Kynurenine hydroxylase: Difference between revisions
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'''Kynurenine hydroxylase''' catalyzes the chemical reaction: L-kynurenine + NADPH + H<sup>+</sup> + O<sub>2</sub> ↔ 3-hydroxy-L-kynurenine + NADP<sup>+</sup> + H<sub>2</sub>O | '''Kynurenine hydroxylase''' catalyzes the chemical reaction: L-kynurenine + NADPH + H<sup>+</sup> + O<sub>2</sub> ↔ 3-hydroxy-L-kynurenine + NADP<sup>+</sup> + H<sub>2</sub>O | ||
Kynurenine hydroxylase belongs to the family of oxidoreductases acting on paired donors, with O<sub>2</sub> as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O<sub>2</sub> with NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor. This enzyme participates in tryptophan metabolism. It employs one cofactor, FAD. | |||
Revision as of 11:40, 21 May 2012
- high-resolution terminology - matching measurements at high-resolution
Kynurenine hydroxylase
Description
Kynurenine hydroxylase (kynurenine 3-monooxygenase) is located in the outer mitochondrial membrane.
MitoPedia topics:
Enzyme
Kynurenine hydroxylase catalyzes the chemical reaction: L-kynurenine + NADPH + H+ + O2 ↔ 3-hydroxy-L-kynurenine + NADP+ + H2O
Kynurenine hydroxylase belongs to the family of oxidoreductases acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor. This enzyme participates in tryptophan metabolism. It employs one cofactor, FAD.
