-31 extended to 2023-04-30<br />
| [[File:Horizon2020 logo jpg.jpg|80px|Horizon2020 logo jpg.jpg]] EU Framework Programme Horizon 2020 (WIDESPREAD)<br />
| Consortium partner<br />
|-<br />
| [[MtFOIE_GRAS|mtFOIE GRAS]] [[File:MtFOIEGRAS.png|80px|mt FOIE GRAS|link=http://wiki.oroboros.at/index.php/MtFOIE_GRAS]]<br />
| 2017-06-01<br />
| 2021-05-31 extended to 2022-08-31<br />
| [[File:Marie Curie.jpg|60px|Marie Skłodowska-Curie Action]] Marie Skłodowska-Curie Action (RISE)<br />
<br />
| Consortium partner<br />
|-<br />
| [[SPIN]] [[File:SPIN.png|80px|SPIN|link=http://wiki.oroboros.at/index.php/SPIN]] <br />
| 2018-07-01<br />
| 2022-06-30<br />
| [[File:FWF.png|60px|FWF]] FWF Austrian Science Fund<br />
<br />
| Collaborator<br />
|-<br />
| [[NextGen-O2k|NextGen-O2k H2020 SME Phase 2]] [[File:NextGenO2k logo.jpg|90px|link=https://www.oroboros.at/index.php/nextgen-o2k/]]<br />
| 2019-06-01<br />
| 2021-05-31, extended to 2021-10-31<br />
| [[File:Horizon2020 logo jpg.jpg|80px|Horizon2020 logo jpg.jpg]] EU Framework Programme Horizon 2020<br />
<br />
|-<br />
| [[TRANSMIT|TRANSMIT]] [[File:TRANSMIT Acronym.jpg|80px|TRANSMIT|link=http://wiki.oroboros.at/index.php/TRANSMIT]]<br />
| 2017-01-01<br />
| 2021-06-30<br />
| [[File:Marie Curie.jpg|60px|Marie Skłodowska-Curie Action]] Marie Skłodowska-Curie Action (ITN)<br />
<br />
|-<br />
| [[COST_Action_MitoEAGLE|MitoEAGLE]] [[File:MITOEAGLE-representation.jpg|80px|COST Action MitoEAGLE|link=http://www.mitoglobal.org/index.php/MitoEAGLE]]<br />
| 2016-09-12<br />
| 2021-02-28<br />
| [[File:EU-logo.jpg|70px|e-COST MitoEAGLE countries|link=http://www.cost.eu/COST_Actions/ca/CA15203?parties]] EU Framework Programme Horizon 2020 COST Action [[File:COST Logo.jpg|90px|e-COST MitoEAGLE|link=http://www.cost.eu/COST_Actions/ca/CA15203]] [[File:Horizon2020 logo jpg.jpg|80px|Horizon2020 logo jpg.jpg]]<br />
<br />
|-<br />
<br />
| [[REMIX|REMIX]] [[File:REMIX.png|80px|REMIX|link=http://wiki.oroboros.at/index.php/REMIX]]<br />
| 2016-10-01<br />
| 2021-01-31<br />
| [[File:Marie Curie.jpg|60px|Marie Skłodowska-Curie Action]] Marie Skłodowska-Curie Action (ITN)<br />
<br />
|-<br />
<br />
| [[TRACT|TRACT]] [[File:TRACT logo.png|80px|TRACT|link=http://wiki.oroboros.at/index.php/TRACT]]<br />
| 2016-10-01<br />
| 2020-09-30<br />
| [[File:Marie Curie.jpg|60px|Marie Skłodowska-Curie Action]] Marie Skłodowska-Curie Action (ITN)<br />
<br />
<br />
|-<br />
<br />
| [[Innovationsscheck_PLUS 2|Innovationsscheck PLUS 2]]<br />
| 2018-08-13<br />
| 2019-08-12<br />
| [[File:FFG-logo.png|60px|FFG Austrian Research Promotion Agency]] Austrian Reserach Promotion Funding Agency (FFG)<br />
|-<br />
| [[K-Regio_MitoFit|K-Regio MitoFit]] [[File:Logo MitoFit.jpg|120px|MitoFit|link=http://www.mitofit.org/index.php/MitoFit]]<br />
| 2015-05-01<br />
| 2018-04-30; extended to 2018-10-31<br />
| [[File:Tirol Logo Standortagentur.jpg|80px|Tirol Logo Standortagentur.jpg]] Tyrolean Government - Standortagentur Tirol<br />
|-<br />
| [[Innovationsscheck_PLUS|Innovationsscheck PLUS]]<br />
| 2017-02-23<br />
| 2018-02-22<br />
| [[File:FFG-logo.png|60px|FFG Austrian Research Promotion Agency]] Austrian Reserach Promotion Funding Agency (FFG)<br />
|-<br />
| [[NextGen-O2k H2020 SME Phase 1|NextGen-O2k H2020 SME Phase 1]]<br />
| 2018-02-01<br />
| 2018-05-31<br />
| [[File:Horizon2020 logo jpg.jpg|80px|Horizon2020 logo jpg.jpg]] EU Framework Programme Horizon 2020<br />
|-<br />
| [[FEMtech_Internship_for_students|FEMtech Internship for students]]<br />
| 2017-06-01<br />
| 2017-08-09<br />
| [[File:FFG-logo.png|60px|FFG Austrian Research Promotion Agency]] Austrian Research Promotion Funding Agency (FFG)<br />
|-<br />
| [[O2k-Innovation]]<br />
| 2015-02-01<br />
| 2017-01-31<br />
| [[File:Sponsorlogo gefoerdert RGB.jpg|80px|Sponsorlogo gefoerdert RGB.jpg]] Tyrolean Government - Land Tirol<br />
|-<br />
| [[Oncotyrol|Oncotyrol]] [[File:Logo oncotyrol.jpg|80px|Oncotyrol]]<br />
| 2012-07-01<br />
| 2015-06-30<br />
| [[File:FFG-logo.png|60px|FFG Austrian Research Promotion Agency]] Austrian Research Promotion Funding Agency (FFG)<br />
|-<br />
| [[MitoCom_O2k-Fluorometer|MitoCom O2k-Fluorometer]] [[File:Mitocom-Logo K-Regio.jpg|80px|MitoCom]]<br />
| 2011-05-01<br />
| 2014-07-31<br />
| [[File:K-Regio Icon Englisch 01.jpg|80px|K-Regio Icon Englisch 01.jpg]] Tyrolean Government - Land Tirol, European Regional Development Fund (ERDF) and K-Regio<br />
|}<br />
<br />
== Keywords ==<br />
{{Keywords: Oroboros Laboratories}}</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:O2k-PublicationAlert2024&diff=246422
Template:O2k-PublicationAlert2024
2024-03-11T09:00:23Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:OROBOROS Slogan}}<br />
::::<big>» Listed in '''[[OROBOROS_INSTRUMENTS|Oroboros Ecosystem Agenda ]]'''</big><br />
__TOC__<br />
== Mar 2024 ==<br />
* '''Mar-14 Th'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|} <br />
----<br />
* '''Mar-06 We''' <br />
:{|<br />
| width="100" align="center" |[[File:BEC2024.1.jpg|right|150px|link=https://doi.org/10.26124/bec:2024-0001 |Gross 2024 BEC]]<br />
|'''The tale of two “best-friends,” proteins BID & MTCH2, pivotal regulators of the apoptosis and metabolism programs at the mitochondria.''' <br><br />
* Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001<br />
|}<br />
----<br />
== Feb 2024 ==<br />
* '''Feb-29 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Bed rest results in a decrease in skeletal muscle mitochondrial respiratory capacity, mainly as a result of an observed decrease in mitochondrial content"''' <br><br />
* Noone J, Damiot A, Kenny H, Chery I, Zahariev A, Normand S, Crampes F, de Glisezinski I, Rochfort KD, Laurens C, Bareille MP, Simon C, Bergouignan A, Blanc S, O'Gorman DJ (2023) The impact of 60 days of -6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics. [[Noone 2023 J Physiol|»Bioblast link«]]<br />
:from the O2k-Networks »[[US FL Orlando Goodpaster BH]]« , »[[FR Strasbourg Blanc S]]« , »[[IE Dublin O Gorman D]]«<br />
|}<br />
----<br />
* '''Feb-15 Th''' - International Childhood Cancer Day<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Deleterious mtDNA mutations contribute significantly to the tumorigenesis of pediatric cancers"''' <br><br />
* Triska P, Kaneva K, Merkurjev D, Sohail N, Falk MJ, Triche TJ Jr, Biegel JA, Gai X (2019) Landscape of germline and somatic mitochondrial DNA mutations in pediatric malignancies. [[Triska 2019 Cancer Res|»Bioblast link«]]<br />
:from the O2k-Network »[[US_PA_Philadelphia_Falk_MJ]]«<br />
|}<br />
----<br />
* '''Feb-05 Mo'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"We demonstrated deficient platelet mitochondrial respiratory chain functions, oxidative phosphorylation (OXPHOS), and electron transfer (ET) capacity with complex I (CI)-linked substrates, and reduced [...] endogenous platelet coenzyme Q10 (CoQ10) concentration in UC [urothelial carcinoma] patients."''' <br><br />
* Palacka P, Gvozdjáková A, Rausová Z, Kucharská J, Slopovský J, Obertová J, Furka D, Furka S, Singh KK, Sumbalová Z (2021) Platelet mitochondrial bioenergetics reprogramming in patients with urothelial carcinoma. [[Palacka 2021 Int J Mol Sci|»Bioblast link«]]<br />
:from the O2k-Network »[[SK Bratislava Sumbalova Z]]«<br />
|}<br />
----<br />
== Jan 2024 ==<br />
<br />
* '''Jan-04 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Oxygen Consumption Rate (OCR) measurements of fresh and cryopreserved placental specimens are comparable whereas snap frozen procedure impairs mitochondrial activity"''' <br><br />
* Giovarelli M, Serati A, Zecchini S, Guelfi F, Clementi E, Mandò C (2023) Cryopreserved placental biopsies maintain mitochondrial activity for high-resolution respirometry. [[Giovarelli 2023 Mol Med|»Bioblast link«]]<br />
:from the O2k-Network »[[IT Milan Clementi E]]«<br />
|}<br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:MitoPediaAlert2024&diff=246421
Template:MitoPediaAlert2024
2024-03-11T08:59:47Z
<p>Tindle Lisa: </p>
<hr />
<div>:::::: <big>''A collection from the »[[OROBOROS_INSTRUMENTS|Bioblast Agenda]]«</big><br />
__TOC__<br />
== Mar 2024 ==<br />
* '''Mar-11 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
----<br />
== Feb 2024 ==<br />
* '''Feb-26 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' ATP synthase = phosphorylation system? '''<br><br />
No, the phosphorylation system consists of adenine nucleotide translocase, phosphate carrier, and ATP synthase, which carry out the steps in the phosphorylation pathway. <br><br />
- »'''[[Phosphorylation pathway]]'''«, »'''[https://www.bioblast.at/index.php/Gnaiger_2020_BEC_MitoPathways Mitochondrial Pathways: Chapter 2.2]'''« <br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Feb-12 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' What is the O<sub>2</sub> solubility factor of the medium (''F''<sub>M</sub>) and why is it important? '''<br><br />
''F''<sub>M</sub> expresses the effect of the salt concentration on oxygen solubility relative to pure water, and varies depending on the temperature and composition of the medium. The correct ''F''<sub>M</sub> needs to be entered in DatLab when performing an air calibration. <br><br />
- »'''[[Oxygen solubility factor]]'''« , »'''[[Oxygen_calibration_-_DatLab#Air_calibration_in_DatLab|Air calibration in DatLab]]'''« <br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
== Jan 2024 ==<br />
* '''Jan-31 We''' <br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Can the S-pathway O<sub><small>2</small></sub> flux be derived by subtracting N-pathway O<sub><small>2</small></sub> flux from NS-pathway O<sub><small>2</small></sub> flux?'''<br><br />
No, the sum of the O<sub><small>2</small></sub> fluxes measured in the presence of NADH-linked substrates alone and succinate as the single substrate is typically higher than using a combination of all these substrates. This effect is described as incomplete additivity: <br><br />
- »'''[[Additive effect of convergent electron flow]]'''« <br><br />
- communicated by »[[Cardoso Luiza]]« and »[[Grings Mateus]]« <br />
|}<br />
----<br />
* '''Jan-02 Tu'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' New year, new state? What is REN state? '''<br><br />
REN state is now distinguished from ROX state: REN is measured in mitochondrial preparations without addition of substrates, whereas ROX is due to oxidative side reactions remaining after inhibition of the electron transfer pathway. <br> <br />
- »'''[[Residual endogenous substrates|REN]]'''«, »'''[[Residual oxygen consumption|ROX]]'''« <br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]« <br />
|} <br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Next_oroboros_ecosystem_agenda&diff=246418
Template:Next oroboros ecosystem agenda
2024-03-11T07:43:47Z
<p>Tindle Lisa: </p>
<hr />
<div><br />
2024 Week 13<br />
<br />
* '''Mar-25 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Living cells or intact cells? '''<br><br />
Living cells are frequently labelled as ''intact cells'' in the sense of the total cell count, but ''intact'' may suggest dual meanings of viable or unaffected by a disease or mitochondrial injury. <br><br />
- »'''[[Living cells]]'''«, »'''[[BEC 2020.1]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''« <br><br />
- communicated by »[[Leo Elettra]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Mar-26 Tu''' <br />
----<br />
* '''Mar-27 We''' <br />
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* '''Mar-28 Th''' <br />
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* '''Mar-29 Fr'''<br />
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2024 Week 14<br />
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* '''Apr-01 Mo''' <br />
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* '''Apr-04 Th''' <br />
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* '''Apr-05 Fr'''<br />
<br />
2024 Week 15<br />
<br />
* '''Apr-08 Mo'''<br />
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* '''Apr-09 Tu''' <br />
::::: <big> '''[[MOSBRI Consensus Meeting 2024 Rome IT]]'''</big> <br />
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* '''Apr-10 We''' <br />
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* '''Apr-11 Th''' <br />
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* '''Apr-12 Fr'''<br />
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2024 Week 16<br />
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* '''Apr-15 Mo''' <br />
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* '''Apr-17 We''' <br />
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* '''Apr-18 Th''' <br />
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* '''Apr-19 Fr'''<br />
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2024 Week 17<br />
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* '''Apr-22 Mo'''<br />
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* '''Apr-23 Tu''' <br />
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* '''Apr-25 Th''' <br />
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* '''Apr-26 Fr'''<br />
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2024 Week 18<br />
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* '''Apr-29 Mo'''<br />
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* '''Apr-30 Tu''' <br />
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* '''May-01 We''' <br />
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* '''May-02 Th''' <br />
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* '''May-03 Fr'''<br />
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2024 Week 19<br />
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* '''May-06 Mo'''<br />
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* '''May-07 Tu''' <br />
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* '''May-08 We''' <br />
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* '''May-09 Th''' <br />
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* '''May-10 Fr'''<br />
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2024 Week 20<br />
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* '''May-13 Mo'''<br />
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* '''May-14 Tu''' <br />
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* '''May-15 We''' <br />
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* '''May-16 Th''' <br />
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* '''May-17 Fr'''<br />
<br />
2024 Week 21<br />
<br />
* '''May-20 Mo''' <br />
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* ''May-21 Tu''' <br />
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* '''May-22 We''' <br />
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* '''May-23 Th''' <br />
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* '''May-24 Fr'''<br />
<br />
2024 Week 22<br />
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* '''May-27 Mo'''<br />
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* '''May-28 Tu''' <br />
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* '''May-29 We''' <br />
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* '''May-30 Th''' <br />
----<br />
* '''May-31 Fr'''<br />
<br />
2024 Week 23<br />
<br />
* '''Jun-03 Mo'''<br />
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* '''Jun-04 Tu''' <br />
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* '''Jun-05 We''' <br />
----<br />
* '''Jun-06 Th''' <br />
----<br />
* '''Jun-07 Fr'''<br />
<br />
2024 Week 24<br />
<br />
* '''Jun-10 Mo'''<br />
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* '''Jun-11 Tu''' <br />
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* '''Jun-12 We''' <br />
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* '''Jun-13 Th''' <br />
----<br />
* '''Jun-14 Fr'''<br />
<br />
2024 Week 25<br />
<br />
* '''Jun-17 Mo'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
<br />
----<br />
* '''Jun-18 Tu''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-19 We''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-20 Th''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-21 Fr'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
<br />
2024 Week 26<br />
<br />
* '''Jun-24 Mo'''<br />
----<br />
* '''Jun-25 Tu''' <br />
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* '''Jun-26 We''' <br />
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* '''Jun-27 Th''' <br />
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* '''Jun-28 Fr'''<br />
<br />
<br />
2024 Week 27<br />
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* '''Jul-01 Mo'''<br />
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* '''Jul-02 Tu''' <br />
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* '''Jul-03 We''' <br />
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* '''Jul-04 Th''' <br />
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* '''Jul-05 Fr'''<br />
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2024 Week 28<br />
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* '''Jul-08 Mo'''<br />
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* '''Jul-09 Tu''' <br />
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* '''Jul-10 We''' <br />
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* '''Jul-11 Th''' <br />
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* '''Jul-12 Fr'''<br />
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2024 Week 29<br />
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* '''Jul-15 Mo'''<br />
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* '''Jul-16 Tu''' <br />
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* '''Jul-17 We''' <br />
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* '''Jul-18 Th''' <br />
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* '''Jul-19 Fr'''<br />
<br />
2024 Week 30<br />
<br />
* '''Jul-22 Mo'''<br />
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* '''Jul-23 Tu''' <br />
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* '''Jul-24 We''' <br />
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* '''Jul-25 Th''' <br />
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* '''Jul-26 Fr'''<br />
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2024 Week 31<br />
<br />
* '''Jul-29 Mo'''<br />
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* '''Jul-30 Tu''' <br />
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* '''Jul-31 We''' <br />
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* '''Aug-01 Th''' <br />
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* '''Aug-02 Fr'''<br />
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2024 Week 32<br />
<br />
* '''Aug-05 Mo'''<br />
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* '''Aug-06 Tu''' <br />
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* '''Aug-07 We''' <br />
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* '''Aug-08 Th''' <br />
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* '''Aug-09 Fr'''<br />
<br />
2024 Week 33<br />
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* '''Aug-12 Mo'''<br />
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* '''Aug-13 Tu''' <br />
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* '''Aug-14 We''' <br />
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* '''Aug-15 Th''' <br />
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* '''Aug-16 Fr'''<br />
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2024 Week 34<br />
<br />
* '''Aug-19 Mo'''<br />
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* '''Aug-20 Tu''' <br />
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* '''Aug-21 We''' <br />
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* '''Aug-22 Th''' <br />
----<br />
* '''Aug-23 Fr'''<br />
<br />
2024 Week 35<br />
<br />
* '''Aug-26 Mo'''<br />
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* '''Aug-27 Tu''' <br />
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* '''Aug-28 We''' <br />
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* '''Aug-29 Th''' <br />
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* '''Aug-30 Fr'''<br />
<br />
2024 Week 36<br />
<br />
* '''Sep-02 Mo'''<br />
----<br />
* '''Sep-03 Tu''' <br />
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* '''Sep-04 We''' <br />
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* '''Sep-05 Th''' <br />
----<br />
* '''Sep-06 Fr'''<br />
<br />
2024 Week 37<br />
<br />
* '''Sep-09 Mo'''<br />
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* '''Sep-10 Tu''' <br />
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* '''Sep-11 We''' <br />
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* '''Sep-12 Th''' <br />
----<br />
* '''Sep-13 Fr'''<br />
<br />
2024 Week 38<br />
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* '''Sep-16 Mo'''<br />
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* '''Sep-17 Tu''' <br />
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* '''Sep-18 We''' <br />
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* '''Sep-19 Th''' <br />
----<br />
* '''Sep-20 Fr'''<br />
<br />
2024 Week 39<br />
<br />
* '''Sep-22 Su'''<br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
* '''Sep-23 Mo'''<br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-24 Tu''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-25 We''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-26 Th''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-27 Fr'''<br />
<br />
<br />
2024 Week 40<br />
<br />
* '''Sep-30 Mo'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-01 Tu''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-02 We''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-03 Th''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-04 Fr'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
<br />
2024 Week 41<br />
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* '''Okt-07 Mo'''<br />
----<br />
* '''Okt-08 Tu''' <br />
----<br />
* '''Okt-09 We''' <br />
----<br />
* '''Okt-10 Th''' <br />
----<br />
* '''Okt-11 Fr'''<br />
<br />
2024 Week 42<br />
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2024 Week 43<br />
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* '''Okt-23 We''' <br />
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* '''Okt-24 Th''' <br />
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* '''Okt-25 Fr'''<br />
::::: <big> '''[[14th Mitochondrial Disease Conference 2024 Padova IT]]'''</big> 2024 Oct 25-27<br />
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2024 Week 44<br />
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* '''Okt-28 Mo'''<br />
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* '''Okt-29 Tu''' <br />
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* '''Okt-30 We''' <br />
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* '''Okt-31 Th''' <br />
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* '''Nov-01 Fr''' <br />
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2024 Week 45<br />
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* '''Nov-06 We''' <br />
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* '''Nov-07 Th''' <br />
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* '''Nov-08 Fr'''<br />
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2024 Week 46<br />
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* '''Nov-14 Th''' <br />
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* '''Nov-15 Fr'''<br />
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2024 Week 47<br />
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* '''Nov-21 Th''' <br />
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* '''Nov-22 Fr'''<br />
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2024 Week 48<br />
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* '''Nov-25 Mo'''<br />
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* '''Nov-29 Fr'''<br />
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2024 Week 49<br />
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2024 Week 50<br />
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* '''Dez-10 Tu''' <br />
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* '''Dez-11 We''' <br />
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* '''Dez-12 Th''' <br />
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* '''Dez-13 Fr'''<br />
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2024 Week 51<br />
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* '''Dez-16 Mo'''<br />
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* '''Dez-18 We''' <br />
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* '''Dez-19 Th''' <br />
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* '''Dez-20 Fr'''<br />
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2024 Week 52<br />
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* '''Dez-23 Mo'''<br />
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* '''Dez-24 Tu''' <br />
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* '''Dez-25 We''' <br />
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* '''Dez-26 Th''' <br />
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* '''Dez-27 Fr'''</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Current_week_ecosystem_agenda&diff=246417
Template:Current week ecosystem agenda
2024-03-11T07:43:31Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:Science for Ukraine}}<br />
2024 Week 11<br />
<br />
* '''Mar-11 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
----<br />
* '''Mar-12 Tu''' <br />
----<br />
* '''Mar-13 We''' <br />
:{|<br />
| width="100" align="center" |[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''''Rewarded'' Open Access - compensating authors'''<br><br />
Together with the MiP''society'', BEC is raising funds to reward the first 10 papers accepted for publication in BEC in 2024: 600 EUR to attend EBEC2024 and 2-year MiP''membership''.<br />
-»[https://whydonate.com/en/fundraising/BEC Support open access in science]«<br><br />
- »[https://www.bioenergetics-communications.org/index.php/bec/about/submissions Submit a manuscript]«<br />
|}<br />
----<br />
* '''Mar-14 Th'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|} <br />
----<br />
* '''Mar-15 Fr''' <br />
----<br />
<br />
'''<big>Next Week</big>'''<br />
2024 Week 12<br />
<br />
* '''Mar-18 Mo'''<br />
::::: '''[[EU-METAHEART MC2 Meeting 2024 Antalya TR]]''' Mar 18-21<br />
----<br />
* '''Mar-19 Tu''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' What if ''Alert: Error in titrations!'' appears in your O2 analysis template file? '''<br><br />
The O2 analysis template recognizes discrepancies between the protocol selected in the first tab and the imported marks. Check the titration sequence and mark names against the protocol copied from the DLD file.<br><br />
- »'''[[MiPNet24.06 Oxygen flux analysis - DatLab 7.4|O<sub>2</sub> flux analysis]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Mar-20 We''' <br />
<br />
----<br />
* '''Mar-21 Th''' <br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you handle well your Hamilton syringes? What is a cleaning cycle?'''<br><br />
"A syringe cleaning cycle consists of filling an empty syringe with a washing solution while immersing [...] also the base of the barrel into the washing solution, without fully removing the plunger, and emptying the syringe into the waste beaker". <br><br />
- »'''[[MiPNet19.14 SOP Hamilton microsyringes]]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
----<br />
* '''Mar-22 Fr'''<br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Oroboros_Ecosystem_Agenda_2024_Archive&diff=246416
Oroboros Ecosystem Agenda 2024 Archive
2024-03-11T07:41:20Z
<p>Tindle Lisa: </p>
<hr />
<div>{{OROBOROS header page name}}<br />
<br />
{{Template:OROBOROS Slogan}}<br />
<br />
::::<big>» [[OROBOROS INSTRUMENTS|Current Oroboros Ecosystem Agenda ]]</big><br />
<br />
__TOC__<br />
<br />
== Last week ==<br />
2024 Week 10<br />
<br />
* '''Mar-04 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test? '''<br><br />
Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.<br />
<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
* '''Mar-05 Tu''' <br />
----<br />
* '''Mar-06 We''' <br />
:{|<br />
| width="100" align="center" |[[File:BEC2024.1.jpg|right|150px|link=https://doi.org/10.26124/bec:2024-0001 |Gross 2024 BEC]]<br />
|'''The tale of two “best-friends,” proteins BID & MTCH2, pivotal regulators of the apoptosis and metabolism programs at the mitochondria.''' <br><br />
* Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001<br />
|}<br />
----<br />
* '''Mar-07 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Which medium can be used for the instrumental background test?'''<br><br />
When using dithionite, the instrumental background test should be performed in mitochondrial respiration medium MiR05, MiR05-Kit or MiR06; or alternatively, in a strong alkaline phosphate buffer (>100 mM; >pH 8), to avoid side reactions that might interfere with the test.<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background]]'''«<br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
----<br />
* '''Mar-08 Fr''' <br />
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<br />
<br />
== Feb 2024 ==<br />
2024 Week 06<br />
<br />
* '''Feb-05 Mo'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"We demonstrated deficient platelet mitochondrial respiratory chain functions, oxidative phosphorylation (OXPHOS), and electron transfer (ET) capacity with complex I (CI)-linked substrates, and reduced [...] endogenous platelet coenzyme Q10 (CoQ10) concentration in UC [urothelial carcinoma] patients."''' <br><br />
* Palacka P, Gvozdjáková A, Rausová Z, Kucharská J, Slopovský J, Obertová J, Furka D, Furka S, Singh KK, Sumbalová Z (2021) Platelet mitochondrial bioenergetics reprogramming in patients with urothelial carcinoma. [[Palacka 2021 Int J Mol Sci|»Bioblast link«]]<br />
:from the O2k-Network »[[SK Bratislava Sumbalova Z]]«<br />
|}<br />
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* '''Feb-06 Tu''' <br />
----<br />
* '''Feb-07 We''' <br />
----<br />
* '''Feb-08 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Can I use the same stock solutions for all reagents for different O2k-chamber volumes?'''<br><br />
For some reagents, the concentration of the stock solution differs between the 2.0-mL and the 0.5-mL chamber (O2k-sV-Module) to facilitate a precise volume titration.<br><br />
-»'''[[MiPNet09.12 O2k-Titrations]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Feb-09 Fr''' <br />
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* '''Feb-10 Sa'''<br />
[[File:Year of the Dragon.jpg|400px]] [[File:ChineseNewYear2024 Taiwan.jpg|400px]]<br><br />
<br />
2024 Week 07<br />
<br />
* '''Feb-12 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' What is the O<sub>2</sub> solubility factor of the medium (''F''<sub>M</sub>) and why is it important? '''<br><br />
''F''<sub>M</sub> expresses the effect of the salt concentration on oxygen solubility relative to pure water, and varies depending on the temperature and composition of the medium. The correct ''F''<sub>M</sub> needs to be entered in DatLab when performing an air calibration. <br><br />
- »'''[[Oxygen solubility factor]]'''« , »'''[[Oxygen_calibration_-_DatLab#Air_calibration_in_DatLab|Air calibration in DatLab]]'''« <br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Feb-13 Tu''' <br />
----<br />
* '''Feb-14 We''' <br />
----<br />
* '''Feb-15 Th''' - International Childhood Cancer Day<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Deleterious mtDNA mutations contribute significantly to the tumorigenesis of pediatric cancers"''' <br><br />
* Triska P, Kaneva K, Merkurjev D, Sohail N, Falk MJ, Triche TJ Jr, Biegel JA, Gai X (2019) Landscape of germline and somatic mitochondrial DNA mutations in pediatric malignancies. [[Triska 2019 Cancer Res|»Bioblast link«]]<br />
:from the O2k-Network »[[US_PA_Philadelphia_Falk_MJ]]«<br />
|}<br />
----<br />
* '''Feb-16 Fr''' <br />
----<br />
2024 Week 08<br />
<br />
* '''Feb-19 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“We just published this paper on [https://academic.oup.com/biomedgerontology/advance-article/doi/10.1093/gerona/glad283/7502466 SOMMA], possibly one of the largest aging studies involving permeabilized muscle energetics. Couldn't have done it without the training your teams provided.”'''''<br><br />
'''[[Kramer Philip A]]''' from the O2k-Network Lab »[[US NC Winston-Salem Kramer PA]]«<br><br />
- »'''[https://wiki.oroboros.at/index.php/O2k-Feedback#More_O2k-Feedback| O2k-Feedback]'''«<br><br />
|}<br />
----<br />
* '''Feb-20 Tu''' <br />
----<br />
* '''Feb-21 We''' <br />
----<br />
* '''Feb-22 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''What to do if the glass of the O2k-chamber starts to become opaque?'''<br><br />
"Turbidity on the glass wall may be caused by precipitated protein. Remove the chambers from the O2k and with the O2k-stirrers removed, immerse in a beaker filled with HCl (10 M) overnight under a hood." <br><br />
-»'''[[MiPNet19.03_O2k-cleaning_and_ISS]]'''«<br><br />
- communicated by »[[Cardoso Luiza]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Feb-23 Fr''' <br />
----<br />
2024 Week 09<br />
<br />
* '''Feb-26 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' ATP synthase = phosphorylation system? '''<br><br />
No, the phosphorylation system consists of adenine nucleotide translocase, phosphate carrier, and ATP synthase, which carry out the steps in the phosphorylation pathway. <br><br />
- »'''[[Phosphorylation pathway]]'''«, »'''[https://www.bioblast.at/index.php/Gnaiger_2020_BEC_MitoPathways Mitochondrial Pathways: Chapter 2.2]'''« <br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Feb-27 Tu''' <br />
----<br />
* '''Feb-28 We''' <br />
----<br />
* '''Feb-29 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Bed rest results in a decrease in skeletal muscle mitochondrial respiratory capacity, mainly as a result of an observed decrease in mitochondrial content"''' <br><br />
* Noone J, Damiot A, Kenny H, Chery I, Zahariev A, Normand S, Crampes F, de Glisezinski I, Rochfort KD, Laurens C, Bareille MP, Simon C, Bergouignan A, Blanc S, O'Gorman DJ (2023) The impact of 60 days of -6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics. [[Noone 2023 J Physiol|»Bioblast link«]]<br />
:from the O2k-Networks »[[US FL Orlando Goodpaster BH]]« , »[[FR Strasbourg Blanc S]]« , »[[IE Dublin O Gorman D]]«<br />
|}<br />
----<br />
* '''Mar-01 Fr''' <br />
----<br />
<br />
== Jan 2024 ==<br />
2024 Week 01<br />
* '''Jan-01 Mo'''<br />
----<br />
* '''Jan-02 Tu'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' New year, new state? What is REN state? '''<br><br />
REN state is now distinguished from ROX state: REN is measured in mitochondrial preparations without addition of substrates, whereas ROX is due to oxidative side reactions remaining after inhibition of the electron transfer pathway. <br> <br />
- »'''[[Residual endogenous substrates|REN]]'''«, »'''[[Residual oxygen consumption|ROX]]'''« <br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]« <br />
|} <br />
----<br />
* '''Jan-03 We''' <br />
----<br />
* '''Jan-04 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Oxygen Consumption Rate (OCR) measurements of fresh and cryopreserved placental specimens are comparable whereas snap frozen procedure impairs mitochondrial activity"''' <br><br />
* Giovarelli M, Serati A, Zecchini S, Guelfi F, Clementi E, Mandò C (2023) Cryopreserved placental biopsies maintain mitochondrial activity for high-resolution respirometry. [[Giovarelli 2023 Mol Med|»Bioblast link«]]<br />
:from the O2k-Network »[[IT Milan Clementi E]]«<br />
|}<br />
----<br />
* '''Jan-05 Fr'''<br />
-----<br />
2024 Week 02<br />
<br />
* '''Jan-08 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Do you need to export DatLab traces for your publication? '''<br><br />
Save your graph as an editable picture using "Copy to clipboard" in DatLab 7.4 (.wmf) or "Save" in DatLab 8 (.svg).<br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/Copy_to_clipboard Copy to clipboard in DatLab 7]'''«, »'''[https://www.oroboros.at/index.php/product/datlab/ Download DatLab 8]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
----<br />
* '''Jan-09 Tu''' <br />
----<br />
* '''Jan-10 We'''<br />
:::: '''»[[AICBC 2024 Navi Mumbai IN]]«''' Jan 10-12<br />
----<br />
* '''Jan-11 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''What are special features of the new SmartPOS (O2k-Series J and NextGen-O2k-Series XB)?'''<br><br />
- "The electrical connections of the SmartPOS are protected thus there is no need to clean them."<br> <br />
- "The serial number of the SmartPOS is automatically recognized by the DatLab 8 software."<br><br />
<br />
»'''[[MiPNet28.10 SmartPOS-service]]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
* '''Jan-12 Fr'''<br />
----<br />
2024 Week 03<br />
<br />
* '''Jan-15 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why electron transfer pathway and not electron transfer chain? '''<br><br />
The term “chain” suggests a linear sequence, however, the convergence of electron flow at the Q-junction indicates a higher degree of complexity, making “pathway” a more fitting descriptor. <br><br />
- »'''[[Electron transfer pathway]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''« <br><br />
- communicated by »[[Leo Elettra]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Jan-16 Tu''' <br />
----<br />
* '''Jan-17 We''' <br />
----<br />
* '''Jan-18 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''The study on rats by Jedlička et al indicates that "...the concept of general pattern of age-dependent decline in mitochondrial oxygen consumption across different organs and tissues could be misleading."''' <br><br />
*Jedlička J, Tůma Z, Razak K, Kunc R, Kala A, Proskauer Pena S, Lerchner T, Ježek K, Kuncová J (2022) Impact of aging on mitochondrial respiration in various organs. [[Jedlicka_2022a_Physiol_Res|»Bioblast link«]]<br />
:from the O2k-Network »[[CZ_Pilsen_Kuncova_J]]«<br />
|}<br />
----<br />
* '''Jan-19 Fr'''<br />
----<br />
2024 Week 04<br />
<br />
* '''Jan-22 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“We are truly glad to have your continued support and partnership.”'''''<br><br />
'''[[Lu Amelia]]''' from the O2k-Network Lab »[[TW Taoyuan Sunpoint]]«<br><br />
- »'''[https://wiki.oroboros.at/index.php/O2k-Feedback#More_O2k-Feedback| O2k-Feedback]'''«<br><br />
|}<br />
----<br />
* '''Jan-23 Tu''' <br />
----<br />
* '''Jan-24 We''' <br />
----<br />
* '''Jan-25 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''How do I view and change the settings of a measurement/file in DatLab 8?'''<br><br />
"O2k control (active) will always show the settings of the active recording [and allow changes], while O2k info (view) will show the settings of the recorded selected file."<br><br />
<br />
-»'''[[MiPNet28.07 NextGen-O2k Series XB manual]]'''«; »'''[[MiPNet28.08 Oroboros O2k Series J manual]]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
----<br />
* '''Jan-26 Fr''' <br />
----<br />
2024 Week 05<br />
* '''Jan-29 Mo'''<br />
:::: '''»[[E-mit Winter School 2024 Brixen IT]]«''' Jan 28 - Feb 02<br />
----<br />
* '''Jan-30 Tu'''<br />
:::: '''16:30 [[Gnaiger Erich|Erich Gnaiger]] presenting at [[E-mit Winter School 2024 Brixen IT]]''' - ''Coupling control and pathway control in mitochondrial high-resolution respirometry''<br />
----<br />
* '''Jan-31 We''' <br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Can the S-pathway O<sub><small>2</small></sub> flux be derived by subtracting N-pathway O<sub><small>2</small></sub> flux from NS-pathway O<sub><small>2</small></sub> flux?'''<br><br />
No, the sum of the O<sub><small>2</small></sub> fluxes measured in the presence of NADH-linked substrates alone and succinate as the single substrate is typically higher than using a combination of all these substrates. This effect is described as incomplete additivity: <br><br />
- »'''[[Additive effect of convergent electron flow]]'''« <br><br />
- communicated by »[[Cardoso Luiza]]« and »[[Grings Mateus]]« <br />
|}<br />
----<br />
* '''Feb-01 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“Doing the entire hands-on module from start to finish was the best for really “cementing” theory and hands-on application together.”'''''<br><br />
[[Cosgrove Richard]] from Eli Lilly Research Labs, on what he liked best on [[IOC162]]<br><br />
- »'''[[O2k-Feedback]]'''«<br><br />
|}<br />
----<br />
* '''Feb-02 Fr''' <br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Current_week_ecosystem_agenda&diff=246402
Template:Current week ecosystem agenda
2024-03-07T17:02:08Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:Science for Ukraine}}<br />
2024 Week 10<br />
<br />
* '''Mar-04 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test? '''<br><br />
Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.<br />
<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
* '''Mar-05 Tu''' <br />
----<br />
* '''Mar-06 We''' <br />
:{|<br />
| width="100" align="center" |[[File:BEC2024.1.jpg|right|150px|link=https://doi.org/10.26124/bec:2024-0001 |Gross 2024 BEC]]<br />
|'''The tale of two “best-friends,” proteins BID & MTCH2, pivotal regulators of the apoptosis and metabolism programs at the mitochondria.''' <br><br />
* Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001<br />
|}<br />
----<br />
* '''Mar-07 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Which medium can be used for the instrumental background test?'''<br><br />
When using dithionite, the instrumental background test should be performed in mitochondrial respiration medium MiR05, MiR05-Kit or MiR06; or alternatively, in a strong alkaline phosphate buffer (>100 mM; >pH 8), to avoid side reactions that might interfere with the test.<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background]]'''«<br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
----<br />
* '''Mar-08 Fr''' <br />
----<br />
<br />
'''<big>Next Week</big>'''<br />
2024 Week 11<br />
<br />
* '''Mar-11 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
----<br />
* '''Mar-12 Tu''' <br />
----<br />
* '''Mar-13 We''' <br />
:{|<br />
| width="100" align="center" |[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''''Rewarded'' Open Access - compensating authors'''<br><br />
Together with the MiP''society'', BEC is raising funds to reward the first 10 papers accepted for publication in BEC in 2024: 600 EUR to attend EBEC2024 and 2-year MiP''membership''.<br />
-»[https://whydonate.com/en/fundraising/BEC Support open access in science]«<br><br />
- »[https://www.bioenergetics-communications.org/index.php/bec/about/submissions Submit a manuscript]«<br />
|}<br />
----<br />
* '''Mar-14 Th'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|} <br />
----<br />
* '''Mar-15 Fr''' <br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Mitochondrial_Physiology_Society&diff=246371
Mitochondrial Physiology Society
2024-03-06T16:50:18Z
<p>Tindle Lisa: </p>
<hr />
<div>{{MiP_navigation_line}}<br />
<div style="font-size:15px;font-weight:bold;;color:#005199;padding:5px;border-bottom:1px solid #aaaaaa;text-align:left;margin:0px;"><br />
<big><big>'''{{FULLPAGENAME}}'''</big></big><br />
</div><br />
[[Image:MiPsocietyLOGO.JPG|right|400px|link=https://www.mitophysiology.org|MiP''society'']]<br />
<br />
<br/><br />
__TOC__<br />
<br />
== News ==<br />
[[File:BEC Image for crowdfoundingproject.jpg|left|500px|link=https://whydonate.com/en/fundraising/BEC]]<br />
:::: <big>'''''Rewarded Open Access'' - compensating authors for their hard work.'''</big><br />
<br />
::::Together with our associated journal, [https://www.bioenergetics-communications.org Bioenergetics Communications], the MiP''society'' is raising funds to reward authors of the first 10 papers accepted for publication in BEC in 2024: 600 EUR award to attend the [https://www.ebe2024.org European Bioenergetics Conference - EBEC2024] and a free MiP''membership''.<br />
::::::<big>»[https://whydonate.com/en/fundraising/BEC '''Donate''']«</big><br />
::::::<big>»[https://www.bioenergetics-communications.org/index.php/bec/about/submissions '''Submit a manuscript''']«</big><br />
<br><br><br />
== MiP''society'' == <br />
::::The MiP''society'' has become a legal body in 2011 continuing a tradition of rigorous mitochondrial bioenergetics; integrating molecular, cellular and organismic physiology and pathology.<br />
<br />
::::The '''Mitochondrial Physiology Society''' ([[MiPSociety|MiP''society'']]) has been founded at the Third Conference on Mitochondrial Physiology (MiP2003), to organize MiP Conferences and Workshops. These MiP''events'' focus on common and cell-specific functions of mitochondria at molecular, organelle, cellular, tissue and organ levels. Thus we meet the increasing demands for integrating current developments in the methodologically and conceptually complex field of mitochondrial physiology. Mitochondrial research has undergone a dramatic renaissance, due to a whole series of discoveries revealing its central roles in cell death, disease pathology, aging, thermogenesis, oxidative stress, cell signalling, cellular regulation and cell bioenergetics. Functional genomics and proteomics is putting an urgent emphasis on integrative understanding of the link between genes/molecules and cellular/organisms functions. Because these topics require continuous technical advances there is also an emphasis on new methodological developments, quantitative methods of analysis in mitochondrial research including mathematical modeling, proteomics and the use of tools for measuring multiple parameters in an experiment. The Mitochondrial Physiology Society provides a multidisciplinary forum for high-level training courses, bringing together scientists working in divergent disciplines, to talk together about mitochondrial function and dysfunction, to resolve differences, to develop research agendas, to spread new knowledge and techniques, and to develop collaborations.<br />
<br />
::::Until the foundation of MiPs, mitochondrial respiratory function was mainly studied in research laboratories specializing on the bioenergetics of isolated mitochondria and bacteria, energy transformation in transmembrane gradients and characterization of the various complexes of the electron transfer-pathway. These methods and concepts are expanded to applications on intact or permeablized cells and tissue preparations, and are widely used by groups with different research and clinical orientation, particularly in molecular cell signalling. MiP''events'' help to provide the expertise necessary for successful application of the techniques and concepts on mitochondrial physiology in the wider context of molecular and cell biology, exercise physiology, diagnosis of mitochondrial diseases, and evaluation of mitochondrial function in oxidative stress, ischemia-reperfusion, aging and degenerative diseases, and numerous areas of key-involvement of mitochondria.<br />
<br />
::::* Until [[MiP2010]], participants of a MiP''conferences'' or other MiP''events'' (MiP''summer'' Schools) were enlisted as MiP''members''. The MiP''society'' has become a legal body in 2011. MiP''membership'' is now becoming established on the basis of membership fees in line with other scientific organizations.<br />
::::* To receive MiP''circulars'', please join the MiP''list''.<br />
<br />
=== Become a MiP''member'' ===<br />
:::: [[MiP membership|MiP''member'' - Information about MiP''membership'']]<br />
<br />
<br />
=== MiP''membership'' list 2024 === <br />
<br />
</div><br />
</div><br />
[[File:Expand.png|right|25px|Click to expand or collaps]]<br />
<div class="toccolours mw-collapsible mw-collapsed"><br />
::: '''MiPmembers''' - This list is sorted alphabetically''' - <small>A * denotes lifetime membership.</small><br />
<div class="mw-collapsible-content"><br />
<br />
:::: [[Abele Nadja]]<br />
:::: [[Alan Lukas|Alán Lukáš]]<br />
:::: [[Arnould Thierry]]*<br />
:::: [[Axelrod Christopher L]] - Co-Chair<br />
:::: [[Bajpeyi Sudip]]*<br />
:::: [[Bandmann O|Bandmann Oliver]]*<br />
:::: [[Barkova Daria]]<br />
:::: [[Blier Pierre U]]*<br />
:::: [[Boardman Neoma T]]*<br />
:::: [[Brown Guy C]]*<br />
:::: [[Brunetta Henver Simionato]]<br />
:::: [[Busch Karin]]*<br />
:::: [[Calloway Eleasha]]<br />
:::: [[Canellas da Silva Maria Clara]]<br />
:::: [[Chicco Adam J]]*<br />
:::: [[Chowdhury Soumitra]]<br />
:::: [[Court Sebastien]]<br />
:::: [[Dalton-OReilly Jessica|Dalton-O'Reilly Jessica]]<br />
:::: [[Dlaskova A|Dlaskova Andrea]]*<br />
:::: [[Endlicher Rene]]<br />
:::: [[Fernandez-Vizarra Erika]]<br />
:::: [[Flynn Robert]]<br />
:::: [[Garcia-Roves Pablo Miguel]]*<br />
:::: [[Giordano Luca]]<br />
:::: [[Gnaiger E|Gnaiger Erich ]]* - Chair<br />
:::: [[Granata Cesare]]<br />
:::: [[Gross Atan]]<br />
:::: [[Guerrier Lisa]]<br />
:::: [[Hand SC|Hand Steven C ]] - Treasurer<br />
:::: [[Handler Alyssa]]* <br />
:::: [[Hayashi A|Hayashi Akira]]<br />
:::: [[Holloway Graham P]]<br />
:::: [[Hunarova Natalia|Huňarová Natália]]<br />
:::: [[Irving Brian A]]<br />
:::: [[Iyer Shilpa]]*<br />
:::: [[Izarik Verespejova Andrea|Ižarik Verešpejová Andrea]]<br />
:::: [[Jasinska Joanna|Jasińska Joanna]]<br />
:::: [[Jezek Petr]]*<br />
:::: [[Karabatsiakis Alexander]]<br />
:::: [[Kayastha Pushpalata]]<br />
:::: [[Keijer Jaap]]*<br />
:::: [[Keller Markus A]]<br />
:::: [[Kollberg Gittan]]<br />
:::: [[Kolonics Attila]]<br />
:::: [[Krako N|Krako Jakovljević Nina ]]<br />
:::: [[Laner Verena]]* - General Secretary<br />
:::: [[Leffler M|Leffler Märta]]*<br />
:::: [[Lemieux Helene|Lemieux Hélène]]*<br />
:::: [[Ma Tao]]<br />
:::: [[Mahapatra Gargi]]<br />
:::: [[Moisoi Nicoleta]]*<br />
:::: [[Molina Anthony JA]]<br />
:::: [[Monsalves-Alvarez Matias]]<br />
:::: [[Ocloo A|Ocloo Augustine]]*<br />
:::: [[Othonicar Murilo F]]<br />
:::: [[Owesny Patricia]]<br />
:::: [[Palm Fredrik]]*<br />
:::: [[Palmeira C|Palmeira Carlos ]]<br />
:::: [[Pena Gabriel]]<br />
:::: [[Perez-Ternero Cristina]]<br />
:::: [[Pesta Dominik]]<br />
:::: [[Petrick Heather L]]<br />
:::: [[Phang Howard J]]<br />
:::: [[Piel Sarah]]<br />
:::: [[Plecita-Hlavata L|Plecita-Hlavata Lydie]]*<br />
:::: [[Porter Craig]]*<br />
:::: [[Pytlak Karolina]]<br />
:::: [[Romero Martinez Alejandra]]<br />
:::: [[Rooney Mary]]*<br />
:::: [[Sadler Daniel]]<br />
:::: [[Saleem Ranim]]<br />
:::: [[Saucedo-Rodriguez Maria Jose]]<br />
:::: [[Schoenfeld Peter|Schönfeld Peter]]<br />
:::: [[Shbiro Liat]]<br />
:::: [[Smolkova Katharina]]*<br />
:::: [[Sonveaux P|Sonveaux Pierre]]*<br />
:::: [[Sobotka Lubos]]<br />
:::: [[Stanic Sara]]<br />
:::: [[Stankova Pavla|Staňková Pavla]]<br />
:::: [[Stary Creed]]*<br />
:::: [[Stiles Linsey]]<br />
:::: [[Strich Sophie]]<br />
:::: [[Timon-Gomez Alba]]*<br />
:::: [[Trnka Jan]]<br />
:::: [[Ullrich Volker]]<br />
:::: [[Valencia Ana P]]<br />
:::: [[Van der Stelt Inge|van der Stelt Inge]]<br />
:::: [[Votion Dominique-Marie]]<br />
:::: [[Vujacic-Mirski Ksenija]]<br />
:::: [[Weinberger Klaus M]]<br />
:::: [[Whitcomb Luke A]]<br />
:::: [[Wohlfarter Yvonne]]<br />
:::: [[Wohlwend Martin]]*<br />
:::: [[Yardeni Tal]]<br />
:::: [[Zink Fabian]]<br />
:::: [[Zouhar Petr]]<br />
<br />
</div><br />
</div><br />
<br />
<br />
== MiP''events'' ==<br />
<br />
:::: '''MiP''events''''' focus on common and cell-specific functions of mitochondria at molecular, organelle, cellular, tissue and organ levels. Thus we meet the increasing demands for integrating current developments in the methodologically and conceptually complex field of mitochondrial physiology. Mitochondrial research has undergone a dramatic renaissance, due to a whole series of discoveries revealing its central roles in cell death, disease pathology, aging, thermogenesis, oxidative stress, cell signalling, cellular regulation and cell bioenergetics. Functional genomics and proteomics is putting an urgent emphasis on integrative understanding of the link between genes/molecules and cellular/organismic functions. Because these topics require continuous technical advances there is also an emphasis on new methodological developments, quantitative methods of analysis in mitochondrial research including mathematical modeling, proteomics and the use of tools for measuring multiple parameters in an experiment. The Mitochondrial Physiology Society provides a multidisciplinary forum for high-level training courses, bringing together scientists working in divergent disciplines, to talk together about mitochondrial function and dysfunction, to resolve differences, to develop research agendas, to spread new knowledge and techniques, and to develop collaborations. Until the foundation of MiP, mitochondrial respiratory function was mainly studied in research laboratories specializing on the bioenergetics of isolated mitochondria and bacteria, energy transformation in transmembrane gradients and characterization of the various complexes of the electron transfer-pathway. These methods and concepts are expanded to applications on intact or permeablized cells and tissue preparations, and are widely used by groups with different research and clinical orientation, particularly in molecular cell signalling. MiP''events'' help to provide the expertise necessary for successful application of the techniques and concepts on mitochondrial physiology in the wider context of molecular and cell biology, exercise physiology, diagnosis of mitochondrial diseases, and evaluation of mitochondrial function in oxidative stress, ischemia-reperfusion, aging and degenerative diseases, and numerous areas of key-involvement of mitochondria. <br />
<br/><br />
<br />
</div><br />
</div><br />
[[File:Expand.png|right|25px|Click to expand or collaps]]<br />
<div class="toccolours mw-collapsible mw-collapsed"><br />
::: All MiP''conferences''<br />
<div class="mw-collapsible-content"><br />
<br />
::::*'''[[MiP2023 Obergurgl AT|MiP2023]], Obergurgl AT'''<br />
::::*'''[[MiP2019/MitoEAGLE Belgrade RS|MiP2019]], Belgrade RS'''<br />
::::*'''[[MiP2018]], Jurmala LV'''<br />
::::*'''[[MiP2017]], Hradec Kralove CZ'''<br />
::::*'''[[MiP2015]], Luční Bouda CZ'''<br />
::::*'''[[MiP2014]], Obergurgl AT'''<br />
::::*'''[[MiPNet18.08_MiP2013|MiP2013]], Obergurgl AT'''<br />
::::*'''[[MiP2011]], Bordeaux FR'''<br />
::::*'''[[MiP2010]], Obergurgl AT'''<br />
::::*'''[[MiP2007 Ambleside UK|MiP2007]], Ambleside UK'''<br />
::::*'''[[Gnaiger 2005 Mitochondr Physiol Network MiP2005| MiP2005]], Schroecken AT'''<br />
::::*'''[[MiPNet08.10 MiP2003|MiP2003]], Schroecken AT'''</div><br />
</div><br />
</div><br />
<br />
</div><br />
</div><br />
[[File:Expand.png|right|25px|Click to expand or collaps]]<br />
<div class="toccolours mw-collapsible mw-collapsed"><br />
::: All MiP''schools''<br />
<div class="mw-collapsible-content"><br />
<br />
::::*'''[[MiPschool Obergurgl 2023 |MiP''school'' Obergurgl AT 2023]]'''<br />
::::*'''[[MiPschool Coimbra 2019|MiP''school'' Coimbra PT 2019]]'''<br />
::::*'''[[MiPschool Tromso-Bergen 2018|MiP''school'' Tromsoe NO 2018]]'''<br />
::::*'''[[MiPschool Obergurgl 2017|MiP''school'' Obergurgl 2017]]'''<br />
::::*'''[[MiPschool Greenville 2015|MiP''school'' Greenville 2015]]'''<br />
::::*'''[[MiPschool London 2015|MiP''school'' London 2015]]'''<br />
::::*'''[[MiPschool Cape Town 2015|MiP''school'' Cape Town 2015]]'''<br />
::::*'''[[MiPschool 2013 Copenhagen DK|MiP''school'' Copenhagen DK 2013]]'''<br />
::::*'''[[MiPschool 2012 Cambridge UK|MiP''school'' Cambridge UK 2012]]'''<br />
::::*'''[[MiPschool 2010 Druskininkai LT|MiP''school'' Druskininkai LT 2010]]'''<br />
::::*'''[[MiPschool 2009 Baton Rouge LA US| MiP''school'' Baton Rouge LA US 2009]]'''<br />
::::*'''[[MiPschool Schroecken AT 2008|MiP''school'' Schroecken AT 2008]]'''<br />
::::*'''[[MiPschool 2007 Schroecken AT|MiP''school'' Schroecken AT 2007]]'''</div><br />
</div><br />
</div><br />
<br />
== Executive MiP''committee'' ==<br />
Last election: [[MiP2023 Obergurgl AT]]<br />
::: '''Committee members'''<br />
::::* [[Gnaiger E | Erich Gnaiger]], Innsbruck, Austria; Chair since 2003 - organizer of MiP2003 and 2005, MiP''summer'' 2007, 2008; MiP2010, 2013, MiP2014, MiP''school'' and MiP2023<br />
::::* [[Axelrod Christopher | Christopher Axelrod]], Baton Rouge, USA - Co-chair<br />
::::* [[Hand SC | Steven C Hand]], Baton Rouge, USA; Treasurer since 2010 - organizer of MiP''school'' 2009<br />
::::* [[Chicco AJ| Adam Chicco]], Fort Collins, USA<br />
::::* [[Garcia-Roves PM | Pablo Garcia-Roves]], Barcelona, Spain<br />
::::* [[Holloway Graham P | Graham Holloway]], Guelph, Canada<br />
::::* [[Laner V|Verena Laner]], Innsbruck, Austria; General secretary since 2013. - organizer of MiP2013, MiP2014, MiP2023.<br />
<br />
::: '''Extended MiP''board'' members'''<br />
::::* [[Irving BA | Brian Irving]], Baton Rouge, USA<br />
::::* [[Palmeira C | Carlos Palmeira]] Coimbra, Portugal - organizer of MiP''school''2019<br />
::::* [[Sobotka L | Lubos Sobotka]], Hradec Kralove, Czech Republic<br />
<br />
<br />
<br />
== MiP''fellows''==<br />
<br />
MiP''fellowships'' are based on contributions to the MiP''society'' and function to support the Executive MiP''committee'' in promoting MiP''society'' events and membership.<br />
<br />
::::* [[Sharma Pushpa|Pushpa Sharma]], Uniformed Services University of the Health Sciences, US<br />
<br />
::::* [[Ali Sameh S|Sameh Ali]], Children’s Cancer Hospital, EG<br />
== Honorary members of the MiP''society''==<br />
<br />
{| class="wikitable"<br />
! style="text-align: center;" |[[File:Sir John Walker MiP2013.JPG|center|150px]]<br />
<br />
|Nobel laureate Sir [[Walker JE|John Walker]] (Cambridge MBU, UK; Nobel prize 1997 in chemistry) in Trinity Hall at [[MiPschool Cambridge UK 2012|MiP''summer'' 2012 Cambridge]] (2012-07-10). He has joined the MiP''society'' as the first Honorary Gentle Science Member of the Mitochondrial Physiology Society, following his presentation of The ATP Synthase at the MiPsummer School 2012 on July 10 in Trinity Hall, Cambridge.<br />
|-<br />
|[[File:SkulachevV.jpg|center|150px]] <br />
| Prof. [[Skulachev VP|Vladimir P Skulachev]] was elected as the second 'Honorary Member of the MiP''society''' during [[MiP2015|MiP2015]] at the occasion of his 80th birthday.<br />
|-<br />
|[[File:HoppelC MiP.jpg|center|150px]]<br />
| Prof. [[Hoppel CL |Charles L Hoppel]] was elected as the third 'Honorary Member of the MiP''society''' during the [[MiPschool Obergurgl 2017|MiPschool Obergurgl 2017]]. <br />
|-<br />
| [[File:Zdenek Drahota Honorary MiPmember.jpg|center|150px]]<br />
| Dr. [[Drahota Z|Drahota Zdenek]] was elected as the fourth 'Honorary Member of the MiP''society''' during the [[MiP2017/MitoEAGLE Hradec Kralove CZ|MiP2017/MitoEAGLE Hradec Kralove CZ]].<br />
|}<br />
<br />
<br />
== MiP''society'' general assembly ==<br />
::::The MiP''society'' general assembly takes place within the MiP''conference'' event. The general assembly is made up of the MiP''board'' members, who are presented with a review of the previous year and who are empowered to make the key decision for the continuation of the society.<br />
<br />
::::*Minutes of the MiP General Assembly 2023: [[Media:2023 MiPs General Assembly Minutes signed.pdf|pdf]]<br />
::::*Minutes of the MiP General Assembly 2018: [http://www.mitophysiology.org/images/c/c2/Minutes2018_signed.pdf pdf]<br />
::::*Minutes of the MiP General Assembly 2015: [http://wiki.oroboros.at/images/5/51/MiP_Minutes_of_the_General_Assembly_2015_English.pdf pdf]<br />
::::*Minutes of the MiP General Assembly 2013: [http://wiki.oroboros.at/images/a/a9/MiP_Minutes_of_the_General_Assembly_2013.pdf pdf]<br />
<br/><br />
<br />
=== By-laws ===<br />
::::Registered in Innsbruck, Austria, as a non-governmental organization in 2011.<br />
::::Bylaws available as PDF for [[Media:ByLaws_MiPs_2018-09-19.pdf|download]].<br />
<br/><br />
<br />
<br />
== Further information ==<br />
::::» [[MiPculture|MiP''culture'']]<br />
::::» [[MiPtextbooks|MiP''textbooks'']]<br />
::::» [[MiPliterature|MiP''literature'']]<br />
<br />
<br />
== Contact ==<br />
::::'''[[Gnaiger E|Erich Gnaiger (Chair)]]''', '''[[Laner V|Verena Laner (General Secretary)]]'''<br />
::::'''Postal address'''<br />
::::Schöpfstr. 18<br />
::::6020 Innsbruck, Austria<br />
::::[mailto:society@mitophysiology.org society@mitophysiology.org]</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Mitochondrial_Physiology_Society&diff=246370
Mitochondrial Physiology Society
2024-03-06T16:41:06Z
<p>Tindle Lisa: </p>
<hr />
<div>{{MiP_navigation_line}}<br />
<div style="font-size:15px;font-weight:bold;;color:#005199;padding:5px;border-bottom:1px solid #aaaaaa;text-align:left;margin:0px;"><br />
<big><big>'''{{FULLPAGENAME}}'''</big></big><br />
</div><br />
[[Image:MiPsocietyLOGO.JPG|right|400px|link=https://www.mitophysiology.org|MiP''society'']]<br />
<br />
<br/><br />
__TOC__<br />
<br />
== News ==<br />
[[File:BEC Image for crowdfoundingproject.jpg|left|500px|link=https://whydonate.com/en/fundraising/BEC]]<br />
:::: <big>'''''Rewarded Open Access'' - compensating authors for their hard work.'''</big><br />
<br />
::::Together with our associated journal, [https://www.bioenergetics-communications.org Bioenergetics Communications], the MiP''society'' is raising funds to reward authors of the first 10 papers accepted for publication in BEC in 2024: 600 EUR award to attend the [https://www.ebe2024.org European Bioenergetics Conference - EBEC2024] and a free MiP''membership''.<br />
::::::<big>»[https://whydonate.com/en/fundraising/BEC '''Donate''']«</big><br />
::::::<big>»[https://www.bioenergetics-communications.org/index.php/bec/about/submissions '''Submit a manuscript''']«</big><br />
<br><br><br />
== MiP''society'' == <br />
::::The MiP''society'' has become a legal body in 2011 continuing a tradition of rigorous mitochondrial bioenergetics; integrating molecular, cellular and organismic physiology and pathology.<br />
<br />
::::The '''Mitochondrial Physiology Society''' ([[MiPSociety|MiP''society'']]) has been founded at the Third Conference on Mitochondrial Physiology (MiP2003), to organize MiP Conferences and Workshops. These MiP''events'' focus on common and cell-specific functions of mitochondria at molecular, organelle, cellular, tissue and organ levels. Thus we meet the increasing demands for integrating current developments in the methodologically and conceptually complex field of mitochondrial physiology. Mitochondrial research has undergone a dramatic renaissance, due to a whole series of discoveries revealing its central roles in cell death, disease pathology, aging, thermogenesis, oxidative stress, cell signalling, cellular regulation and cell bioenergetics. Functional genomics and proteomics is putting an urgent emphasis on integrative understanding of the link between genes/molecules and cellular/organisms functions. Because these topics require continuous technical advances there is also an emphasis on new methodological developments, quantitative methods of analysis in mitochondrial research including mathematical modeling, proteomics and the use of tools for measuring multiple parameters in an experiment. The Mitochondrial Physiology Society provides a multidisciplinary forum for high-level training courses, bringing together scientists working in divergent disciplines, to talk together about mitochondrial function and dysfunction, to resolve differences, to develop research agendas, to spread new knowledge and techniques, and to develop collaborations.<br />
<br />
::::Until the foundation of MiPs, mitochondrial respiratory function was mainly studied in research laboratories specializing on the bioenergetics of isolated mitochondria and bacteria, energy transformation in transmembrane gradients and characterization of the various complexes of the electron transfer-pathway. These methods and concepts are expanded to applications on intact or permeablized cells and tissue preparations, and are widely used by groups with different research and clinical orientation, particularly in molecular cell signalling. MiP''events'' help to provide the expertise necessary for successful application of the techniques and concepts on mitochondrial physiology in the wider context of molecular and cell biology, exercise physiology, diagnosis of mitochondrial diseases, and evaluation of mitochondrial function in oxidative stress, ischemia-reperfusion, aging and degenerative diseases, and numerous areas of key-involvement of mitochondria.<br />
<br />
::::* Until [[MiP2010]], participants of a MiP''conferences'' or other MiP''events'' (MiP''summer'' Schools) were enlisted as MiP''members''. The MiP''society'' has become a legal body in 2011. MiP''membership'' is now becoming established on the basis of membership fees in line with other scientific organizations.<br />
::::* To receive MiP''circulars'', please join the MiP''list''.<br />
<br />
=== Become a MiP''member'' ===<br />
:::: [[MiP membership|MiP''member'' - Information about MiP''membership'']]<br />
<br />
<br />
=== MiP''membership'' list 2024 === <br />
<br />
</div><br />
</div><br />
[[File:Expand.png|right|25px|Click to expand or collaps]]<br />
<div class="toccolours mw-collapsible mw-collapsed"><br />
::: '''MiPmembers''' - This list is sorted alphabetically''' - <small>A * denotes lifetime membership.</small><br />
<div class="mw-collapsible-content"><br />
<br />
:::: [[Abele Nadja]]<br />
:::: [[Alan Lukas|Alán Lukáš]]<br />
:::: [[Arnould Thierry]]*<br />
:::: [[Axelrod Christopher L]] - Co-Chair<br />
:::: [[Bajpeyi Sudip]]*<br />
:::: [[Bandmann O|Bandmann Oliver]]*<br />
:::: [[Barkova Daria]]<br />
:::: [[Blier Pierre U]]*<br />
:::: [[Boardman Neoma T]]*<br />
:::: [[Brown Guy C]]*<br />
:::: [[Brunetta Henver Simionato]]<br />
:::: [[Busch Karin]]*<br />
:::: [[Calloway Eleasha]]<br />
:::: [[Canellas da Silva Maria Clara]]<br />
:::: [[Chicco Adam J]]*<br />
:::: [[Chowdhury Soumitra]]<br />
:::: [[Court Sebastien]]<br />
:::: [[Dalton-OReilly Jessica|Dalton-O'Reilly Jessica]]<br />
:::: [[Dlaskova A|Dlaskova Andrea]]*<br />
:::: [[Endlicher Rene]]<br />
:::: [[Fernandez-Vizarra Erika]]<br />
:::: [[Flynn Robert]]<br />
:::: [[Garcia-Roves Pablo Miguel]]*<br />
:::: [[Giordano Luca]]<br />
:::: [[Gnaiger E|Gnaiger Erich ]]* - Chair<br />
:::: [[Granata Cesare]]<br />
:::: [[Gross Atan]]<br />
:::: [[Guerrier Lisa]]<br />
:::: [[Hand SC|Hand Steven C ]] - Treasurer<br />
:::: [[Handler Alyssa]]* <br />
:::: [[Hayashi A|Hayashi Akira]]<br />
:::: [[Holloway Graham P]]<br />
:::: [[Hunarova Natalia|Huňarová Natália]]<br />
:::: [[Irving Brian A]]<br />
:::: [[Iyer Shilpa]]<br />
:::: [[Izarik Verespejova Andrea|Ižarik Verešpejová Andrea]]<br />
:::: [[Jasinska Joanna|Jasińska Joanna]]<br />
:::: [[Jezek Petr]]*<br />
:::: [[Karabatsiakis Alexander]]<br />
:::: [[Kayastha Pushpalata]]<br />
:::: [[Keijer Jaap]]*<br />
:::: [[Keller Markus A]]<br />
:::: [[Kollberg Gittan]]<br />
:::: [[Kolonics Attila]]<br />
:::: [[Krako N|Krako Jakovljević Nina ]]<br />
:::: [[Laner Verena]]* - General Secretary<br />
:::: [[Leffler M|Leffler Märta]]*<br />
:::: [[Lemieux Helene|Lemieux Hélène]]*<br />
:::: [[Ma Tao]]<br />
:::: [[Mahapatra Gargi]]<br />
:::: [[Moisoi Nicoleta]]*<br />
:::: [[Molina Anthony JA]]<br />
:::: [[Monsalves-Alvarez Matias]]<br />
:::: [[Ocloo A|Ocloo Augustine]]*<br />
:::: [[Othonicar Murilo F]]<br />
:::: [[Owesny Patricia]]<br />
:::: [[Palm Fredrik]]*<br />
:::: [[Palmeira C|Palmeira Carlos ]]<br />
:::: [[Pena Gabriel]]<br />
:::: [[Perez-Ternero Cristina]]<br />
:::: [[Pesta Dominik]]<br />
:::: [[Petrick Heather L]]<br />
:::: [[Phang Howard J]]<br />
:::: [[Piel Sarah]]<br />
:::: [[Plecita-Hlavata L|Plecita-Hlavata Lydie]]*<br />
:::: [[Porter Craig]]*<br />
:::: [[Pytlak Karolina]]<br />
:::: [[Romero Martinez Alejandra]]<br />
:::: [[Rooney Mary]]*<br />
:::: [[Sadler Daniel]]<br />
:::: [[Saleem Ranim]]<br />
:::: [[Saucedo-Rodriguez Maria Jose]]<br />
:::: [[Schoenfeld Peter|Schönfeld Peter]]<br />
:::: [[Shbiro Liat]]<br />
:::: [[Smolkova Katharina]]*<br />
:::: [[Sonveaux P|Sonveaux Pierre]]*<br />
:::: [[Sobotka Lubos]]<br />
:::: [[Stanic Sara]]<br />
:::: [[Stankova Pavla|Staňková Pavla]]<br />
:::: [[Stary Creed]]*<br />
:::: [[Stiles Linsey]]<br />
:::: [[Strich Sophie]]<br />
:::: [[Timon-Gomez Alba]]*<br />
:::: [[Trnka Jan]]<br />
:::: [[Ullrich Volker]]<br />
:::: [[Valencia Ana P]]<br />
:::: [[Van der Stelt Inge|van der Stelt Inge]]<br />
:::: [[Votion Dominique-Marie]]<br />
:::: [[Vujacic-Mirski Ksenija]]<br />
:::: [[Weinberger Klaus M]]<br />
:::: [[Whitcomb Luke A]]<br />
:::: [[Wohlfarter Yvonne]]<br />
:::: [[Wohlwend Martin]]*<br />
:::: [[Yardeni Tal]]<br />
:::: [[Zink Fabian]]<br />
:::: [[Zouhar Petr]]<br />
<br />
</div><br />
</div><br />
<br />
<br />
== MiP''events'' ==<br />
<br />
:::: '''MiP''events''''' focus on common and cell-specific functions of mitochondria at molecular, organelle, cellular, tissue and organ levels. Thus we meet the increasing demands for integrating current developments in the methodologically and conceptually complex field of mitochondrial physiology. Mitochondrial research has undergone a dramatic renaissance, due to a whole series of discoveries revealing its central roles in cell death, disease pathology, aging, thermogenesis, oxidative stress, cell signalling, cellular regulation and cell bioenergetics. Functional genomics and proteomics is putting an urgent emphasis on integrative understanding of the link between genes/molecules and cellular/organismic functions. Because these topics require continuous technical advances there is also an emphasis on new methodological developments, quantitative methods of analysis in mitochondrial research including mathematical modeling, proteomics and the use of tools for measuring multiple parameters in an experiment. The Mitochondrial Physiology Society provides a multidisciplinary forum for high-level training courses, bringing together scientists working in divergent disciplines, to talk together about mitochondrial function and dysfunction, to resolve differences, to develop research agendas, to spread new knowledge and techniques, and to develop collaborations. Until the foundation of MiP, mitochondrial respiratory function was mainly studied in research laboratories specializing on the bioenergetics of isolated mitochondria and bacteria, energy transformation in transmembrane gradients and characterization of the various complexes of the electron transfer-pathway. These methods and concepts are expanded to applications on intact or permeablized cells and tissue preparations, and are widely used by groups with different research and clinical orientation, particularly in molecular cell signalling. MiP''events'' help to provide the expertise necessary for successful application of the techniques and concepts on mitochondrial physiology in the wider context of molecular and cell biology, exercise physiology, diagnosis of mitochondrial diseases, and evaluation of mitochondrial function in oxidative stress, ischemia-reperfusion, aging and degenerative diseases, and numerous areas of key-involvement of mitochondria. <br />
<br/><br />
<br />
</div><br />
</div><br />
[[File:Expand.png|right|25px|Click to expand or collaps]]<br />
<div class="toccolours mw-collapsible mw-collapsed"><br />
::: All MiP''conferences''<br />
<div class="mw-collapsible-content"><br />
<br />
::::*'''[[MiP2023 Obergurgl AT|MiP2023]], Obergurgl AT'''<br />
::::*'''[[MiP2019/MitoEAGLE Belgrade RS|MiP2019]], Belgrade RS'''<br />
::::*'''[[MiP2018]], Jurmala LV'''<br />
::::*'''[[MiP2017]], Hradec Kralove CZ'''<br />
::::*'''[[MiP2015]], Luční Bouda CZ'''<br />
::::*'''[[MiP2014]], Obergurgl AT'''<br />
::::*'''[[MiPNet18.08_MiP2013|MiP2013]], Obergurgl AT'''<br />
::::*'''[[MiP2011]], Bordeaux FR'''<br />
::::*'''[[MiP2010]], Obergurgl AT'''<br />
::::*'''[[MiP2007 Ambleside UK|MiP2007]], Ambleside UK'''<br />
::::*'''[[Gnaiger 2005 Mitochondr Physiol Network MiP2005| MiP2005]], Schroecken AT'''<br />
::::*'''[[MiPNet08.10 MiP2003|MiP2003]], Schroecken AT'''</div><br />
</div><br />
</div><br />
<br />
</div><br />
</div><br />
[[File:Expand.png|right|25px|Click to expand or collaps]]<br />
<div class="toccolours mw-collapsible mw-collapsed"><br />
::: All MiP''schools''<br />
<div class="mw-collapsible-content"><br />
<br />
::::*'''[[MiPschool Obergurgl 2023 |MiP''school'' Obergurgl AT 2023]]'''<br />
::::*'''[[MiPschool Coimbra 2019|MiP''school'' Coimbra PT 2019]]'''<br />
::::*'''[[MiPschool Tromso-Bergen 2018|MiP''school'' Tromsoe NO 2018]]'''<br />
::::*'''[[MiPschool Obergurgl 2017|MiP''school'' Obergurgl 2017]]'''<br />
::::*'''[[MiPschool Greenville 2015|MiP''school'' Greenville 2015]]'''<br />
::::*'''[[MiPschool London 2015|MiP''school'' London 2015]]'''<br />
::::*'''[[MiPschool Cape Town 2015|MiP''school'' Cape Town 2015]]'''<br />
::::*'''[[MiPschool 2013 Copenhagen DK|MiP''school'' Copenhagen DK 2013]]'''<br />
::::*'''[[MiPschool 2012 Cambridge UK|MiP''school'' Cambridge UK 2012]]'''<br />
::::*'''[[MiPschool 2010 Druskininkai LT|MiP''school'' Druskininkai LT 2010]]'''<br />
::::*'''[[MiPschool 2009 Baton Rouge LA US| MiP''school'' Baton Rouge LA US 2009]]'''<br />
::::*'''[[MiPschool Schroecken AT 2008|MiP''school'' Schroecken AT 2008]]'''<br />
::::*'''[[MiPschool 2007 Schroecken AT|MiP''school'' Schroecken AT 2007]]'''</div><br />
</div><br />
</div><br />
<br />
== Executive MiP''committee'' ==<br />
Last election: [[MiP2023 Obergurgl AT]]<br />
::: '''Committee members'''<br />
::::* [[Gnaiger E | Erich Gnaiger]], Innsbruck, Austria; Chair since 2003 - organizer of MiP2003 and 2005, MiP''summer'' 2007, 2008; MiP2010, 2013, MiP2014, MiP''school'' and MiP2023<br />
::::* [[Axelrod Christopher | Christopher Axelrod]], Baton Rouge, USA - Co-chair<br />
::::* [[Hand SC | Steven C Hand]], Baton Rouge, USA; Treasurer since 2010 - organizer of MiP''school'' 2009<br />
::::* [[Chicco AJ| Adam Chicco]], Fort Collins, USA<br />
::::* [[Garcia-Roves PM | Pablo Garcia-Roves]], Barcelona, Spain<br />
::::* [[Holloway Graham P | Graham Holloway]], Guelph, Canada<br />
::::* [[Laner V|Verena Laner]], Innsbruck, Austria; General secretary since 2013. - organizer of MiP2013, MiP2014, MiP2023.<br />
<br />
::: '''Extended MiP''board'' members'''<br />
::::* [[Irving BA | Brian Irving]], Baton Rouge, USA<br />
::::* [[Palmeira C | Carlos Palmeira]] Coimbra, Portugal - organizer of MiP''school''2019<br />
::::* [[Sobotka L | Lubos Sobotka]], Hradec Kralove, Czech Republic<br />
<br />
<br />
<br />
== MiP''fellows''==<br />
<br />
MiP''fellowships'' are based on contributions to the MiP''society'' and function to support the Executive MiP''committee'' in promoting MiP''society'' events and membership.<br />
<br />
::::* [[Sharma Pushpa|Pushpa Sharma]], Uniformed Services University of the Health Sciences, US<br />
<br />
::::* [[Ali Sameh S|Sameh Ali]], Children’s Cancer Hospital, EG<br />
== Honorary members of the MiP''society''==<br />
<br />
{| class="wikitable"<br />
! style="text-align: center;" |[[File:Sir John Walker MiP2013.JPG|center|150px]]<br />
<br />
|Nobel laureate Sir [[Walker JE|John Walker]] (Cambridge MBU, UK; Nobel prize 1997 in chemistry) in Trinity Hall at [[MiPschool Cambridge UK 2012|MiP''summer'' 2012 Cambridge]] (2012-07-10). He has joined the MiP''society'' as the first Honorary Gentle Science Member of the Mitochondrial Physiology Society, following his presentation of The ATP Synthase at the MiPsummer School 2012 on July 10 in Trinity Hall, Cambridge.<br />
|-<br />
|[[File:SkulachevV.jpg|center|150px]] <br />
| Prof. [[Skulachev VP|Vladimir P Skulachev]] was elected as the second 'Honorary Member of the MiP''society''' during [[MiP2015|MiP2015]] at the occasion of his 80th birthday.<br />
|-<br />
|[[File:HoppelC MiP.jpg|center|150px]]<br />
| Prof. [[Hoppel CL |Charles L Hoppel]] was elected as the third 'Honorary Member of the MiP''society''' during the [[MiPschool Obergurgl 2017|MiPschool Obergurgl 2017]]. <br />
|-<br />
| [[File:Zdenek Drahota Honorary MiPmember.jpg|center|150px]]<br />
| Dr. [[Drahota Z|Drahota Zdenek]] was elected as the fourth 'Honorary Member of the MiP''society''' during the [[MiP2017/MitoEAGLE Hradec Kralove CZ|MiP2017/MitoEAGLE Hradec Kralove CZ]].<br />
|}<br />
<br />
<br />
== MiP''society'' general assembly ==<br />
::::The MiP''society'' general assembly takes place within the MiP''conference'' event. The general assembly is made up of the MiP''board'' members, who are presented with a review of the previous year and who are empowered to make the key decision for the continuation of the society.<br />
<br />
::::*Minutes of the MiP General Assembly 2023: [[Media:2023 MiPs General Assembly Minutes signed.pdf|pdf]]<br />
::::*Minutes of the MiP General Assembly 2018: [http://www.mitophysiology.org/images/c/c2/Minutes2018_signed.pdf pdf]<br />
::::*Minutes of the MiP General Assembly 2015: [http://wiki.oroboros.at/images/5/51/MiP_Minutes_of_the_General_Assembly_2015_English.pdf pdf]<br />
::::*Minutes of the MiP General Assembly 2013: [http://wiki.oroboros.at/images/a/a9/MiP_Minutes_of_the_General_Assembly_2013.pdf pdf]<br />
<br/><br />
<br />
=== By-laws ===<br />
::::Registered in Innsbruck, Austria, as a non-governmental organization in 2011.<br />
::::Bylaws available as PDF for [[Media:ByLaws_MiPs_2018-09-19.pdf|download]].<br />
<br/><br />
<br />
<br />
== Further information ==<br />
::::» [[MiPculture|MiP''culture'']]<br />
::::» [[MiPtextbooks|MiP''textbooks'']]<br />
::::» [[MiPliterature|MiP''literature'']]<br />
<br />
<br />
== Contact ==<br />
::::'''[[Gnaiger E|Erich Gnaiger (Chair)]]''', '''[[Laner V|Verena Laner (General Secretary)]]'''<br />
::::'''Postal address'''<br />
::::Schöpfstr. 18<br />
::::6020 Innsbruck, Austria<br />
::::[mailto:society@mitophysiology.org society@mitophysiology.org]</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:BioblastAlert2024&diff=246369
Template:BioblastAlert2024
2024-03-06T14:33:14Z
<p>Tindle Lisa: </p>
<hr />
<div>__TOC__<br />
<br/><br />
=== Bioblast alert 2024(03) - Respiratory states: 2024-03-06 ===<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|Here is a system of terms and abbreviations for mitochondrial respiratory pathway and coupling control states.<br><br />
Although states and rates are distinguished by different symbols for coupling control states, such a distinction is not suggested for pathway control states and rates to avoid handing and overwhelming number of different symbols.<br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/Pathway_and_coupling_control_states MitoPedia: Pathway and coupling control states]'''«<br />
|}<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Do you know the difference between uncoupled, noncoupled and dyscoupled respiration? '''<br><br />
Noncoupled respiration is induced experimentally for evaluation of ET capacity, while uncoupling and dyscoupling are respectively caused by<br />
physiological and pathological conditions that exert an influence on proton leak and slip. <br><br />
- »'''[[Noncoupled_respiration|Noncoupled respiration]]'''«, »'''[[BEC_2020.1_doi10.26124bec2020-0001.v1|BEC 2020.01]]'''« <br><br />
|}<br />
<br />
:{|<br />
| width="110" align="center" | [[File:Gnaiger 2020 BEC MitoPathways.jpg|70px|link=https://www.bioenergetics-communications.org/index.php/bec/article/view/gnaiger_2020_mitopathways|Gnaiger 2020 BEC MitoPathways]]<br />
|'''What is ROUTINE respiration?'''<br><br />
ROUTINE respiration is the respiratory activity of living (non-permeabilized) cells in the physiological coupling state, which is controlled by cellular energy demand, energy turnover and the degree of coupling to phosphorylation. <br><br />
- »[https://www.bioenergetics-communications.org/index.php/bec/article/view/gnaiger_2020_mitopathways Gnaiger 2020 BEC MitoPathways - Chapter 2.4]« <br><br />
|}<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' What is the limitation of State 3 respiration compared to OXPHOS capacity? '''<br><br />
OXPHOS capacity is defined as the maximal respiratory capacity in the OXPHOS state in the presence of kinetically-saturating concentration of ADP, P<sub>i</sub>, fuel substrates and O<sub>2</sub>. However, State 3 as defined by Chance and Williams (1955) can lead to underestimation of OXPHOS capacity and overestimation of ''E-P'' excess capacity due to kinetic limitations of the phosphorylation system. <br><br />
- »'''[[OXPHOS capacity]]'''«, »'''[[E-P excess capacity]]'''« -<br><br />
-'''[[BEC_2020.1_doi10.26124bec2020-0001.v1|Gnaiger - MitoEAGLE Task Group (2020) Mitochondrial physiology - Table 3]]'''« <br />
|}<br />
----<br />
=== Bioblast alert 2024(02) - Bioenergetics Communications and EBEC2024: 2024-02-15 ===<br />
:{|<br />
| width="100" align="center" |[[File:BEC2024.1.jpg|right|150px|link=https://doi.org/10.26124/bec:2024-0001 |Gross 2024 BEC]]<br />
|'''The tale of two “best-friends,” proteins BID & MTCH2, pivotal regulators of the apoptosis and metabolism programs at the mitochondria.''' <br><br />
* Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001<br />
|}<br />
<br />
:{|<br />
| width="100" align="center" |[[File:EBEC2024 logo nobkg whiteshadow.png|100px|link=https://www.ebec2024.org |EBEC2024]]<br />
|'''EBEC2024 ''What is Life?'' Spotlights on Mito and Chlora:'''<br><br />
Cutting-edge research on mitochondria & chloroplasts, metabolism, and disease<br><br />
'''2024 August 26-31, Innsbruck, Austria'''<br><br />
- »[https://www.ebec2024.org/index.php/registration/ Registration and abstract submission open]« <br />
|}<br />
<br />
:{|<br />
| width="100" align="center" |[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''''Rewarded'' Open Access - compensating authors..'''<br><br />
Together with the MiP''society'', BEC is raising funds to reward the first 10 papers accepted for publication in BEC in 2024: 600 EUR to attend EBEC2024 and 2-year MiP''membership''.<br />
-»[https://whydonate.com/en/fundraising/BEC Support open access in science]«<br><br />
- »[https://www.bioenergetics-communications.org/index.php/bec/about/submissions Submit a manuscript]«<br />
|}<br />
----<br />
=== Bioblast alert 2024(01) - Fatty acid oxidation: 2024-02-08 ===<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Measuring fatty acid oxidation (FAO)-linked respiration requires a low concentration of malate '''<br><br />
In the absence of malate, accumulation of Acetyl-CoA inhibits FAO. <br><br />
- »'''[[Fatty acid oxidation pathway control state]]'''«, »'''[https://www.bioblast.at/index.php/Gnaiger_2020_BEC_MitoPathways Mitochondrial Pathways: Chapter 5]'''« <br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Cardoso Luiza]]« <br />
|}<br />
<br />
:{|<br />
| width="100" align="center" |[[File:MitoFit Preprints.png|100px|link=https://wiki.oroboros.at/images/0/00/Cecatto_2023_MitoFit.pdf |MitoFit pdf]]<br />
|'''"The capacity of FA oxidative phosphorylation (F-OXPHOS) with palmitoylcarnitine was up to 4 times higher than respiration with octanoylcarnitine. The optimal concentration of palmitoylcarnitine was 10 μM which corresponds to the total concentration of LC acylcarnitines in the brain."'''<br><br />
* Cecatto C, Cardoso LHD, Ozola M, Korzh S, Zvejniece L, Gukalova B, Doerrier C, Dambrova M, Gnaiger E, Makrecka-Kuka M, Liepinsh E (2023) Fatty acid β-oxidation in brain mitochondria: Insights from high-resolution respirometry in mouse, rat and Drosophila brain, ischemia and aging models. MitoFit Preprints 2023.10. https://doi.org/10.26124/mitofit:2023-0010<br />
:from the O2k-Network »[[AT Innsbruck Oroboros]]« and »[[LV Riga Liepins E]]«<br />
|}<br />
<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
| '''"... several graphical representations of the electron transfer system depict FADH2 in the mitochondrial matrix as a substrate to be oxidized by CII. This leads to the false conclusion that FADH2 from the β-oxidation cycle in fatty acid oxidation feeds electrons into CII. In reality, dehydrogenases of fatty acid oxidation channel electrons to the Q-junction but not through CII."'''<br><br />
* Gnaiger E (2024) Complex II ambiguities ― FADH2 in the electron transfer system. [[Gnaiger 2024 J Biol Chem|»Bioblast link«]]<br />
:from the O2k-Network »[[AT Innsbruck Oroboros]]« <br />
|}<br />
<br />
:{|<br />
| width="100" align="center" |[[File:BEC2022.15.jpg|right|150px|link=https://doi.org/10.26124/bec:2022-0015 |Dambrova 2022 BEC]]<br />
|'''"Clinically approved cardiovascular and diabetes drugs reduce LC acylcarnitine concentrations in vivo and it would be worth investigating whether these compounds could be repurposed."''' <br><br />
* Dambrova M, Cecatto C, Vilskersts R, Liepinsh E (2022) Mitochondrial metabolites acylcarnitines: therapeutic potential and drug targets. Bioenerg Commun 2022.15. https://doi.org/10.26124/bec:2022-0015<br />
:from the O2k-Network »[[AT Innsbruck Oroboros]]« and »[[LV Riga Liepins E]]«<br />
|}<br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:BioblastAlert2024&diff=246368
Template:BioblastAlert2024
2024-03-06T14:23:51Z
<p>Tindle Lisa: </p>
<hr />
<div>__TOC__<br />
<br/><br />
=== Bioblast alert 2024(03) - Respiratory states: 2024-03-06 ===<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|Here is a system of terms and abbreviations for mitochondrial respiratory pathway and coupling control states.<br><br />
Although states and rates are distinguished by different symbols for coupling control states, such a distinction is not suggested for pathway control states and rates to avoid handing and overwhelming number of different symbols.<br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/Pathway_and_coupling_control_states MitoPedia: Pathway and coupling control states]'''«<br />
|}<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Do you know the difference between uncoupled, noncoupled and dyscoupled respiration? '''<br><br />
Noncoupled respiration is induced experimentally for evaluation of ET capacity, while uncoupling and dyscoupling are respectively caused by<br />
physiological and pathological conditions that exert an influence on proton leak and slip. <br><br />
- »'''[[Noncoupled_respiration|Noncoupled respiration]]'''«, »'''[[BEC_2020.1_doi10.26124bec2020-0001.v1|BEC 2020.01]]'''« <br><br />
|}<br />
<br />
:{|<br />
| width="110" align="center" | [[File:Gnaiger 2020 BEC MitoPathways.jpg|70px|link=https://www.bioenergetics-communications.org/index.php/bec/article/view/gnaiger_2020_mitopathways|Gnaiger 2020 BEC MitoPathways]]<br />
|'''What is ROUTINE respiration?'''<br><br />
ROUTINE respiration is the respiratory activity of living (non-permeabilized) cells in the physiological coupling state, which is controlled by cellular energy demand, energy turnover and the degree of coupling to phosphorylation. <br><br />
- »[https://www.bioenergetics-communications.org/index.php/bec/article/view/gnaiger_2020_mitopathways Gnaiger 2020 BEC MitoPathways - Chapter 2.4]« <br><br />
|}<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' What is the limitation of State 3 respiration compared to OXPHOS capacity? '''<br><br />
OXPHOS capacity is defined as the maximal respiratory capacity in the OXPHOS state in the presence of kinetically-saturating concentration of ADP, P<sub>i</sub>, fuel substrates and O<sub>2</sub>. However, State 3 as defined by Chance and Williams (1955) can lead to underestimation of OXPHOS capacity and overestimation of excess E-P capacity due to kinetic limitations of the phosphorylation system. <br><br />
- »'''[[OXPHOS capacity]]'''«, »'''[[excess E-P capacity]]'''« -<br><br />
-'''[[BEC_2020.1_doi10.26124bec2020-0001.v1|Gnaiger - MitoEAGLE Task Group (2020) Mitochondrial physiology - Table 3]]'''« <br />
|}<br />
----<br />
=== Bioblast alert 2024(02) - Bioenergetics Communications and EBEC2024: 2024-02-15 ===<br />
:{|<br />
| width="100" align="center" |[[File:BEC2024.1.jpg|right|150px|link=https://doi.org/10.26124/bec:2024-0001 |Gross 2024 BEC]]<br />
|'''The tale of two “best-friends,” proteins BID & MTCH2, pivotal regulators of the apoptosis and metabolism programs at the mitochondria.''' <br><br />
* Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001<br />
|}<br />
<br />
:{|<br />
| width="100" align="center" |[[File:EBEC2024 logo nobkg whiteshadow.png|100px|link=https://www.ebec2024.org |EBEC2024]]<br />
|'''EBEC2024 ''What is Life?'' Spotlights on Mito and Chlora:'''<br><br />
Cutting-edge research on mitochondria & chloroplasts, metabolism, and disease<br><br />
'''2024 August 26-31, Innsbruck, Austria'''<br><br />
- »[https://www.ebec2024.org/index.php/registration/ Registration and abstract submission open]« <br />
|}<br />
<br />
:{|<br />
| width="100" align="center" |[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''''Rewarded'' Open Access - compensating authors..'''<br><br />
Together with the MiP''society'', BEC is raising funds to reward the first 10 papers accepted for publication in BEC in 2024: 600 EUR to attend EBEC2024 and 2-year MiP''membership''.<br />
-»[https://whydonate.com/en/fundraising/BEC Support open access in science]«<br><br />
- »[https://www.bioenergetics-communications.org/index.php/bec/about/submissions Submit a manuscript]«<br />
|}<br />
----<br />
=== Bioblast alert 2024(01) - Fatty acid oxidation: 2024-02-08 ===<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Measuring fatty acid oxidation (FAO)-linked respiration requires a low concentration of malate '''<br><br />
In the absence of malate, accumulation of Acetyl-CoA inhibits FAO. <br><br />
- »'''[[Fatty acid oxidation pathway control state]]'''«, »'''[https://www.bioblast.at/index.php/Gnaiger_2020_BEC_MitoPathways Mitochondrial Pathways: Chapter 5]'''« <br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Cardoso Luiza]]« <br />
|}<br />
<br />
:{|<br />
| width="100" align="center" |[[File:MitoFit Preprints.png|100px|link=https://wiki.oroboros.at/images/0/00/Cecatto_2023_MitoFit.pdf |MitoFit pdf]]<br />
|'''"The capacity of FA oxidative phosphorylation (F-OXPHOS) with palmitoylcarnitine was up to 4 times higher than respiration with octanoylcarnitine. The optimal concentration of palmitoylcarnitine was 10 μM which corresponds to the total concentration of LC acylcarnitines in the brain."'''<br><br />
* Cecatto C, Cardoso LHD, Ozola M, Korzh S, Zvejniece L, Gukalova B, Doerrier C, Dambrova M, Gnaiger E, Makrecka-Kuka M, Liepinsh E (2023) Fatty acid β-oxidation in brain mitochondria: Insights from high-resolution respirometry in mouse, rat and Drosophila brain, ischemia and aging models. MitoFit Preprints 2023.10. https://doi.org/10.26124/mitofit:2023-0010<br />
:from the O2k-Network »[[AT Innsbruck Oroboros]]« and »[[LV Riga Liepins E]]«<br />
|}<br />
<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
| '''"... several graphical representations of the electron transfer system depict FADH2 in the mitochondrial matrix as a substrate to be oxidized by CII. This leads to the false conclusion that FADH2 from the β-oxidation cycle in fatty acid oxidation feeds electrons into CII. In reality, dehydrogenases of fatty acid oxidation channel electrons to the Q-junction but not through CII."'''<br><br />
* Gnaiger E (2024) Complex II ambiguities ― FADH2 in the electron transfer system. [[Gnaiger 2024 J Biol Chem|»Bioblast link«]]<br />
:from the O2k-Network »[[AT Innsbruck Oroboros]]« <br />
|}<br />
<br />
:{|<br />
| width="100" align="center" |[[File:BEC2022.15.jpg|right|150px|link=https://doi.org/10.26124/bec:2022-0015 |Dambrova 2022 BEC]]<br />
|'''"Clinically approved cardiovascular and diabetes drugs reduce LC acylcarnitine concentrations in vivo and it would be worth investigating whether these compounds could be repurposed."''' <br><br />
* Dambrova M, Cecatto C, Vilskersts R, Liepinsh E (2022) Mitochondrial metabolites acylcarnitines: therapeutic potential and drug targets. Bioenerg Commun 2022.15. https://doi.org/10.26124/bec:2022-0015<br />
:from the O2k-Network »[[AT Innsbruck Oroboros]]« and »[[LV Riga Liepins E]]«<br />
|}<br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=MOSBRI_Consensus_Meeting_2024_Rome_IT&diff=246364
MOSBRI Consensus Meeting 2024 Rome IT
2024-03-06T13:50:00Z
<p>Tindle Lisa: </p>
<hr />
<div>{{MitoGlobal header page name}}<br />
<br />
{{Publication<br />
|title='''Rome IT''', 2024 Apr 09. MOSBRI Consensus Meeting<br />
|info= [https://www.mosbri.eu/ Conference website]<br />
|authors= MOSBRI<br />
|year=2024-04-09<br />
|journal=MitoGlobal<br />
|abstract= tba<br />
}}<br />
<br />
== Venue ==<br />
:::: Sapienza University of Rome: Piazzale Aldo Moro, 5, 00185 Roma RM, Italy<br />
<br />
== Program ==<br />
:::: tba<br />
<br />
== Oroboros at MOSBRI Consensus Meeting ==<br />
:::: [[Gnaiger Erich|Erich Gnaiger]]: Quality-controlled high-resolution respirometry: bacterial and clinical applications<br />
<br />
<br />
{{Labeling<br />
|additional=2024, MitoGlobal, ORO, Next<br />
}}<br />
<br />
<br />
[[Image:MitoGlobal.jpg|right|80px|link=http://www.bioblast.at/index.php/MitoGlobal|MitoGlobal]] <br />
Listed under [[MitoGlobal Events]].</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Current_week_ecosystem_agenda&diff=246295
Template:Current week ecosystem agenda
2024-03-04T07:43:08Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:Science for Ukraine}}<br />
2024 Week 10<br />
<br />
* '''Mar-04 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test? '''<br><br />
Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.<br />
<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
* '''Mar-05 Tu''' <br />
----<br />
* '''Mar-06 We''' <br />
:{|<br />
| width="100" align="center" |[[File:BEC2024.1.jpg|right|150px|link=https://doi.org/10.26124/bec:2024-0001 |Gross 2024 BEC]]<br />
|'''The tale of two “best-friends,” proteins BID & MTCH2, pivotal regulators of the apoptosis and metabolism programs at the mitochondria.''' <br><br />
* Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001<br />
|}<br />
----<br />
* '''Mar-07 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Which medium can be used for the instrumental background test?'''<br><br />
When using dithionite, the instrumental background test should be performed in mitochondrial respiration medium MiR05, MiR05-Kit or MiR06; or alternatively, in a strong alkaline phosphate buffer (>100 mM; >pH 8), to avoid side reactions that might interfere with the test.<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background]]'''«<br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
----<br />
* '''Mar-08 Fr''' <br />
----<br />
<br />
'''<big>Next Week</big>'''<br />
2024 Week 11<br />
<br />
* '''Mar-11 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
----<br />
* '''Mar-12 Tu''' <br />
----<br />
* '''Mar-13 We''' <br />
:{|<br />
| width="100" align="center" |[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''''Rewarded'' Open Access - compensating authors..'''<br><br />
Together with the MiP''society'', BEC is raising funds to reward the first 10 papers accepted for publication in BEC in 2024: 600 EUR to attend EBEC2024 and 2-year MiP''membership''.<br />
-»[https://whydonate.com/en/fundraising/BEC Support open access in science]«<br><br />
- »[https://www.bioenergetics-communications.org/index.php/bec/about/submissions Submit a manuscript]«<br />
|}<br />
----<br />
* '''Mar-14 Th'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|} <br />
----<br />
* '''Mar-15 Fr''' <br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:O2k-PublicationAlert2024&diff=246294
Template:O2k-PublicationAlert2024
2024-03-04T07:43:03Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:OROBOROS Slogan}}<br />
::::<big>» Listed in '''[[OROBOROS_INSTRUMENTS|Oroboros Ecosystem Agenda ]]'''</big><br />
__TOC__<br />
== Mar 2024 ==<br />
* '''Mar-06 We''' <br />
:{|<br />
| width="100" align="center" |[[File:BEC2024.1.jpg|right|150px|link=https://doi.org/10.26124/bec:2024-0001 |Gross 2024 BEC]]<br />
|'''The tale of two “best-friends,” proteins BID & MTCH2, pivotal regulators of the apoptosis and metabolism programs at the mitochondria.''' <br><br />
* Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001<br />
|}<br />
----<br />
== Feb 2024 ==<br />
* '''Feb-29 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Bed rest results in a decrease in skeletal muscle mitochondrial respiratory capacity, mainly as a result of an observed decrease in mitochondrial content"''' <br><br />
* Noone J, Damiot A, Kenny H, Chery I, Zahariev A, Normand S, Crampes F, de Glisezinski I, Rochfort KD, Laurens C, Bareille MP, Simon C, Bergouignan A, Blanc S, O'Gorman DJ (2023) The impact of 60 days of -6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics. [[Noone 2023 J Physiol|»Bioblast link«]]<br />
:from the O2k-Networks »[[US FL Orlando Goodpaster BH]]« , »[[FR Strasbourg Blanc S]]« , »[[IE Dublin O Gorman D]]«<br />
|}<br />
----<br />
* '''Feb-15 Th''' - International Childhood Cancer Day<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Deleterious mtDNA mutations contribute significantly to the tumorigenesis of pediatric cancers"''' <br><br />
* Triska P, Kaneva K, Merkurjev D, Sohail N, Falk MJ, Triche TJ Jr, Biegel JA, Gai X (2019) Landscape of germline and somatic mitochondrial DNA mutations in pediatric malignancies. [[Triska 2019 Cancer Res|»Bioblast link«]]<br />
:from the O2k-Network »[[US_PA_Philadelphia_Falk_MJ]]«<br />
|}<br />
----<br />
* '''Feb-05 Mo'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"We demonstrated deficient platelet mitochondrial respiratory chain functions, oxidative phosphorylation (OXPHOS), and electron transfer (ET) capacity with complex I (CI)-linked substrates, and reduced [...] endogenous platelet coenzyme Q10 (CoQ10) concentration in UC [urothelial carcinoma] patients."''' <br><br />
* Palacka P, Gvozdjáková A, Rausová Z, Kucharská J, Slopovský J, Obertová J, Furka D, Furka S, Singh KK, Sumbalová Z (2021) Platelet mitochondrial bioenergetics reprogramming in patients with urothelial carcinoma. [[Palacka 2021 Int J Mol Sci|»Bioblast link«]]<br />
:from the O2k-Network »[[SK Bratislava Sumbalova Z]]«<br />
|}<br />
----<br />
== Jan 2024 ==<br />
<br />
* '''Jan-04 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Oxygen Consumption Rate (OCR) measurements of fresh and cryopreserved placental specimens are comparable whereas snap frozen procedure impairs mitochondrial activity"''' <br><br />
* Giovarelli M, Serati A, Zecchini S, Guelfi F, Clementi E, Mandò C (2023) Cryopreserved placental biopsies maintain mitochondrial activity for high-resolution respirometry. [[Giovarelli 2023 Mol Med|»Bioblast link«]]<br />
:from the O2k-Network »[[IT Milan Clementi E]]«<br />
|}<br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:O2k-OpenSupportAlert2024&diff=246293
Template:O2k-OpenSupportAlert2024
2024-03-04T07:42:27Z
<p>Tindle Lisa: </p>
<hr />
<div>:::::: <big>''Currently Answered Questions from the »[[OROBOROS_INSTRUMENTS |Oroboros Ecosystem Agenda]]«<br />
</big><br />
<br />
__TOC__<br />
== Mar 2024 ==<br />
* '''Mar-07 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Which medium can be used for the instrumental background test?'''<br><br />
When using dithionite, the instrumental background test should be performed in mitochondrial respiration medium MiR05, MiR05-Kit or MiR06; or alternatively, in a strong alkaline phosphate buffer (>100 mM; >pH 8), to avoid side reactions that might interfere with the test.<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background]]'''«<br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
----<br />
<br />
* '''Mar-04 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test? '''<br><br />
Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.<br />
<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
== Feb 2024 ==<br />
* '''Feb-22 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''What to do if the glass of the O2k-chamber starts to become opaque?'''<br><br />
"Turbidity on the glass wall may be caused by precipitated protein. Remove the chambers from the O2k and with the O2k-stirrers removed, immerse in a beaker filled with HCl (10 M) overnight under a hood." <br><br />
-»'''[[MiPNet19.03_O2k-cleaning_and_ISS]]'''«<br><br />
- communicated by »[[Cardoso Luiza]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Feb-08 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Can I use the same stock solutions for all reagents for different O2k-chamber volumes?'''<br><br />
"For some reagents, the concentration of the stock solution differs between the 2.0-mL and the 0.5-mL chamber (O2k-sV-Module) to facilitate a precise volume titration."<br><br />
-»'''[[MiPNet09.12 O2k-Titrations]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
== Jan 2024 ==<br />
* '''Jan-25 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''How do I view and change the settings of a measurement/file in DatLab 8?'''<br><br />
"O2k control (active) will always show the settings of the active recording [and allow changes], while O2k info (view) will show the settings of the recorded selected file."<br><br />
<br />
-»'''[[MiPNet28.07 NextGen-O2k Series XB manual]]'''«; »'''[[MiPNet28.08 Oroboros O2k Series J manual]]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
----<br />
* '''Jan-11 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''What are special features of the new SmartPOS (O2k-Series J and NextGen-O2k-Series XB)?'''<br><br />
- "The electrical connections of the SmartPOS are protected thus there is no need to clean them."<br> <br />
- "The serial number of the SmartPOS is automatically recognized by the DatLab 8 software."<br><br />
<br />
»'''[[MiPNet28.10 SmartPOS-service]]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
<br />
* '''Jan-08 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Do you need to export DatLab traces for your publication? '''<br><br />
Save your graph as an editable picture using "Copy to clipboard" in DatLab 7.4 (.wmf) or "Save" in DatLab 8 (.svg).<br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/Copy_to_clipboard Copy to clipboard in DatLab 7]'''«, »'''[https://www.oroboros.at/index.php/product/datlab/ Download DatLab 8]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Next_oroboros_ecosystem_agenda&diff=246292
Template:Next oroboros ecosystem agenda
2024-03-04T07:41:18Z
<p>Tindle Lisa: </p>
<hr />
<div> 2024 Week 12<br />
<br />
* '''Mar-18 Mo'''<br />
::::: <big> '''[[EU-METAHEART MC2 Meeting 2024 Antalya TR]]'''</big> Mar 18-21<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' What if ''Alert: Error in titrations!'' appears in your O2 analysis template file? '''<br><br />
The O2 analysis template recognizes discrepancies between the protocol selected in the first tab and the imported marks. Check the titration sequence and mark names against the protocol copied from the DLD file.<br><br />
- »'''[[MiPNet24.06 Oxygen flux analysis - DatLab 7.4|O<sub>2</sub> flux analysis]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
<br />
----<br />
* '''Mar-19 Tu''' <br />
::::: <big> '''[[EU-METAHEART MC2 Meeting 2024 Antalya TR]]'''</big> Mar 18-21<br />
----<br />
* '''Mar-20 We''' <br />
::::: <big> '''[[EU-METAHEART MC2 Meeting 2024 Antalya TR]]'''</big> Mar 18-21<br />
----<br />
* '''Mar-21 Th''' <br />
::::: <big> '''[[EU-METAHEART MC2 Meeting 2024 Antalya TR]]'''</big> Mar 18-21<br />
----<br />
* '''Mar-22 Fr'''<br />
<br />
2024 Week 13<br />
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* '''Mar-25 Mo'''<br />
----<br />
* '''Mar-26 Tu''' <br />
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* '''Mar-27 We''' <br />
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* '''Mar-28 Th''' <br />
----<br />
* '''Mar-29 Fr'''<br />
<br />
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2024 Week 14<br />
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* '''Apr-01 Mo''' <br />
----<br />
* '''Apr-02 Tu''' <br />
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* '''Apr-03 We''' <br />
----<br />
* '''Apr-04 Th''' <br />
----<br />
* '''Apr-05 Fr'''<br />
<br />
2024 Week 15<br />
<br />
* '''Apr-08 Mo'''<br />
----<br />
* '''Apr-09 Tu''' <br />
::::: <big> '''[[MOSBRI Consensus Meeting 2024 Rome IT]]'''</big> <br />
----<br />
* '''Apr-10 We''' <br />
----<br />
* '''Apr-11 Th''' <br />
----<br />
* '''Apr-12 Fr'''<br />
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2024 Week 16<br />
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* '''Apr-15 Mo''' <br />
----<br />
* '''Apr-16 Tu''' <br />
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* '''Apr-17 We''' <br />
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* '''Apr-18 Th''' <br />
----<br />
* '''Apr-19 Fr'''<br />
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2024 Week 17<br />
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* '''Apr-22 Mo'''<br />
----<br />
* '''Apr-23 Tu''' <br />
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* '''Apr-24 We''' <br />
----<br />
* '''Apr-25 Th''' <br />
----<br />
* '''Apr-26 Fr'''<br />
<br />
2024 Week 18<br />
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* '''Apr-29 Mo'''<br />
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* '''Apr-30 Tu''' <br />
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* '''May-01 We''' <br />
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* '''May-02 Th''' <br />
----<br />
* '''May-03 Fr'''<br />
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2024 Week 19<br />
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* '''May-06 Mo'''<br />
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* '''May-07 Tu''' <br />
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* '''May-08 We''' <br />
----<br />
* '''May-09 Th''' <br />
----<br />
* '''May-10 Fr'''<br />
<br />
2024 Week 20<br />
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* '''May-13 Mo'''<br />
----<br />
* '''May-14 Tu''' <br />
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* '''May-15 We''' <br />
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* '''May-16 Th''' <br />
----<br />
* '''May-17 Fr'''<br />
<br />
2024 Week 21<br />
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* '''May-20 Mo''' <br />
----<br />
* ''May-21 Tu''' <br />
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* '''May-22 We''' <br />
----<br />
* '''May-23 Th''' <br />
----<br />
* '''May-24 Fr'''<br />
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2024 Week 22<br />
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* '''May-27 Mo'''<br />
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* '''May-28 Tu''' <br />
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* '''May-29 We''' <br />
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* '''May-30 Th''' <br />
----<br />
* '''May-31 Fr'''<br />
<br />
2024 Week 23<br />
<br />
* '''Jun-03 Mo'''<br />
----<br />
* '''Jun-04 Tu''' <br />
----<br />
* '''Jun-05 We''' <br />
----<br />
* '''Jun-06 Th''' <br />
----<br />
* '''Jun-07 Fr'''<br />
<br />
2024 Week 24<br />
<br />
* '''Jun-10 Mo'''<br />
----<br />
* '''Jun-11 Tu''' <br />
----<br />
* '''Jun-12 We''' <br />
----<br />
* '''Jun-13 Th''' <br />
----<br />
* '''Jun-14 Fr'''<br />
<br />
2024 Week 25<br />
<br />
* '''Jun-17 Mo'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
<br />
----<br />
* '''Jun-18 Tu''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-19 We''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-20 Th''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-21 Fr'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
<br />
2024 Week 26<br />
<br />
* '''Jun-24 Mo'''<br />
----<br />
* '''Jun-25 Tu''' <br />
----<br />
* '''Jun-26 We''' <br />
----<br />
* '''Jun-27 Th''' <br />
----<br />
* '''Jun-28 Fr'''<br />
<br />
<br />
2024 Week 27<br />
<br />
* '''Jul-01 Mo'''<br />
----<br />
* '''Jul-02 Tu''' <br />
----<br />
* '''Jul-03 We''' <br />
----<br />
* '''Jul-04 Th''' <br />
----<br />
* '''Jul-05 Fr'''<br />
<br />
2024 Week 28<br />
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* '''Jul-08 Mo'''<br />
----<br />
* '''Jul-09 Tu''' <br />
----<br />
* '''Jul-10 We''' <br />
----<br />
* '''Jul-11 Th''' <br />
----<br />
* '''Jul-12 Fr'''<br />
<br />
2024 Week 29<br />
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* '''Jul-15 Mo'''<br />
----<br />
* '''Jul-16 Tu''' <br />
----<br />
* '''Jul-17 We''' <br />
----<br />
* '''Jul-18 Th''' <br />
----<br />
* '''Jul-19 Fr'''<br />
<br />
2024 Week 30<br />
<br />
* '''Jul-22 Mo'''<br />
----<br />
* '''Jul-23 Tu''' <br />
----<br />
* '''Jul-24 We''' <br />
----<br />
* '''Jul-25 Th''' <br />
----<br />
* '''Jul-26 Fr'''<br />
<br />
2024 Week 31<br />
<br />
* '''Jul-29 Mo'''<br />
----<br />
* '''Jul-30 Tu''' <br />
----<br />
* '''Jul-31 We''' <br />
----<br />
* '''Aug-01 Th''' <br />
----<br />
* '''Aug-02 Fr'''<br />
<br />
2024 Week 32<br />
<br />
* '''Aug-05 Mo'''<br />
----<br />
* '''Aug-06 Tu''' <br />
----<br />
* '''Aug-07 We''' <br />
----<br />
* '''Aug-08 Th''' <br />
----<br />
* '''Aug-09 Fr'''<br />
<br />
2024 Week 33<br />
<br />
* '''Aug-12 Mo'''<br />
----<br />
* '''Aug-13 Tu''' <br />
----<br />
* '''Aug-14 We''' <br />
----<br />
* '''Aug-15 Th''' <br />
----<br />
* '''Aug-16 Fr'''<br />
<br />
2024 Week 34<br />
<br />
* '''Aug-19 Mo'''<br />
----<br />
* '''Aug-20 Tu''' <br />
----<br />
* '''Aug-21 We''' <br />
----<br />
* '''Aug-22 Th''' <br />
----<br />
* '''Aug-23 Fr'''<br />
<br />
2024 Week 35<br />
<br />
* '''Aug-26 Mo'''<br />
----<br />
* '''Aug-27 Tu''' <br />
----<br />
* '''Aug-28 We''' <br />
----<br />
* '''Aug-29 Th''' <br />
----<br />
* '''Aug-30 Fr'''<br />
<br />
2024 Week 36<br />
<br />
* '''Sep-02 Mo'''<br />
----<br />
* '''Sep-03 Tu''' <br />
----<br />
* '''Sep-04 We''' <br />
----<br />
* '''Sep-05 Th''' <br />
----<br />
* '''Sep-06 Fr'''<br />
<br />
2024 Week 37<br />
<br />
* '''Sep-09 Mo'''<br />
----<br />
* '''Sep-10 Tu''' <br />
----<br />
* '''Sep-11 We''' <br />
----<br />
* '''Sep-12 Th''' <br />
----<br />
* '''Sep-13 Fr'''<br />
<br />
2024 Week 38<br />
<br />
* '''Sep-16 Mo'''<br />
----<br />
* '''Sep-17 Tu''' <br />
----<br />
* '''Sep-18 We''' <br />
----<br />
* '''Sep-19 Th''' <br />
----<br />
* '''Sep-20 Fr'''<br />
<br />
2024 Week 39<br />
<br />
* '''Sep-22 Su'''<br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
* '''Sep-23 Mo'''<br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-24 Tu''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-25 We''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-26 Th''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-27 Fr'''<br />
<br />
<br />
2024 Week 40<br />
<br />
* '''Sep-30 Mo'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-01 Tu''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-02 We''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-03 Th''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-04 Fr'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
<br />
2024 Week 41<br />
<br />
* '''Okt-07 Mo'''<br />
----<br />
* '''Okt-08 Tu''' <br />
----<br />
* '''Okt-09 We''' <br />
----<br />
* '''Okt-10 Th''' <br />
----<br />
* '''Okt-11 Fr'''<br />
<br />
2024 Week 42<br />
<br />
* '''Okt-14 Mo'''<br />
----<br />
* '''Okt-15 Tu''' <br />
----<br />
* '''Okt-16 We''' <br />
----<br />
* '''Okt-17 Th''' <br />
----<br />
* '''Okt-18 Fr'''<br />
<br />
2024 Week 43<br />
<br />
* '''Okt-21 Mo'''<br />
----<br />
* '''Okt-22 Tu''' <br />
----<br />
* '''Okt-23 We''' <br />
----<br />
* '''Okt-24 Th''' <br />
----<br />
* '''Okt-25 Fr'''<br />
::::: <big> '''[[14th Mitochondrial Disease Conference 2024 Padova IT]]'''</big> 2024 Oct 25-27<br />
<br />
2024 Week 44<br />
<br />
* '''Okt-28 Mo'''<br />
----<br />
* '''Okt-29 Tu''' <br />
----<br />
* '''Okt-30 We''' <br />
----<br />
* '''Okt-31 Th''' <br />
----<br />
* '''Nov-01 Fr''' <br />
<br />
2024 Week 45<br />
<br />
* '''Nov-04 Mo'''<br />
----<br />
* '''Nov-05 Tu''' <br />
----<br />
* '''Nov-06 We''' <br />
----<br />
* '''Nov-07 Th''' <br />
----<br />
* '''Nov-08 Fr'''<br />
<br />
2024 Week 46<br />
<br />
* '''Nov-11 Mo'''<br />
----<br />
* '''Nov-12 Tu''' <br />
----<br />
* '''Nov-13 We''' <br />
----<br />
* '''Nov-14 Th''' <br />
----<br />
* '''Nov-15 Fr'''<br />
<br />
<br />
2024 Week 47<br />
<br />
* '''Nov-18 Mo'''<br />
----<br />
* '''Nov-19 Tu''' <br />
----<br />
* '''Nov-20 We''' <br />
----<br />
* '''Nov-21 Th''' <br />
----<br />
* '''Nov-22 Fr'''<br />
<br />
2024 Week 48<br />
<br />
* '''Nov-25 Mo'''<br />
----<br />
* '''Nov-26 Tu''' <br />
----<br />
* '''Nov-27 We''' <br />
----<br />
* '''Nov-28 Th''' <br />
----<br />
* '''Nov-29 Fr'''<br />
<br />
2024 Week 49<br />
<br />
* '''Dez-02 Mo'''<br />
----<br />
* '''Dez-03 Tu''' <br />
----<br />
* '''Dez-04 We''' <br />
----<br />
* '''Dez-05 Th''' <br />
----<br />
* '''Dez-06 Fr'''<br />
<br />
2024 Week 50<br />
<br />
* '''Dez-09 Mo'''<br />
----<br />
* '''Dez-10 Tu''' <br />
----<br />
* '''Dez-11 We''' <br />
----<br />
* '''Dez-12 Th''' <br />
----<br />
* '''Dez-13 Fr'''<br />
<br />
2024 Week 51<br />
<br />
* '''Dez-16 Mo'''<br />
----<br />
* '''Dez-17 Tu''' <br />
----<br />
* '''Dez-18 We''' <br />
----<br />
* '''Dez-19 Th''' <br />
----<br />
* '''Dez-20 Fr'''<br />
<br />
2024 Week 52<br />
<br />
* '''Dez-23 Mo'''<br />
----<br />
* '''Dez-24 Tu''' <br />
----<br />
* '''Dez-25 We''' <br />
----<br />
* '''Dez-26 Th''' <br />
----<br />
* '''Dez-27 Fr'''</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Oroboros_Ecosystem_Agenda_2024_Archive&diff=246291
Oroboros Ecosystem Agenda 2024 Archive
2024-03-04T07:41:14Z
<p>Tindle Lisa: </p>
<hr />
<div>{{OROBOROS header page name}}<br />
<br />
{{Template:OROBOROS Slogan}}<br />
<br />
::::<big>» [[OROBOROS INSTRUMENTS|Current Oroboros Ecosystem Agenda ]]</big><br />
<br />
__TOC__<br />
<br />
== Last week ==<br />
2024 Week 09<br />
<br />
* '''Feb-26 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' ATP synthase = phosphorylation system? '''<br><br />
No, the phosphorylation system consists of adenine nucleotide translocase, phosphate carrier, and ATP synthase, which carry out the steps in the phosphorylation pathway. <br><br />
- »'''[[Phosphorylation pathway]]'''«, »'''[https://www.bioblast.at/index.php/Gnaiger_2020_BEC_MitoPathways Mitochondrial Pathways: Chapter 2.2]'''« <br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Feb-27 Tu''' <br />
----<br />
* '''Feb-28 We''' <br />
----<br />
* '''Feb-29 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Bed rest results in a decrease in skeletal muscle mitochondrial respiratory capacity, mainly as a result of an observed decrease in mitochondrial content"''' <br><br />
* Noone J, Damiot A, Kenny H, Chery I, Zahariev A, Normand S, Crampes F, de Glisezinski I, Rochfort KD, Laurens C, Bareille MP, Simon C, Bergouignan A, Blanc S, O'Gorman DJ (2023) The impact of 60 days of -6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics. [[Noone 2023 J Physiol|»Bioblast link«]]<br />
:from the O2k-Networks »[[US FL Orlando Goodpaster BH]]« , »[[FR Strasbourg Blanc S]]« , »[[IE Dublin O Gorman D]]«<br />
|}<br />
----<br />
* '''Mar-01 Fr''' <br />
----<br />
<br />
<br />
== Feb 2024 ==<br />
2024 Week 06<br />
<br />
* '''Feb-05 Mo'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"We demonstrated deficient platelet mitochondrial respiratory chain functions, oxidative phosphorylation (OXPHOS), and electron transfer (ET) capacity with complex I (CI)-linked substrates, and reduced [...] endogenous platelet coenzyme Q10 (CoQ10) concentration in UC [urothelial carcinoma] patients."''' <br><br />
* Palacka P, Gvozdjáková A, Rausová Z, Kucharská J, Slopovský J, Obertová J, Furka D, Furka S, Singh KK, Sumbalová Z (2021) Platelet mitochondrial bioenergetics reprogramming in patients with urothelial carcinoma. [[Palacka 2021 Int J Mol Sci|»Bioblast link«]]<br />
:from the O2k-Network »[[SK Bratislava Sumbalova Z]]«<br />
|}<br />
----<br />
* '''Feb-06 Tu''' <br />
----<br />
* '''Feb-07 We''' <br />
----<br />
* '''Feb-08 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Can I use the same stock solutions for all reagents for different O2k-chamber volumes?'''<br><br />
For some reagents, the concentration of the stock solution differs between the 2.0-mL and the 0.5-mL chamber (O2k-sV-Module) to facilitate a precise volume titration.<br><br />
-»'''[[MiPNet09.12 O2k-Titrations]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Feb-09 Fr''' <br />
----<br />
* '''Feb-10 Sa'''<br />
[[File:Year of the Dragon.jpg|400px]] [[File:ChineseNewYear2024 Taiwan.jpg|400px]]<br><br />
<br />
2024 Week 07<br />
<br />
* '''Feb-12 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' What is the O<sub>2</sub> solubility factor of the medium (''F''<sub>M</sub>) and why is it important? '''<br><br />
''F''<sub>M</sub> expresses the effect of the salt concentration on oxygen solubility relative to pure water, and varies depending on the temperature and composition of the medium. The correct ''F''<sub>M</sub> needs to be entered in DatLab when performing an air calibration. <br><br />
- »'''[[Oxygen solubility factor]]'''« , »'''[[Oxygen_calibration_-_DatLab#Air_calibration_in_DatLab|Air calibration in DatLab]]'''« <br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Feb-13 Tu''' <br />
----<br />
* '''Feb-14 We''' <br />
----<br />
* '''Feb-15 Th''' - International Childhood Cancer Day<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Deleterious mtDNA mutations contribute significantly to the tumorigenesis of pediatric cancers"''' <br><br />
* Triska P, Kaneva K, Merkurjev D, Sohail N, Falk MJ, Triche TJ Jr, Biegel JA, Gai X (2019) Landscape of germline and somatic mitochondrial DNA mutations in pediatric malignancies. [[Triska 2019 Cancer Res|»Bioblast link«]]<br />
:from the O2k-Network »[[US_PA_Philadelphia_Falk_MJ]]«<br />
|}<br />
----<br />
* '''Feb-16 Fr''' <br />
----<br />
2024 Week 08<br />
<br />
* '''Feb-19 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“We just published this paper on [https://academic.oup.com/biomedgerontology/advance-article/doi/10.1093/gerona/glad283/7502466 SOMMA], possibly one of the largest aging studies involving permeabilized muscle energetics. Couldn't have done it without the training your teams provided.”'''''<br><br />
'''[[Kramer Philip A]]''' from the O2k-Network Lab »[[US NC Winston-Salem Kramer PA]]«<br><br />
- »'''[https://wiki.oroboros.at/index.php/O2k-Feedback#More_O2k-Feedback| O2k-Feedback]'''«<br><br />
|}<br />
----<br />
* '''Feb-20 Tu''' <br />
----<br />
* '''Feb-21 We''' <br />
----<br />
* '''Feb-22 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''What to do if the glass of the O2k-chamber starts to become opaque?'''<br><br />
"Turbidity on the glass wall may be caused by precipitated protein. Remove the chambers from the O2k and with the O2k-stirrers removed, immerse in a beaker filled with HCl (10 M) overnight under a hood." <br><br />
-»'''[[MiPNet19.03_O2k-cleaning_and_ISS]]'''«<br><br />
- communicated by »[[Cardoso Luiza]]« and »[[Leo Elettra]]«<br />
|}<br />
----<br />
* '''Feb-23 Fr''' <br />
----<br />
<br />
== Jan 2024 ==<br />
2024 Week 01<br />
* '''Jan-01 Mo'''<br />
----<br />
* '''Jan-02 Tu'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' New year, new state? What is REN state? '''<br><br />
REN state is now distinguished from ROX state: REN is measured in mitochondrial preparations without addition of substrates, whereas ROX is due to oxidative side reactions remaining after inhibition of the electron transfer pathway. <br> <br />
- »'''[[Residual endogenous substrates|REN]]'''«, »'''[[Residual oxygen consumption|ROX]]'''« <br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]« <br />
|} <br />
----<br />
* '''Jan-03 We''' <br />
----<br />
* '''Jan-04 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Oxygen Consumption Rate (OCR) measurements of fresh and cryopreserved placental specimens are comparable whereas snap frozen procedure impairs mitochondrial activity"''' <br><br />
* Giovarelli M, Serati A, Zecchini S, Guelfi F, Clementi E, Mandò C (2023) Cryopreserved placental biopsies maintain mitochondrial activity for high-resolution respirometry. [[Giovarelli 2023 Mol Med|»Bioblast link«]]<br />
:from the O2k-Network »[[IT Milan Clementi E]]«<br />
|}<br />
----<br />
* '''Jan-05 Fr'''<br />
-----<br />
2024 Week 02<br />
<br />
* '''Jan-08 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Do you need to export DatLab traces for your publication? '''<br><br />
Save your graph as an editable picture using "Copy to clipboard" in DatLab 7.4 (.wmf) or "Save" in DatLab 8 (.svg).<br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/Copy_to_clipboard Copy to clipboard in DatLab 7]'''«, »'''[https://www.oroboros.at/index.php/product/datlab/ Download DatLab 8]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
----<br />
* '''Jan-09 Tu''' <br />
----<br />
* '''Jan-10 We'''<br />
:::: '''»[[AICBC 2024 Navi Mumbai IN]]«''' Jan 10-12<br />
----<br />
* '''Jan-11 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''What are special features of the new SmartPOS (O2k-Series J and NextGen-O2k-Series XB)?'''<br><br />
- "The electrical connections of the SmartPOS are protected thus there is no need to clean them."<br> <br />
- "The serial number of the SmartPOS is automatically recognized by the DatLab 8 software."<br><br />
<br />
»'''[[MiPNet28.10 SmartPOS-service]]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
* '''Jan-12 Fr'''<br />
----<br />
2024 Week 03<br />
<br />
* '''Jan-15 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why electron transfer pathway and not electron transfer chain? '''<br><br />
The term “chain” suggests a linear sequence, however, the convergence of electron flow at the Q-junction indicates a higher degree of complexity, making “pathway” a more fitting descriptor. <br><br />
- »'''[[Electron transfer pathway]]'''«, »'''[[Gnaiger 2020 BEC MitoPathways]]'''« <br><br />
- communicated by »[[Leo Elettra]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Jan-16 Tu''' <br />
----<br />
* '''Jan-17 We''' <br />
----<br />
* '''Jan-18 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''The study on rats by Jedlička et al indicates that "...the concept of general pattern of age-dependent decline in mitochondrial oxygen consumption across different organs and tissues could be misleading."''' <br><br />
*Jedlička J, Tůma Z, Razak K, Kunc R, Kala A, Proskauer Pena S, Lerchner T, Ježek K, Kuncová J (2022) Impact of aging on mitochondrial respiration in various organs. [[Jedlicka_2022a_Physiol_Res|»Bioblast link«]]<br />
:from the O2k-Network »[[CZ_Pilsen_Kuncova_J]]«<br />
|}<br />
----<br />
* '''Jan-19 Fr'''<br />
----<br />
2024 Week 04<br />
<br />
* '''Jan-22 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“We are truly glad to have your continued support and partnership.”'''''<br><br />
'''[[Lu Amelia]]''' from the O2k-Network Lab »[[TW Taoyuan Sunpoint]]«<br><br />
- »'''[https://wiki.oroboros.at/index.php/O2k-Feedback#More_O2k-Feedback| O2k-Feedback]'''«<br><br />
|}<br />
----<br />
* '''Jan-23 Tu''' <br />
----<br />
* '''Jan-24 We''' <br />
----<br />
* '''Jan-25 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''How do I view and change the settings of a measurement/file in DatLab 8?'''<br><br />
"O2k control (active) will always show the settings of the active recording [and allow changes], while O2k info (view) will show the settings of the recorded selected file."<br><br />
<br />
-»'''[[MiPNet28.07 NextGen-O2k Series XB manual]]'''«; »'''[[MiPNet28.08 Oroboros O2k Series J manual]]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
----<br />
* '''Jan-26 Fr''' <br />
----<br />
2024 Week 05<br />
* '''Jan-29 Mo'''<br />
:::: '''»[[E-mit Winter School 2024 Brixen IT]]«''' Jan 28 - Feb 02<br />
----<br />
* '''Jan-30 Tu'''<br />
:::: '''16:30 [[Gnaiger Erich|Erich Gnaiger]] presenting at [[E-mit Winter School 2024 Brixen IT]]''' - ''Coupling control and pathway control in mitochondrial high-resolution respirometry''<br />
----<br />
* '''Jan-31 We''' <br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Can the S-pathway O<sub><small>2</small></sub> flux be derived by subtracting N-pathway O<sub><small>2</small></sub> flux from NS-pathway O<sub><small>2</small></sub> flux?'''<br><br />
No, the sum of the O<sub><small>2</small></sub> fluxes measured in the presence of NADH-linked substrates alone and succinate as the single substrate is typically higher than using a combination of all these substrates. This effect is described as incomplete additivity: <br><br />
- »'''[[Additive effect of convergent electron flow]]'''« <br><br />
- communicated by »[[Cardoso Luiza]]« and »[[Grings Mateus]]« <br />
|}<br />
----<br />
* '''Feb-01 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“Doing the entire hands-on module from start to finish was the best for really “cementing” theory and hands-on application together.”'''''<br><br />
[[Cosgrove Richard]] from Eli Lilly Research Labs, on what he liked best on [[IOC162]]<br><br />
- »'''[[O2k-Feedback]]'''«<br><br />
|}<br />
----<br />
* '''Feb-02 Fr''' <br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Current_week_ecosystem_agenda&diff=246290
Template:Current week ecosystem agenda
2024-03-04T07:41:09Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:Science for Ukraine}}<br />
2024 Week 10<br />
<br />
* '''Mar-04 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test? '''<br><br />
Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.<br />
<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
* '''Mar-05 Tu''' <br />
----<br />
* '''Mar-06 We''' <br />
:{|<br />
| width="100" align="center" |[[File:BEC2024.1.jpg|right|150px|link=https://doi.org/10.26124/bec:2024-0001 |Gross 2024 BEC]]<br />
|'''The tale of two “best-friends,” proteins BID & MTCH2, pivotal regulators of the apoptosis and metabolism programs at the mitochondria.''' <br><br />
* Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001<br />
|}<br />
----<br />
* '''Mar-07 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Which medium can be used for the instrumental background test?'''<br><br />
When using dithionite, the instrumental background test should be performed in mitochondrial respiration medium MiR05, MiR05-Kit or MiR06; or alternatively, in a strong alkaline phosphate buffer (>100 mM; >pH 8), to avoid side reactions that might interfere with the test.<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background]]'''«<br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
<br />
----<br />
* '''Mar-08 Fr''' <br />
----<br />
<br />
'''<big>Next Week</big>'''<br />
2024 Week 11<br />
<br />
* '''Mar-11 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
----<br />
* '''Mar-12 Tu''' <br />
----<br />
* '''Mar-13 We''' <br />
:{|<br />
| width="100" align="center" |[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''''Rewarded'' Open Access - compensating authors..'''<br><br />
Together with the MiP''society'', BEC is raising funds to reward the first 10 papers accepted for publication in BEC in 2024: 600 EUR to attend EBEC2024 and 2-year MiP''membership''.<br />
-»[https://whydonate.com/en/fundraising/BEC Support open access in science]«<br><br />
- »[https://www.bioenergetics-communications.org/index.php/bec/about/submissions Submit a manuscript]«<br />
|}<br />
----<br />
* '''Mar-14 Th'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|} <br />
----<br />
* '''Mar-15 Fr''' <br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Next_oroboros_ecosystem_agenda&diff=246255
Template:Next oroboros ecosystem agenda
2024-02-28T15:41:07Z
<p>Tindle Lisa: </p>
<hr />
<div> 2024 Week 11<br />
<br />
* '''Mar-11 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
----<br />
* '''Mar-12 Tu''' <br />
----<br />
* '''Mar-13 We''' <br />
:{|<br />
| width="100" align="center" |[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''''Rewarded'' Open Access - compensating authors..'''<br><br />
Together with the MiP''society'', BEC is raising funds to reward the first 10 papers accepted for publication in BEC in 2024: 600 EUR to attend EBEC2024 and 2-year MiP''membership''.<br />
-»[https://whydonate.com/en/fundraising/BEC Support open access in science]«<br><br />
- »[https://www.bioenergetics-communications.org/index.php/bec/about/submissions Submit a manuscript]«<br />
|}<br />
----<br />
* '''Mar-14 Th'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|} <br />
----<br />
* '''Mar-15 Fr''' <br />
<br />
2024 Week 12<br />
<br />
* '''Mar-18 Mo'''<br />
::::: <big> '''[[EU-METAHEART MC2 Meeting 2024 Antalya TR]]'''</big> Mar 18-21<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' What if ''Alert: Error in titrations!'' appears in your O2 analysis template file? '''<br><br />
The O2 analysis template recognizes discrepancies between the protocol selected in the first tab and the imported marks. Check the titration sequence and mark names against the protocol copied from the DLD file.<br><br />
- »'''[[MiPNet24.06 Oxygen flux analysis - DatLab 7.4|O<sub>2</sub> flux analysis]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
<br />
----<br />
* '''Mar-19 Tu''' <br />
::::: <big> '''[[EU-METAHEART MC2 Meeting 2024 Antalya TR]]'''</big> Mar 18-21<br />
----<br />
* '''Mar-20 We''' <br />
::::: <big> '''[[EU-METAHEART MC2 Meeting 2024 Antalya TR]]'''</big> Mar 18-21<br />
----<br />
* '''Mar-21 Th''' <br />
::::: <big> '''[[EU-METAHEART MC2 Meeting 2024 Antalya TR]]'''</big> Mar 18-21<br />
----<br />
* '''Mar-22 Fr'''<br />
<br />
2024 Week 13<br />
<br />
* '''Mar-25 Mo'''<br />
----<br />
* '''Mar-26 Tu''' <br />
----<br />
* '''Mar-27 We''' <br />
----<br />
* '''Mar-28 Th''' <br />
----<br />
* '''Mar-29 Fr'''<br />
<br />
<br />
2024 Week 14<br />
<br />
* '''Apr-01 Mo''' <br />
----<br />
* '''Apr-02 Tu''' <br />
----<br />
* '''Apr-03 We''' <br />
----<br />
* '''Apr-04 Th''' <br />
----<br />
* '''Apr-05 Fr'''<br />
<br />
2024 Week 15<br />
<br />
* '''Apr-08 Mo'''<br />
----<br />
* '''Apr-09 Tu''' <br />
::::: <big> '''[[MOSBRI Consensus Meeting 2024 Rome IT]]'''</big> <br />
----<br />
* '''Apr-10 We''' <br />
----<br />
* '''Apr-11 Th''' <br />
----<br />
* '''Apr-12 Fr'''<br />
<br />
2024 Week 16<br />
<br />
* '''Apr-15 Mo''' <br />
----<br />
* '''Apr-16 Tu''' <br />
----<br />
* '''Apr-17 We''' <br />
----<br />
* '''Apr-18 Th''' <br />
----<br />
* '''Apr-19 Fr'''<br />
<br />
2024 Week 17<br />
<br />
* '''Apr-22 Mo'''<br />
----<br />
* '''Apr-23 Tu''' <br />
----<br />
* '''Apr-24 We''' <br />
----<br />
* '''Apr-25 Th''' <br />
----<br />
* '''Apr-26 Fr'''<br />
<br />
2024 Week 18<br />
<br />
* '''Apr-29 Mo'''<br />
----<br />
* '''Apr-30 Tu''' <br />
----<br />
* '''May-01 We''' <br />
----<br />
* '''May-02 Th''' <br />
----<br />
* '''May-03 Fr'''<br />
<br />
2024 Week 19<br />
<br />
* '''May-06 Mo'''<br />
----<br />
* '''May-07 Tu''' <br />
----<br />
* '''May-08 We''' <br />
----<br />
* '''May-09 Th''' <br />
----<br />
* '''May-10 Fr'''<br />
<br />
2024 Week 20<br />
<br />
* '''May-13 Mo'''<br />
----<br />
* '''May-14 Tu''' <br />
----<br />
* '''May-15 We''' <br />
----<br />
* '''May-16 Th''' <br />
----<br />
* '''May-17 Fr'''<br />
<br />
2024 Week 21<br />
<br />
* '''May-20 Mo''' <br />
----<br />
* ''May-21 Tu''' <br />
----<br />
* '''May-22 We''' <br />
----<br />
* '''May-23 Th''' <br />
----<br />
* '''May-24 Fr'''<br />
<br />
2024 Week 22<br />
<br />
* '''May-27 Mo'''<br />
----<br />
* '''May-28 Tu''' <br />
----<br />
* '''May-29 We''' <br />
----<br />
* '''May-30 Th''' <br />
----<br />
* '''May-31 Fr'''<br />
<br />
2024 Week 23<br />
<br />
* '''Jun-03 Mo'''<br />
----<br />
* '''Jun-04 Tu''' <br />
----<br />
* '''Jun-05 We''' <br />
----<br />
* '''Jun-06 Th''' <br />
----<br />
* '''Jun-07 Fr'''<br />
<br />
2024 Week 24<br />
<br />
* '''Jun-10 Mo'''<br />
----<br />
* '''Jun-11 Tu''' <br />
----<br />
* '''Jun-12 We''' <br />
----<br />
* '''Jun-13 Th''' <br />
----<br />
* '''Jun-14 Fr'''<br />
<br />
2024 Week 25<br />
<br />
* '''Jun-17 Mo'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
<br />
----<br />
* '''Jun-18 Tu''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-19 We''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-20 Th''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
----<br />
* '''Jun-21 Fr'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC162 Schroecken AT]] <big> '''[[MiPNet28.11 IOC163 Schroecken AT]]'''</big> Jun 17-22<br />
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2024 Week 26<br />
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* '''Jun-24 Mo'''<br />
----<br />
* '''Jun-25 Tu''' <br />
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* '''Jun-26 We''' <br />
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* '''Jun-27 Th''' <br />
----<br />
* '''Jun-28 Fr'''<br />
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2024 Week 27<br />
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* '''Jul-01 Mo'''<br />
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* '''Jul-02 Tu''' <br />
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* '''Jul-03 We''' <br />
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* '''Jul-04 Th''' <br />
----<br />
* '''Jul-05 Fr'''<br />
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2024 Week 28<br />
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* '''Jul-08 Mo'''<br />
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* '''Jul-09 Tu''' <br />
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* '''Jul-10 We''' <br />
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* '''Jul-11 Th''' <br />
----<br />
* '''Jul-12 Fr'''<br />
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2024 Week 29<br />
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* '''Jul-15 Mo'''<br />
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* '''Jul-16 Tu''' <br />
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* '''Jul-17 We''' <br />
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* '''Jul-18 Th''' <br />
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* '''Jul-19 Fr'''<br />
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2024 Week 30<br />
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* '''Jul-22 Mo'''<br />
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* '''Jul-23 Tu''' <br />
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* '''Jul-24 We''' <br />
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* '''Jul-25 Th''' <br />
----<br />
* '''Jul-26 Fr'''<br />
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2024 Week 31<br />
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* '''Jul-29 Mo'''<br />
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* '''Jul-30 Tu''' <br />
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* '''Jul-31 We''' <br />
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* '''Aug-01 Th''' <br />
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* '''Aug-02 Fr'''<br />
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2024 Week 32<br />
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* '''Aug-05 Mo'''<br />
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* '''Aug-06 Tu''' <br />
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* '''Aug-07 We''' <br />
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* '''Aug-08 Th''' <br />
----<br />
* '''Aug-09 Fr'''<br />
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2024 Week 33<br />
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* '''Aug-12 Mo'''<br />
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* '''Aug-13 Tu''' <br />
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* '''Aug-14 We''' <br />
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* '''Aug-15 Th''' <br />
----<br />
* '''Aug-16 Fr'''<br />
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2024 Week 34<br />
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* '''Aug-19 Mo'''<br />
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* '''Aug-20 Tu''' <br />
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* '''Aug-21 We''' <br />
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* '''Aug-22 Th''' <br />
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* '''Aug-23 Fr'''<br />
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2024 Week 35<br />
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* '''Aug-26 Mo'''<br />
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* '''Aug-27 Tu''' <br />
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* '''Aug-28 We''' <br />
----<br />
* '''Aug-29 Th''' <br />
----<br />
* '''Aug-30 Fr'''<br />
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2024 Week 36<br />
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* '''Sep-02 Mo'''<br />
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* '''Sep-03 Tu''' <br />
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* '''Sep-04 We''' <br />
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* '''Sep-05 Th''' <br />
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* '''Sep-06 Fr'''<br />
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2024 Week 37<br />
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* '''Sep-09 Mo'''<br />
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* '''Sep-10 Tu''' <br />
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* '''Sep-11 We''' <br />
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* '''Sep-12 Th''' <br />
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* '''Sep-13 Fr'''<br />
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2024 Week 38<br />
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* '''Sep-16 Mo'''<br />
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* '''Sep-17 Tu''' <br />
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* '''Sep-18 We''' <br />
----<br />
* '''Sep-19 Th''' <br />
----<br />
* '''Sep-20 Fr'''<br />
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2024 Week 39<br />
<br />
* '''Sep-22 Su'''<br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
* '''Sep-23 Mo'''<br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-24 Tu''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-25 We''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-26 Th''' <br />
::::: <big> '''[[EMC2024 Ljubljana SI]]'''</big> 2024 Sep 22-26 <br />
----<br />
* '''Sep-27 Fr'''<br />
<br />
<br />
2024 Week 40<br />
<br />
* '''Sep-30 Mo'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-01 Tu''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-02 We''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-03 Th''' <br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
----<br />
* '''Okt-04 Fr'''<br />
:::: [[Image:O2k-Workshops.png|60px|link=MiPNet28.02 IOC164 Schroecken AT]] <big> '''[[MiPNet28.12 IOC164 Schroecken AT]]'''</big> Sep 30-Okt 05<br />
<br />
2024 Week 41<br />
<br />
* '''Okt-07 Mo'''<br />
----<br />
* '''Okt-08 Tu''' <br />
----<br />
* '''Okt-09 We''' <br />
----<br />
* '''Okt-10 Th''' <br />
----<br />
* '''Okt-11 Fr'''<br />
<br />
2024 Week 42<br />
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* '''Okt-14 Mo'''<br />
----<br />
* '''Okt-15 Tu''' <br />
----<br />
* '''Okt-16 We''' <br />
----<br />
* '''Okt-17 Th''' <br />
----<br />
* '''Okt-18 Fr'''<br />
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2024 Week 43<br />
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* '''Okt-21 Mo'''<br />
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* '''Okt-22 Tu''' <br />
----<br />
* '''Okt-23 We''' <br />
----<br />
* '''Okt-24 Th''' <br />
----<br />
* '''Okt-25 Fr'''<br />
::::: <big> '''[[14th Mitochondrial Disease Conference 2024 Padova IT]]'''</big> 2024 Oct 25-27<br />
<br />
2024 Week 44<br />
<br />
* '''Okt-28 Mo'''<br />
----<br />
* '''Okt-29 Tu''' <br />
----<br />
* '''Okt-30 We''' <br />
----<br />
* '''Okt-31 Th''' <br />
----<br />
* '''Nov-01 Fr''' <br />
<br />
2024 Week 45<br />
<br />
* '''Nov-04 Mo'''<br />
----<br />
* '''Nov-05 Tu''' <br />
----<br />
* '''Nov-06 We''' <br />
----<br />
* '''Nov-07 Th''' <br />
----<br />
* '''Nov-08 Fr'''<br />
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2024 Week 46<br />
<br />
* '''Nov-11 Mo'''<br />
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* '''Nov-12 Tu''' <br />
----<br />
* '''Nov-13 We''' <br />
----<br />
* '''Nov-14 Th''' <br />
----<br />
* '''Nov-15 Fr'''<br />
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<br />
2024 Week 47<br />
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* '''Nov-18 Mo'''<br />
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* '''Nov-19 Tu''' <br />
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* '''Nov-20 We''' <br />
----<br />
* '''Nov-21 Th''' <br />
----<br />
* '''Nov-22 Fr'''<br />
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2024 Week 48<br />
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* '''Nov-25 Mo'''<br />
----<br />
* '''Nov-26 Tu''' <br />
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* '''Nov-27 We''' <br />
----<br />
* '''Nov-28 Th''' <br />
----<br />
* '''Nov-29 Fr'''<br />
<br />
2024 Week 49<br />
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* '''Dez-02 Mo'''<br />
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* '''Dez-03 Tu''' <br />
----<br />
* '''Dez-04 We''' <br />
----<br />
* '''Dez-05 Th''' <br />
----<br />
* '''Dez-06 Fr'''<br />
<br />
2024 Week 50<br />
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* '''Dez-09 Mo'''<br />
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* '''Dez-10 Tu''' <br />
----<br />
* '''Dez-11 We''' <br />
----<br />
* '''Dez-12 Th''' <br />
----<br />
* '''Dez-13 Fr'''<br />
<br />
2024 Week 51<br />
<br />
* '''Dez-16 Mo'''<br />
----<br />
* '''Dez-17 Tu''' <br />
----<br />
* '''Dez-18 We''' <br />
----<br />
* '''Dez-19 Th''' <br />
----<br />
* '''Dez-20 Fr'''<br />
<br />
2024 Week 52<br />
<br />
* '''Dez-23 Mo'''<br />
----<br />
* '''Dez-24 Tu''' <br />
----<br />
* '''Dez-25 We''' <br />
----<br />
* '''Dez-26 Th''' <br />
----<br />
* '''Dez-27 Fr'''</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Current_week_ecosystem_agenda&diff=246254
Template:Current week ecosystem agenda
2024-02-28T15:41:01Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:Science for Ukraine}}<br />
2024 Week 09<br />
<br />
* '''Feb-26 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' ATP synthase = phosphorylation system? '''<br><br />
No, the phosphorylation system consists of adenine nucleotide translocase, phosphate carrier, and ATP synthase, which carry out the steps in the phosphorylation pathway. <br><br />
- »'''[[Phosphorylation pathway]]'''«, »'''[https://www.bioblast.at/index.php/Gnaiger_2020_BEC_MitoPathways Mitochondrial Pathways: Chapter 2.2]'''« <br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Feb-27 Tu''' <br />
----<br />
* '''Feb-28 We''' <br />
----<br />
* '''Feb-29 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Bed rest results in a decrease in skeletal muscle mitochondrial respiratory capacity, mainly as a result of an observed decrease in mitochondrial content"''' <br><br />
* Noone J, Damiot A, Kenny H, Chery I, Zahariev A, Normand S, Crampes F, de Glisezinski I, Rochfort KD, Laurens C, Bareille MP, Simon C, Bergouignan A, Blanc S, O'Gorman DJ (2023) The impact of 60 days of -6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics. [[Noone 2023 J Physiol|»Bioblast link«]]<br />
:from the O2k-Networks »[[US FL Orlando Goodpaster BH]]« , »[[FR Strasbourg Blanc S]]« , »[[IE Dublin O Gorman D]]«<br />
|}<br />
----<br />
* '''Mar-01 Fr''' <br />
----<br />
<br />
'''<big>Next Week</big>'''<br />
2024 Week 10<br />
<br />
* '''Mar-04 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test? '''<br><br />
Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.<br />
<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
* '''Mar-05 Tu''' <br />
----<br />
* '''Mar-06 We''' <br />
:{|<br />
| width="100" align="center" |[[File:BEC2024.1.jpg|right|150px|link=https://doi.org/10.26124/bec:2024-0001 |Gross 2024 BEC]]<br />
|'''The tale of two “best-friends,” proteins BID & MTCH2, pivotal regulators of the apoptosis and metabolism programs at the mitochondria.''' <br><br />
* Gross A, (2024) A BID-MTCH2 love story: Energizing mitochondria until apoptosis do them part? Bioenerg Commun 2024.1. https://doi.org/10.26124/bec:2024-0001<br />
|}<br />
----<br />
* '''Mar-07 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Which medium can be used for the instrumental background test?'''<br><br />
When using dithionite, the instrumental background test should be performed in mitochondrial respiration medium MiR05, MiR05-Kit or MiR06; or alternatively, in a strong alkaline phosphate buffer (>100 mM; >pH 8), to avoid side reactions that might interfere with the test.<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background]]'''«<br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
<br />
----<br />
* '''Mar-08 Fr''' <br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template_talk:Next_oroboros_ecosystem_agenda&diff=246241
Template talk:Next oroboros ecosystem agenda
2024-02-27T15:25:27Z
<p>Tindle Lisa: /* MiPNet */</p>
<hr />
<div>__TOC__<br />
<br />
::::[[User:Antunes Diana|Antunes Diana]] ([[User talk:Antunes Diana|talk]]) 08:58, 5 May 2020 (CEST) Format for new Agenda/Alerts entries:<br />
<pre style="display: inline-block;"><br />
{|<br />
| logos<br />
| title in bold <br><br />
- link<br />
|}<br />
</pre><br />
<br />
''e.g.,''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Red-loss of data.png|25px|Warning: loss of data]]<br />
|'''Did you know that the proper use of TIP2k-Filter Papers may avoid an unstable O2 slope neg. signal during Instrumental background correction?''' <br><br />
- »[[Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._signal_in_O2_instrumental_BG|Instrumental background]]« and »[[TIP2k Filter Papers]]«<br />
|}<br />
:::: ''See the scheme'':<br />
<br><br />
[[Image:TEMPLATE ALERT.png|none|900px|Agenda/Alerts body text format]]<br />
<br />
<br />
== MitoPedia alert ==<br />
::: Example:<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Measuring fatty acid oxidation (FAO)-linked respiration requires a low concentration of malate '''<br><br />
In the absence of malate, accumulation of Acetyl-CoA inhibits FAO. <br><br />
- »'''[[Fatty acid oxidation pathway control state]]'''«, »'''[https://www.bioblast.at/index.php/Gnaiger_2020_BEC_MitoPathways Mitochondrial Pathways: Chapter 5]'''« <br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Cardoso Luiza]]« <br />
|}<br />
<br />
<br />
=== Next ===<br />
<br />
March 11th<br />
<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' Why is it important to perform respirometry with permeabilized muscle fibers (pfi) under a high [O<sub>2</sub>] regime? '''<br><br />
Long diffusion distances in the pfi result in an O<sub>2</sub> diffusion limitation, which is overcome by increasing the O<sub>2</sub> partial pressure inside the chamber. Proper instrumental background correction is a must and O<sub>2</sub> dependence of ROS production should be considered. <br><br />
- »'''[[Permeabilized muscle fibers]]'''«, »'''[[Oxygen flux - instrumental background]]'''« <br><br />
- communicated by »[[Grings Mateus]]« and »[[Cardoso Luiza]]« <br />
|}<br />
<br />
=== Under construction ===<br />
<br />
on hold until the page is updated<br />
:{|<br />
| width="100" align="center" |[[File:FAT4BRAIN logo.png|right|80px|link=https://wiki.oroboros.at/index.php/FAT4BRAIN|FAT4BRAIN]]<br />
|'''A FAO-mito-CNS platform to help fatty acid-related respiration measurements was developed in the FAT4BRAIN project''' <br><br />
- » [[FAT4BRAIN_FAO-mito-CNS_platform|FAT4BRAIN FAO-mito-CNS platform]] «<br />
|}<br />
<br />
== O2k-Brief alert ==<br />
:::* Example:<br />
:{|<br />
| width="100" align="center" | [[File:O2k-brief.png|45px|link=http://wiki.oroboros.at/index.php/O2k-brief|O2k-brief repository]]<br />
|'''Antitumoral properties of triterpenic acid functionalized gold nanoparticles arise from decreasing mitochondrial respiration''' <br><br />
* Mioc M, Mioc A, Racoviceanu R, Ghiulai R, Prodea A, Milan A, Barbu Tudoran L, Oprean C, Ivan V, Șoica C (2023) The antimelanoma biological assessment of triterpenic acid functionalized gold nanoparticles. [[Mioc 2023 Molecules|»Bioblast link«]]<br />
|}<br />
=== Next ===<br />
<br />
== O2k-Publications alert ==<br />
<br />
:::* Example: <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Mitochondria–nucleus communication and its integration within the maintenance of cellular homeostasis constitute key determinants of cellular fate and organism health in the context of cellular stress, homeostasis perturbation, and disease"''' <br><br />
* Temelie M, Talpur R, Dominguez-Prieto M, Dantas Silva A, Cenusa C, Craciun L, Savu DI, Moisoi N (2023) Impaired integrated stress response and mitochondrial integrity modulate genotoxic stress impact and lower the threshold for immune signalling. [[Temelie 2023 Int J Mol Sci|»Bioblast link«]]<br />
:from the O2k-Network »[[UK Leicester Moisoi N]]«<br />
|}<br />
<br />
===='''Author names of O2k-Publications/ Brief for the Agenda vs Bioblast''' ==== <br />
<br />
__NOTOC__ [[File:Expand.png|right|25px|Click to expand or collaps]]<br />
<div class="toccolours mw-collapsible mw-collapsed"><br />
'''Guidelines to update a reference'''<br />
<div class="mw-collapsible-content"><br />
::When creating an O2k-Publication/Brief alert, it is the responsibility of the author to check if the reference is accordingly to the correct guidelines:<br />
[[File:Reference example.png|900px]]<br />
::Correct format for a person called “First Name Surname”: <br />
::In the gray box should be “Surname FN” - '''From where references to be used as O2k-Publication/Brief alerts are copied from.'''<br />
[[File:Gray box reference.png|900px]]<br />
::In the links should be “ Surname First N”<br />
[[File:Authors names links reference.png|900px]]<br />
::'''How to edit:'''<br />
:::A) Check if all authors with profiles in Bioblast (blue links) have their profiles with full name. If they have, proceed to next step (B). If not, you need to move it following the steps “How to move a profile” below.<br />
:::B) Click in “Edit with form”.<br />
:::C) The gray box is edited in “Reference” and the links are changed in “Author(s)”. Change it accordingly and click in “save page” at the end of the page.<br />
[[File:Editing reference.png|900px]]<br />
<br />
'''How to move a profile (instructions sent by Marija):'''<br />
<br />
So let’s take for example my page: <br />
[[Beno M]] <br />
[https://wiki.oroboros.at/index.php?title=Beno_Marija&redirect=no]<br />
<br />
::As you can see there is a redirect from Beno Marija to Beno M. What has to be done is to switch the content of those pages. Here are the steps: <br />
:::1. Go to e.g. “Beno M” on edit<br />
:::2. Click on “Move”<br />
:::3. Change the new title to the full name of the person. In my case it will be Beno M to Beno Marija <br />
[[File:BenoMreference.jpg|500px]]<br />
:::4. Now it should look like that: <br />
[[File:BenoMarijaReference.png|500px]]<br />
:::5. Click on “Move” and leave all the ticked boxes<br />
:::6.Done<br />
::After that you can continue in step B.<br />
::If you have any doubt you can contact Cristiane, Marija or Mario.<br />
</div><br />
</div><br />
<br />
=== Next ===<br />
<br />
:{|<br />
| width="100" align="center" |[[File:BEC2023.3.jpg|right|150px|link=https://doi.org/10.26124/bec:2023-0004| Oliveira 2023 BEC]]<br />
|'''A BEC Spotlight on Rodríguez et al's ''Drosophila'' mitochondrial research methodology''' <br><br />
* Oliveira MF, Aveiro Y, Couto-Lima CA (2023) A navigation chart to avoid turbulence in Drosophila mitochondrial research. Bioenerg Commun 2023.4. https://doi.org/10.26124/bec:2023-0004<br />
:from the O2k-Network »[[BR Rio de Janeiro Oliveira MF]]«<br />
|}<br />
<br />
March 14th<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''Mitochondrial ultrastructure and respiration are affected during EDL [''Extensor digitorum longus'' muscle] aging.''' <br><br />
* Fernando R, Shindyapina AV, Ost M, Santesmasses D, Hu Y, Tyshkovskiy A, Yim SH, Weiss J, Gladyshev VN, Grune T, Castro JP (2023) Downregulation of mitochondrial metabolism is a driver for fast skeletal muscle loss during mouse aging. [[Fernando 2023 Commun Biol|»Bioblast link«]]<br />
:from the O2k-Network »[[DE Leipzip Ost M]]«<br />
|}<br />
<br />
== MiPNet ==<br />
:::* Example: <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' "No bubbles should be trapped in the electrolyte reservoir after membrane application and mounting"'''<br><br />
<br />
- »'''[[MiPNet28.10 SmartPOS-service]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[]]«<br />
|}<br />
<br />
=== Next ===<br />
<br />
== O2k-Open Support alert ==<br />
:::*Examples:<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Yellow-take care.png|25px|Info: take care]]<br />
|'''Does your polarographic oxygen sensor (POS) need a deep clean?'''<br><br />
A POS with a very dark anode might need several rounds of ammonia cleaning, possibly including prolonged exposure overnight to restore performance specifications. <br />
<br><br />
- »'''[[MiPNet19.18B POS-service|POS service]]'''«<br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Leo Elettra]]«<br />
|}<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Red-loss of data.png|25px|Warning: loss of data]] <br />
|'''Did you know that a humid environment and/or liquid spillage may lead to a high raw POS signal [V]?'''<br><br />
See how to clean and dry the electrical connections of the OroboPOS-Connector.<br><br />
- »'''[[OroboPOS-Connector#Cleaning_the_electrical_connections|Cleaning the electrical connections]]'''«<br><br />
- communicated by »[[Cecatto Cristiane]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Unusual stirrer bar rotation? '''<br><br />
A “jumping” stirrer or a slow rotation of the stirrer bar may indicate a problem either with the stirrer itself or with the cleaning of the glass chamber. <br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/Stirrer-Bar%5Cwhite_PVDF%5C15x6_mm#Technical_support Stirrer bar - technical support]'''«<br><br />
- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«<br />
|}<br />
<br />
=== Next ===<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' How to store the POS overnight and up to several months? '''<br><br />
Fill the chamber and the receptacle of the loosely inserted stopper with 70 % EtOH, add the Cover-slip and switch off the O2K.<br />
<br><br />
- »'''[https://wiki.oroboros.at/index.php/MiPNet19.03_O2k-cleaning_and_ISS O2k-cleaning and ISS]'''«<br><br />
- communicated by »[[Leo Elettra]]« and »[[Grings Mateus]]«<br />
|}<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test? '''<br><br />
Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.<br />
<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
<br />
March 18<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' What if ''Alert: Error in titrations!'' appears in your O2 analysis template file? '''<br><br />
The O2 analysis template recognizes discrepancies between the protocol selected in the first tab and the imported marks. Check the titration sequence and mark names against the protocol copied from the DLD file.<br><br />
- »'''[[MiPNet24.06 Oxygen flux analysis - DatLab 7.4|O<sub>2</sub> flux analysis]]'''«<br><br />
- communicated by »[[Timon-Gomez Alba]]« and »[[Leo Elettra]]«<br />
|}<br />
<br />
== O2k-Feedback alert ==<br />
:::* Example (if the person has a profile, link the name to the profile with [[Cecatto C| Cristiane Cecatto]]:<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“Thank you very much for your thorough help. I appreciate the time you took to provide me with all the answers and supportive literature to realize the potential of the O2k-respirometer in bioenergetics research”'''''<br><br />
Badr Ibrahim, PhD from Betterhumans Inc., US<br />
<br><br />
- »'''[[O2k-Feedback]]'''«<br><br />
|}<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]<br />
|''' ''“Thank you very much for your thorough help. I appreciate the time you took to provide me with all the answers and supportive literature to realize the potential of the O2k-respirometer in bioenergetics research”'''''<br><br />
Badr Ibrahim, PhD from the O2k-Network »[[UK Leicester Moisoi N]]«<br><br />
- »'''[[O2k-Feedback]]'''«<br><br />
|}<br />
<br />
=== Next ===<br />
<br />
== MitoFit Preprints ==<br />
:::* Example:<br />
:{|<br />
| width="100" align="center"|[[Image:BEC-logo.png|100px|link=https://www.bioenergetics-communications.org/index.php/bec |Bioenergetics Communications]]<br />
|'''From preprint to BEC manuscript with published Open Peer Reviews:'''<br><br />
*Komlódi T, Sobotka O, Gnaiger E (2021) Facts and artefacts on the oxygen dependence of hydrogen peroxide production using Amplex UltraRed. Bioenerg Commun 2021.4. [[doi:10.26124/BEC:2021-0004]]<br />
:from the O2k-Network »[[AT Innsbruck Oroboros]]« <br />
|}<br />
<br />
=== Next ===<br />
<br />
== Under discussion ==<br />
<br />
This one needs an update of the Bioblast page and clarification of MiPNet06.03<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Did you enter the correct oxygen solubility factor in DatLab?'''<br><br />
The oxygen solubility factor of the incubation medium, F<sub>M</sub>, expresses the effect of the salt concentration on oxygen solubility relative to pure water. The correct oxygen solubility factor of your experimental medium or buffer needs to be entered in DatLab for proper calculation of the oxygen concentration.<br />
<br><br />
- »'''[[Oxygen solubility factor|Oxygen solubility factor]]'''«<br><br />
- communicated by »[[Schmitt Sabine]]« and »[[ ]]«<br />
<br />
|}<br />
<br />
This one needs a BioBlast link:<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' When filling in the volume of uncoupler in the DatLab mark or the excel template, should one enter the total volume added or the volume to get to the highest flux?'''<br><br />
The volume added until the mark, equal to the highest flux, should be entered. Anything titrated after this mark should be summed to the other volumes before the next mark because this will be considered to calculate the sample dilution. <br />
<br><br />
- »'''[[LINK|LINK]]''' and '''[[MiPNet24.06_Oxygen_flux_analysis_-_DatLab_7.4|O<sub>2</sub> flux analysis with DatLab 7.4]]'''«<br><br />
- communicated by »[[Cardoso Luiza]]« and »[[ ]]«<br />
|}<br />
<br />
<br />
== Removed for correction ==<br />
* '''Nov-30 Mo''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|'''Noisy oxygen signal? Check the OroboPOS and OroboPOS-Connector to clean electrical connections.'''<br><br />
Contaminating grease, salt crystals and moisture can be removed with a dry paper cloth or a paper cloth moistened with water and then absolute ethanol. <br><br />
- »[[OroboPOS-Connector#Cleaning_the_electrical_connections |Cleaning the electrical connections]]« <br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Komlodi Timea]]«<br />
|}<br />
WGT recommended not to use water for cleaning. Erich introduced water for cleaning to remove salt crystals.<br />
<br />
<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Red-loss of data.png|25px|Warning: loss of data]]<br />
|'''Do you perform the ''leaky chamber test'' after chamber assembly? '''<br><br />
An unnoticed leak from the chamber may affect your data, therefore we recommend performing the ''Leaky chamber test'' - especially after chamber reassembly. <br><br />
- »[[Talk:O2k-Chamber_MitoPedia#Leaky_Chamber|Leaky chamber test]]« and » https://intern.oroboros.at/index.php/Overnight_test_after_O2k-chamber_assembly«<br />
|}</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:Current_week_ecosystem_agenda&diff=246237
Template:Current week ecosystem agenda
2024-02-27T13:59:40Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:Science for Ukraine}}<br />
2024 Week 09<br />
<br />
* '''Feb-26 Mo'''<br />
:{|<br />
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]<br />
|''' ATP synthase = phosphorylation system? '''<br><br />
No, the phosphorylation system consists of adenine nucleotide translocase, phosphate carrier, and ATP synthase, which carry out the steps in the phosphorylation pathway. <br><br />
- »'''[[Phosphorylation pathway]]'''«, »'''[https://www.bioblast.at/index.php/Gnaiger_2020_BEC_MitoPathways Mitochondrial Pathways: Chapter 2.2]'''« <br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]« <br />
|}<br />
----<br />
* '''Feb-27 Tu''' <br />
----<br />
* '''Feb-28 We''' <br />
----<br />
* '''Feb-29 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Bed rest results in a decrease in skeletal muscle mitochondrial respiratory capacity, mainly as a result of an observed decrease in mitochondrial content"''' <br><br />
* Noone J, Damiot A, Kenny H, Chery I, Zahariev A, Normand S, Crampes F, de Glisezinski I, Rochfort KD, Laurens C, Bareille MP, Simon C, Bergouignan A, Blanc S, O'Gorman DJ (2023) The impact of 60 days of -6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics. [[Noone 2023 J Physiol|»Bioblast link«]]<br />
:from the O2k-Networks »[[US FL Orlando Goodpaster BH]]« , »[[FR Strasbourg Blanc S]]« , »[[IE Dublin O Gorman D]]«<br />
|}<br />
----<br />
* '''Mar-01 Fr''' <br />
----<br />
<br />
'''<big>Next Week</big>'''<br />
2024 Week 10<br />
<br />
* '''Mar-04 Mo'''<br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Do you observe an unstable O<sub>2</sub> slope negative following TIP2k titrations during an instrumental O<sub>2</sub> background test? '''<br><br />
Incorrect placement of TIP2k Filter Papers can lead to liquid accumulation and convective oxygen backdiffusion. Check for proper placement by confirming they are fully in contact with the stopper receptacle.<br />
<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background|Instrumental O<sub>2</sub> background]]'''«, »'''[https://wiki.oroboros.at/index.php/Oxygen_flux_-_instrumental_background#Unstable_O2_slope_neg._in_instrumental_background_test Unstable O<sub>2</sub> slope negative]'''«<br><br />
- communicated by »[[Grings Mateus]]« and »[[Baglivo Eleonora]]«<br />
|}<br />
----<br />
* '''Mar-05 Tu''' <br />
----<br />
* '''Mar-06 We''' <br />
----<br />
* '''Mar-07 Th''' <br />
:{|<br />
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]<br />
|''' Which medium can be used for the instrumental background test?'''<br><br />
When using dithionite, the instrumental background test should be performed in mitochondrial respiration medium MiR05, MiR05-Kit or MiR06; or alternatively, in a strong alkaline phosphate buffer (>100 mM; >pH 8), to avoid side reactions that might interfere with the test.<br><br />
- »'''[[MiPNet14.06_Instrumental_O2_background]]'''«<br><br />
- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]«<br />
|}<br />
<br />
----<br />
* '''Mar-08 Fr''' <br />
----</div>
Tindle Lisa
https://wiki.oroboros.at/index.php?title=Template:O2k-PublicationAlert2024&diff=246177
Template:O2k-PublicationAlert2024
2024-02-26T07:52:07Z
<p>Tindle Lisa: </p>
<hr />
<div>{{Template:OROBOROS Slogan}}<br />
::::<big>» Listed in '''[[OROBOROS_INSTRUMENTS|Oroboros Ecosystem Agenda ]]'''</big><br />
__TOC__<br />
== Feb 2024 ==<br />
* '''Feb-29 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Bed rest results in a decrease in skeletal muscle mitochondrial respiratory capacity, mainly as a result of an observed decrease in mitochondrial content"''' <br><br />
* Noone J, Damiot A, Kenny H, Chery I, Zahariev A, Normand S, Crampes F, de Glisezinski I, Rochfort KD, Laurens C, Bareille MP, Simon C, Bergouignan A, Blanc S, O'Gorman DJ (2023) The impact of 60 days of -6° head down tilt bed rest on mitochondrial content, respiration and regulators of mitochondrial dynamics. [[Noone 2023 J Physiol|»Bioblast link«]]<br />
:from the O2k-Networks »[[US FL Orlando Goodpaster BH]]« , »[[FR Strasbourg Blanc S]]« , »[[IE Dublin O Gorman D]]«<br />
|}<br />
----<br />
* '''Feb-15 Th''' - International Childhood Cancer Day<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Deleterious mtDNA mutations contribute significantly to the tumorigenesis of pediatric cancers"''' <br><br />
* Triska P, Kaneva K, Merkurjev D, Sohail N, Falk MJ, Triche TJ Jr, Biegel JA, Gai X (2019) Landscape of germline and somatic mitochondrial DNA mutations in pediatric malignancies. [[Triska 2019 Cancer Res|»Bioblast link«]]<br />
:from the O2k-Network »[[US_PA_Philadelphia_Falk_MJ]]«<br />
|}<br />
----<br />
* '''Feb-05 Mo'''<br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"We demonstrated deficient platelet mitochondrial respiratory chain functions, oxidative phosphorylation (OXPHOS), and electron transfer (ET) capacity with complex I (CI)-linked substrates, and reduced [...] endogenous platelet coenzyme Q10 (CoQ10) concentration in UC [urothelial carcinoma] patients."''' <br><br />
* Palacka P, Gvozdjáková A, Rausová Z, Kucharská J, Slopovský J, Obertová J, Furka D, Furka S, Singh KK, Sumbalová Z (2021) Platelet mitochondrial bioenergetics reprogramming in patients with urothelial carcinoma. [[Palacka 2021 Int J Mol Sci|»Bioblast link«]]<br />
:from the O2k-Network »[[SK Bratislava Sumbalova Z]]«<br />
|}<br />
----<br />
== Jan 2024 ==<br />
<br />
* '''Jan-04 Th''' <br />
:{|<br />
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]<br />
|'''"Oxygen Consumption Rate (OCR) measurements of fresh and cryopreserved placental specimens are comparable whereas snap frozen procedure impairs mitochondrial activity"''' <br><br />
* Giovarelli M, Serati A, Zecchini S, Guelfi F, Clementi E, Mandò C (2023) Cryopreserved placental biopsies maintain mitochondrial activity for high-resolution respirometry. [[Giovarelli 2023 Mol Med|»Bioblast link«]]<br />
:from the O2k-Network »[[IT Milan Clementi E]]«<br />
|}<br />
----</div>
Tindle Lisa