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From Bioblast
| Year | Reference | Mammal and model | Tissue and cell | Stress | Diseases | |
|---|---|---|---|---|---|---|
| Achreja 2022 Nat Metab | 2022 | Achreja A, Yu T, Mittal A, Choppara S, Animasahun O, Nenwani M, Wuchu F, Meurs N, Mohan A, Jeon JH, Sarangi I, Jayaraman A, Owen S, Kulkarni R, Cusato M, Weinberg F, Kweon HK, Subramanian C, Wicha MS, Merajver SD, Nagrath S, Cho KR, DiFeo A, Lu X, Nagrath D (2022) Metabolic collateral lethal target identification reveals MTHFD2 paralogue dependency in ovarian cancer. Nat Metab 4:1119-37. https://doi.org/10.1038/s42255-022-00636-3 | Cancer | |||
| Acuna-Castroviejo 2012 Abstract Bioblast | Acuna-Castroviejo D (2012) Melatonin and the quality of life: the melatonin-mitochondrion connection. Mitochondr Physiol Network 17.12. | Mouse Rat | Heart Skeletal muscle Nervous system Liver | Oxidative stress;RONS | Aging;senescence Alzheimer's Cancer Neurodegenerative Parkinson's Sepsis | |
| Acuña-Castroviejo 2012 Age (Dordr) | 2012 | Acuña-Castroviejo D, Carretero M, Doerrier C, López LC, García-Corzo L, Tresguerres JA, Escames G (2012) Melatonin protects lung mitochondria from aging. Age (Dordr) 34(3):681-92. | Mouse | Lung;gill | Aging;senescence | |
| Affourtit 2012 Methods Mol Biol | 2012 | Affourtit C, Quinlan CL, Brand MD (2012) Measurement of proton leak and electron leak in isolated mitochondria. Methods Mol Biol 810:165-82. | Rat | Skeletal muscle | Oxidative stress;RONS | |
| Agil 2015 J Pineal Res | 2015 | Agil A, El-Hammadi M, Jiménez-Aranda A, Tassi M, Abdo W, Fernández-Vázquez G, Reiter RJ (2015) Melatonin reduces hepatic mitochondrial dysfunction in diabetic obese rats. J Pineal Res 59:70-9. | Rat | Liver | Diabetes Obesity | |
| Ahting 2009 Biochim Biophys Acta | 2009 | Ahting U, Floss T, Uez N, Schneider-Lohmar I, Becker L, Kling E, Iuso A, Bender A, de Angelis MH, Gailus-Durner V, Fuchs H, Meitinger T, Wurst W, Prokisch H, Klopstock T (2009) Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import. Biochim Biophys Acta 1787:371-76. | Mouse | Stem cells | Other | |
| Ajime 2020 Nicotine Tob Res | 2020 | Ajime TT, Serré J, Wüst RCI, Messa GAM, Poffé C, Swaminathan A, Maes K, Janssens W, Troosters T, Degens H, Gayan-Ramirez G (2020) Two weeks smoking cessation reverses cigarette smoke-induced skeletal muscle atrophy and mitochondrial dysfunction in mice. Nicotine Tob Res 23:143-51. | Mouse | Skeletal muscle | ||
| Alandijany 2013 J Neurovirol | 2013 | Alandijany T, Kammouni W, Roy Chowdhury SK, Fernyhough P, Jackson AC (2013) Mitochondrial dysfunction in rabies virus infection of neurons. J Neurovirol 19:537-49. | Rat | Nervous system | Oxidative stress;RONS | Infectious |
| Allard 2018 J Clin Endocrinol Metab | 2018 | Allard NAE, Schirris TJJ, Verheggen RJ, Russel FGM, Rodenburg RJ, Smeitink JAM, Thompson PD, Hopman MTE, Timmers S (2018) Statins affect skeletal muscle performance: evidence for disturbances in energy metabolism. J Clin Endocrinol Metab 103:75-84. | Human | Skeletal muscle | Myopathy | |
| Alston 2017 J Pathol | 2017 | Alston CL, Rocha MC, Lax NZ, Turnbull DM, Taylor RW (2017) The genetics and pathology of mitochondrial disease. J Pathol 241:236-50. https://doi.org/10.1002/path.4809 | ||||
| Alvarez 2019 Chem Biol Interact | 2019 | Álvarez Santos MR, Duarte YB, Güiza FM, Romero Bohórquez AR, Mendez-Sanchez SC (2019) Effects of new tetrahydroquinoline-isoxazole hybrides on bioenergetics of hepatocarcinoma Hep-G2 cells and rat liver mitochondria. Chem Biol Interact 302:164-71. | Human | Liver | Cancer | |
| Amaral 2016 Biochim Biophys Acta | 2016 | Amaral AU, Cecatto C, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Wajner M (2016) cis-4-Decenoic and decanoic acids impair mitochondrial energy, redox and Ca2+ homeostasis and induce mitochondrial permeability transition pore opening in rat brain and liver: Possible implications for the pathogenesis of MCAD deficiency. Biochim Biophys Acta 1857:1363-72. | Rat | Nervous system Liver | Permeability transition Oxidative stress;RONS | |
| Amoedo 2010 Abstract MiP2010 | Amoêdo ND, Rodrigues MF, Pezutto P, Lourenço MVC, Madeiro da Costa RF, Oliveira MF, Galina A, Rumjanek FD, El-Bacha T (2010) Metabolic reprogramming of lung cancer cell induced by sodium butyrate: Studies on mitochondrial physiology and bioenergetics. Mitochondr Physiol Network 15.06. | Human | Endothelial;epithelial;mesothelial cell Fibroblast | Cancer | ||
| Amoedo 2012 Abstract Bioblast | Amoedo ND, Rodrigues MF, Pereira SAS, Melo FH, Jasiulionis MG, Galina A, Rumjanek FD (2012) Mitochondrial function and bioenergetics during malignant transformation and metastasis. Mitochondr Physiol Network 17.12. | Mouse | Other cell lines | Cancer | ||
| Amoedo 2013 Abstract MiP2013 | Amoêdo ND, Rodrigues MF, Pereira S, Melo F, Jasiulionis M, Galina A, Rumjanek FD(2013) Comparative biochemistry of tumorigenesis: role of mitochondria in the metastatic process. Mitochondr Physiol Network 18.08. | Mouse | Endothelial;epithelial;mesothelial cell Other cell lines | Ischemia-reperfusion | Cancer | |
| Andersen 2014 Abstract IOC 2014-04 Schroecken | Andersen M, Vienberg SG, Novod JB, Brandauer J, Holst B, Treebak JT (2014) Nicotinamide phosphoribosyltransferase knockdown impairs mitochondrial function in mouse myoblasts. Mitochondr Physiol Network 19.02. | Mouse | Skeletal muscle Other cell lines | Diabetes Obesity | ||
| Anderson 2009 J Am Coll Cardiol | 2009 | Anderson EJ, Kypson AP, Rodriguez E, Anderson CA, Lehr EJ, Neufer PD (2009) Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart. J Am Coll Cardiol 54:1891-8. | Human | Heart | Oxidative stress;RONS Mitochondrial disease | Aging;senescence Diabetes |
| Anderson 2009 J Clin Invest | 2009 | Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin C-T, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD (2009) Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest 119:573-81. | Human Mouse Rat | Skeletal muscle | Oxidative stress;RONS | Diabetes |
| Angebault 2015 Am J Hum Genet | 2015 | Angebault C, Guichet PO, Talmat-Amar Y, Charif M, Gerber S, Fares-Taie L, Gueguen N, Halloy F, Moore D, Amati-Bonneau P, Manes G, Hebrard M, Bocquet B, Quiles M, Piro-Mégy C, Teigell M, Delettre C, Rossel M, Meunier I, Preising M, Lorenz B, Carelli V, Chinnery PF, Yu-Wai-Man P, Kaplan J, Roubertie A, Barakat A, Bonneau D, Reynier P, Rozet JM, Bomont P, Hamel CP, Lenaers G (2015) Recessive mutations in RTN4IP1 cause isolated and syndromic optic neuropathies. Am J Hum Genet 97:754-60. | Human | Endothelial;epithelial;mesothelial cell Fibroblast | Other | |
| Angebault 2018 Sci Signal | 2018 | Angebault C, Fauconnier J, Patergnani S, Rieusset J, Danese A, Affortit CA, Jagodzinska J, Mégy C, Quiles M, Cazevieille C, Korchagina J, Bonnet-Wersinger D, Milea D, Hamel C, Pinton P, Thiry M, Lacampagne A, Delprat B, Delettre C (2018) ER-mitochondria cross-talk is regulated by the Ca2+ sensor NCS1 and is impaired in Wolfram syndrome. Sci Signal 11:eaaq1380. | Human | Fibroblast | Neurodegenerative Inherited | |
| Anoar 2021 Front Neurosci | 2021 | Anoar S, Woodling NS, Niccoli T (2021) Mitochondria dysfunction in frontotemporal dementia/amyotrophic lateral sclerosis: lessons from Drosophila models. Front Neurosci 15:786076. https://doi.org/10.3389/fnins.2021.786076 | Drosophila | Neurodegenerative | ||
| Aoun 2012 Br J Nutr | 2012 | Aoun M, Feillet-Coudray C, Fouret G, Chabi B, Crouzier D, Ferreri C, Chatgilialoglu C, Wrutniak-Cabello C, Cristol JP, Carbonneau MA, Coudray C (2012) Rat liver mitochondrial membrane characteristics and mitochondrial functions are more profoundly altered by dietary lipid quantity than by dietary lipid quality: effect of different nutritional lipid patterns. Br J Nutr 107:647-59. | Rat | Liver | Other | |
| Aoun 2012 J Bioenerg Biomembr | 2012 | Aoun M, Fouret G, Michel F, Bonafos B, Ramos J, Cristol JP, Carbonneau MA, Coudray C, Feillet-Coudray C (2012) Dietary fatty acids modulate liver mitochondrial cardiolipin content and its fatty acid composition in rats with non alcoholic fatty liver disease. J Bioenerg Biomembr 44:439-52. | Rat | Liver | Other | |
| Aparicio-Trejo 2018 Free Radic Biol Med | 2018 | Aparicio-Trejo OE, Reyes-Fermín LM, Briones-Herrera A, Tapia E, León-Contreras JC, Hernández-Pando R, Sánchez-Lozada LG, Pedraza-Chaverri J (2018) Protective effects of N-acetyl-cysteine in mitochondria bioenergetics, oxidative stress, dynamics and S-glutathionylation alterations in acute kidney damage induced by folic acid. Free Radic Biol Med 130:379-96. | Rat | Kidney | Oxidative stress;RONS | Other |
| Aral 2018 MiP2018 |  Effects of melatonin treatment on LETM1 silenced mouse embryonic fibroblast cells. | Mouse | Fibroblast | Oxidative stress;RONS | ||
| Area-Gomez 2019 J Clin Invest | 2019 | Area-Gomez E, Guardia-Laguarta C, Schon EA, Przedborski S (2019) Mitochondria, OxPhos, and neurodegeneration: cells are not just running out of gas. J Clin Invest 129:34-45. https://doi.org/10.1172/JCI120848 | ||||
| Armstrong 2010 J Comp Physiol B | 2010 | Armstrong C, Staples JF (2010) The role of succinate dehydrogenase and oxaloacetate in mitochondrial metabolism during mammalian hibernation and arousal. J Comp Physiol B 180:775-83. | Other mammals | Liver | ||
| Arnold 2023 J Biol Chem | 2023 | Arnold PK, Finley LWS (2023) Regulation and function of the mammalian tricarboxylic acid cycle. J Biol Chem 299:102838. https://doi.org/10.1016/j.jbc.2022.102838 | ||||
| Asiri 2017 Thesis | 2017 | Asiri A (2017) Effects of asiatic acid on neurite outgrowth in Neuro-2a cells. Master's Thesis p42. | Mouse | Nervous system | Cancer | |
| Atallah 2022 Biomedicines | 2022 | Atallah R, Olschewski A, Heinemann A (2022) Succinate at the crossroad of metabolism and angiogenesis: roles of SDH, HIF1α and SUCNR1. Biomedicines 10:3089. https://doi.org/10.3390/biomedicines10123089 | ||||
| Aya 2022 Eur J Pharmacol | 2022 | Shiraki A, Oyama J, Shimizu T, Nakajima T, Yokota T, Node K (2022) Empagliflozin improves cardiac mitochondrial function and survival through energy regulation in a murine model of heart failure. Eur J Pharmacol 931: 175194. | Mouse | Heart | Cardiovascular | |
| Azzone 1961 J Biol Chem | 1961 | Azzone GF, Ernster L (1961) Demonstration of a requirement of high energy phosphate for the aerobic oxidation of succinate in liver mitochondria. J Biol Chem 236:1518-25. | Rat | Liver | ||
| Bajzikova 2013 Abstract IOC79 | Bajzikova M (2013) Mitochondrially targeted vitamin E succinate and its effects on mitochondrial oxidative phosphorylation system. Mitochondr Physiol Network 18.07. | Human | Other cell lines | Cancer | ||
| Bajzikova 2019 Cell Metab | 2019 | Bajzikova M, Kovarova J, Coelho AR, Boukalova S, Oh S, Rohlenova K, Svec D, Hubackova S, Endaya B, Judasova K, Bezawork-Geleta A, Kluckova K, Chatre L, Zobalova R, Novakova A, Vanova K, Ezrova Z, Maghzal GJ, Magalhaes Novais S, Olsinova M, Krobova L, An YJ, Davidova E, Nahacka Z, Sobol M, Cunha-Oliveira T, Sandoval-Acuña C, Strnad H, Zhang T, Huynh T, Serafim TL, Hozak P, Sardao VA, Koopman Werner JH, Ricchetti M, Oliveira PJ, Kolar F, Kubista M, Truksa J, Dvorakova-Hortova K, Pacak K, Gurlich R, Stocker R, Zhou Y, Berridge MV, Park S, Dong L, Rohlena J, Neuzil J (2019) Reactivation of dihydroorotate dehydrogenase-driven pyrimidine biosynthesis restores tumor growth of respiration-deficient cancer cells. Cell Metab 29:399-416. 10.1016/j.cmet.2018.10.014 | Mouse | Endothelial;epithelial;mesothelial cell Genital Other cell lines | Cancer | |
| Bal 2016 J Biol Chem | 2016 | Bal NC, Maurya SK, Singh S, Wehrens XH, Periasamy M (2016) Increased reliance on muscle based thermogenesis upon acute minimization of brown adipose tissue function. J Biol Chem 291:17247-57. | Mouse | Skeletal muscle | Temperature | |
| Bandmann 2013 Abstract MiP2013 | Bandmann O, Flinn LJ, Keatinge M, Bretaud S, Mortiboys H, Matsui H, De Felice E,, Brown L, McTighe A, Soellner R, Allen CE, Heath PR, Milo M, Reichert AS, Köster RW, Ingham PW (2013) TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiency. Mitochondr Physiol Network 18.08. | Zebrafish Fishes | Nervous system | Neurodegenerative Parkinson's | ||
| Banerjee 2022 FEBS J | 2022 | Banerjee R, Purhonen J, Kallijärvi J (2022) The mitochondrial coenzyme Q junction and Complex III: biochemistry and pathophysiology. FEBS J 289:6936-58. https://doi.org/10.1111/febs.16164 | ||||
| Bansal 2019 Academic Press | 2019 | Bansal A, Rashid C, Simmons RA (2019) Impact of fetal programming on mitochondrial function and susceptibility to obesity and type 2 diabetes. Academic Press In: Mitochondria in obesity and type 2 diabetes. Morio B, Pénicaud L, Rigoulet M (eds) Academic Press. https://doi.org/10.1016/B978-0-12-811752-1.00014-6 | ||||
| Bao 2021 Cells | 2021 | Bao MH, Wong CC (2021) Hypoxia, metabolic reprogramming, and drug resistance in liver cancer. Cells 10:1715. https://doi.org/10.3390/cells10071715 | ||||
| Barca 2018 Hum Mol Genet | 2018 | Barca E, Ganetzky RD, Potluri P, Juanola-Falgarona M, Gai X, Li D, Jalas C, Hirsch Y, Emmanuele V, Tadesse S, Ziosi M, Akman HO, Chung WK, Tanji K, McCormick E, Place E, Consugar M, Pierce EA, Hakonarson H, Wallace DC, Hirano M, Falk MJ (2018) USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis. Hum Mol Genet 27:3305-12. | Human | Fibroblast | Other Neurodegenerative | |
| Bastos Sant'Anna Silva 2018 Life Sciences Meeting 2018 Innsbruck AT | Effect of cell-permeable succinate and malonate prodrugs on mitochondrial respiration in prostate cancer cells. | Kidney Other cell lines HEK | Cancer | |||
| Bastos Sant'Anna Silva 2018 MiPschool Tromso C4 |  Role of succinate in prostate cancer cells: uptake and mitochondrial respiratory function. | Human | Genital | Cancer | ||
| Bastos Sant'Anna Silva 2018 TRANSMIT Bertinoro di Romagna IT | Cellular succinate transport and mitochondrial respiratory function in prostate cancer. | Human | HEK Genital | Cancer | ||
| Bastos Sant'Anna Silva 2019 Life Sciences Meeting 2019 Innsbruck AT | Cellular succinate transport and mitochondrial respiratory function in prostate cancer. | Human | Genital | Cancer | ||
| Beauchamp 2015 Biosci Rep | 2015 | Beauchamp B, Thrush AB, Quizi J, Antoun G, McIntosh N, Al-Dirbashi OY, Patti ME, Harper ME (2015) Undernutrition during pregnancy in mice leads to dysfunctional cardiac muscle respiration in adult offspring. Biosci Rep 35. pii:e00200. | Mouse | Heart Liver | Cardiovascular Diabetes Obesity | |
| Begriche 2011 J Hepatol | 2011 | Begriche K, Massart J, Robin MA, Borgne-Sanchez A, Fromenty B (2011) Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver. J Hepatol 54:773-94. https://doi.org/10.1016/j.jhep.2010.11.006 | ||||
| Beier 2015 FASEB J | 2015 | Beier UH, Angelin A, Akimova T, Wang L, Liu Y, Xiao H, Koike MA, Hancock SA, Bhatti TR, Han R, Jiao J, Veasey SC, Sims CA, Baur JA, Wallace DC, Hancock WW (2015) Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival. FASEB J 29:2315-26. https://doi.org/10.1096/fj.14-268409 | Mouse | Nervous system | ||
| Beinert 1960 Biochem Biophys Res Commun | 1960 | Beinert H, Sands RH (1960) Studies on succinic and DPNH dehydrogenase preparations by paramagnetic resonance (EPR) spectroscopy. Biochem Biophys Res Commun 3:41-6. | ||||
| Bellance 2009 Front Biosci (Landmark Ed) | 2009 | Bellance N, Lestienne P, Rossignol R (2009) Mitochondria: from bioenergetics to the metabolic regulation of carcinogenesis. Front Biosci (Landmark Ed) 14:4015-34. doi: 10.2741/3509 | Cancer | |||
| Belosludtsev 2018 Biochim Biophys Acta | 2018 | Belosludtsev KN, Belosludtseva NV, Talanov EY, Tenkov KS, Starinets VS, Agafonov AV, Pavlik LL, Dubinin MV (2018) Effect of bedaquiline on the functions of rat liver mitochondria. Biochim Biophys Acta 1861:288-97. | Rat | Liver |
